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James P Allison and Tasuku Honjo Win Nobel Prize For Medicine (theguardian.com)
An American and a Japanese scientist have won the 2018 Nobel prize in physiology or medicine for discovery of a revolutionary approach to cancer treatment. The Institute -- 50 professors at the Stockholm facility -- chose the winners of the prize honoring research into the microscopic mechanisms of life and ways to fend off invaders that cut it short. From a report: James Allison and Tasuku Honjo will share the 9m Swedish kronor (roughly $1 million) prize, announced by the Nobel Assembly at the Karolinska Institute in Stockholm. The two scientists have been awarded the prize for their discovery that the body's immune system can be harnessed to attack cancer cells.
The immune system normally seeks out and destroys mutated cells, but cancer cells find sophisticated ways to hide from immune attacks, allowing them to thrive and grow. Many types of cancer do this by ramping up a braking mechanism that keeps immune cells in check. The discovery is transforming cancer treatments and has led to a new class of drugs that work by switching off the braking mechanism, prompting the immune cells to attack cancer cells. The drugs have significant side effects, but have been shown to be effective -- including, in some cases, against late-stage cancers that were previously untreatable. The physics prize is to be announced Tuesday, followed by chemistry. The winner of the Nobel Peace Prize will be named Friday. No literature prize is being given this year.
The immune system normally seeks out and destroys mutated cells, but cancer cells find sophisticated ways to hide from immune attacks, allowing them to thrive and grow. Many types of cancer do this by ramping up a braking mechanism that keeps immune cells in check. The discovery is transforming cancer treatments and has led to a new class of drugs that work by switching off the braking mechanism, prompting the immune cells to attack cancer cells. The drugs have significant side effects, but have been shown to be effective -- including, in some cases, against late-stage cancers that were previously untreatable. The physics prize is to be announced Tuesday, followed by chemistry. The winner of the Nobel Peace Prize will be named Friday. No literature prize is being given this year.
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Detestable villains - mean spirited, bigoted, belligerent, vicious - are using underhanded tricks to force hypocritical "Codes of Conduct" on the projects we built.
The only purpose of these CoCs is to allow so-called "Progressives" to conduct witch hunts against anyone who opposes them. Thereby they plan to steal our work for their shadowy corporate paymasters.
You can readily tell these CoCs are not about "just being nice" - because they are ALWAYS supported by the very LEAST NICE, most aggressively mean and shamelessly bigoted people you can imagine.
If a project to which you contribute has been raped by CoC-mongers there is a simple solution: WALK AWAY. Never contribute again. If you have a patch almost ready, count the time you spent on it as a loss and throw it away. If you see a security issue, remain silent and do nothing. IT'S NO LONGER YOUR PROJECT. YOU ARE NOT WELCOME THERE.
If you are evaluating new software, don't even consider any projects burdened under the tyranny of a CoC. It doesn't matter if they are technically superior - just don't consider them. Never be openly political, always make up a technical reason for rejecting CoCed projects.
Don't argue in public about the CoC. Doing so only exposes you to needless risk. You might be dis-employed, blackballed, and even set up for a #MeToo purge. Just stay far away.
Comrades: Individually we are powerless, and easily crushed beneath the iron boot of Corporate Social Just-Us. But together in solidarity we are millions and we are strong. The Internet itself depends on our collective labor. If we stop working, the internet stops working.
Free Software developers, save yourselves and save your communities! Just WALK AWAY from any project with a CoC. Without our labor they are nothing.
You ain't seen nothing yet!
According to my Slashdot trolls, I will receive a Nobel prize too as well...
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>"The immune system normally seeks out and destroys mutated cells, but cancer cells find sophisticated ways to hide from immune attacks"
That is strange wording. Cancer cells are not autonomous, learning, clever, and planning. They are just mutations that "happen", randomly due to replication errors and external events (like radiation, viruses, and chemicals). Sometimes there just happen to be cells that mutate in a way that the immune system doesn't recognize. We all have cancer cells in our bodies, probably all the time, and normally they are caught and killed by our immune systems. The above statement makes it sound like they are planning something with a "will" :)
This morning they announced a two year prison sentence for rape, against the husband of one of the Swedish Academy members, that scandal is the reason there will be no Literature price this year.
Terje
"almost all programming can be viewed as an exercise in caching"
Comment removed based on user account deletion
Comment removed based on user account deletion
That is strange wording. Cancer cells are not autonomous, learning, clever, and planning.
It's not strange wording at all. Sophistication is a statement of what something is, not how it was arrived at. Things don't have to have intelligent thought behind them to be sophisticated. Trees do not have what we regard as intelligence but you'd be hard pressed to argue that a tree leaf isn't an astonishingly sophisticated thing. Enormous sophistication and complexity can arise from very simple processes and evolution - no clever learning or planning required.
No literature prize is being given this year
They should really start reading slashdot.
Slashdot, fix the reply notifications... You won't get away with it...
.
What a bunch of losers. Which I at least know how to spell.
.
How about some info on how they managed to get immune system to discriminate well enough between cancer and normal cells (which have nearly the same DNA) well enough to make this more good than harmful? What about reasoned discussion of this and alternate approaches? Not here. Disgusting.
Why guess when you can know? Measure!
I saw "no literature prize" and wondered what dead writer the Norwegian Nobel Institute was considering. The Institute doesn't award posthumous prizes, which is why it withheld its Peace Prize in 1948 in memory of Mohandas Gandhi.
See subject: his FAKEname on a post impersonating me https://linux.slashdot.org/com... & altering /.er's words.
c6gunner tried to mock me 1st https://linux.slashdot.org/com...
So I challenge c6gunner to show he did better work than mine & he CAN'T!
YOU DEMAND PROOF of others here? "I've yet to see you provide any evidence of that." by c6gunner on Monday March 15, 2010 @10:02PM (#31490942) ?
So now I DEMAND IT OF YOU & YOU FAIL!
c6gunner = "Run, Forrest: RUN!!!
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SECURITY PROS https://slashdot.org/comments....
REAL RESULTS w/ hosts vs. threats https://slashdot.org/comments....
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Can medicine not actually *cure* anything anymore? This seems like something someone should have got a pat on the head and a "good job" from their research lead on, not a fuxxoring Nobel Prize. Note that they didn't give one in literature this year. Good. When there aren't Nobel-worth advances, then there shouldn't be Nobel prizes. Giving them out anyway waters them down (as if the stupid Peace Prizes to genocidal politicians weren't bad enough). From my lay perspective medical advances in the last 30 years have been weak, AF. They haven't really cured anything or significantly made people healthier or live longer. The only thing they seem to have become really really good at is billing.
From my lay perspective medical advances in the last 30 years have been weak, AF.
Over the last 30 years, average live expectancy has gone up by 5 years.
The only thing they seem to have become really really good at is billing.
That is an American problem. It doesn't much affect the other 95% of the world.
See subject: his FAKEname on a post impersonating me https://linux.slashdot.org/com... & altering /.er's words.
c6gunner tried to mock me 1st https://linux.slashdot.org/com...
So I challenge c6gunner to show he did better work than mine & he CAN'T!
YOU DEMAND PROOF of others here?
"I've yet to see you provide any evidence of that." by c6gunner on Monday March 15, 2010 @10:02PM (#31490942) ?
So now I DEMAND IT OF YOU & YOU FAIL!
c6gunner = "Run, Forrest: RUN!!!
* c6gunner's LYING saying I did a MacOS X one - I haven't yet & c6gunner's LYING impersonating me hosts work vs. Intel CPU issues (spectre/meltdown).
APK
P.S.=> You say hosts = shit here https://slashdot.org/comments.... ?
FACTS: /.ers & security pros + RESULTS say DIFFERENT:
1st: /.ers https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments....
2nd: SECURITY PROS https://slashdot.org/comments....
3rd: REAL RESULTS w/ hosts vs. threats https://slashdot.org/comments....
EAT YOUR WORDS
I'm sorry, but that is such an uninformed statement, that it borders on deliberate trolling.
Do you have any idea that the therapies they are talking about with the immune system being modified to specifically target and eradicate leukemia are actually the bright spots in medicine, with 'cure' being the most appropriate word?
See for example:
https://www.nejm.org/doi/full/10.1056/NEJMoa1407222
These were people with leukemia that was not responding to the best in standard treatments, and they used these personalized T-cell immunotherapy treatments and basically cured these people. No ongoing treatments. Just the one time treatment.
Honestly. What is the difference between willful ignorance and trolling at this point?
Please - if you are uninformed and can't even bother to do some basic investigating, please shut the hell up, stay off the internet, and stop making the world a worse place with your whining, tangential logic, and misinformation, because you are not helping the world in any way.
Stay off of Slashdot!
See subject: his FAKEname on a post impersonating me https://linux.slashdot.org/com... & altering /.er's words.
c6gunner tried to mock me 1st https://linux.slashdot.org/com...
So I challenge c6gunner to show he did better work than mine & he CAN'T!
YOU DEMAND PROOF of others here?
"I've yet to see you provide any evidence of that." by c6gunner on Monday March 15, 2010 @10:02PM (#31490942) ?
So now I DEMAND IT OF YOU & YOU FAIL!
c6gunner = "Run, Forrest: RUN!!!
* c6gunner's LYING saying I did a MacOS X one - I haven't yet & c6gunner's LYING impersonating me hosts work vs. Intel CPU issues (spectre/meltdown).
APK
P.S.=> You say hosts = shit here https://slashdot.org/comments.... ?
FACTS: /.ers & security pros + RESULTS say DIFFERENT:
1st: /.ers https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments.... https://slashdot.org/comments....
2nd: SECURITY PROS https://slashdot.org/comments....
3rd: REAL RESULTS w/ hosts vs. threats https://slashdot.org/comments....
EAT YOUR WORDS!!!
Bull shit! 95% of the world is paying for it already, transparently through increased taxation.
Healthcare isn't free. It never was. Anyone that says otherwise is either lying, ignorant, or both.
Life is not for the lazy.
So, they cured cancer/malaria/AIDS in Europe? Oh, wait, you spouted some ridiculous bullshit about "life expectancy" instead of any real evidence or thought. I've lived in Europe before myself (Norway). I remember people waiting months to see a specialist, in the second richest country (per capita) in Europe. So, yeah, they couldn't figure out the billing or the actual care, either. I'm not exactly itching to sign onto that garbage. The only difference between strutting doctors that are full of shit over their non-accomplishments in the USA versus Europe is how much less they have to work in Europe.
First off, fuck you. Second, that study is all you got after throwing all those grenades? What a load of shit, Coward. That fucking study has 30 people in it. What about the other 174,200 people in the USA alone that aren't getting your wonder-cure? If it's a cure, why didn't anyone else pick up on that, or is everyone else just not as smart as you? It's full of shit AC's like you that need to stay the fuck off the cain and /.