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James P Allison and Tasuku Honjo Win Nobel Prize For Medicine (theguardian.com)
An American and a Japanese scientist have won the 2018 Nobel prize in physiology or medicine for discovery of a revolutionary approach to cancer treatment. The Institute -- 50 professors at the Stockholm facility -- chose the winners of the prize honoring research into the microscopic mechanisms of life and ways to fend off invaders that cut it short. From a report: James Allison and Tasuku Honjo will share the 9m Swedish kronor (roughly $1 million) prize, announced by the Nobel Assembly at the Karolinska Institute in Stockholm. The two scientists have been awarded the prize for their discovery that the body's immune system can be harnessed to attack cancer cells.
The immune system normally seeks out and destroys mutated cells, but cancer cells find sophisticated ways to hide from immune attacks, allowing them to thrive and grow. Many types of cancer do this by ramping up a braking mechanism that keeps immune cells in check. The discovery is transforming cancer treatments and has led to a new class of drugs that work by switching off the braking mechanism, prompting the immune cells to attack cancer cells. The drugs have significant side effects, but have been shown to be effective -- including, in some cases, against late-stage cancers that were previously untreatable. The physics prize is to be announced Tuesday, followed by chemistry. The winner of the Nobel Peace Prize will be named Friday. No literature prize is being given this year.
The immune system normally seeks out and destroys mutated cells, but cancer cells find sophisticated ways to hide from immune attacks, allowing them to thrive and grow. Many types of cancer do this by ramping up a braking mechanism that keeps immune cells in check. The discovery is transforming cancer treatments and has led to a new class of drugs that work by switching off the braking mechanism, prompting the immune cells to attack cancer cells. The drugs have significant side effects, but have been shown to be effective -- including, in some cases, against late-stage cancers that were previously untreatable. The physics prize is to be announced Tuesday, followed by chemistry. The winner of the Nobel Peace Prize will be named Friday. No literature prize is being given this year.
When did cdreimer become Slashdot's whipping boy?
Mostly random stuff.
When a bunch of retarded trolls with too much time on their hands decided to bully him, and the rest of slashdot, including moderators, decided to either idly stand by or participate.
The continued allowance of campaigns like this is one of the signs of how slashdot has turned into a far right cesspool of stupidity.
Captcha; "predicts". Yeah "-1 I hate you and while I have no arguments, I have modpoints", here we come.
>"The immune system normally seeks out and destroys mutated cells, but cancer cells find sophisticated ways to hide from immune attacks"
That is strange wording. Cancer cells are not autonomous, learning, clever, and planning. They are just mutations that "happen", randomly due to replication errors and external events (like radiation, viruses, and chemicals). Sometimes there just happen to be cells that mutate in a way that the immune system doesn't recognize. We all have cancer cells in our bodies, probably all the time, and normally they are caught and killed by our immune systems. The above statement makes it sound like they are planning something with a "will" :)
This morning they announced a two year prison sentence for rape, against the husband of one of the Swedish Academy members, that scandal is the reason there will be no Literature price this year.
Terje
"almost all programming can be viewed as an exercise in caching"
That is strange wording. Cancer cells are not autonomous, learning, clever, and planning.
It's not strange wording at all. Sophistication is a statement of what something is, not how it was arrived at. Things don't have to have intelligent thought behind them to be sophisticated. Trees do not have what we regard as intelligence but you'd be hard pressed to argue that a tree leaf isn't an astonishingly sophisticated thing. Enormous sophistication and complexity can arise from very simple processes and evolution - no clever learning or planning required.
No literature prize is being given this year
They should really start reading slashdot.
Slashdot, fix the reply notifications... You won't get away with it...
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What a bunch of losers. Which I at least know how to spell.
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How about some info on how they managed to get immune system to discriminate well enough between cancer and normal cells (which have nearly the same DNA) well enough to make this more good than harmful? What about reasoned discussion of this and alternate approaches? Not here. Disgusting.
Why guess when you can know? Measure!
I saw "no literature prize" and wondered what dead writer the Norwegian Nobel Institute was considering. The Institute doesn't award posthumous prizes, which is why it withheld its Peace Prize in 1948 in memory of Mohandas Gandhi.
Well, the Norwegian Institute doesn't award the literature prize so it doesn't really matter who they consider.
Besides, there have been other occasions when no prize was awarded, sometimes for the reason that they didn't think anyone deserved it.
From my lay perspective medical advances in the last 30 years have been weak, AF.
Over the last 30 years, average live expectancy has gone up by 5 years.
The only thing they seem to have become really really good at is billing.
That is an American problem. It doesn't much affect the other 95% of the world.
Bull shit! 95% of the world is paying for it already, transparently through increased taxation.
Healthcare isn't free. It never was. Anyone that says otherwise is either lying, ignorant, or both.
Life is not for the lazy.
So, they cured cancer/malaria/AIDS in Europe? Oh, wait, you spouted some ridiculous bullshit about "life expectancy" instead of any real evidence or thought. I've lived in Europe before myself (Norway). I remember people waiting months to see a specialist, in the second richest country (per capita) in Europe. So, yeah, they couldn't figure out the billing or the actual care, either. I'm not exactly itching to sign onto that garbage. The only difference between strutting doctors that are full of shit over their non-accomplishments in the USA versus Europe is how much less they have to work in Europe.
First off, fuck you. Second, that study is all you got after throwing all those grenades? What a load of shit, Coward. That fucking study has 30 people in it. What about the other 174,200 people in the USA alone that aren't getting your wonder-cure? If it's a cure, why didn't anyone else pick up on that, or is everyone else just not as smart as you? It's full of shit AC's like you that need to stay the fuck off the cain and /.