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Fasting Can Improve Overall Health By Causing Circadian Clocks In the Liver and Skeletal Muscle To Rewire Their Metabolism, Study Finds (sciencedaily.com)

An anonymous reader quotes a report from ScienceDaily: In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports. The research was conducted using mice, which were subjected to 24-hour periods of fasting. While fasting, researchers noted the mice exhibited a reduction in oxygen consumption (VO2), respiratory exchange ratio (RER), and energy expenditure, all of which were completely abolished by refeeding, which parallels results observed in humans.

"The reorganization of gene regulation by fasting could prime the genome to a more permissive state to anticipate upcoming food intake and thereby drive a new rhythmic cycle of gene expression. In other words, fasting is able to essentially reprogram a variety of cellular responses. Therefore, optimal fasting in a timed manner would be strategic to positively affect cellular functions and ultimately benefiting health and protecting against aging-associated diseases." This study opens new avenues of investigation that could ultimately lead to the development of nutritional strategies to improve health in humans.

2 of 216 comments (clear)

  1. Re: Don't like the science? Wait a few years by x0ra · · Score: 5, Insightful

    by definition, it *is*, as "breakfast" is litterally the "breaking of the period of fast" :-/

  2. Re:Don't like the science? Wait a few years by jma05 · · Score: 5, Insightful

    Most of what had been "known" for millennia was wrong. That is the whole point of doing science.
    But even a broken clock can be right twice a day.
    The scientific process for doing dietary studies though is less than stellar today. But that can be fixed.
    Science is working, not "struggling". Never before in human history has so much been uncovered in such a short time.

    > "religions" are just archetypes of human biology pattern

    If so, we would not have so many religions. Religions occasionally are codifications of natural human behavior - social, more than biological. Other times, they deny natural human behavior.