New US Experiments Aim To Create Gene-Edited Human Embryos (npr.org)

An anonymous reader quotes a report from NPR: A scientist in New York is conducting experiments designed to modify DNA in human embryos as a step toward someday preventing inherited diseases, NPR has learned. For now, the work is confined to a laboratory. But the research, if successful, would mark another step toward turning CRISPR, a powerful form of gene editing, into a tool for medical treatment. Dieter Egli, a developmental biologist at Columbia University, says he is conducting his experiments "for research purposes." He wants to determine whether CRISPR can safely repair mutations in human embryos to prevent genetic diseases from being passed down for generations. So far, Egli has stopped any modified embryos from developing beyond one day so he can study them. "Right now we are not trying to make babies. None of these cells will go into the womb of a person," he says. But if the approach is successful, Egli would likely allow edited embryos to develop further to continue his research. Egli's research is reviewed in advance and overseen by a panel of other scientists and bioethicists at Columbia. Specifically, Egli is trying to fix one of the genetic defects that cause retinitis pigmentosa, an inherited form of blindness. "If it works, the hope is that the approach could help blind people carrying the mutation have genetically related children whose vision is normal," reports NPR.

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as a step toward someday preventing inherited diseases

"the hope is that the approach could help blind people carrying the mutation have genetically related children whose vision is normal"

Very surprisingly to me, this is generally NOT an immediate accepted topic / action / result. IT'S GONE NOW -- I read it and was shocked. I immediately thought of Ender's Game book 3? where the ?antagonist? -- who had to start and follow wood grain lines until the gods were satisfied -- didn't want to be cured, but also couldn't disrespect her father, so was cured against her will.

There was an article (actually, an opinion piece) that was (not any more!) at: https://www.pluralist.com/post....

It said: A prominent disabilities activist spoke against the use of genetic editing to eliminate diseases from birth because it would be tantamount to a "genocide" against the culture of the disabled.

Link. Other link Discussion

We're talking about removal of diseases," she said. "That's forever. That's a change -- a modification -- that will be passed on to future generations. So that's actually genocide. It's a form of eugenics where certain lived experiences are seen as undesirable and unimaginable."

... argued that disabled people are a community unto themselves and that eliminating their conditions means erasing the potential future of their culture. She asked, "Where is the line between what society perceives to be a horrible genetic mutation and someone's culture?"

The Eye of the Beholder

I'm like: DO IT. And do it AGAIN just to make sure. And if you're bored, check to see if you need to do it AGAIN. If you want to be deaf, you can always stick bananas in your ears. Or your eyes. Or any other random orifices.