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Feeding an Appetite-Suppressing Human Drug To Mosquitos Make Them Lose Their Attraction To Blood By Around 80%: Study (nature.com)

From Nature magazine: Female Aedes aegypti, like other mosquito species, feed on blood to get the protein they need to produce their eggs, and spread diseases such as dengue in the process. But once the mosquitoes have had their blood fix, they stop biting until they've laid their eggs several days later. Leslie Vosshall, a neurobiologist at the Rockefeller University in New York City, wondered whether she could hijack this biological process to switch off a mosquito's appetite.

Previous research had suggested that a mosquito's desire to feed is controlled by neuropeptides, molecules used by the nervous system to communicate. Vosshall and her team suspected that neuropeptide Y (NPY) receptors might be particularly important, because they form part of the molecular pathway involved in food-seeking behaviour for many animals -- including humans. Some human appetite-suppressant drugs already target the NPY receptors, so Vosshall decided to take a "completely zany" approach: feed these drugs to mosquitoes and see what happens. The method worked: mosquitoes that fed on a solution containing NPY-activating drugs were much less likely to approach a human-scented 'lure' than were the control group, and their appetites remained suppressed for two days.
Further reading: A New Way to Keep Mosquitoes From Biting.

7 of 71 comments (clear)

  1. Bah by sunking2 · · Score: 4, Insightful

    Feeding them poison reduces it 100%

    1. Re:Bah by ShanghaiBill · · Score: 2, Insightful

      Feeding them poison reduces it 100%

      ... until they develop resistance. But they would have strong selective pressure to develop resistance to the appetite suppressor as well.

    2. Re:Bah by Anonymous Coward · · Score: 3, Interesting

      We should use CRISPR to create a version of the mosquito that gets the protein from some source other than blood. Make them more fertile and with stronger mate-attraction characteristics than the existing mosquitoes, and release them into the wild.

      Then they will still be there to feed frogs and what-not, but they won't be giving us diseases. It's a win-win.

  2. Re:I still prefer the laser solution by alvinrod · · Score: 2, Interesting

    In case anyone wasn't aware of these yet, the videos demonstrating how they work are pretty damn cool. Here's one that has slow motion captures of such a laser in action. It doesn't have any audio, but the whole thing is even more awesome if you open a video playing Wagner's Ride of the Valkyries in another tab.

  3. Re:I don't want them to stop biting. by CaptainDork · · Score: 2

    So let's solve the real problem: Genetically engineer pest-resistant humans.

    --
    It little behooves the best of us to comment on the rest of us.
  4. Better Idea by ememisya · · Score: 2

    I suggest cyclopentolate. One drop on each eye and the mosquito will not be able to see where it's going for several hours.

  5. Fake blood? by HaaPoo · · Score: 2

    Same as many vampire movies, why do not we develop fake blood that taste better than human blood, and setup feeding stations for them. They may leave us alone.