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We Transition Between 19 Different Brain Phases When Sleeping, Study Finds (newatlas.com)

A new study suggests that instead of the traditional four sleep stages we generally understand the brain moves through, there are in fact at least 19 different identifiable brain patterns transitioned through while sleeping. New Atlas reports: Traditionally scientists have identified four distinct stages our brain transitions through in a general sleep cycle -- three non-REM sleep phases (N1-3) that culminate in an REM phase. The four stages have been classically determined and delineated using electroencephalographic (EEG) brainwave recordings. The new research set out to more comprehensively record whole-brain activity in a number of subjects by using functional magnetic resonance imaging (fMRI). The study began by studying 57 healthy subjects in an fMRI scanner. Each subject was asked to lie in the scanner for 52 minutes with their eyes closed. At the same time, each subject was tracked using an EEG. This allowed the researchers to compare traditional brainwave sleep cycle data with that from the fMRI.

Due to the limited duration of the fMRI data, no subjects were found to enter REM sleep, however, 18 subjects did completely transition from wakefulness through the three non-REM sleep phases according to the EEG data. Highlighting the complexity of brain activity during our wake-to-sleep cycle the researchers confidently chronicled 19 different recurring whole-brain network states. Mapping these whole-brain states onto traditional EEG-tracked sleep phases revealed a number of compelling correlations. Wakefulness, N2 sleep and N3 sleep all could be represented by specific whole brain states. The range of different fMRI-tracked brain states did reduce as subjects fell into deeper sleep phases, with two different fMRI brain states correlating with N2 sleep, and only one with N3. However, N1 sleep as identified by EEG data, the earliest and least clearly defined sleep phase, did not consistently correspond with any fMRI brain state. The researchers conclude from this data that N1 is actually a much more complex sleep phase than previously understood. This phase, a strange mix of wakefulness and sleep, seemed to encompass a large range of the 19 different whole-brain network states identified in the fMRI data.
The research was published in the journal Nature Communications.

1 of 37 comments (clear)

  1. Re:MRI is not sleep-friendly by ckatko · · Score: 3, Informative

    Uhh, plenty of people fall asleep in MRI machines all the time. It's loud, but you wear headphones (that optionally play music) and the loud noises are periodic. And, because you're laying down and stuck immovable for sometimes over an hour, it's natural to start falling asleep.

    I've had at least 5 MRIs and lab techs from two different buildings have told me they have people fall asleep all the time.

    https://www.quora.com/Have-you...

    https://www.reddit.com/r/tifu/...

    http://1goodfoot.blogspot.com/...

    https://multiplesclerosis.net/...

    [thousands of etc examples]