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Immune Cells May Play a Role In Causing Cavities (newatlas.com)
Researchers at the University of Toronto have found that cavities may be collateral damage from an overzealous immune system. New Atlas reports: Traditionally, bacteria have taken most of the blame for cavities and tooth decay. The bugs cling to your teeth as plaque and produce acid as waste, which dissolves tooth enamel, dentin and even filling material. But the new study suggests the story is more complicated than that. Oral immune cells called neutrophils are dispatched by the body in response to invading bacteria -- but the researchers found that they might be a little careless in the battle.
On their own, neutrophils can't damage teeth but the problems arise after acids from bacteria demineralize them. Once weakened, enzymes released by the neutrophils could wreak havoc on other tooth substances. Damage was found to appear in a matter of hours, and worse still, it also seems to apply to tooth-colored fillings, which may explain why they tend to fail within five to seven years. The silver lining of the discovery is that it could lead to new types of treatment, or new standards for testing materials that are to be used in fillings. The research was published in the journal Acta Biomateralia.
On their own, neutrophils can't damage teeth but the problems arise after acids from bacteria demineralize them. Once weakened, enzymes released by the neutrophils could wreak havoc on other tooth substances. Damage was found to appear in a matter of hours, and worse still, it also seems to apply to tooth-colored fillings, which may explain why they tend to fail within five to seven years. The silver lining of the discovery is that it could lead to new types of treatment, or new standards for testing materials that are to be used in fillings. The research was published in the journal Acta Biomateralia.
This is obvious, I don't get it...
Does methamphetamine overstimulate neutrophils and cause methmouth?
"Immune Cells May Play a Role In Causing Cavities"
The key word is "may".
The issues are not being fully explored.
I drink sugary acidic drinks (soda) all the time but don't get cavities. I'm going to assume it's the phosphoric acid killing off the bacteria, so maybe acidic foods don't cause cavities after all?
Seems candy does cause cavities though, from what I can tell, maybe because the sugar is not accompanied by water to wash out the bacteria or no acid to limit the types that can survive?
When I dump what is nearly pure sugar into my mouth, added by starches that stick to my teeth, that both cause a massive inflammation of the bacteria that digest that, I *expect* my immune system to put the pedal to the metal and go carpet bombing!
What did you expect??
Typical pseudo-scientific "medical" research again, blaming the organ for the blood it spills from the knife stuck into it.
Who financed this "research" again?
I follow a carnivore diet, on which I dropped 70 pounds and halted my internal inflammation. So no sugar or plants.
6 months in, I went to the dentist.
The hygenist was doing her thing. The dentist walked in and asked "So how is he doing with his flossing?"
The hygenist said "Perfectly - he'd been keep it clean between his teeth, there is zero build up and his gums aren't inflamed any more".
But I had not brushed or flossed once.
So plants and sugar that promote inflammation also contributes to the tooth decay. This is n=1 supportive evidence of that finding.
I should use this sig to advertise my book ISBN-13 : 978-1501515132.
Or pure acellular starches.
It's not food.
Food comes in cells. Not white powdered drugs.
And when you chose to do drugs ... (You own your body!) ... don't be surprised if they fuck you up like drugs.
I'm not sorry for the harsh words. This is what harsh words were made for.
The bits that stick to your teeth are like cavity glue.
And: The acid in those drinks will melt away your enamel anyway.
Trust me, you WILL get cavities. All over. And your gums will loosen until your teeth become loose and rot from below.
Give it some 10 years.
Our body is extremely good at keeping up the balances in the face of what should be deadly. But not forever. Most age-related diseases are not from old age, but from decades of bad nutrition and bad behavior.
And their solution is to never see a dentist, or a toothbrush. Let the immune system deal with it, is the Brit's motto.
I know we've seen worse in science reporting, but 'overzealous' is not a helpful term to use in describing the immune system.
They still saying acid produced by bacteria is the underlying cause, so nothing new there, *but* they've identified a mismatch between the immune system's strategy for responding to the bacteria and the altered chemical environment created by said bacteria, and that insight potentially could prove very valuable in determining improved treatments.
always append "in mice"
" EVERY vital sign is optimized and my teeth are excellent. " = Just more worthless nonsense anecdote from boasting online about bullshit pet causes, throw it on the pile, the plural of which still is not "data" or "veritas"
"God did not give us defective teeth that need such treatment." GOD didn't invent human teeth. The diet of simian ancestors did, and it sure AF wasn't some flaky fad Keto diet back then either, nope.
"The dental industry push to brush & floss daily is superstition at best, subterfuge at worst." - And now you've gone full meth mouth with the non-science? DAILY isn't even brushing half as much as the recommendation lol! Disgusting.
I just spoke to God, he's not responsible for your pseudo-science dietary habits or lack of hygiene, sorry.
Thus speaketh an anonymous coward who has ignored the huge mass of scientific evidence to appear in recent years.
I should use this sig to advertise my book ISBN-13 : 978-1501515132.
But it'll feel like it.
Lectins are also at high concentrations in just about all seafood, you have no idea because you're not a dietitian.
Cite some actual science so you can stop relying on bullshit anecdotes then. So far you don't know your breath stinks, it's really not evidence of anything except your own undeserved self esteem and self-reinforced routines.
Ol Olsoc c6gunner raymorris do deserve it though
I have hard teeth. First cavity was in my 50's. I've had 2. Mom also had hard teeth. Her first was in her 60's. I grew up poor, saw the dentist maybe 3 times before I was 23. At 23, had my first cleaning. It was rough. The negative with hard teeth is often you have issues with plaque. Now I get cleanings 3X/year. Pretty painless.
Go find it, you lazy coward. Google works. Weston A. Price published his findings 80 years ago and the data hasn't magically changed since. We didn't evolve with toothbrushes or sugar.
I should use this sig to advertise my book ISBN-13 : 978-1501515132.
You are avoiding the issue. Experiments are being communicated in a way that is not correct. Articles are not making the uncertainties clear.
Well, I'm 31 and have yet to get a cavity.
I don't know how common or not that is. or what to make of that.
I guess I just take care of brushing and flossing regularly, no secret.
If it's caused by the immune system is it still a cavity, or is it tooth resorption?
One of our competitors trademarked the term "hypothesis". From now on, we will call them "boneheaded ideas".
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