Regardless of where you are on the rage spectrum, you should consider temporarily canceling your plan (but perhaps not your account). If there's a sudden move for the doors (even if most of us were only planning on staying outside for an hour or two), it could send a powerful message. Hold out for as long as you can; if you can't stand it, reactivating your account is easy because they retain everything. But at least take the step beyond anonymous internet rage and cancel your plan, for as long as you can.
BTW I guess it wasn't clear from the above, but I expect that the estimate in the paper is low-balling it; the inadequacy of our methods lead to a lot of false negatives.
I think it's woefully premature to generalize the results of this study to the entirety of humanity. These results are based off of the whole genome sequencing of *2* families, and as far as our technology and analytical methods have come, they still leave a lot to be desired. Besides, the key message isn't that we have a conclusive de novo mutation rate for humans (which we don't), but that the rate and mechanism of their creation can vary widely from family to family.
...well, it hasn't passed the House, for that matter. The vote just means it made it out of committee.
Regardless of where you are on the rage spectrum, you should consider temporarily canceling your plan (but perhaps not your account). If there's a sudden move for the doors (even if most of us were only planning on staying outside for an hour or two), it could send a powerful message. Hold out for as long as you can; if you can't stand it, reactivating your account is easy because they retain everything. But at least take the step beyond anonymous internet rage and cancel your plan, for as long as you can.
BTW I guess it wasn't clear from the above, but I expect that the estimate in the paper is low-balling it; the inadequacy of our methods lead to a lot of false negatives.
I think it's woefully premature to generalize the results of this study to the entirety of humanity. These results are based off of the whole genome sequencing of *2* families, and as far as our technology and analytical methods have come, they still leave a lot to be desired. Besides, the key message isn't that we have a conclusive de novo mutation rate for humans (which we don't), but that the rate and mechanism of their creation can vary widely from family to family.
I'm making a note here: huge success.
Is there anything ironic about the self-appointed "voice of free speech" trying to bully an admittedly annoying and vocal cult into silence?