It's kind of funny sometimes. Like when EA did the humble bundle, essentially giving away medal of honor and some other games that were worth at least a dollar. I installed it, updated it, and later tried booting it up offline.
No go: the basically free game which was three years old needed an online connection, even for single player. You know, to make sure I donated at least a penny to the EFF for the game instead of just pirating it.
At least it sounds like they have an actual reason this time. They didn't used to bother explaining it. It was just
Apple: Here's your new phone, and you'll want to buy a new cord too.
Customer: Oh no thanks, I have the old one.
Apple: That one won't work anymore, the new one is $40!
Customer: Wait, why won't it work? It's exactly the same.
Apple: It's incompatible with the new phone.
Customer: It IS compatible! See, I can plug it in!.. and it's telling me it's not compatible?
Apple: Yes, because it's incompatible.
Customer: Why is it incompatible!?! It fits and carries electricity still!
Apple: Because when you plug it in, the phone tells you it's incompatible and stops itself from charging... duh...
Customer: This seems like you artificially made the phone incompatible with old cords just to nickle and dime me for new accessories!
Apple: No sir, it costs forty dollars, not fifteen cents.
There's no reasoning someone out of a position they didn't reason themselves into. Clearly, you want to believe that there is a crisis in education and parenting and are unable to consider anything that doesn't justify your position on the matter. So I give up, and I'll just say I'm glad you have limited control of education and parenting.
Forget moral compass, logical thought completely disappears. "Comcast did or said something, or something happened or was said to comcast: prepare for the internet to get slower and the bill to go up, and some assholes to blabber on about freedoms from government intrusion."
They already have.. We have the KKK to thank for that precedent, but it would have happened anyway with protests.
Of course, it's not always good idea to wear masks at protests anyway: agent provocateurs can easily infiltrate, start violence, and then give the police an excuse to shut it down. Needless to say, anti-mask laws don't apply to police.
No problem. I just have several friends who are teachers, both by profession and by calling. This is one of their favourite talking points after they get a few drinks into them. The friction is there, and it's definitely increasing.
That's still anecdotal evidence. Even if these friends of yours have been teaching for the last 30 years, that's still not very reliable unless they've found a way to quantify that it's getting worse.
Note that you yourself agree that number has tripled over just 40 years. I find it strange that you would consider that tripling of demand for certain services that require heavy investment and long term preparation will not generate friction between consumers of said services and providers.
Nonsense. The article said the proportion of mothers 35 or older has tripled in the past 40 years. That doesn't represent a tripling of demand from schools.
"Nowadays?" That and your unquantified charge that "schools used ter be about LEARNING, now they're about BABYSITTIN!" makes me think you're romanticizing the past.
Parents haven't changed that much. The percentage of women aged 35 or older having children increased from 5% in the 70's... to about 15% today. We're not talking about a fundamental change in society here. Schools have always been partly about taking the kids off parents' hands for a while. Nannies weren't invented anytime recently. Boarding schools are pretty rare these days.
I also really don't think there's evidence of "a large amount of friction in many countries" in relation to kids and parents compared to years past. Kids and parents of any age don't get along, but things turn out okay.
Without data to back up your claim that older parents are worse, I'd suggest the opposite hypothesis: that older parents have less of a struggle to support their children, have to spend less time at work to do so, and thus are better parents.
Lets not say the sky is falling, because it doesn't appear to be doing so and in general almost never does. I know it's fun to run around squawking that we're doomed, but citations are needed before I'll allow it to continue.
Predictions aren't facts no matter how certain you are of them, so "These are the facts" isn't really accurate. Aside from that I sadly can't disagree.
I'd say "it sucked" goes for almost all mobile games. Most non-mobile games aren't great, but the amount of shovelware seems much lower on consoles and PC.
When is "mobile game" going to mean more than shitty controls and everything else? The best games at best seem to be "good" only when judged by the standard of "compared to what else I could be doing on a plane."
Even with handheld game systems with decent controls, like the DS, there were few games that I'd choose to play if I could be playing on a PC or console. I personally don't believe that more computing power will inevitably make console or PC games better, I think it's just a problem of lower expectations for mobile games. We're used to 99.9% of mobile games being shit. Compare the amount of shit EA got for Sim city 5 vs the iOS dungeon keeper. About the same level of complaints from what I could see, but the two games didn't seem to be the same level of shitty. Sim City 5 had some technical problems. Dungeon keeper was fundamentally some asshole asking you for change over and over again. EA deserves much more shit for dungeon keeper, but we're used to abuse in mobile games while we have higher expectations for real games.
Just a rant there. It'll change if and when it changes I suppose.
Is the methanol price low due to supply and demand though? Ethanol is used for fuel and also is fun to drink. Methanol, as you said, is not used in cars and is super toxic. If we changed the first one, the price of methanol would probably go up, no?
You seem to assume that democracy automatically precludes tyranny. I see zero evidence from history of this being the case. In fact, I see quite the opposite: tyrants seem to reach their heights when people feel like they were given a choice to put him into power and he's on their side.
Anyway, people didn't vote FOR the NSA spying on them, and most americans don't vote in elections anyway. You could make a reasonable argument that they got what they asked for, that they should have seen the NSA spying coming based on their reactions to 9/11 and that not voting is saying "whatever." I'd agree with you on that, though I would disagree that being politically stupid means you DESERVE to have your rights eroded. But bottom line, no, the NSA programs were not democratically supported by the people in any meaningful sense of the phrase.
TLDR: It will probably be about a year to replicate it in humans. Therapy will be several years even assuming it's perfectly safe and assuming no political interference.
It's not a complete departure from previous stuff, though it looks like it is a new technique, so it will need to be independently replicated. Induced pluripotent stem cells took over a year to be reproduced, so there's that.
The next steps are longer, making sure it's safe, and finding a way to harness it.
Clinical trials for stem cell therapies are underway, but I'm not aware of anything so far that is a stunning success, where you put in stem cells and get a regenerated heart, liver, whatever, so we're not quite ready to hit the ground running. Of course, a lot of that was held back by the lack of stem cells which the host's immune system wouldn't reject, so theyr'e a lot closer now. Work on ESC or IPSC advanced being able to harness it, but I don't think there are any clear-cut treatments we know of that were simply waiting on a good source of cells. Spinal cord injuries in mice, I know they're not there yet, you inject cells you've directed somewhat to differentiate into neurons and the recovery rates in mice are nothing miraculous yet. They're improved, but there's the added complication that mice tend to recover from spinal cord injuries better than humans: they're a lot younger than us and can naturally recover better than we can. So it doesn't look like this immediately opens doors to treatments in humans, though it definitely speeds it up a lot. (And I could be wrong about there not being treatments ready to go in humans right now).
On safety, cancer is always an issue with pluripotent cells. Injecting pluripotent stem cells, which can make anything, makes teratomas, which are tumors of mixed cell populations. That's actually a test of stem cells: inject it into a mouse, if you get tumors that have several types of cells in them, you know you've actually got pluripotent stem cells. Teratomas can be complicated to treat though, so injecting pluripotent stem cells into a patient is a terrible idea.
Induced pluripotent stem cells have the additional hazard that you're explicitly turning on cancer-causing genes in the cells to make them that way. They appear to be turned back off, but it's still a concern. Furthermore, there have been suggestions that reverting cells back to a pluripotent state increases the likelihood of mutations. Obviously if the rate of mutation during the process is too high, that can also cause cancer. I haven't been following that literature, so I don't know if that's been discarded with IPSC. And I don't think it's been done with this new technique, though I haven't read the paper.
So there's no clear timeline, which is disappointing, but whatever the timing was going to be, it's shorter now, so yay.
I don't see how that changes things. He was collecting discarded trash from his neighbors, so he didn't enter into agreements there. Monsantos patents on glyphosphate are expired, so using round-up to enrich the trash doesn't change anything. Sneaky, maybe, but seeds blowing off your property are no longer yours.
I could see how selling the seed would get him into trouble with patents, but that's only reasonable if you accept that patents on living things are reasonable.
Well, now the intelligence services work for him. You don't say you currently work as a servant even if you used to be a servant yourself and currently use servants.
I'm guessing because either 1. He sees cable news and thinks we're so stupid we believe anything, not realizing we only believe anything if it comes from "real americans" or something like that, or 2. He can.
Hypocrisy and propaganda? Try ignorance: most of the people calling him traitor are too stupid to remember what was actually going on at the time. They just hear someone say he hurt the US and are bleating for his blood without understanding what happened. Is that better? Well, no...
Remember that reputation isn't an on/off switch. He's gained a lot of reputation with the NSA revelations. How much of that does "this could be useful to putin" reduce it? 1%?
Perhaps he thought it would start a debate. Does it reduce his reputation if he honestly thought he could start another change in his host country?
Boredom and isolation often leads to deviant behavior. How many of us got into nerd stuff because we were bored and wanted to know if we could "hack" something we weren't supposed to? I started reading 2600 before I got my drivers license. It was, fortunately, far over my head, and thanks to dialup, even if it weren't, that would be almost as boring as homework, so I never actually did anything.
I wonder what the solution is. My kid isn't going to have those limitations, even comcast is vastly superior to dialup, and he's getting a head start on using computers.
Maybe I'll have to stick with apple products, make sure he stays in the walled garden and out of the CRA website.
I think that could be valuable: if we start allowing street cops to use this to delete evidence of their pointlessly aggressive tactics, that's a GREAT sign to leave the country ASAP.
And tell me this... Where can you find daily national/world news with the same quality as the approx. 4am newscasts on CBS/NBC/ABC? BBC World Service looks like crap by comparison, though easily better than CNN/MSNBC/FauxNews of course.
If I'm up at 4AM, the TV guide channel is about the level of journalism I'm capable of appreciating.
Also, does the BBC website not work at 4AM? Because one could just browse that. What's so bad about the BBC world service? I'm asking honestly, I've never been a fan of video news, and never been a fan of anything that early in the morning.
The degree matters though. If it's worse than normal, it might be a good point. I doubt anyone has done a controlled study and quantified the effect, but just in theory it COULD be a reasonable statement.
No no no! You're totally selling it wrong! You've got to say it's building up! Lemme give you an example:
"Studies show that the CRACK BABIES OF THE 80'S are now having crack babies of their own who are EVEN WORSE and UNABLE TO PLAY WITH LEGOS AND INSTEAD HAVE EVIL HACKING SKILLS!!!"
See? Three offers of employment in my inbox from Huffington Post already!
I think it's pretty likely that people smart enough to make a space elevator will be smart enough to consider what happens when it goes wrong. Whether they will find it worthwhile to do anything about it is a different story, but it will be considered, that's for sure.
I'm always hearing about google being the target of Steve Jobs' ego-driven "thermonuclear war" with patents. What are some examples of google patent trolling as you've suggested? I'm not saying I think google is actually behaving unlike a corporation, just that I don't know of any examples of them doing what you're saying they're doing.
High profile murderers who make no attempt to conceal their crime usually do it more for attention. They might tell themselves it's for higher reasons, like they hate that politician or that race, but really it's that their egos aren't satisfied. Same with school shootings. They shoot up their schools because they want attention from their classmates. With columbine and other school shootings, we like to tell ourselves they're going rambo because they were bullied, and the shooters did too. We tell ourselves the lie because it's easier to think kids only do this when put under extreme pressure by bullying, we don't like to think that some kids are just psychopaths who are evil. They told themselves it was because of bullying because that sounds better than "We're bored and want attention."
Although early media reports attributed the shootings to a desire for revenge on the part of Harris and Klebold for bullying that they received, subsequent psychological analysis indicated Harris and Klebold harbored serious psychological problems. According to Dave Cullen, Harris, who conceived the attacks, was a "cold-blooded, predatory psychopath" and an intelligent, charming liar with "a preposterously grand superiority complex, a revulsion for authority and an excruciating need for control". In Cullen's assessment, Harris lacked remorse or empathy for others, and sought to punish them for their perceived inferiority.
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It's kind of funny sometimes. Like when EA did the humble bundle, essentially giving away medal of honor and some other games that were worth at least a dollar. I installed it, updated it, and later tried booting it up offline.
No go: the basically free game which was three years old needed an online connection, even for single player. You know, to make sure I donated at least a penny to the EFF for the game instead of just pirating it.
At least it sounds like they have an actual reason this time. They didn't used to bother explaining it. It was just
Apple: Here's your new phone, and you'll want to buy a new cord too.
Customer: Oh no thanks, I have the old one.
Apple: That one won't work anymore, the new one is $40!
Customer: Wait, why won't it work? It's exactly the same.
Apple: It's incompatible with the new phone.
Customer: It IS compatible! See, I can plug it in!.. and it's telling me it's not compatible?
Apple: Yes, because it's incompatible.
Customer: Why is it incompatible!?! It fits and carries electricity still!
Apple: Because when you plug it in, the phone tells you it's incompatible and stops itself from charging... duh...
Customer: This seems like you artificially made the phone incompatible with old cords just to nickle and dime me for new accessories!
Apple: No sir, it costs forty dollars, not fifteen cents.
There's no reasoning someone out of a position they didn't reason themselves into. Clearly, you want to believe that there is a crisis in education and parenting and are unable to consider anything that doesn't justify your position on the matter. So I give up, and I'll just say I'm glad you have limited control of education and parenting.
Forget moral compass, logical thought completely disappears. "Comcast did or said something, or something happened or was said to comcast: prepare for the internet to get slower and the bill to go up, and some assholes to blabber on about freedoms from government intrusion."
They already have.. We have the KKK to thank for that precedent, but it would have happened anyway with protests.
Of course, it's not always good idea to wear masks at protests anyway: agent provocateurs can easily infiltrate, start violence, and then give the police an excuse to shut it down. Needless to say, anti-mask laws don't apply to police.
No problem. I just have several friends who are teachers, both by profession and by calling. This is one of their favourite talking points after they get a few drinks into them. The friction is there, and it's definitely increasing.
That's still anecdotal evidence. Even if these friends of yours have been teaching for the last 30 years, that's still not very reliable unless they've found a way to quantify that it's getting worse.
Note that you yourself agree that number has tripled over just 40 years. I find it strange that you would consider that tripling of demand for certain services that require heavy investment and long term preparation will not generate friction between consumers of said services and providers.
Nonsense. The article said the proportion of mothers 35 or older has tripled in the past 40 years. That doesn't represent a tripling of demand from schools.
"Nowadays?" That and your unquantified charge that "schools used ter be about LEARNING, now they're about BABYSITTIN!" makes me think you're romanticizing the past.
Parents haven't changed that much. The percentage of women aged 35 or older having children increased from 5% in the 70's... to about 15% today. We're not talking about a fundamental change in society here. Schools have always been partly about taking the kids off parents' hands for a while. Nannies weren't invented anytime recently. Boarding schools are pretty rare these days.
I also really don't think there's evidence of "a large amount of friction in many countries" in relation to kids and parents compared to years past. Kids and parents of any age don't get along, but things turn out okay.
Without data to back up your claim that older parents are worse, I'd suggest the opposite hypothesis: that older parents have less of a struggle to support their children, have to spend less time at work to do so, and thus are better parents.
Lets not say the sky is falling, because it doesn't appear to be doing so and in general almost never does. I know it's fun to run around squawking that we're doomed, but citations are needed before I'll allow it to continue.
I'll get off your lawn now.
Predictions aren't facts no matter how certain you are of them, so "These are the facts" isn't really accurate. Aside from that I sadly can't disagree.
I'd say "it sucked" goes for almost all mobile games. Most non-mobile games aren't great, but the amount of shovelware seems much lower on consoles and PC.
When is "mobile game" going to mean more than shitty controls and everything else? The best games at best seem to be "good" only when judged by the standard of "compared to what else I could be doing on a plane."
Even with handheld game systems with decent controls, like the DS, there were few games that I'd choose to play if I could be playing on a PC or console. I personally don't believe that more computing power will inevitably make console or PC games better, I think it's just a problem of lower expectations for mobile games. We're used to 99.9% of mobile games being shit. Compare the amount of shit EA got for Sim city 5 vs the iOS dungeon keeper. About the same level of complaints from what I could see, but the two games didn't seem to be the same level of shitty. Sim City 5 had some technical problems. Dungeon keeper was fundamentally some asshole asking you for change over and over again. EA deserves much more shit for dungeon keeper, but we're used to abuse in mobile games while we have higher expectations for real games.
Just a rant there. It'll change if and when it changes I suppose.
Is the methanol price low due to supply and demand though? Ethanol is used for fuel and also is fun to drink. Methanol, as you said, is not used in cars and is super toxic. If we changed the first one, the price of methanol would probably go up, no?
You seem to assume that democracy automatically precludes tyranny. I see zero evidence from history of this being the case. In fact, I see quite the opposite: tyrants seem to reach their heights when people feel like they were given a choice to put him into power and he's on their side.
Anyway, people didn't vote FOR the NSA spying on them, and most americans don't vote in elections anyway. You could make a reasonable argument that they got what they asked for, that they should have seen the NSA spying coming based on their reactions to 9/11 and that not voting is saying "whatever." I'd agree with you on that, though I would disagree that being politically stupid means you DESERVE to have your rights eroded. But bottom line, no, the NSA programs were not democratically supported by the people in any meaningful sense of the phrase.
TLDR: It will probably be about a year to replicate it in humans. Therapy will be several years even assuming it's perfectly safe and assuming no political interference.
It's not a complete departure from previous stuff, though it looks like it is a new technique, so it will need to be independently replicated. Induced pluripotent stem cells took over a year to be reproduced, so there's that.
The next steps are longer, making sure it's safe, and finding a way to harness it.
Clinical trials for stem cell therapies are underway, but I'm not aware of anything so far that is a stunning success, where you put in stem cells and get a regenerated heart, liver, whatever, so we're not quite ready to hit the ground running. Of course, a lot of that was held back by the lack of stem cells which the host's immune system wouldn't reject, so theyr'e a lot closer now. Work on ESC or IPSC advanced being able to harness it, but I don't think there are any clear-cut treatments we know of that were simply waiting on a good source of cells. Spinal cord injuries in mice, I know they're not there yet, you inject cells you've directed somewhat to differentiate into neurons and the recovery rates in mice are nothing miraculous yet. They're improved, but there's the added complication that mice tend to recover from spinal cord injuries better than humans: they're a lot younger than us and can naturally recover better than we can. So it doesn't look like this immediately opens doors to treatments in humans, though it definitely speeds it up a lot. (And I could be wrong about there not being treatments ready to go in humans right now).
On safety, cancer is always an issue with pluripotent cells. Injecting pluripotent stem cells, which can make anything, makes teratomas, which are tumors of mixed cell populations. That's actually a test of stem cells: inject it into a mouse, if you get tumors that have several types of cells in them, you know you've actually got pluripotent stem cells. Teratomas can be complicated to treat though, so injecting pluripotent stem cells into a patient is a terrible idea.
Induced pluripotent stem cells have the additional hazard that you're explicitly turning on cancer-causing genes in the cells to make them that way. They appear to be turned back off, but it's still a concern. Furthermore, there have been suggestions that reverting cells back to a pluripotent state increases the likelihood of mutations. Obviously if the rate of mutation during the process is too high, that can also cause cancer. I haven't been following that literature, so I don't know if that's been discarded with IPSC. And I don't think it's been done with this new technique, though I haven't read the paper.
So there's no clear timeline, which is disappointing, but whatever the timing was going to be, it's shorter now, so yay.
I don't see how that changes things. He was collecting discarded trash from his neighbors, so he didn't enter into agreements there. Monsantos patents on glyphosphate are expired, so using round-up to enrich the trash doesn't change anything. Sneaky, maybe, but seeds blowing off your property are no longer yours.
I could see how selling the seed would get him into trouble with patents, but that's only reasonable if you accept that patents on living things are reasonable.
Well, now the intelligence services work for him. You don't say you currently work as a servant even if you used to be a servant yourself and currently use servants.
I'm guessing because either 1. He sees cable news and thinks we're so stupid we believe anything, not realizing we only believe anything if it comes from "real americans" or something like that, or 2. He can.
Hypocrisy and propaganda? Try ignorance: most of the people calling him traitor are too stupid to remember what was actually going on at the time. They just hear someone say he hurt the US and are bleating for his blood without understanding what happened. Is that better? Well, no...
Remember that reputation isn't an on/off switch. He's gained a lot of reputation with the NSA revelations. How much of that does "this could be useful to putin" reduce it? 1%?
Perhaps he thought it would start a debate. Does it reduce his reputation if he honestly thought he could start another change in his host country?
Boredom and isolation often leads to deviant behavior. How many of us got into nerd stuff because we were bored and wanted to know if we could "hack" something we weren't supposed to? I started reading 2600 before I got my drivers license. It was, fortunately, far over my head, and thanks to dialup, even if it weren't, that would be almost as boring as homework, so I never actually did anything.
I wonder what the solution is. My kid isn't going to have those limitations, even comcast is vastly superior to dialup, and he's getting a head start on using computers.
Maybe I'll have to stick with apple products, make sure he stays in the walled garden and out of the CRA website.
I think that could be valuable: if we start allowing street cops to use this to delete evidence of their pointlessly aggressive tactics, that's a GREAT sign to leave the country ASAP.
And tell me this... Where can you find daily national/world news with the same quality as the approx. 4am newscasts on CBS/NBC/ABC? BBC World Service looks like crap by comparison, though easily better than CNN/MSNBC/FauxNews of course.
If I'm up at 4AM, the TV guide channel is about the level of journalism I'm capable of appreciating.
Also, does the BBC website not work at 4AM? Because one could just browse that. What's so bad about the BBC world service? I'm asking honestly, I've never been a fan of video news, and never been a fan of anything that early in the morning.
The degree matters though. If it's worse than normal, it might be a good point. I doubt anyone has done a controlled study and quantified the effect, but just in theory it COULD be a reasonable statement.
No no no! You're totally selling it wrong! You've got to say it's building up! Lemme give you an example:
"Studies show that the CRACK BABIES OF THE 80'S are now having crack babies of their own who are EVEN WORSE and UNABLE TO PLAY WITH LEGOS AND INSTEAD HAVE EVIL HACKING SKILLS!!!"
See? Three offers of employment in my inbox from Huffington Post already!
I think it's pretty likely that people smart enough to make a space elevator will be smart enough to consider what happens when it goes wrong. Whether they will find it worthwhile to do anything about it is a different story, but it will be considered, that's for sure.
I'm always hearing about google being the target of Steve Jobs' ego-driven "thermonuclear war" with patents. What are some examples of google patent trolling as you've suggested? I'm not saying I think google is actually behaving unlike a corporation, just that I don't know of any examples of them doing what you're saying they're doing.
Although early media reports attributed the shootings to a desire for revenge on the part of Harris and Klebold for bullying that they received, subsequent psychological analysis indicated Harris and Klebold harbored serious psychological problems. According to Dave Cullen, Harris, who conceived the attacks, was a "cold-blooded, predatory psychopath" and an intelligent, charming liar with "a preposterously grand superiority complex, a revulsion for authority and an excruciating need for control". In Cullen's assessment, Harris lacked remorse or empathy for others, and sought to punish them for their perceived inferiority.
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