Here are couple of related patent numbers I found, doing a quick search at IBM's Patent site; search for "Time Domain" and "Fullerton; Larry W." as the Inventors & Companies, look at referenced patents:
US5687169: Full duplex ultrawide-band communication system and method - Earliest "Time Domain" result
US4641317: Spread spectrum radio transmission system - Earliest "Fullerton; Larry W." result.
There are a good 40 patents referencing the older, USP4641317, originally filed on Dec 3, 1984.
...I wonder what a prior art search would turn up.?. As the saying goes, a rose by any other name, is still a rose.
Bare in mind that if you don't buy the multi-proc with a full complement of processors, it could be that much harder for you to fill the empty slots further down the line.
I'm already running into this problem with my dual-capable P2-266. I bought it with a single processor, but now that I'm thinking of adding a second, I'm having to hunt for just the right twin/match.
Would resonance be affected? Most likely. Like an antenna, I would expect a base-pair (v.s. individual bases) to be "de-tuned" by their close/attached proximity. A difference in behaviour should manifest itself as some sort of "polar" RF signature for the pair.
Analogy time:
Think of it as a magnet with four possible orientations. You're looking at the difference between N-S, W-E, E-W and S-N orientations with an unmarked (no N/S/E/W markings) compass. You can determine the orientation of one magnet relative to another by watching and recording the relative changes on the compass when you bring it near each. Compare that to a set of known samples, and the actual orientations fall out of the measurements.
eg. You measure: abd-cdd-aba. You then bring calibrate your compass with some known samples and discover that a=NS, b=EW, c=SN, d=WE. From your measurements, you get: (NS)(EW)(WE)-(SN)(WE)(WE)-(NS)(EW)(NS)
Grossly over-simplified, but hopefully a little more clear.:-) If the two types of base-pairs have "sufficiently different" signatures, the task is easier because it's like being able to automatically distinguish between a N-S/S-N magnet and a W-E/E-W magnet by their shape.
eg. You already know that (a,c) forms a pair of measurements and (b,d) forms another pair. Calibrate to differentiate between a and c, and between b and d.
The complementary nature of the bases should actually work in your favour. My proposal/idea does depend on uniquely identifiable RF signatures for each base, relative to the other three. If this is the case, you apply each signature in sequence and watch/scan for the resonance. The existance of one pair over the other would strengthen that pair of RF signatures; orientation would show up via the scanning action, maybe some phase variation/difference.
I would expect the hydrogen bonding interference to be relatively easy to filter out; treat it as (average) background noise and filter with a little signal processing. You would have four sets of data (one per base) to work with, making it that much easier. Apply some sort of "helix transform" to account for differences in base-pair oriention from one to the next...
I guess we'll just have to wait and see!:-)
(caveat: my background is in electrical engineering, semiconductors and mathematics, not biology and chemistry, so apply holes in my logic as you see fit.)
I wonder if the strands could be "read" by electrical means.?. After all, DNA is ultimately a biologically evolved four-state memory device.
One method: If each base has a unique resonant frequency (or set of frequencies, like little tiny antennas - akin to spectroscopy), and you "modulate" a strand at each resonance set, would you be able to extract an RF profile or "image" of the strand's sequence? Scanning Capacitance Microscopes might do the trick.
Or if you want a device that's removeable and electrically IDE compatible, go with SanDisk's CompactFlash... (doesn't have to be SanDisk; other companies manufacture them) I think they're up to 96MB/card densities now.
The other nice thing about CF is the digital camera generated demand; more market to drive mass-production and lower costs.
Enough molehills and the mountain is but a shadow.
on
JWZ isn't the only one
·
· Score: 1
I wouldn't downplay the effect those layoffs will have, not just yet.
People are going to be feeling very insecure for the next while, revising their resumes and following up head-hunter calls, just in case...
AOL's not going to be able to stop the bleeding that quickly; it's great time for a career change in this business.
JWZ's second-last paragraph, first sentence, just about sums it up: "I must say, though, that it feels good to be resigning from AOL instead of resigning from Netscape."
It's a simple substitution of every instance of the word "Internet" with the word "Telephone". Not completely grammatically accurate, but you get the idea.
...a little food for thought...
perl: s/Internet/Telephone/g;
Rape. It's a violent crime, arguably the most violent crime, even more savage than murder. The psychological repercussions are severe to the victim, causing even years of trauma. It's frighteningly common--and it's often associated with the Telephone. We've all heard the story in which a fourteen year old girl living in Maine is given a plane ticket to Arizona by a forty-seven year old man claiming to be a eighteen year old boy in an America On-line chatroom. She accepts--heck, she's in love and her parents are a pain--and flies to meet him. Of course, upon seeing him, she knows he's not the eighteen year old stud she'd fantasized about, but being alone and lost in a foreign city leaves her with no obvious choice but to leave the airport with him. Of course, he takes her to the local motor lodge and rapes her.
Unfortunately, the media loves these stories, the more horrible the better. It's the media that establishes ideas in people, but I did not realize strength of the current attitudes about Telephone users until a friend of mine was raped by someone from the Big Bad Telephone. After the rape, which had taken place in her house, she went to her local hospital, where she was tested for sexually transmitted diseases, and her physical wounds treated. The rapist remained in her house, and she was advised to call the police. The police escorted the rapist off her property, and persuaded her to press charges, claiming she had a rock solid case. To this, she consented.
Apparently, the detective in charge on her case didn't agree that the case was closed when he learned she had met the rapist on the Telephone. "They [Telephone users] are nothing but relentless sex addicts," he told her. "Furthermore, every conversation on the Telephone is logged. I can get access to these logs, and if I find that you ever hugged him on the Telephone, I will show that this is not a matter of rape, but consentual sex." He proceeded to ask if she had met others from the Telephone, which she had. Upon finding out that she had met me on numerous occasions, and even had sex with me, the "slueth" felt satisfied he had proved his point, "No one on the Telephone ever wants to do anything but have sex."
Despite the fact that my friend was injured to the point that, according the documented hospital report, she had bruises and tears in her vagina, and the fact that people willingly having sex usually do not injure one another, the police threatened my friend with the possibility of putting her in jail if she was lying!
It is ludicrous to believe that all people associated with the Telephone are sex-crazed maniacs, or that meeting someone in real-life is recipe for disaster. I've met a great deal of people from the Telephone, for both personal and professional reasons, and I've yet to be raped. Yes, like a few of my real-life friends and relationships, I even slept with a few people I met from the Telephone. I even spent a week with one Telephone pal snowed-in together during the blizzard that hit the midwestern United States this past January.
Was I concerned about my safety at any of these times I met someone from the Telephone? No, I wasn't--no more than I would be meeting someone I didn't know very well in person for dinner and possibly spending the night together. I've never met someone from the Telephone expecting sex, and while I'm sure there are many that do, I would hazard a guess that the number that do is not any higher than people who know each other in real-life would in a similar situation (e.g., sharing a hotel room in a town).
I once met, with the permission of her mother, a girl in high school, since I happened to be traveling through her town and had some extra hours to spare for dinner. She later mentioned that a real-life friend of hers admonished her for meeting me, claiming she hardly knows me. Well, how much do two people know each other on a first date for coffee or dinner? Interestingly, the media refuses to acknowledge this similarity.
It's important to be careful when meeting someone from the Telephone--just as it's normal to be careful in any situation where you've not spent a large amount of time together in person. It's important to realize that a person's remarks and responses in a chatroom or a MUD may be contrived, no matter how fluent they seem to flow. Likewise, there are plenty of phony men and women in every community, and you're just as likely to encounter them in real-life, rapists or not. Regardless, it is certainly not in the interests of society for those who enforce the law to ridicule rape, no matter the circumstances of how the involved individuals initially came in contact with each other. Rape is rape; it's a matter far too serious for qualification.
I know I waste more paper printing "backup" copies of my documents than any paper forms I fill out; I've lost too many documents to system instability and file corruption than I care to remember.
Thank goodness there's a Windoze version of Vim and plenty of Linux workstations I can telnet into for any coding endeavours...
What happened to Katz' book sounds a lot like the peer-review method behind the success of Linux et al.
We know Katz from his ramblings, we know his style. We don't necessarily agree with everything he writes, but he holds his own when we hold him accountable to his words.
So, when he posted the excerpt, we reviewed it ourselves with that same peer-review method in mind. It's an ongoing dialog, not a static piece of text.
Beats a second-hand magazine/newspaper review any day, in my books.:-)
I'd counter that sentence with a little annecdotal evidence. (That sentence bothered me too)
Once, if I wanted to install a new device+driver, I had to compile it into the kernel (=bloat). Now all I have too do is load the driver-module (=counter-bloat), as is done in RH.
I can still compile the features into the kernel if I want to, but I don't have to. The driver can be modified, recompiled and integrated in future developments; the hardware hasn't been rendered unusable.
Sure, the modular version is going to be "bloated" because of the interface overhead, but at least it's not static.
I guess what I'm getting at is, there is a BIG difference between closed-source (static) bloat and open-source (dynamic) bloat. Change. Also, cost rises exponentially if you can't understand the code; opensource encourages readability. Scarce talent today != scarce talent tomorrow.
And last, but certainly not least, Linux+GNU has a secret weapon. You know all those old/used computers that have been and are being shipped to developing nations? Which software+tools do you think they'll learn, use, and develop.?.:-)
Now, if this thing will work on a dual-processor machine with a dual-headed video card - i.e. one proc + one head per OS - then I'll definitely be interested...
Here are couple of related patent numbers I found, doing a quick search at IBM's Patent site; search for "Time Domain" and "Fullerton; Larry W." as the Inventors & Companies, look at referenced patents:
There are a good 40 patents referencing the older, USP4641317, originally filed on Dec 3, 1984.
...I wonder what a prior art search would turn up.?. As the saying goes, a rose by any other name, is still a rose.
Anyhow, just a little FYI. Enjoy!
Looks like 3dfx cards are to video what winmodems are to communications. Not an option.
:-)
(OpenGL rules!
Bare in mind that if you don't buy the multi-proc with a full complement of processors, it could be that much harder for you to fill the empty slots further down the line.
I'm already running into this problem with my dual-capable P2-266. I bought it with a single processor, but now that I'm thinking of adding a second, I'm having to hunt for just the right twin/match.
Right now when I scan down all the posts in here, although there are plenty of replies all I "see" is a mass of posts from this Bruce Perens guy. :-)
Completely skews the way the comments read; self moderation would be a good thing.
Would resonance be affected? Most likely. Like an antenna, I would expect a base-pair (v.s. individual bases) to be "de-tuned" by their close/attached proximity. A difference in behaviour should manifest itself as some sort of "polar" RF signature for the pair.
:-) If the two types of base-pairs have "sufficiently different" signatures, the task is easier because it's like being able to automatically distinguish between a N-S/S-N magnet and a W-E/E-W magnet by their shape.
Analogy time:
Think of it as a magnet with four possible orientations. You're looking at the difference between N-S, W-E, E-W and S-N orientations with an unmarked (no N/S/E/W markings) compass. You can determine the orientation of one magnet relative to another by watching and recording the relative changes on the compass when you bring it near each. Compare that to a set of known samples, and the actual orientations fall out of the measurements.
eg. You measure: abd-cdd-aba. You then bring calibrate your compass with some known samples and discover that a=NS, b=EW, c=SN, d=WE. From your measurements, you get: (NS)(EW)(WE)-(SN)(WE)(WE)-(NS)(EW)(NS)
Grossly over-simplified, but hopefully a little more clear.
eg. You already know that (a,c) forms a pair of measurements and (b,d) forms another pair. Calibrate to differentiate between a and c, and between b and d.
Plenty of research potential, eh?
The complementary nature of the bases should actually work in your favour. My proposal/idea does depend on uniquely identifiable RF signatures for each base, relative to the other three. If this is the case, you apply each signature in sequence and watch/scan for the resonance. The existance of one pair over the other would strengthen that pair of RF signatures; orientation would show up via the scanning action, maybe some phase variation/difference.
:-)
I would expect the hydrogen bonding interference to be relatively easy to filter out; treat it as (average) background noise and filter with a little signal processing. You would have four sets of data (one per base) to work with, making it that much easier. Apply some sort of "helix transform" to account for differences in base-pair oriention from one to the next...
I guess we'll just have to wait and see!
(caveat: my background is in electrical engineering, semiconductors and mathematics, not biology and chemistry, so apply holes in my logic as you see fit.)
I wonder if the strands could be "read" by electrical means.?. After all, DNA is ultimately a biologically evolved four-state memory device.
One method: If each base has a unique resonant frequency (or set of frequencies, like little tiny antennas - akin to spectroscopy), and you "modulate" a strand at each resonance set, would you be able to extract an RF profile or "image" of the strand's sequence? Scanning Capacitance Microscopes might do the trick.
Just a thought...
Or if you want a device that's removeable and electrically IDE compatible, go with SanDisk's CompactFlash... (doesn't have to be SanDisk; other companies manufacture them) I think they're up to 96MB/card densities now.
The other nice thing about CF is the digital camera generated demand; more market to drive mass-production and lower costs.
I wouldn't downplay the effect those layoffs will have, not just yet.
People are going to be feeling very insecure for the next while, revising their resumes and following up head-hunter calls, just in case...
AOL's not going to be able to stop the bleeding that quickly; it's great time for a career change in this business.
JWZ's second-last paragraph, first sentence, just about sums it up: "I must say, though, that it feels good to be resigning from AOL instead of resigning from Netscape."
Dr. Who's companion, K-9.
It's a simple substitution of every instance of the word "Internet" with the word "Telephone". Not completely grammatically accurate, but you get the idea.
...a little food for thought...
perl: s/Internet/Telephone/g;
Rape. It's a violent crime, arguably the most violent crime, even more savage than murder. The psychological repercussions are severe to the victim, causing even years of trauma. It's frighteningly common--and it's often associated
with the Telephone. We've all heard the story in which a fourteen year old girl living in Maine is given a plane ticket to Arizona by a forty-seven year old man claiming to be a eighteen year old boy in an America On-line chatroom. She accepts--heck, she's in love and her parents are a pain--and flies to meet him. Of course, upon seeing him, she knows he's not the eighteen year old stud she'd fantasized about, but being alone and lost in a foreign city leaves her with no obvious choice but to leave the airport with him. Of course, he takes her to the local motor lodge and rapes her.
Unfortunately, the media loves these stories, the more horrible the better. It's the media that establishes ideas in people, but I did not realize strength of the current attitudes about Telephone users until a friend of mine was raped by someone from the Big Bad Telephone. After the rape, which had taken place in her house, she went to her local hospital, where she was
tested for sexually transmitted diseases, and her physical wounds treated. The rapist remained in her house, and she was advised to call the police. The police escorted the rapist off her property, and persuaded her to press charges, claiming she had a rock solid case. To this, she consented.
Apparently, the detective in charge on her case didn't agree that the case was closed when he learned she had met the rapist on the Telephone. "They [Telephone users] are nothing but relentless sex addicts," he told her. "Furthermore, every conversation on the Telephone is logged. I can get access to these logs, and if I find that you ever hugged him on the Telephone,
I will show that this is not a matter of rape, but consentual sex." He proceeded to ask if she had met others from the Telephone, which she had. Upon finding out that she had met me on numerous occasions, and even had sex with me, the "slueth" felt satisfied he had proved his point, "No one on the Telephone ever wants to do anything but have sex."
Despite the fact that my friend was injured to the point that, according the documented hospital report, she had bruises and tears in her vagina, and the fact that people willingly having sex usually do not injure one another, the police threatened my friend with the possibility of putting her in jail if she was lying!
It is ludicrous to believe that all people associated with the Telephone are sex-crazed maniacs, or that meeting someone in real-life is recipe for disaster. I've met a great deal of people from the Telephone, for both personal and professional reasons, and I've yet to be raped. Yes, like a few of my real-life friends and relationships, I even slept with a few people I met from the Telephone. I even spent a week with one Telephone pal snowed-in together during the blizzard that hit the midwestern United States this past January.
Was I concerned about my safety at any of these times I met someone from the Telephone? No, I wasn't--no more than I would be meeting someone I didn't know very well in person for dinner and possibly spending the night together. I've never met someone from the Telephone expecting sex, and while I'm sure there are many that do, I would hazard a guess that the number that do is not any higher than people who know each other in real-life would in a similar situation (e.g.,
sharing a hotel room in a town).
I once met, with the permission of her mother, a girl in high school, since I happened to be traveling through her town and had some extra hours to spare for dinner. She later mentioned that a real-life friend of hers admonished her for meeting me, claiming she hardly knows me. Well, how much do two people know each other on a first date for coffee or dinner? Interestingly, the media refuses to acknowledge this similarity.
It's important to be careful when meeting someone from the Telephone--just as it's normal to be careful in any situation where you've not spent a large amount of time together in person. It's important to realize that a person's remarks and responses in a chatroom or a MUD may be contrived, no matter how fluent they seem to flow. Likewise, there are plenty of phony
men and women in every community, and you're just as likely to encounter them in real-life, rapists or not. Regardless, it is certainly not in the interests of society for those who enforce the law to ridicule rape, no matter the circumstances of how the involved individuals initially came in contact with each other. Rape is rape; it's a matter far too serious for qualification.
Can't help but laugh at the paperless goals.
I know I waste more paper printing "backup" copies of my documents than any paper forms I fill out; I've lost too many documents to system instability and file corruption than I care to remember.
Thank goodness there's a Windoze version of Vim and plenty of Linux workstations I can telnet into for any coding endeavours...
...I'm still partial to the MicroOptical solution. Less intrusive.
BTW, Colorado MicroDisplay is at http://www.comicro.com/index.html.
The Virtual Vision subsidiary is at http://www.virtualvision.com/
...probably because, they demoed the e-Mate version (article mentions it) just over a year ago.
Gotta love that. Thought this database thing was for CD info, not graphic display.
I guess this means I always have to have a GUI running to access their CDDB. Yeah, right!
So, what's next? Ultrasonic bathtubs? :-)
What happened to Katz' book sounds a lot like the peer-review method behind the success of Linux et al.
:-)
We know Katz from his ramblings, we know his style. We don't necessarily agree with everything he writes, but he holds his own when we hold him accountable to his words.
So, when he posted the excerpt, we reviewed it ourselves with that same peer-review method in mind. It's an ongoing dialog, not a static piece of text.
Beats a second-hand magazine/newspaper review any day, in my books.
I'd counter that sentence with a little annecdotal evidence. (That sentence bothered me too)
:-)
Once, if I wanted to install a new device+driver, I had to compile it into the kernel (=bloat). Now all I have too do is load the driver-module (=counter-bloat), as is done in RH.
I can still compile the features into the kernel if I want to, but I don't have to. The driver can be modified, recompiled and integrated in future developments; the hardware hasn't been rendered unusable.
Sure, the modular version is going to be "bloated" because of the interface overhead, but at least it's not static.
I guess what I'm getting at is, there is a BIG difference between closed-source (static) bloat and open-source (dynamic) bloat. Change.
Also, cost rises exponentially if you can't understand the code; opensource encourages readability. Scarce talent today != scarce talent tomorrow.
And last, but certainly not least, Linux+GNU has a secret weapon. You know all those old/used computers that have been and are being shipped to developing nations? Which software+tools do you think they'll learn, use, and develop.?.
Now, if this thing will work on a dual-processor machine with a dual-headed video card - i.e. one proc + one head per OS - then I'll definitely be interested...
Have to keep an eye on this one.