Breathing pure oxygen will NOT kill you..It's the concentration that will do the oxidative damage to your lungs. The Apollo astronauts (I believe) breathed pure oxygen, but at a very low pressure - 120 mm Hg which is close to the partial pressure of O2 that we breathe. Many patients in intensive care units breathe 100% O2 - but its a race to see if they get better before the O2 starts to irrtate their lungs
This problem seems like it would be a prime candidate for a DNA computer to solve. It would have made a nice race to see which technology could have arrived at the answer first.
If you read the article it explains how it was done. They used a screen in front of the display to generate images that are slightly angled to each eye. Unfortunately you must be a fixed distance from the screen in order for it to work. Link to how it works
I'm a resident in orthopaedic surgery - I typically put in 100+ hours/week. I've hit 130+ a couple times during the busy trauma season (Sping and Summer).. Crap I wish I didn't have to work so much, but oh well...people get screwed up.
Some Real Numbers...Here they are
on
RNA Computer
·
· Score: 1
Let's first calculate the # of permutations possible for an RNA string We have 4 bases (A,C,G and U (this is RNA not DNA right?)) - so we have 4 posibilities for a string of 1 bases, and 16 for a string of 2 bases (4x4=16 or written out AA,AC,AG,AU, CA,CC,CG,CU,etc). So for a string of 10 bnucleotide bases we have 4^10 possibilities or 1048576 (1x10^6). Thats alot for just such a short chain.
How much would that weigh? An average nucleotide (the base (ACGT or U) plus the binding sugar) has an atomic weight of approximately 500 Daltons. So if we multiply out the atomic weight times the number of strands divided by Avrogadros number (6.023x10^23) we can figure out the weight of those million different strings of RNA
So we get 500 x (1x10^6)/(6.023x10^23)= approx 1x10^-15 grams. THAT's 10to the MINUS 15 grams of material. That's a freakin TINY amount of stuff.
So how many solution could be in a gram(that's actually a fair amt of RNA,but anyway) 1x10^6 times 1x10^15 or 1x10^21 HUGE BRUTE numbers eh?
This isn't exactly right because you would have to make the RNA chain slightly longer (23 or 24 bases long) to get all of these solutions, but you get the point.
Of course an RNA or DNA computer won't be exactly correct. Binding mismatches can occur, you won't get truely random sequences or not all of them will form, but it will probably be MORE accurate than an electrical computer.
There are 3 issues here 1 They used another sheeps egg and implanted nuclear material into that egg. The host egg has it's own mitochondrial DNA and NOT Dollys'. There is a fair amount a variability in mitochondrial DNA which can and will lead to functional differences of the cells.
2 They used cells from Dolly that were already "aged" in her body. Cells have spacer sections (end caps is probably a better representative) on the ends of each chromosome called TELOMERES. They are long repetative segments that shorten with every subsequent division of the cell. They probably serve as some time keeper to prevent the cells from living too long and mutating to much (i.e. cancer prevention). Dolly is aging prematurely probably as a result of this. 3 - The implanted cell that they used has had it's own mutational events different from all of the rest of the cells in the body. An analogy would be to look at your skinn. Superficially it looks the same everywhere on your body, but up close you can see that it's different everywhere. Imagine your elbow skin on your face - looks different eh?
Undoubtably they would look very much like you. However environmental factors do play a role in determining how people look - they might be fatter/skinnier/shorter, etc. If you look at identicle twins you'll notice that they don't look exactly the same, yet they are essentially clones of eachother. The clonew will be close, but won't look exactly like you.
He could alweays pull a Ronald Reagan (during the Iran-Contra trials) and just claim that he has forgoten the key. I doubt the gov will ever crack it soon unless they do something like the distibuted net stuff. I'm not sure if they want to spend tha much money on this guy either and crucify him now that he is becoming a "cause celebrite" (where's the damn French accent keys?).
I had one once and it hurt like a sun-ova-biyatch That's why this would be beneficial....Plus the little kiddies would like i if it were truely painless
It's hard to reply to this statement since you are pretty much in the dark about immunology. The common cold and every other virus is able to mutate like a mofo and they do it constantly. I'm sure that the common cold and a bunch of other viruses will still be able to infect us. Bacterial and fungal inf ections would also not be affected by this drug and would still present challenges to our immune systems. So the bottom line is don't woory.
Pleconaril is the generic name for the medicine, e.g. the chemical name for the compound. When the drug company markets the drug, they give it a catchy REMEMBERABLE name like Virukil or something else that the PR dept thought of. That way the Docs and patients have an easier time remembering that company name for the drug and not some others company's name for it when it goes off patent. I know that most MDs usually refer to the drugs by their trade names (company names). Pfizer Pharm had trade-marked the name Viagra many years ago and were just waiting for the right drug to give the name to.
Actually what the nun study showed was that they suffered less of the typical effects of senility . They would still be suseptible to Alzheimers which is a disease process by which an abnormal protease (a protein that digests or cuts another protein) leaves waste snipets of protein outside the cell producing the characteristic Alzheimer plaques. This disease is unaffected by how much you "exercise your brain". Amgen and Harvard researchers published the discovery of the Alzheimer protease this week in Science - follow this link for synopsis
Actually what the nun study showed was that they suffered less of the typical effects of senility . They would still be suseptible to Alzheimers which is a disease process by which an abnormal protease (a protein that digests or cuts another protein) leaves waste snipets of protein outside the cell producing the characteristic Alzheimer plaques. This disease is unaffected by how much you "exercise your brain". Amgen and Harvard researchers published the discovery of the Alzheimer protease this week in Science - follow this link for synopsis
If one looks at the article - it mentions THOUSANDS of new cells migrating in the monkey brains. If I recall basic pathology correctly, the human brain has on the order of TRILLIONS of cells. No mention is made of whether any functional improvement or difference was noted and the article even mention that no one knows what the new neurons were doing. Chimps differ from we humans by approx a 1000 genes out of 100,000 or so and their brains are maybe a 1/3 of our size in the higher areas. It is reasonable to infer that if this magnitude of repair or growth occured in humans then not much of an appreciable difference would occur. Much of the (re)learning that occurs in traumatic brain injured patients(people and monkeys) involves new neural CONNECTIONS between cells - not the new growth of cells. Other physiologic processess are also occuring in the body which may play a role in the hinderence of developing new neurons. A child can fluently learn multiple languages easily, yet an adult will with difficultly learn one or two with an accent. An infants or childs brain is still growing and has not had its developmental proceses shut down by the effects of maturation hormones. Future research will probably concentrate on whether the adult brain cells are at the end of their lifetime or if they can be induced to be young again and divide and produce new neurons.
Not everyone likes the way Cindy Crawford or Richard Gere looks like. What if we eliminate some things such as shortness or depression - who will be the jockeys or blues musicians? Eliminate a gene for laziness and who will invent the next washing machine or remote control? I personally have a deaf/retarded aunt and I know that much of my compassion, patience and caring have come from her influence. It will be a difficult societal choice to say yes it's okay to correct this gene for dwarfism but not for pimples. At what point do we stop and let nature take its course - nature and evolution has done a fine job of making us who we are.
a chiropractor is basically gives massages - don't expect them to correct a real problem like CTS.
As far as rubber bands go - whatever...
If you really have CTS, then you'll have a positive electromyelogram (EMG) - it's a test where a physical medicine doctor (MD) will insert electrode into your muscles and nerves in your have to look for nerve conduction changes. CTS produce a real decrease in neerve conduction velocity and a few other things. Usually a scrupulous surgeon (Orthopedic or plastic) will only operate if you have a positive EMG since the surgery will in this case decompress the nerve. If you have a NEG EMG, then the surgeon won't operate since you prob don't have CTS and the CTS release surgery will not provide relief.
nuff said. look at the first anonymous coward reply under the first post for sigs and symptoms of the disease. The surgery Usually provides erlief - but nothing is an absolute in medicine - too many variables - we only play the percentages.
I've tried DL'ing the 6.1version from several sources and they all seem to crash, so I would hold off a bit before DL'ing the files. I did briefly use the 6.1 Beta and it ran very smoothly (and fast), but the non-beta is still buggy - I can't install it - it just crashes even before I can select which packages I want to install
I'm a surgical resident - I can't tell you how useful this little tool is for saving patient data, operative logs, important phone, pager #'s , antibiotic data and all sorts of other crap - like when my cases are scheduled. Basically 85% of the residents in my program have one of these because of those reasons and because it keeps our lab coats from overflowing with paper junk. Plus I can sit and play a game or take care of some other stuff when I'm waiting for anesthesia to finish putting the pt. under.
You assume that someone who suffers a moral deficit and hacks a non-offensive site would act in a benevolent manner and give directions on how to fix the security flaw. Such people are more likely not to act in that manner as proven by their previous actions. It is also possible for them to screw up and delete something important unknowlingly. If they want to hack, go have a hacker war and hack other hacker sites.
The whole brain is used, just not all of the neurons are firing at once. When they do all fire at once it's called an epileptic seizure which is generally regarded as BAD.
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Breathing pure oxygen will NOT kill you..It's the concentration that will do the oxidative damage to your lungs. The Apollo astronauts (I believe) breathed pure oxygen, but at a very low pressure - 120 mm Hg which is close to the partial pressure of O2 that we breathe. Many patients in intensive care units breathe 100% O2 - but its a race to see if they get better before the O2 starts to irrtate their lungs
This problem seems like it would be a prime candidate for a DNA computer to solve. It would have made a nice race to see which technology could have arrived at the answer first.
If you read the article it explains how it was done. They used a screen in front of the display to generate images that are slightly angled to each eye. Unfortunately you must be a fixed distance from the screen in order for it to work.
Link to how it works
I'm a resident in orthopaedic surgery - I typically put in 100+ hours /week. I've hit 130+ a couple times during the busy trauma season (Sping and Summer).. Crap I wish I didn't have to work so much, but oh well...people get screwed up.
Let's first calculate the # of permutations possible for an RNA string
We have 4 bases (A,C,G and U (this is RNA not DNA right?)) - so we have 4 posibilities for a string of 1 bases, and 16 for a string of 2 bases (4x4=16 or written out AA,AC,AG,AU, CA,CC,CG,CU,etc). So for a string of 10 bnucleotide bases we have 4^10 possibilities or 1048576 (1x10^6). Thats alot for just such a short chain.
How much would that weigh?
An average nucleotide (the base (ACGT or U) plus the binding sugar) has an atomic weight of approximately 500 Daltons. So if we multiply out the atomic weight times the number of strands divided by Avrogadros number (6.023x10^23) we can figure out the weight of those million different strings of RNA
So we get
500 x (1x10^6)/(6.023x10^23)= approx 1x10^-15 grams. THAT's 10to the MINUS 15 grams of material. That's a freakin TINY amount of stuff.
So how many solution could be in a gram(that's actually a fair amt of RNA,but anyway)
1x10^6 times 1x10^15 or 1x10^21 HUGE BRUTE numbers eh?
This isn't exactly right because you would have to make the RNA chain slightly longer (23 or 24 bases long) to get all of these solutions, but you get the point.
Of course an RNA or DNA computer won't be exactly correct. Binding mismatches can occur, you won't get truely random sequences or not all of them will form, but it will probably be MORE accurate than an electrical computer.
There are 3 issues here
1 They used another sheeps egg and implanted nuclear material into that egg. The host egg has it's own mitochondrial DNA and NOT Dollys'. There is a fair amount a variability in mitochondrial DNA which can and will lead to functional differences of the cells.
2 They used cells from Dolly that were already "aged" in her body. Cells have spacer sections (end caps is probably a better representative) on the ends of each chromosome called TELOMERES. They are long repetative segments that shorten with every subsequent division of the cell. They probably serve as some time keeper to prevent the cells from living too long and mutating to much (i.e. cancer prevention). Dolly is aging prematurely probably as a result of this.
3 - The implanted cell that they used has had it's own mutational events different from all of the rest of the cells in the body. An analogy would be to look at your skinn. Superficially it looks the same everywhere on your body, but up close you can see that it's different everywhere. Imagine your elbow skin on your face - looks different eh?
Undoubtably they would look very much like you. However environmental factors do play a role in determining how people look - they might be fatter/skinnier/shorter, etc. If you look at identicle twins you'll notice that they don't look exactly the same, yet they are essentially clones of eachother. The clonew will be close, but won't look exactly like you.
Don't hire someone that you would f***.
He could alweays pull a Ronald Reagan (during the Iran-Contra trials) and just claim that he has forgoten the key. I doubt the gov will ever crack it soon unless they do something like the distibuted net stuff. I'm not sure if they want to spend tha much money on this guy either and crucify him now that he is becoming a "cause celebrite" (where's the damn French accent keys?).
I had one once and it hurt like a sun-ova-biyatch
That's why this would be beneficial....Plus the little kiddies would like i if it were truely painless
It's hard to reply to this statement since you are pretty much in the dark about immunology.
The common cold and every other virus is able to mutate like a mofo and they do it constantly. I'm sure that the common cold and a bunch of other viruses will still be able to infect us.
Bacterial and fungal inf ections would also not be affected by this drug and would still present challenges to our immune systems.
So the bottom line is don't woory.
Pleconaril is the generic name for the medicine, e.g. the chemical name for the compound. When the drug company markets the drug, they give it a catchy REMEMBERABLE name like Virukil or something else that the PR dept thought of. That way the Docs and patients have an easier time remembering that company name for the drug and not some others company's name for it when it goes off patent. I know that most MDs usually refer to the drugs by their trade names (company names). Pfizer Pharm had trade-marked the name Viagra many years ago and were just waiting for the right drug to give the name to.
Thank God Peter Parker wasn't bit by a radioactive dung beetle.. Imagine what his super powers would be then...
If one looks at the article - it mentions THOUSANDS of new cells migrating in the monkey brains. If I recall basic pathology correctly, the human brain has on the order of TRILLIONS of cells. No mention is made of whether any functional improvement or difference was noted and the article even mention that no one knows what the new neurons were doing.
Chimps differ from we humans by approx a 1000 genes out of 100,000 or so and their brains are maybe a 1/3 of our size in the higher areas. It is reasonable to infer that if this magnitude of repair or growth occured in humans then not much of an appreciable difference would occur. Much of the (re)learning that occurs in traumatic brain injured patients(people and monkeys) involves new neural CONNECTIONS between cells - not the new growth of cells.
Other physiologic processess are also occuring in the body which may play a role in the hinderence of developing new neurons. A child can fluently learn multiple languages easily, yet an adult will with difficultly learn one or two with an accent. An infants or childs brain is still growing and has not had its developmental proceses shut down by the effects of maturation hormones.
Future research will probably concentrate on whether the adult brain cells are at the end of their lifetime or if they can be induced to be young again and divide and produce new neurons.
Not everyone likes the way Cindy Crawford or Richard Gere looks like. What if we eliminate some things such as shortness or depression - who will be the jockeys or blues musicians? Eliminate a gene for laziness and who will invent the next washing machine or remote control?
I personally have a deaf/retarded aunt and I know that much of my compassion, patience and caring have come from her influence. It will be a difficult societal choice to say yes it's okay to correct this gene for dwarfism but not for pimples. At what point do we stop and let nature take its course - nature and evolution has done a fine job of making us who we are.
a chiropractor is basically gives massages - don't expect them to correct a real problem like CTS.
As far as rubber bands go - whatever...
If you really have CTS, then you'll have a positive electromyelogram (EMG) - it's a test where a physical medicine doctor (MD) will insert electrode into your muscles and nerves in your have to look for nerve conduction changes. CTS produce a real decrease in neerve conduction velocity and a few other things. Usually a scrupulous surgeon (Orthopedic or plastic) will only operate if you have a positive EMG since the surgery will in this case decompress the nerve. If you have a NEG EMG, then the surgeon won't operate since you prob don't have CTS and the CTS release surgery will not provide relief.
nuff said.
look at the first anonymous coward reply under the first post for sigs and symptoms of the disease.
The surgery Usually provides erlief - but nothing is an absolute in medicine - too many variables - we only play the percentages.
I've tried DL'ing the 6.1version from several sources and they all seem to crash, so I would hold off a bit before DL'ing the files. I did briefly use the 6.1 Beta and it ran very smoothly (and fast), but the non-beta is still buggy - I can't install it - it just crashes even before I can select which packages I want to install
I'm a surgical resident - I can't tell you how useful this little tool is for saving patient data, operative logs, important phone, pager #'s , antibiotic data and all sorts of other crap - like when my cases are scheduled. Basically 85% of the residents in my program have one of these because of those reasons and because it keeps our lab coats from overflowing with paper junk. Plus I can sit and play a game or take care of some other stuff when I'm waiting for anesthesia to finish putting the pt. under.
You assume that someone who suffers a moral deficit and hacks a non-offensive site would act in a benevolent manner and give directions on how to fix the security flaw. Such people are more likely not to act in that manner as proven by their previous actions.
It is also possible for them to screw up and delete something important unknowlingly.
If they want to hack, go have a hacker war and hack other hacker sites.
The whole brain is used, just not all of the neurons are firing at once. When they do all fire at once it's called an epileptic seizure which is generally regarded as BAD.