Type-2 Diabetes is quite different from what is typically thought of Diabetes wherein the body is not producing enough insulin.
In type-2, even though there is insulin production, the body appears to be resistant to it.
In type-1 diabetes, without insulin - cells cannot take up glucose even though it is present in the bloodstream, making the body think it is starving and leading to breakdown of proteins etc. - leading to ketoacidosis.
This is not the case in type -2.
Just flipping thru the link, it seems the drug targets the reasons of insulin resistance namely "three key defects of type 2 diabetes can be addressed: insulin resistance, beta-cell dysfunction (decreased insulin release), and alpha-cell dysfunction (unsuppressed hepatic glucose production)."
Tagg
yes the poster is right,
its a well known fact that evolution is very infefficient and often follows blind roads and gets nowhere.
but that is for organisms whose replication rates are limited by several external factors.
for a machine or a code if the replication rate was set to a very unusually high rate and it was written in such a way that there would be an error introduced in the coding every time it replicates.. evolution would work a lot faster for them..
in fact i believe it has been (was posted on slashdot) where evolving computer programs had fooled the scientits who designed them by fiegning death to survive.
Slashdot Mirror
Type-2 Diabetes is quite different from what is typically thought of Diabetes wherein the body is not producing enough insulin. In type-2, even though there is insulin production, the body appears to be resistant to it. In type-1 diabetes, without insulin - cells cannot take up glucose even though it is present in the bloodstream, making the body think it is starving and leading to breakdown of proteins etc. - leading to ketoacidosis. This is not the case in type -2. Just flipping thru the link, it seems the drug targets the reasons of insulin resistance namely "three key defects of type 2 diabetes can be addressed: insulin resistance, beta-cell dysfunction (decreased insulin release), and alpha-cell dysfunction (unsuppressed hepatic glucose production)." Tagg
yes the poster is right, its a well known fact that evolution is very infefficient and often follows blind roads and gets nowhere. but that is for organisms whose replication rates are limited by several external factors. for a machine or a code if the replication rate was set to a very unusually high rate and it was written in such a way that there would be an error introduced in the coding every time it replicates.. evolution would work a lot faster for them.. in fact i believe it has been (was posted on slashdot) where evolving computer programs had fooled the scientits who designed them by fiegning death to survive.