Domain: ohiou.edu
Stories and comments across the archive that link to ohiou.edu.
Comments · 55
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Computational molecular biology tools"Computational Molecular Biology" aka "Bioinformatics" is the making of algorithms used to study genetic codes. I am currently taking a class on this subject, some of the professor's lecture notes are available online in Powerpoint format. Here are some of the resources I learned to use in this class:
Codon Usage Database
DNA is encoded as a series of nucleotides (G,A,T,C), but interpereted in groups of three, called "codons." This is a database of the frequencies of all 4^3 combinations for various species.Info on Blast and FastA
We can also compare the genomes of various species to see how similar they are. The above link is a short description of how two of the major programs work, BLAST (Basic Local Alignment Search Tool) and FastA (not an acroynm). There's some theoretical background on genome sequence comparison on Dr. Just's page.If you want use BLAST to search for for things with similar genomes, just grab your favorite chunk of DNA and take it on down to the BLAST homepage at the NCBI, and let it search for chunks of DNA that are similar.
Don't know any gene sequences for you favorite organism? Then head to NCBI and type its scientific name into the "Search GenBank" box at the top.If you're tired of this computer stuff, learn how actual DNA is scanned onto microarrays for analysis. Or, better yet, learn to build your own!
(And to think I was browsing Slashdot because I wanted to take a break from studying this.)
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offtopic (piglatin)
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Lashdotsay
If you thought that was sad, try this.
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Re:Not a big worry of mine.....
Surprisingly, there's not too much info out there. This is the best that I could find:
http://oak.cats.ohiou.edu/~p iccard/entropy/perrow.html
It's a review of the book Normal Accidents: Living With High-Risk Technologies by Charles Perrow. The bit about the Fermi incident is about halfway down the page.
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Re:Chris Cunningham