First Cloned Human Embryo
Human cloning, or at least the production of human embryos, is no longer hypothetical; a company called Advanced Cell Technology claims to have successfully done just that. DivideX0 writes: "The Scientific American has this article. Note the research was conducted in the U.S. although there are bills pending in Washington that will ban this research." There's also a story at MSNBC. Update: 11/25 16:07 GMT by T : Here's ACT's press release as well.
And i wonderr what defects theis cloned embryo has... It's a known fact that cloned DNA is weaker and ages faster than the actual original DNA.
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Why should research be banned that could allow you to "grow" a new heart (or liver or whatever) if yours breaks somewhere down the line? If this research ONLY allowed people to get heart transplants without waiting on infinitely long waiting lists for someone to die, imagine the benefit to medicine.
If the U.S. bans this research, it will simply move to other countries. Imagine having to live in China or Russia for a while to get your heart transplant because saving your life this way in the U.S. is illegal.
In my opinion, the U.S. should ban cloning an entire human for whatever purpose, as this could be used for some very evil things. But banning research is stupid.
If you can get your representative to draw a distinction between therapeutic cloning (make young healthy cells to repair damage in the host) and reproductive (make a baby), hats off to ya. Want to go for the jackpot? Explain it to the satisfaction of the religious right. I agree with your position, but adopting it would lose a congressman votes among the enormous "no attention for an argument longer than a bumper sticker" constituency.
As for the posts which talk about the weaker DNA and shortened life of clones, RTFA! There's a difference between cloned embyonic cells and cloned adult cells. But try explaining that to Slashdot. Much cleverer to say "Three thumbs up for cloning!" or the like and move on to other matters.
Actually, the birth rate in the U.S. and in much of the 'first world' is below replacement level (and in some places, is precipitously low -- Italy for one).
Population increases will continue for a couple of decades due to inertia, imigration, and lengthening lifespan, but if the trends continue, the population will decline.
Of course, this isn't all rosy news, as it means a world with many old people and few children -- in some countries the median age may well approach 60!
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2. genetic imprinting. Fertilized zygotes have DNA contributions from two parents, whilst cloned embryos only from one parent. DNA is often covalently modified (e.g., methylation) in a process called imprinting, where the modified allele is silenced. Modifying these silenced alleles often has deleterious consequences.
3. Telomere length. Chromosomal ends are maintained by special DNA structures called telomeres. The lengths of telomeres are often different between different cell types, and usually reflects the state of differentiation of the cells. Telomeres are known to affect life span and this is probably one of the main reasons why cloned animals have poor life spans.
There are just some factors that I can think of off-hand, I'm sure there are many others. Just because organisms have identical DNA sequences do not mean that they will develop identically, even if you do not take environmental effects into consideration.
Don't get me wrong, I am all for cloning and stem cell research, but it is prudent to think through ethical concerns before plunging ahead.
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If we ban cloning does that mean monocellular life will be against the law? Cloning is something readily done in nature, your entire body is constructed of cloned cells. They've all got your DNA and act just like the other versions of themselves.
What cloning won't do:
1. Allow you to make a clone of someone and replace them in society with an exact replica. A clone of me made tomorrow would still take a normal amount of time to grow up and may or may not be anything like me. Genetically we'd be identical but unless he traveled back in time to live my life for me he probably wouldn't end up anything like me.
2. Allow me to create an army of super clone warriors to take over the world. Said soldiers would have to be gestated and raised like a normal army of soldiers.
What cloning embryos WOULD allow:
1. Do gene mapping and stem cell research with a very large subject base with little genetic discrepency. Every wonder why fruit flies and a few simple plants have been used for the past whatever years for biological experimentation? There's little genetic diversity and they're plentiful.
2. Figure out how to regenerate cells by cloning them so you can repair almost any part of the body damaged by just about anything. There's not a whole lot of a chance for rejection when you're your own oragan donor.
Cloning research doesn't require an embryo to be gestated. Then of course there are those holding to the notion that life begins as an embryo and all that jazz. That is just picking at straws because you don't have enough understanding of the process to make a logical argument against it. If you want to save a baby stop jacking off and ovulating but don't harrass somebody trying to make you and your kids have a better life.
I'm a loner Dottie, a Rebel.