Slashdot Mirror
Human-Mouse Hybrids?
scientistguy writes "There is a remarkable story by Nicholas Wade in the early
morning edition of the New York Times about a discussion to create human-mouse
hybrid organisms. One of these techniques involves the introduction of genetically altered mouse embryonic stem (ES) cells (e.g. with
genes 'knocked-out' or replaced) into a developing mouse blactocyst to create progeny hybrid organisms. Typically, these progeny organisms are then bred to unaltered mice to see
if the genetic alteration has gone germline or is heritable. If heritable, mice can be bred and
animals which are homozygous for the altered gene can be phenotypically examined as long as the manipulation is not homozygous lethal or cause
sterility in a single copy state. Unless using
blastocysts from immunologically crippled mice, there would most likely be a recognition of non-self by murine immune cells not educated (which haven't seen during their development) to the human cells that would wipe them out. Nonetheless, it's amazing that it's
being contemplated due to the ethical implications of such an experiment. What if it were viable? What if there were more than just a few
human cells? Could it be sacrificed? ... or even experimented on further if part 'human'? Perhaps these
types of experiments are best relegated to little known, deserted islands far
away from the reaches of civilization (or perhaps regulation) ..."
What - like Australia ?
blactocyst to create progeny hybrid organisms
Good god! Don't you understand the implications though? If the digital tri-mode defrobulator gets out of sync with the anticalisthenticator, we could have some serious subdermal anamolous activity!
Open your eyes man!
(I just thought the sentence sounded funny the way it was strung together, even if I do have enough biology to know what a blastocyst is and to recognize when it's misspelled)
-- Truth goes out the door when rumor comes innuendo. -- Groucho Marx
Oh very freaking funny you insensitive clod!
An Eye for an Eye will make the whole world blind - Gandhi
If this research continues, it might only take
1000 genetically altered monkees 10 years to create
the collective works of shakespeare. You probably
wouldn't have to lock them in a room either. They'd
of course be superior and have 3 asses.
The most important thing any republican needs to know.
This Human-Mouse hybrid sounds like a great advance in the computer interface design. At least it would remove one bottleneck. Soon we'll outquake even Dustpuppy (he uses a separate mouse).
Escher was the first MC and Giger invented the HR department.
I don't understand. Is there an English copy?
I shoved that into babelfish but it didn't come up with anything - no matter what language I selected...
I consider myself open to scientific experimentation
That's pretty brave. I'm just an organ donor myself.
The most important thing any republican needs to know.
They're creating an army of Mouse-men to take over the world. An army of millions that will scurry out of rural corn fields and take over America.
Fortunately I am almost finished designing a giant trap that will prey on the one weakness they neglected to genetically correct, Sweet, sweet, cheese.