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Ontario Ignores Gene Patent

Anonymous Coward writes "Well, for once my government the Ontario Tories have done something right. You see, there's this cancer test that involves a gene sequence patented in Utah. Thankfully, my goverment decided to ignore the patent and help out those who need it. Ah the joys of living in such a liberated country." Different provinces have made different decisions about this particular patent.

33 of 68 comments (clear)

  1. Q. Patents are valid across countries? A. ??? by UnknownSoldier · · Score: 2

    See subject.

    1. Re:Q. Patents are valid across countries? A. ??? by swagr · · Score: 2

      > Yes, lets discourage further development in the cure for cancer.

      No. It inhibits the ability of profiting financially (or not losing money) from a cure for cancer.

      For some, that may discourage their development. For others (say a researcher who's mother died of cancer) it may not make a difference.

      --

      -... --- .-. . -.. ..--..
  2. Don't be too happy by Anonymous Coward · · Score: 4, Funny

    Ah the joys of living in such a liberated country

    You'll be less pleased when GWB names Canada as a new member of the Axis of Evil in his upcoming State of the Union address because of your "intellectual terrorism".

  3. Sure... by breon.halling · · Score: 3, Funny

    ...they can ignore patents, but not my collection of unpaid parking tickets. ;)

    --
    "Yeah, well, Dracula called and he's coming over tonight for you and I said okay."
  4. Why thankfully? by MacAndrew · · Score: 2, Interesting

    I sympathize with the questions raised about genetic patents, and worry more generally much more about the threat of profiteering by companies that develop life-or-death health technologies, and the plight of people who can't afford essential care.

    But here, the poster is complimenting getting a free ride on the work of others. This is not "liberated" thinking, it is merely a bid to save money. It does not take a lot of imagination to project that too many free rides will lead to few if any rides.

    Surely there is a middle ground, compensating the developers as one would for a new drug, while avoiding the trickier implications of patents on genes. When it comes to money, this action is no different than immediately making a generic version of a newly developed drug.

    1. Re:Why thankfully? by Anonymous Coward · · Score: 2, Informative

      Myraid Genetics is charging outrageous amounts for the test and saying that nobody else is permitted to test for the presence of the genes. The Ontario doctors have come up with their own test, but Myraid is crying foul because they claim to *own* the gene.

    2. Re:Why thankfully? by salesgeek · · Score: 4, Insightful
      But here, the poster is complimenting getting a free ride on the work of others.


      Genetic patents are patently ridiculous because they almost always involve discovering prior art and patenting it or the process used to observe it. Generally, genetic patents are not novel or new in any way. They are akin to patenting basic algorithms being applied to basic operations - for instance, building a b-tree to store and retrieve strings in one patent and integers in another.

      Congrats to Ontario for seeing genetic patents for the farce they are. I could care less about the profits of a few would-be monopolists over the lives of even one or two people. Save the people, have compassion on the sick, and most importantly, don't value money over the lives of the poor. You could be poor one day.

      $G
      --
      -- $G
    3. Re:Why thankfully? by MacAndrew · · Score: 2

      You are hopelessly shortsighted and must live at home.

      If you had a million to invest, would you choose a genetic research project where you would lose it all? Hmm. Wonder if that research will ever get private funding?

      You have no compassion for the sick if you would bankrupt research into cures.

    4. Re:Why thankfully? by MacAndrew · · Score: 2

      Yep, that's part of the problem with genetic patents, which strike me as very strange. I think patents are a mistake, but want to encourage genetic research by all means, private and public.

      Did the Canandian researchers benefit from Myriad's research? If they did, they should compensate them. I hope the sides will settle this in some way, and if Myriad's work was beneficial that they are compensated for it, including a reasonable profit.

      What I don't believe is "because genetic patents are wrong, Myriad's work is a freebie."

      It's the Canadian gov't footing the bill here, isn't it? Canadian funding for health care is far more generous than in the U.S.

    5. Re:Why thankfully? by salesgeek · · Score: 2
      You are hopelessly shortsighted and must live at home.
      Cute. So I'll answer in kind: Like most people, I live at my home. My wife, kids and cat live here, too.
      If you had a million to invest, would you choose a genetic research project where you would lose it all?
      I would not invest in anything where there is a 100% chance of loosing it all. So what's your point? How do genetic patents produce cures anyway? Genetic patents gridlock real applied science by locking up the genome and the methods used to manipulate genetic material for the next 25 years...
      You have no compassion for the sick if you would bankrupt research into cures.
      What's a human life worth, in Euros, please? I believe the discovery of a cure should be rewarded, but not at the expense of human lives. Nor do I think discovering something that occurs in nature is novel or an original invention.

      $G

      --
      -- $G
    6. Re:Why thankfully? by d_i_r_t_y · · Score: 3, Insightful

      i know what you're trying to say but it's not right. the patenting of genes occurs solely to prevent others (other comapanies, research institutions) from exploiting/developing cures through the exploitation/manipulation of that gene.

      the fact is, discovering a potential gene/therapeutic target is only the first step in a long (10-15 years) and arduous road to a publically available cure/therapy, which is when the financial floodgates finally open (wide). the gene itself is worth nothing (in terms of $$$ value of course) until a therapy which exploits that gene or its gene product is discovered, and THAT'S where the money is. that and only that is what should (usually) be protectable/patentable.

      GENETIC PATENTS ARE FUNDAMENTALLY WRONG because they prevent others from developing or even researching potential therapies right at the beginning of the discovery pipeline, which clearly and absolutely PREVENTS innovation/discovery and is AGAINST the public good. the innovation is the *therapy* that exploits the gene, not the gene itself. i can "discover" a (likely) new gene with some cheap and nasty perl and the publically available celera sequences, but what does the gene do? is it "important"? how does it work? does it cause, or correlate with, the incidence of some disease? how? etc etc. surely i shouldn't have the right to claim (patent) that gene as my "invention" until i've shown that it does something interesting and can demonstrate a method of its exploitation, right?

      all in all, GENE PATENTS ARE MERELY SPECULATIVE LAND-GRABS, like someone bursting into a department store on the first morning of the post-christmas sales and then staking a claim on all the bargain bins whilst crying 'i got there first!'. the bargain bin should be open to everyone until someone picks something of value out of it, right?

      in the same way that all web-savvy people decried the ridiculousness of amazon and others with their ludicrous patents, anyone worth their salt in molecular biology/biochemistry knows that GENE PATENTS ARE JUST WRONG WRONG WRONG.

      - a card-carrying scientist

  5. Re:Proud... by retards · · Score: 2, Insightful

    Perhaps developing life-saving "technology", like genes, should not be done by coprations striving only for profit for their shareholders? People who are sick or perhaps dying will not listen stupid analogies about cars being stolen. According to some, I seem to remember, the business of a state was to see after the well being of it's citizens, not the well-being patent-driven pharamceutical companies located in other countries.

    If you can give me any example or argument where money is more important than life, I will eat my hat.

  6. Patenting Genes by 56 · · Score: 2, Interesting

    Wouldn't that mean that just by having that gene sequence you are violating their patent? I can see how they can patent the method to test for this gene pattern, but not the gene pattern itself.

  7. prior art by J+x · · Score: 2, Funny

    Since we all have prior art on the human genome, shouldn't it be "open source"?

  8. What is the patent for? by nuggz · · Score: 4, Insightful

    This is an important distinction.
    If they patented the gene, it is already existing naturally, there is no reasonable infringement.

    If they patented the procedure to detect the gene, they shoul get the benefit of their research (assuming it is a valid patent).

    If they patented the gene as a method to predict cancer, then the arguement is quite murky. Finding cancer by looking for it is obvious. Finding cancer by looking for other unrelated factors is probaly a valid patent.

    If this gene sequence is related to cancer (causative or a result of) then it is related to the having of cancer (like cough due to cold).

    Maybe they just have a good patent lawyer.

    1. Re:What is the patent for? by Daniel+Dvorkin · · Score: 2

      I believe that Myriad is claiming that any test for the gene infringes on their patents -- which isn't quite the same thing as claiming to have patented the gene itself, but it's damn close. I see this as part of a general problem with patents being granted for ideas instead of implementations, which is inherently fucked up.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    2. Re:What is the patent for? by MillionthMonkey · · Score: 2

      Genes should not be patentable. Patents are for inventions, not discoveries. A specific test involving a gene can be patented, but I've never heard any coherent rationalization as to why a gene itself should be patentable.

      I say this as someone who makes his living by writing gene expression analysis software for pharmaceutical companies. Gene patents help me put food on my table but I can't deny that they're ridiculous.

  9. If only by mnmn · · Score: 3, Funny


    Proud to be in a country that does this. Now if only Canada:

    (1) Ignores all copyrights on MS Windows
    (2) Leaves the ranks of GWB's warmonger party.. ..would be a VERY nice (albeit cold) country to live in.

    --
    "Give orange me give eat orange me eat orange give me eat orange give me you." -Nim Chimpsky
  10. Re:Proud... by Catskul · · Score: 2

    That is not the argument. (mind you with this post I take neither side of the argument, Im just explaining it)

    The arguement is that if the gene patents are not respected then companies who make money off of those patents will stop developing the "life-saving technology". And we all know that if it didnt make any money they really would stop development. The question is now how many countries (or states or what-have-you) have to ignore the patents before it is no longer profitable to develope them; and who gets to ignore the patents if it is still profitable with just a few soverign untities ingoreing them. So Retards(not a flame, the guys sn is retards) no one is saying that money is more important than life, in fact its being said that if you ignore the patent fewer lives will be saved in the long run because of someones hasty shortsighted good intentions.

    Now the real other side to the arguenet is (note: I have already debunked the money vs life argument): What are the implications of being able to patent a gene. Can I patent a gene that already exists in nature, can I patent a life form? Can I sue you if somehow my patented gene gets into your crops/products/whatever? What if I have patented a gene ahead of other reasearchers and refuse to lisence it to poorer nations at a reasonable price? What if my patented gene gets into another crop/product/whatever and causes damage? Am I responsible legally for that damage? What if someone not from my company did the contaminating?

    Could the academic communtiy produce these "Life saving technologies" in the time and quantity that the corperations do. Probably not. But would more lives be saved with fewer, but freer technologies ?

    All of these things are very important questions, some of which have disturbing answers. Both sides of the arguement have very valid points. Dont be a party politics person. Be a moderate and consider all sides of every arguement. Chances are if people are argueing about it, there are important points on both sides of the arguement that are woth worrying about.

    The answer is almost always a compromise. Restrictions on lisence fees, restrictions on length of patent protection, exceptions to the protection, etc. Corperations do often have bad intentions, but unintentionally produce alot of good in the world. That is the whole concept of capitalism, to use natural tendencies to do good and to create a system with checks and balances that converges (hopefully) on the perfect system (if very slowly maybe).

    --

    Im not here now... Im out KILLING pepperoni
  11. How you patent genes by Anonymous Coward · · Score: 2, Insightful

    Gene sequences can be patented in the US and many other countries because the naturally occurring sequences have "junk DNA" intervening between chunks of "coding DNA" that contain the actual genetic information. So a natural gene might look like this:

    AxxxBxxxxCxxxxxxxxxD

    where the x's represent the junk.

    The patented gene sequence would look like this:

    ACBD

    So, you would not violate a company's patent by having the naturally occurring gene in your body.

    The idea is to reward the effort it takes to identify what a gene does and isolate the sequence needed to reproduce the protein the gene codes for.

    Now, when it was hard to do that, a patent might be warranted. Whether that is still the case now that it is quite easy to identify coding regions and sort-of "reverse engineer" what the gene does by sticking the code into a mouse, or removing the mouse's version, etc etc etc., and now that all the methods are very well known to someone "versed in the art," is a matter of much debate.

    1. Re:How you patent genes by VikingBerserker · · Score: 3, Funny

      So a natural gene might look like this:

      AxxxBxxxxCxxxxxxxxxD

      The patented gene sequence would look like this:

      ACBD

      They've patented the gene sequence for dyslexia?

  12. GREAT!!! by Anonymous Coward · · Score: 3, Insightful

    Awesome.. i whole heartdly support them..

    here's the real kicker..

    "The tests cost about $1,100 each but Myriad, which also holds gene patents for screening of colon and prostate cancers, wants all tests done at its own laboratory at triple the cost."

    Cost of healthcare is high enough.. and don't tell me they aren't making a dime when a test costs $1,100 each to begin with, not only that but cancer testing will remain IN CANADA, not in a foreign (not like the US is far away) country.

    Sickens me to see my tax dollars wasted, but this is one good sign. With several relatives either gone because of cancer, or currently have cancer, prescreening is important and makes curing and treating cancer that much more possible.

    - Happy Canadian flippin the bird at stupid US patents.

    1. Re:GREAT!!! by Mad+Marlin · · Score: 2
      ... With several relatives either gone because of cancer, or currently have cancer ... Happy Canadian flippin the bird at stupid US patents.

      The only way that medical problems such as cancer will be cured is by medical research. If medical research companies are not able to recover their investment, then the research will stop. They are in the business to make money, and are trying to make money in a very honorable way, helping to fight major medical issues.

    2. Re:GREAT!!! by Mad+Marlin · · Score: 2
      Unless, of course, they go back to public funding for such projects.... Here in Canuckistan, we're weird that way.

      Why didn't I think of that? A massive government agency to spurn innovation in medical research, by having civil servants deciding who is the most deserving of the funding, instead of the free market. Now that seems like a really good idea.

  13. robin hood? by Unordained · · Score: 2, Insightful

    i think that argument has failed before: "it's okay because it's for a good cause" ... i'd prefer someone just stand up and say "no, it's a stupid idea in the first place, just ignore all such things."

    as stated by many, patenting a method for detecting a gene is one thing -- keeping other researchers from using home-grown methods to find that same gene is another. and claiming the gene for themselves is just right out.

    patents were designed to give those who invested in research a return on those same investments, by giving them a temporary edge on the market. i believe it's important to reward such research, especially in the medical field. it's sad to see anyone, rich or poor, suffering from disease.

    in the end, though, we must remember that both patents and copyrights were designed to override the default rule: we all own information of this sort. they are not permissions for us to have this knowledge after a time -- they are permission to keep it private for personal gain for a limited time. they are incentives, not inalienable rights.

    do you support what could become (or is) extortion? inexcusably high fees for access to patented methods? life on the life, too bad, pay up? do you support, from the medical field, the practice of not revealing life-saving information for personal gain?

    questions like this are -not- to be answered with the robin hood argument. whether 'tis for the rich or the poor, the same question must be answered -- what is the value of life?

  14. Re:This is good news? by Blkdeath · · Score: 2
    But Canada grabbing a gene patent? Canada is among the richest countries in the world and this patent does nothing to help poverty-stricken, plague-addled victims. This looks like yet another socialist power grab by our neighbors to the north.

    They patented a gene sequence. A sequence that probably exists, and has existed in millions of women for thousands of years. It's like patenting a phallic shaped appendage that dangles from approximately 1 of every 2 individuals, or blue tinted irises in the eyes of North American males. It's a ridiculous, prohibitive patent and I applaud my government for telling this corporation to stick it.

    If, and only if, the patent covers the specific methods by which to identify the presence of these sequences I will agree that there should be some renumeration to the corporation, but it's unreasonable to expect to have patients shipped down to Utah (on whose nickel, I might add?) to perform the tests at triple the cost they could be performed here at home. Why can't the company atleast permit the tests to be performed locally with royalties transferred to the company?

    Myriad is being completely unreasonable, and I really hope the Ontario government wins and sets a precedent against gene sequence patents. Nobody has the right to patent something that's existed in my body since my conception; period.

    --
    BD Phone Home!

    Shameless plug. Like you weren't expecting it.

  15. Method Patent by nuggz · · Score: 2

    You can patent a method.

    Lets suppose much baldness is cause by a gene, please neglect the obviousness of my idea.

    Method to predict future baldness.
    Look for gene XXX in subject, if found, they will become bald.
    Analyse biological relatives for baldness, if many are bald, the subject will likely become bald.
    Baldness genes are in masturbatory semen, if the father watches too much pornography, the subject will have a higher likeliehood of baldness.

    These "methods for detecting baldness", depend on the discovered science. But that does not mean they are not methods for doing something.

    Discovery is a vauge term, and patent law doesn't state you can't patent discoveries, it defines what you may patent.

    1. Re:Method Patent by MillionthMonkey · · Score: 2

      Yes, but this is in agreement with the parent post that I wrote- it's an argument for patenting a method (a specific test involving a gene), not for patenting the baldness gene itself.

      We were really nervous with the loose wording in the CBDTPA when that was being talked about in Washington last year. We'd have to suppress certain genes from appearing in gene expression profile graphs if someone other than the user held a patent on them.

  16. How good is this? by BCGlorfindel · · Score: 3, Insightful

    First off, I am against large pharmaceutical companies profitting off of the sick and dying. But before heralding this as a victory for freedoms, the flipside also deserves some consideration. Like it or not, research into cures for diseases require money, period. This research is very expensive, and thus so are the resulting products. I can understand trying to cut excessive profiteering on new found medicines(or tests in this case) but if any nation can afford to pay some cash for the research that was done, surely we Canadians are one of those nations... Unless of course the price asked was in American dollars :)

  17. Re:Proud... by Catskul · · Score: 3, Insightful

    The argument for enforcement of patents is not dissimilar from software or media piracy.

    I disagree. Comanies always want more money. I think the scenario here is that its not really ok to copy music/video/etc (though we all do), but its also not ok, and much worse, to impose a fascist policy to stop it. If you can police it through normal means go ahead, but if you have to create all kinds of new laws that take away the rights of the citizens, then you have to find another way, or find a new business model.

    In my opinion a society is in very big trouble the second it's citizens realize that the answer to the question "Am I going to die?" is "Do you have money?".

    Whether or not you are right, Its always been that way to some degree and will continue to be. You could follow a communist philosophy (and I dont mean this as a flame) and try to make sure everyone gets equal treatment, but very likely (as we have seen) the total number of people (as well as total quality of help) goes down dramatically and still there will be those with more that will get better help.

    As far as the sweatshop question is concerned, I seem to have a very different view of the situation. I see the problem is not the wages these people are paid, but the danger that they face with the machinery. All in all it is my belief that over all they are better off with the work that corperations bring to their countries. These people would otherwise need to work somewhere else and no doubt for less money. With companies seting up factories into these countries more money is being dumped into their economies. I think they must go through their industrial revolution as we went through ours as painful as it might be (it was for us also). Yes there are bad things that happen, but in the long run (I think)the country will be better off.

    No I dont believe the companies are taking work to those countries for the good of the people, but I do believe that is the effect.

    I dare say that we are very far from that original ideal.

    Maybe you are right, but Its hard to see the big picture. I hold some faith in capitalism not because I think those who participate in it have lofty motives, but because the system expects them not to.

    --

    Im not here now... Im out KILLING pepperoni
  18. Reciprocity is the word by marcus · · Score: 2, Insightful

    I imagine that there are a number of compainies in Ontario that are wondering if all of their development efforts have been wasted.

    Usually, patent treaties and their like are reciprocal. I'll honor yours if you honor mine. I wonder what will happen to the Ontario economy when the US starts to ignore patents filed by residents of Ontario? Regardless of the technical validity, or lack thereof, of gene patenting, frankly it seems that Ontario has much more to lose.

    --
    Good judgement comes from experience, and experience comes from bad judgement.
    - W. Wriston, former Citibank CEO
  19. Re:Proud... by Stoutlimb · · Score: 2

    Actually the poster did not miss the point. Everyone is taking this to the extreme, comparing it to theft from the company on one end, and from the other side, saying that genetic patents should be abolished.

    The government of Ontario takes neither of these extremes. Their opinion is that if a company ABUSES their patent, and it harms the public good sufficiently, then the government has the right to ignore that patent.

    There's enough posts in Slashdot about companies abusing patents, and here's a posting about a government doing something about it.

    The message the Ontario government is sending to companies is not your extrememe "Companies can't profit off of their discoveries." Not at all. They're saying "Companies better be fair with how they profit from their patents, or those rights will be taken away."

    Not such a bad idea, if you ask me.

  20. Trust big business? by geoswan · · Score: 2
    The only way that medical problems such as cancer will be cured is by medical research. If medical research companies are not able to recover their investment, then the research will stop. They are in the business to make money, and are trying to make money in a very honorable way, helping to fight major medical issues.

    Don't pharmaceutical companies have a terrible reputation for dishonesty? Here is a link to a story about Apotex . Short version? Pharmaceutical firms routinely get researchers to sign documents allowing the firm to gag them, if they discover information about the drug that would be bad for business. The lead researcher, in this case, Dr Nancy Olivieri, discovered there was a very harmful side-effect of the drug in question, and wrote letters to the parents of her young experimental subjects. And Apotex went ballistic, and tried to ruin her career.

    This is not an isolated case. This kind of thing happens all the time. Usually you don't hear about it because the researchers fold.