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Biotech Genome Patents Invalidated?

bruthasj writes "The Boston Globe has a piece about all the Biotechs grabbing patents that dealt with segments of the Human Genome. It appears there are work arounds and that the USPTO basically disregards further patents on the genome. As one quoted: ''The land grab is over''. Read about it here."

21 of 148 comments (clear)

  1. what about by jsse · · Score: 5, Insightful

    previous patents? I think USPTO should admit their mistake and invalidate them too.

  2. Talk about double jeapordy... by kryonD · · Score: 4, Insightful

    Just imagine being told you have cancer....and then being handed a law suite for not licensing the process of mutating human DNA.

    If only the USPTO would wake up to other scemes like this.

    --
    I've dirtied my hands writing poetry, for the sake of seduction; that is, for the sake of a useful cause. --Dostoevsky
    1. Re:Talk about double jeapordy... by aussersterne · · Score: 4, Insightful

      You paint this to be a kind of extreme worse-case scenario...

      And yet, you shouldn't doubt for a moment that if large corproations could charge you or garnishee your wages simply for getting cancer, they would. I mean, think of how many people get cancer! And by extension, think of the profits! Definitely worth the "investment" in a couple of patents here or there.

      This is the world of Ayn Rand. These are the evils of capitalism. The combination of a patent system run amok and technologies which involve human DNA have given us a glimpse into just how evil capitalism can become... it just goes to show that whether you believe in capitalism or not, you must at least be willing ot put checks on it, lest it rise up and own you and your children (literally).

      --
      STOP . AMERICA . NOW
  3. I just don't understand by Anonymous Coward · · Score: 4, Insightful

    This seems asinine to me. How can somebody claim a patent on genes?? Isn't that like patenting gravity or sunlight?? I thought you had to invent something to patent it. Marconi patented the radio, he didn't patent radio waves. (and yes i realize he may not have patented the radio, but it did sound good. :)

    1. Re:I just don't understand by Lars+Arvestad · · Score: 4, Insightful
      I don't think anyone simple claimed a patenet on a gene, because you had and have to claim a utility of it. What happened was that people/companies found a gene or even a small part of a gene, sent it to a patent office and claimed "Uh, this is a gene, and, like, we could cure cancer or something with it, so we want to patent that any other use of it." The support for the utility did not have to be very good and the patent would still go through. The applicant may in reality not have a clue about the gene more than that it was most likely a gene and it looked like something else that people knew might be used for something, at least in worm or fly or some other model organism...

      So it was more like people said "I want to patent the use of gravity to cure cancer. I have no idea how to go about with it, but darn it I am the one to prosper from it would a use someday appear!"

      --
      Reality or nothing.
  4. do they even check? by 7-Vodka · · Score: 4, Insightful
    does the patent office even check if the submissals actually exist/work whatever as claimed?

    or do they just pay 10,000 monkeys to read through it then rubber stamp it?

    I read the whole article and I don't see anything that mentions how these patents are actually checked/verified.

    just says they're getting 'stricter'. Well boo-hoo. Before they just rubberstamped any shite that came thru, and now you have to tell them a little bit about the shite before they rubberstamp it without checking.

    --

    Liberty.

  5. What a surprise by Strange+Ranger · · Score: 3, Insightful

    All along the way to make money from genomics was not to file patents.
    The way to make money is to cure disease, repair injuries, and extend life. I'm glad it only took a few years to clear THAT up.

    Now let's hope Bush doesn't have too many of our best and brightest running from his lynch-the-cloners plan.

    --

    Operator, give me the number for 911!
  6. Knuth said it best ... by zonix · · Score: 2, Insightful

    When we start thinking of complexity issues, we have to change our viewpoint as to what is in nature and what is invented.

    z
    --
    What would an EWOULDBLOCK block, if an EWOULDBLOCK could block would? -- me
  7. new gold rush? by psyclone · · Score: 2, Insightful

    seems like we're in a crazy new age of intellectual property being the new gold. I wonder what other areas of research should be limited on new issued patents. Will there soon be a trend of lowering the patent issue rate for all types of patents? Or is this only local to genetics..

  8. something people are overlooking... by zonker · · Score: 5, Insightful

    while i wholeheartedly agree that patenting things like genes seems obviously public domain and incredibly prior art, there is a bigger issue at hand... money.

    several people in my family are scientists involved in genetic engineering and we have had this discussion many times. the point that they make is that pharmaceutical companies must be able to secure their findings to pay for the research they do to find these genes and produce drugs to treat various diseases. remember that companies like merck aren't doing research like this because they are simply curious, no instead they want to find things like the cure for cancer or diabetes or aids or the common cold because it makes them money.

    this research is ungodly expensive, so the drug companies want to make sure that if they did the research and found something, their competitors won't be able to cash in on it before they do. or worse yet, some company in asia making pills for next to nothing. this is their greatest fear, and this is why they patent things like there is no tomorrow.

    while i still find it morally and ethically wrong to patent things like genes, i can't come up with a better way for these companies to do their business. and as much as i'm not into big businesses, i do like staying healthy...

    1. Re:something people are overlooking... by The_DOD_player · · Score: 2, Insightful

      Ofcourse the medical industry need money to finance their research.
      But you cant justify anything only on the fact that you need money. We have people robbing banks because they need money -- does that make them right?

      So no, money is NOT the bigger issue here.

    2. Re:something people are overlooking... by 91degrees · · Score: 5, Insightful

      They can still patent developments from genes. They simply can't patent the genes themselves. There is a big difference between isolating the genes responsible for a certain type of heart complaint, and using those genes to develop a treatment. They still get repayed for their investment. It's just that the bar has been raised. They need something with a direct application rather than something that may or may not be required for a certain application.

      This does mean that they may be obliged to discover the genes themselves before developing the treatment, but they have the ability to do this. They can simply rely on trade secrets laws to prevent others from using the gene sequence, and equally, they can licence trade secrets. Their payoff is from the patent on the treatment, not the genes.

      The benefit is that this does still encourage information sharing, but also prevents extortionate charging for the root IP. You can choose to licence the information, or if the other company charges too much, you can simply rediscover it yourself. The risk that another company would start charging unfair amounts was a disincentive to actually develop anything based on publically available genes.

    3. Re:something people are overlooking... by the+gnat · · Score: 2, Insightful

      Damn straight. The other distinction is that genes are found as part of basic research, whereas drugs (which I absolutely think should be protected) are an actual useful product. Gene patents are simply being used as a stranglehold on basic research by competitors; companies file huge numbers of patents because they're hoping that somewhere down the line, somebody else's research pays off and then that other group will be forced to share the wealth.

      Science is all about risks. The purpose of the patent system is not to reward risk or investment, but to promote the development of useful stuff.

  9. Re:Leaps and Grounds by l810c · · Score: 4, Insightful
    DNA, Periodic Table, Physical Laws...etc...

    I don't it should be possible to patent 'information' that is by its own existence 'prior art'. Processes to extract, create, manipulate this information should be patentable.

  10. Copyright by Dusabre · · Score: 4, Insightful

    Like I mentioned in the other post, COPYRIGHT is something different to a patent.

    Copyrights on human gene sequences cannot be given. Why? Because an 'author' gains copyright. Nobody can author something that other people carry with them from birth as a chemical sequence. Even if a sequence was copyrightable then you would not have to license your DNA from Big Bad Corp because you are carrying it a chemical form, not a sequence of letters, etc etc.

    A patent on a practical usage of a sequence is a completely different matter. Inventions using already occuring elements are fine under law and fine for most people. If somebody patents ATATATAT as a sequence used in a drug to boost human intelligence, then they're creating a new drug using that sequence, in the same way that a hydrogen engine uses naturally occuring metals and hydrogen to push a car. Usage is key and it seems that the Patent Office is pushing the usage aspect. Thankfully.

  11. Gene sequences are not inventions by emh0 · · Score: 3, Insightful
    I really don't see how gene sequences are patentable anyway - I always understood that patents were to protect inventions. Gene sequences are discoveries, not inventions - there is a big difference.

    There is also the ridiculous situation where everyone is surely in breach of the patent, since everyone contains a copy of the patented DNA.

  12. Re:Leaps and Grounds by k98sven · · Score: 3, Insightful

    I don't it should be possible to patent 'information' that is by its own existence 'prior art'. Processes to extract, create, manipulate this information should be patentable.

    It isn't.
    What biotech patents are all about is "using information x to do y",
    for example: "using a breast-cancer gene to detect patient suspectibility to breast-cancer".. etc

    The problem with biotech patents is that these claims are vague, and the application in question is often obvious.
    That's where the problem is

  13. Breast cancer gene by octalgirl · · Score: 3, Insightful

    I hope this invalidates that patent on the breast cancer gene, discussed here.

    It is just stunning to me that could be issued in the first place. And the company was actually using their patent to try and stop others from treating the gene, because it was their gene? Human body parts of any kind should not be patented. This may sound sexist, but I think if that was a testicle gene the patent never would have been issued. (sort of like the viagra vs birth control debacle)

  14. Loophole by dissy · · Score: 3, Insightful

    One loophole is really simple.

    Patents are for inventions. No court can really argue this.

    So say I discover a gene, and later find a way to cure something by using that gene.

    I can simply go ahead and do so, as long as no other companys cure the same problem with the same gene.
    If all they have done is patent the gene, I am free to ignore that.

    So say they did patent the gene I use, and attempt to sue me.
    I can be nice and explain to them the error of their way, but legally im not required to even respond directly to them.

    So they try to sue me.

    All I would need to do in a court of law is have them show their invention using the gene to the court. This is how two partys would prove that my invention is not the same (or if it is.)

    They will have no such invention.
    (Like i said, if they do, they have a valid process to patent, and life goes on.)

    So at this point its safe to conclude that my invention (curing something by using this gene) does not at all match anything they are doing.

    No patent infringement issue at all.

    A judge could not claim a gene itself is patentable. At that point any living person is prior art which will invalidate the patent fully.

  15. Any other biochemists out there cringe at this? by Milo+Fungus · · Score: 2, Insightful

    From the Article:

    "In the 57-page patent, 31 pages are filled with streams of As, Ts, Gs, and Cs, letters that represent the four amino acids that make up the DNA fragments that relate to the kinases." [emphasis added]

    OUCH! Amino acids do not make up the genetic code! ATGC are nucleotides . Amino acids are the building blocks of protein. The amino acid sequence of proteins is encoded in the sequence of nucleotides in nucleic acid.

    I realize that this post could be considered a nitpick, but to me it's not. It's like a software designer reading somewhere that the source code for an application was "written in the XML programming language." Doesn't that make your gut clamp up? Or what about, "Internet Explorer is my operating system?"

  16. Re:Leaps and Grounds by the+gnat · · Score: 2, Insightful

    Fair enough. But there's two ways to go about it:

    1. You discover a gene, and patent it. In the worst case, everyone is prohibited from doing research involving this gene without your approval for 17 years. Even if you're incapable of doing anything with it, like most of the companies with huge numbers of gene patents.

    2. You discover a gene, and copyright your database. Others who wish to use your data pay you for access to the database. Anyone who doesn't want to pay can find the damn gene themselves, which takes time and money but isn't illegal.

    Celera primarily chose (2), and received far more abuse than it deserved for their choice. They certainly shouldn't have been forced to make any of their data public*, but they shouldn't be able to prevent competitors from working on the same project.

    Part of the problem is that molecular biology moves so quickly that a copyright may be useless after a few years. A patent, however, can cripple a promising area of research. Given that most basic research is done by academics, and having read enough articles about scientists getting screwed by companies, I'm inclined to side strongly against gene patents.

    (* Except where required for publication in a journal.)