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Swiping Out Cancer

mhackarbie writes "Just read this article over on Wired about a cheap hand scanner which might be able to spot cancer tumors. It took only few seconds of reflection before I decided this could be the killer biotech app which is needed for the dot-bio boom everyone keeps predicting someday." We've mentioned this gizmo before.

42 of 128 comments (clear)

  1. Can you say... by craenor · · Score: 4, Funny

    Tricorder? ...I knew you could.

  2. What... by dysprosia · · Score: 2, Funny

    no flatbed cancer-scanners? I'm sure there'll be a market for them! ;)

  3. This is not biotech by stm2 · · Score: 2, Informative

    It won't be a biotech "killer app" since biotech companies are working on genomic and proteomic application. By definition, biotech involves altering DNA on organism (usually bacteria) and selling a protein or procedure derivated from it.
    This device seems promising, but can't be called biotechnology.

    --
    DNA in your Linux: DNALinux
    1. Re:This is not biotech by robslimo · · Score: 5, Informative

      Bullpuckey.

      Bio, a prefix meaning life/living organisms
      tech, short for technology.

      OK, we've got a handheld scanner that can be used to enhance/lengthen/improve a persons life. Seems like an application of techology to life/living organisms.

      Biotech it is.

    2. Re:This is not biotech by Lershac · · Score: 2, Funny

      For someone so hung up on the meaning of words... Just what does "derivated" mean?

      TROLL

      --
      Chuck
    3. Re:This is not biotech by stm2 · · Score: 2, Informative

      Hello Rob,

      I understand what you mean with bio=live tech=technology, so this would we biotech. But according to most biotech official definition, biotech is another thing.
      Look here:
      According to dupont (a industry leader)
      "is the application of scientific knowledge to transfer beneficial genetic traits from one species to another to enhance or protect an organism"
      According to the Biotechnology Industry Association:
      "The use of biological processes to solve problems or make useful products."
      This last is more broader, but it fundamentals is to use a biological process. IF the handheld scanner basic would be based on a bio function, ok, but it is electronic. It is used to monitor a bio process, but the device is based on an electronic principle.
      Look at the biotech companies websites (lot of them trades in NASDAQ), and look for their products, they don't offer what most slashdot reader call biotech.
      Trying to explian what biotech is to an slashdot reader is as hard as trying to explain to my biotech coworkers that hacking is not something evil :)

      --
      DNA in your Linux: DNALinux
  4. I'm sure it will do wonders for.. by 3.5+stripes · · Score: 4, Interesting

    Insurance companies as well.

    Go to your job interview, pee in this cup, swipe this in your mouth.

    In one simple step eliminate drug users, and possible insurance deadweights... Joy!

    --


    He tried to kill me with a forklift!
    1. Re:I'm sure it will do wonders for.. by xtal · · Score: 4, Insightful



      Insurance companies as well.

      Go to your job interview, pee in this cup, swipe this in your mouth.

      In one simple step eliminate drug users, and possible insurance deadweights... Joy!


      Those who subject to drug tests have nobody to blame but themselves for their proliferation to other industries like insurance. If nobody submits to a test, or a signifigant fraction of the exceptional workers refuse, a competitive advantage exists for those companies who do not test.

      The process of pre-employment drug testing is rare (and, I think, illegal) in Canada, and our country has not fallen apart as a result. I have no information to assume there is any difference in levels of drug addiction between Canada and the USA.

      Drug testing is easily remedied outside the courts if it truely bothers you. It seems most people are content to piss in a cup for a job. To each their own.

      --
      ..don't panic
    2. Re:I'm sure it will do wonders for.. by Pastis · · Score: 2, Interesting

      [OffTopic]
      You should read the latest Eric Schlosser book, "Refeer Madness: Sex Drugs and Cheap Labour". He mentions differences between Canada drug strategies and USA ones, at least regarding marijunana.
      [/OffTopic]

  5. Erm by TCM · · Score: 5, Funny

    Is it just me or does anyone else find using the words killer biotech app a bit.. unlucky? Keep that thing away from me!

    --
    Of course it runs NetBSD. BTC: 1NT7QvbetmANwaMzhpVL6
  6. The key is if it's better than current detection by Alkarismi · · Score: 5, Insightful

    As someone who has seen, at first hand, the horrors of undetected cancer, this could just the ticket.
    My Father died from cancer last year. He had a secondary tumor removed a year before, but the specialists who saw him could apparently not detect a primary. It was clear to us that there was one (he was degenerating), but current detection techniques, apparently, couldn't find it. An autopsy was conducted when he died, at which point extensive cancer was located.
    Part of the cure for cancer must surely be early, and accurate, detection. Let's hope this is part of it!

  7. Discovery Channel by Anonymous Coward · · Score: 5, Interesting

    Discovery Channel had a show not too long ago about trained dogs being able to -smell- cancer on test subjects.
    Not only would it not require development or be at the hands of some biotech CEO, but dogs have been shown to lower blood pressure in people.

    Think of it: Handheld Schnauzer.

    You could probably train basset hounds too, just so that PVP would have more material.

    1. Re:Discovery Channel by SkewlD00d · · Score: 3, Interesting

      Yeah, I remember that... it was very impressive. I believe that a dog has superior computational power and discrimination abilities that could easily be more accurate and reliable than some piece of technology. How much/hard would it cost to train a dog to do this? Imagine... if we have specialized dogs for certain functions... eventually will have purpose-bred species of animals/plants for very specific tasks (*cough* babel-fish :). Also, I remember something about a UV camera system for dermatologists. Btw, have you ever looked at your skin in a mirror w/ a black-light (CCUV flourescent), you can see differences in tissues in you skin not visible in white light.

      --
      The biggest trick the devil pulled was letting lawyers become politicians so they can write the laws.
    2. Re:Discovery Channel by bigpat · · Score: 4, Insightful

      Problem with dogs that are trained to sniff anything, be it drugs, bombs or cancer vs some man made technology is the inconsistency between dogs and dog trainers. Although, they may be more sensitive than any man-made device, they also have bad days and can get sick without their handlers noticing. Better to have a device that while not necesarily more reliable or sensitive, might be more easily tested for variations in performance. In other words, are dogs really going to be accurately tested every day to make sure their performance isn't slipping? But maybe a device can be tested more easily and regularly to ensure quality.

      So, why are dogs so heavily relied upon at airports and for other security. Because simply put, security doesn't need to be 100%, it is largely the deterrent that the dogs provide that provides the actual security. Knowing that these dogs are being used will deter the less serious drug smugler or terrorist from the attempt. But with something like cancer screaning you really have to have a high degree of certainty and invariability in order for it to be useful.

      So the reason dogs wouldn't be used is that they just add to the cost of diagnosis, but can't rule out cancer to a high enough degree, making additional more invasive diagnostic procedures needed anyway.

      If this electronic device can be 99.9% accurate at determining that a person doesn't have cancer when used properly, then you can then focus resources on those remaining. Which is better for those that are shown to be clear of cancer. But it also changes the economics for those devices that require greater capital expenditures, they are only economical when used on larger numbers of people, but if this screaning reduces those numbers of false positives, then a fewer number of truly sick people will be left paying for the more expensive machines. So either the number of expensive diagnostic machines will need to be reduced, the price will have to come down, or the cancer sick individuals will be charged more money.

  8. Progress by Duds · · Score: 3, Funny

    We now advertise dupes directly in the story to save your inevitable searches!

    Another slashdot timesaver * teeth glint *

  9. Arnt Microwaves on the body dangerious? by jellomizer · · Score: 4, Insightful

    The fact the thing gives off microwaves probably means that it wont be for normal consumer use. The advantage is that it can be so every doctors office can have one or more. Because of its size. But I can see some person so worried about cancer who scans themselves all the time until the microwaves give him cancer.

    --
    If something is so important that you feel the need to post it on the internet... It probably isn't that important.
    1. Re:Arnt Microwaves on the body dangerious? by G.+W.+Bush+Junior · · Score: 4, Insightful

      Has it even been shown that microwaves cause cancer? To the best of my knowledge there's no conclusive evidence. The reasoning behind it is shaky as well: "We all know that sticking your head in a microwave oven is bad for you... right?" Microwaves induce movement of water molecules (when its in liquid form). so does your stove... why should we fear this without any hard scientific evidence that it is dangerous?

      --
      "I don't know that Atheists should be considered as citizens, nor should they be considered patriots." -George H.W. Bush
    2. Re:Arnt Microwaves on the body dangerious? by Idarubicin · · Score: 3, Informative
      "We all know that sticking your head in a microwave oven is bad for you... right?" Microwaves induce movement of water molecules (when its in liquid form). so does your stove... why should we fear this without any hard scientific evidence that it is dangerous?

      This isn't because microwaves cause cancer--there still is no consistent corpus of evidence to support that hypothesis and there may never be--but rather because they cause heating. There are proteins within our bodies' cells that begin to denature at around forty degrees celsius. At or above this temperature (which actually isn't particularly warm), the proportion of exposed cells that die is a function of temperature and exposure time. (See, for example, James R. Lepock, "Protein Denaturation During Heat Shock" in Advances in Molecular and Cell Biology, Volume 19, pages 223-259, for an excellent survey of current thought on the mechanisms at work.)

      So microwaves are dangerous because they cause heating. Not only that, they can cause deep heating in localized hotspots. In other words, you may actually do damage to the brain, eyes, and other organs very quickly without having to burn through the layers on the surface first. (This is what makes microwaves more threatening than the stovetop. The heating elements don't burn unless you come into close contact, and they can't burn deeply without lengthy exposure.)

      --
      ~Idarubicin
  10. How about cancer-sniffing dogs? by blakespot · · Score: 4, Interesting
    It seems you don't need electronics to detect cancer, just man's best friend. Interesting stuff.


    blakespot

    --
    -- Heisenberg may have slept here.
    iPod Hacks.com
  11. Now they can use millions of the CueCat scanners by leoaugust · · Score: 2, Funny

    I am glad somebody found out what to do with these scanners.

    Hopefully now all those millions of CueCat http://ptech.wsj.com/archive/ptech-20001012.html scanners can be put to some use ....

    --
    To see a world in a grain of sand, and then to step back and see the beach where the sand lies ...
  12. cancer by Pompatus · · Score: 5, Insightful

    This is something that interestes me. My father died of cancer at the age of 56 and my mother survived it at the age of 44. I think I might have a high hereditary risk. The idea of cheaper detection methods is important. The cheaper it is to detect, the more frequently the tests will take place. Hopefully, this could become part of a yearly checkup.

    For the record, neither of my parents were smokers. I think I might know how I am going to die.

    --

    ----
    Squirrel ... It's not just for breakfast anymore
  13. Not convinced by pubjames · · Score: 4, Insightful

    Now, it would of course be great if this actually worked, but I have to say I am very sceptical.

    I find it difficult to believe that the system it uses will actually produce accurate results. The human body surely has lots of tissues in different structures and densities, and also of course there are lots of different types of cancer. Most importantly, you want to get cancers when they are small - tiny even. I find it hard to believe that this scanner could do that. If you've ever seen a small cancerous mole, for instance, you will understand.

    When we're dealing with stuff like cancer, 95% (say) accuracy isn't enough. False positives result in a lot of stress for people until they have proper tests. False negatives of course have even worse consequences.

    Complex problems don't have easy solutions. Cancer is complex.

    1. Re:Not convinced by nordicfrost · · Score: 4, Insightful
      False positives result in a lot of stress for people until they have proper tests. False negatives of course have even worse consequences.


      I have seen the hardships of a cancer patient, my mother, up close. After the operation was over and she was decleared cancer free, the nightmare began. The semi-annual check-ups. The false positive rate for these check-ups is amazinf. She has been checked 10 times the last 5 years and 8 out of ten times she was called back for confirmation of non-existense of cancer with all the fear you could imagnine. How can this device be any worse?

    2. Re:Not convinced by HeyLaughingBoy · · Score: 4, Informative
      When we're dealing with stuff like cancer, 95% (say) accuracy isn't enough.

      For many blood tests, 95% accuracy is considered excellent and essentially means it's 100% accurate for all practical purposes. hCG (pregnancy test) comes to mind. I doubt current single tests for cancer are any better.
      Hmmm... a quick googling reveals that current breast cancer methods are around 80% and a new PSA (prostate) test clocks in at 98% best case.
      I'd say 95% is pretty damn good.
    3. Re:Not convinced by stm2 · · Score: 2, Informative

      95% is excellent as you say. But pregnancy test, has more than 99% accuracy, since it is based on an monoclonal antibody mediated reaction.

      --
      DNA in your Linux: DNALinux
    4. Re:Not convinced by TheDredd · · Score: 2, Interesting

      A lot of people get cancer, in fact everybody, but you're body normaly prevents it from growing and destroying your body, that's why younger people are less likely to get cancer then older people, they have a much higher resistance.

      So I think this scanner will find all the cancers in your body, but it's up to the doctor to determine the evil/growing cancer, and of course make the appropriate decision

  14. Fantastic! This will come in eh...'handy' for: by madmarcel · · Score: 3, Insightful

    Here's a post about something a fair amount of /.ers will not be familiar with: BREASTS
    (we're talking hands-on experience guys, looking does not count ;^)

    What have (wonderful wonderful) female breasts got to do with a handheld cancer-scanner?

    Well...do you know how they check women's breasts for tumors currently? No? Well...

    It involved placing a single breast in a vice-like device, which is then TIGHTENED.
    (And yes, the device is made out of COLD metal ;) It is apparently also a fairly inaccurate method of detecting breast-cancer, but that is another story :o Then repeat process for the other breast.

    (I don't have this from first-hand experience, I am not a woman :)

    Now imagine if you could do the same with a little baton...

    "I wave my magic-stick and...voila!"
    (For godsake, don't take that out of context ;)

    Testicle-cancer in men is (also) often diagnosed too late. I do not know how they confirm that you have it (AFTER the physical examination) but I hope to god it does not involve a vice-like device :o
    Again, bring on the handheld scanner...

    BTW some poster mentioned that micro-wave radiation is dangerous...nope, not as far as I can establish...(read up on the HERF gun previously mentioned on /. )

    1. Re:Fantastic! This will come in eh...'handy' for: by Michael+Dorfman · · Score: 2, Informative

      >Testicle-cancer in men is (also) often diagnosed too late. I do not know how they confirm that you have it (AFTER the physical examination) but I
      > hope to god it does not involve a vice-like device :o

      A vice-like device? You should be so lucky.
      Confirmation involves a knife.

  15. Good, but not the killer app by AlecC · · Score: 2, Interesting

    It took only few seconds of reflection before I decided this could be the killer biotech app which is needed for the dot-bio boom everyone keeps predicting someday

    Sorry, I don't see it. It doesn't lead anywhere - it isn't the first of a class of devices. Obviously, if it works (lots of qualifiers in the article) it is an extremely good gadget. Many patients will benefit, and the inventors may well become justifiably rich. But apart from a sequence of improving models, all doing the same thing but steadily better, where does it lead to? It detects cancers - full stop. It detects them by detecting the nature of cncerous growth. So it won't do anything about anything else.

    I don't want to knock it. $30,000 is cheap enough for every doctors surgery, and therefore for routine use any time there is a worry. If it is simple enough and safe enough, I could see them going into gyms etc, so you have a cancer check along with your fitness check. Even an optional sevice in airport departure loinges to while away those boring hours. (Hey - integrate it with the bomb scanners - get a free cancer check as the price of being scanned for explosives. Paranoia in a worthwhile cause).

    --
    Consciousness is an illusion caused by an excess of self consciousness.
    1. Re:Good, but not the killer app by mhackarbie · · Score: 3, Interesting
      There are several reasons why I believe that it has potential as a killer application in biotech. Because it is an external hardware device, it bypasses a lot of testing and regulatory issues that are such a problem for drug development. Also, to improve the diagnostic problem, I think devices like this will ultimately be used in the home, and will generate lots of data over long periods of time. This will provide a lot of opportunity for software developers to create applications which can analyze the data, present it to the user in a useful way, and integrate it with other medical data. I believe that statistical analysis of tissue scan data of millions of people over a period of years or decades might enable a much more effective diagnosis.

      Getting a personal computer into the home was a critical step in the evolution of computer technology, because it brought millions of people into the development cycle. I think the same thing will be true for the evolution of medical technology.

      mhack

      --
      Building a better ribosome since 1997
  16. Sad by pubjames · · Score: 3, Interesting

    Sorry, people are rather interested in themselves, not in charity.

    Speak for yourself.

    In the USA over the last few decades a rather sad mindset has developed amongst certain people. That is that selfishness is normal, natural even. People use this to justify their selfish behavour, or that of the organisations they work for. It is very sad.

    Cancer can act as a metaphor for this type of thinking. Our human bodies are made up of millions of individual cells co-operating and working together. A cancer occurs when a cell becomes defective and no longer lives in harmony with the others.

  17. But it hasn't been peer reviewed! by PelagicArgosy · · Score: 5, Informative

    "Experts will remain cautious until a study on TRIMprob's abilities has been examined in a peer-reviewed medical journal."

    and from the earlier BBC article:
    "The results have yet to be accepted for publication in a major medical journal - and the device will not find favour in hospitals elsewhere until they are."

    This is the key point - without peer review, there's no way of verifying the claims of a company that is obviously in marketing mode.

    Searching Medline for "Tissue Resonance InterferoMeter Probe" or "TRIMprob" turned up ZERO matches. Without good evidence, there is no reason to take this seriously as other than marketing fluff.

  18. Wouldn't it be great if... by mikeophile · · Score: 4, Funny
    this technology was incorporated into cell phones?

    A quick scan and you could rest assured that your phone wasn't giving you cancer.

    Until it does, that is.

  19. That's easy where I'm from. by k0de · · Score: 5, Insightful

    I agree, and not just for cancer. I live in Canada and though health care is virtually free, not being able to 'buy the best advice' leaves me doubting every diagnosis, and in many cases rightfully so.

    This type of device, if extended for other types of detection, could be exactly what 'Dr. Dad' needs to ensure the family is in general good heath without having to rely on the shady advice of under skilled or under paid health care staff.

    --
    I'm wrong and so are you.
  20. dot everything! by nfotxn · · Score: 2, Insightful

    "dot-bio boom"?! There's an over-simplified buzzword raped straight from CNN.

    --

    _nfotxn

  21. Misinformation. by Marc2k · · Score: 4, Informative

    You're only making things worse. You misquoted (perhaps intentionally) to further your definition in hopes that no one would find the Dupont site. The actual line you're quoting, sans elipsis, states, "Transgenics (often referred to as biotechnology) is the application of scientific knowledge to transfer beneficial genetic traits from one species to another to enhance or protect an organism."

    They are clearly talking about the field of transgenics, which is what you called 'biotechnology', they were merely stating that it is often called biotechnology, but with the implication that biotech refers to a much larger spectrum.

    Even further, if you would have followed the link to the Biotechnology Industry Organization (BIO)'s glossary, you would have found that they describe biotechnology as, "Biotechnology -
    The use of biological processes to solve problems or make useful products." under which the product in question would surely fall.

    --
    --- What
  22. But what we really need... by Snafoo · · Score: 3, Interesting

    Is something like this for STD's. Oh come on, admit it --- condoms suck, and not in that fun way. Wouldn't you rather just tricoder her nether-regions?

    --
    - undoware.ca
  23. Article smells of hype by djh101010 · · Score: 2, Insightful

    The article opens with comments about "40 minute MRI and CAT scans", and "the narrow tube of the MRI scanner". It proceeds to state that an MRI costs "$1000 of the patient's money". While the first two were maybe true a decade ago, the days of even a 20 minute MRI scan are long gone. The medical imaging business is half about diagnostic quality, and half about patient throughput.

    By speeding up the scans as they've been doing since day one, they get more patients through during a day, allowing the scanners to be more profitable, and for the costs to go down. The $3,000,000 figure is awfully high for even a high-end MRI scanner these days.

    This might very well be an interesting, promising device. But, making it look as if it's really good, by presenting deceptive information about the current options, is a huge red flag as far as I'm concerned.

    If it's really a useful device, present it as it is - don't lie about the other technologies. If it's that superior, the marketplace will find it and respond accordingly.

    1. Re:Article smells of hype by CompCons · · Score: 3, Interesting

      Check out this company....they have a way of detecting breast cancer that no one is using...works better than Mammogramms or Sonograms and it's cheaper than all of them. I think it's time we started paying attention to the new technology instead of just assuming that the old stuff works fine. Alot of people are dying of cancer and the numbers are only rising.

  24. issue of false-positives by peter303 · · Score: 2, Insightful

    The case of "MRIs on demand" shows the problem of ambiguous medical tests. There are firms all around the country that will perform and interpret a thorac MRI for as little as $500. Typically they find find dozens of "anomalies", that are probably harmless. However, it may cost thousands to track these down, including in some cases biopsies. Especially since the people who voluntarily solicit these MRIs are worry-worts in the first place. Medical economists suggest that test with lots of false-positives are economically counterproductive in an already expensive medical system.

  25. Re:cancer by The+Clockwork+Troll · · Score: 2, Funny
    Oranges, for example, can be stored for a few years before appearing on the shelves.
    ah yes, that dreaded biological weapon, Aged Orange.
    --

    There are no karma whores, only moderation johns
  26. Precision and recall by blahedo · · Score: 2, Insightful

    Different forms of medical devices have different requirements for precision---that's the percent of things they report that are correct---and recall---that's the percent of things they are supposed to find, that they do find. Before this could replace an MRI as a primary diagnostic tool, it would need to have 100% recall. Precision is less important, because if you do get a false positive, you can go in for further testing (which is not to diminish the stress and fear induced by false positives).

    In the article the experts comment that it can't replace MRIs yet with the reported accuracy rate, which is true. What it *can* do is become a routine part of a physical. Once the wand is bought, it sounds like using it is essentially free (well, they have to occasionally replace the batteries!), so there's no reason not to just use it all over the place. And what *that* does is make it more likely that we'll detect tumours early, before we would have any reason to suspect a problem otherwise.

    On the problem of false positives, btw---a lot of that can be mitigated by a good doctor. When a false positive is possible, the doctor needs to explain that, exaggerating its possibility, to reduce the stress in the meantime. My mom went through that once; it turned out that she was just unusually athletic and the more muscular tissue set off the sensor! But those three days sucked. Had the doctor said, "look, this is probably nothing, we just need to run another test", it's not nearly as bad.

    --
    ``This, too, shall pass.'' ---Eastern proverb