Smallpox From The Past

An anonymous reader submits "Earlier this year, librarian Susanne Caro was looking through an 1888 book on United States Civil War medicine and discovered a small envelope labeled 'scabs from vaccination of W.B. Yarrington's children' and signed by Dr. W.D. Kelly, the author of the book. After a bit of research, she realized they might be smallpox scabs used in early live vaccination methods and contacted various officials including the Centers for Disease Control and Prevention. The CDC was excited by the find, because it gives them an untreated specimen from over a century ago, and a chance to look at the disease's evolution. Although the FBI had concerns that the smallpox may have been planted in the book, most of the researchers believe the scabs are too old to be dangerous, and they fear they may not even be able to yield live smallpox."

Comments

Virus are on Border of living and Dead Matter ...

[leoaugust]

1. virus -- ((virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein)

In viruses, which represent the border between living and dead matter, there are simpler aggregates between nucleic acids and proteins. A virus can be said to be genetic material without a cell of its own, and the structure of viruses can provide clues to the more complicated organisation of the hereditary material in higher organisms.

Virus represent the border between living and dead matter. I thought that it meant that when the virus came across a host cell it could inject its DNA and multiply and that is why it is living , and when it didn't it just lay dormant i.e. it was dead matter. Wasn't the whole premise of Jurrasic Park based on this notion ?

But in the article it says ....

Several years ago in Kentucky, she said, a construction crew unearthed a metal coffin containing the mummified corpse of an apparent smallpox victim that researchers traced to the mid-1800s. The CDC checked the tissue for live virus and came up empty.

There's also a slim chance, researchers say, that the scabs could yield live smallpox virus -- believed to reside in only two laboratories in the world -- and provide valuable information on the deadly plague.

If the virus is nothing but the DNA and a protein coating around it, why are the people wanting it to be live ?

Am I missing something ? What am I missing ?

Probably not smallpox virus anyway

[KFW]

AIAAD (Actually, I am a doctor). In fact, my specialty is Infectious Diseases.

By 1888 vaccination against smallpox using cowpox or vaccinia virus was a common practice, as opposed to "variolization" (inoculation with actual smallpox virus, aka variola virus), since the former was so much safer. This is touched on only briefly in the Washington Post article. So even if there is viable virus in the scab, it may not be smallpox. For reference see the first part of this chapter.

>K