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Smallpox From The Past

An anonymous reader submits "Earlier this year, librarian Susanne Caro was looking through an 1888 book on United States Civil War medicine and discovered a small envelope labeled 'scabs from vaccination of W.B. Yarrington's children' and signed by Dr. W.D. Kelly, the author of the book. After a bit of research, she realized they might be smallpox scabs used in early live vaccination methods and contacted various officials including the Centers for Disease Control and Prevention. The CDC was excited by the find, because it gives them an untreated specimen from over a century ago, and a chance to look at the disease's evolution. Although the FBI had concerns that the smallpox may have been planted in the book, most of the researchers believe the scabs are too old to be dangerous, and they fear they may not even be able to yield live smallpox."

18 of 211 comments (clear)

  1. Interesting by shawnywany · · Score: 5, Funny

    Sounds creepily like the beginning of a Robin Cook novel...

  2. scabs by Graspee_Leemoor · · Score: 5, Funny

    About the only time you will find scabs in a book and be excited about it. Mostly you'd say "Ok, I'm only going to buy NEW from now on".

    graspee

    1. Re:scabs by timepilot · · Score: 5, Funny

      Yeah but they would get some hairy negative feedback.

    2. Re:scabs by Anonymous Coward · · Score: 5, Funny

      "Horrible eBayer, gave my whole family smallpox, DO NOT RECOMMEND!!!!!!!!!!!!"

  3. Watch those libraries!! by Fruny · · Score: 4, Funny

    One more reason to have the government tightly control what books you check out.
    Libraries are a breeding ground for terrorists, I tell you.

  4. What Could Happen by hao2lian · · Score: 5, Funny

    Hey, are these raisins? *munch*

    --
    Pelé!
  5. In a freezer? by InfiniteWisdom · · Score: 5, Funny

    From the article:
    the envelope rests in a freezer at the Centers for Disease Control and Prevention in Atlanta, awaiting a battery of tests.

    Yes, after lying in a library book for 115 years I can see why is important that it be frozen now.

  6. It's like a time capsule by mcc · · Score: 4, Funny

    What a wonderful idea for a time capsule that would be. Create a time capsule to be opened in hundreds or thousands of years and place in it some of the diseases which may have died off by then and which the generations of the future will not have had the chance to enjoy.

    Infectious disease: The gift that keeps on giving.

  7. Virus are on Border of living and Dead Matter ... by leoaugust · · Score: 4, Interesting

    1. virus -- ((virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein)

    In viruses, which represent the border between living and dead matter, there are simpler aggregates between nucleic acids and proteins. A virus can be said to be genetic material without a cell of its own, and the structure of viruses can provide clues to the more complicated organisation of the hereditary material in higher organisms.

    Virus represent the border between living and dead matter. I thought that it meant that when the virus came across a host cell it could inject its DNA and multiply and that is why it is living , and when it didn't it just lay dormant i.e. it was dead matter. Wasn't the whole premise of Jurrasic Park based on this notion ?

    But in the article it says ....

    Several years ago in Kentucky, she said, a construction crew unearthed a metal coffin containing the mummified corpse of an apparent smallpox victim that researchers traced to the mid-1800s. The CDC checked the tissue for live virus and came up empty.

    There's also a slim chance, researchers say, that the scabs could yield live smallpox virus -- believed to reside in only two laboratories in the world -- and provide valuable information on the deadly plague.

    If the virus is nothing but the DNA and a protein coating around it, why are the people wanting it to be live ?

    Am I missing something ? What am I missing ?

    --
    To see a world in a grain of sand, and then to step back and see the beach where the sand lies ...
  8. Re:Virus are on Border of living and Dead Matter . by Slowping · · Score: 4, Informative


    If the virus is nothing but the DNA and a protein coating around it, why are the people wanting it to be live ?

    Am I missing something ? What am I missing ?


    They are probably referring to whether or not the DNA information is sufficiently in-tact. If the DNA is too far destroyed, the virus probably won't be able to reproduce itself even after infecting a live cell.

    --
    (\(\
    (^.^)
    (")")
    *beware the cute-bunny virus
  9. "Live" virus by porkchop_d_clown · · Score: 4, Informative

    In this context, "live" virus is able to infect and reproduce. "Killed" virus has been damaged to the point that it cannot infect a cell. Hence the concern over using "live" virus vaccines - the vaccines use a damaged or weakened virus that the body can easily defeat - but occasionally a few full strength particles get through and trigger the disease instead of vaccinating against it. "Killed" virus vaccines use fragments of destroyed viruses, ensuring you can't get sick from them, but possibly not as effective as the live kind.

  10. Re:uhh by Anonymous Coward · · Score: 5, Insightful

    Actually, they were worried the story was
    a hoax by someone who wanted to create fear
    and panic.

    As you might recall, after the US was hit with
    a bioweapons attack (resulting in numerous
    deaths, and the shut down of the U.S. Senate
    offices), it become popular for people to
    "copy cat" the weapon. Soon, people were
    sending packets of white talc power in the
    mail with threatening notes, all in hopes of
    causing a panic and shutting down a business
    for a few days.

    As we've gotten used to this sort of ruse,
    and developed technologies to detect anthrax
    spores, the people trying to spread panic have
    gotten more clever.

    Consider, for example, how hard it would be to
    create panic by sending a note through the mail
    claiming that the envelope contained small
    pox. Since small pox is tightly controlled,
    and highly infectious, it's unlikely a group
    (other than a government) has a sample of the
    virus. So the hoax would quickly unravel.

    A clever person who wanted to create a plausible
    story about how a small pox virus came to be
    found in a public space might have to work
    harder. For example, they could make up a
    story about old medical samples, museum equipment,
    etc.

    And so in this case, it's entirely reasonable
    for the FBI to question the origin of this
    envelope. No, I don't think they started
    out by saying "This was planted by Al Queda."
    Instead, they started with a skeptical
    line of questions: who had the book? was it
    ever check out before? where was it kept?
    who had access to this text? is the person
    claiming to make the find a real librarian?
    etc.

    I think in this case, you, my friend, are the
    one who jumped to conclusions about the
    conduct of the FBI. Indeed, it would seem
    that your post exhibits the sort of haste
    and rush-to-judgement that you seek to
    condemn.

  11. Misleading statement in article by mesocyclone · · Score: 5, Insightful

    There's also a slim chance, researchers say, that the scabs could yield live smallpox virus -- believed to reside in only two laboratories in the world

    Only the naive believe that live smallpox exists in only two labs in the world. A more accurate statement in the article would have been "only legally allowed in two labs in the world."

    There is strong reason to believe that North Korea has the virus. France is also believed to have it. Iraq may have had it up until recently, as it was endemic in the region in the late sixties, and just a few scabs in a refrigerator would have been enough. It used to be common practice for scientists and doctors to keep a bit of smallpox in the fridge when they gathered it from patients. Hence there could be samples, possibly not even labelled or known to the owners, in a number of places in the world.

    One reason that the plan to destroy all stocks at the CDC and the official Russian lab was the realization that rogue countries probably had the virus, and hence destroying it would damage future defense attempts.

    Furthermore, the USSR and later Russia maintained stockpiles of 20 tons of weaponized smallpox in the eighties (authorized by Gorbachev) and probably to the present, and loaded it into missile warheads. Furthermore, a number of their scientists have since emigrated to other countries. In 1994 a number visited North Korea for unknown reasons. One former Soviet BW officieal entered into a deal with Iraq to sell 5000 liter fermenters.

    And then we have accidental discoveries like these scabs. Smallpox can survive in scabs for a long time, although >100 years is stretching it.

    --

    The only good weather is bad weather.

  12. Re:Bioweapons will be used in WWIII (2006-) by mesocyclone · · Score: 4, Funny

    It's a widely believed fact that bioweapons and extensive use of tactical nuclear weapons will be used in WWIII that is due to begin in 2006-2007.
    Russia, China and the Arabs will unite. New York will be devastated by two small nuclear devices and while USA isolates itself to deal with the trauma, China invades Asia and Russia pushes into Western Europe.


    Could you pin down the dates a little more, old chap? I need to get my planning in order and know when to go hide.

    Thanks!

    --

    The only good weather is bad weather.

  13. From strength to strength by Doc+Ruby · · Score: 4, Funny

    Don't worry, this is the FBI which has made short shrift of Osama bin Laden, singlehandedly captured Saddam Hussein, cornered the Anthrax Mailer, cleverly foiled the 9/11 planebombings on advance intelligence, have kept Chinese industrial spies away from our tech secrets, has won the drug war, busted the thieves at Enron, WorldCom, Global Crossing, Arthur Anderson, and the rest. They found the malicious Bush leaker who blew CIA agent Plames cover in Niger, discredited the 16 State of the Union words about the imaginary African uranium bound for Iraq, preempted Iranian and North Korean nuclear bombs. They nabbed the 2000 election vote riggers, and are already jailing the criminals at the top of the 2004 eVote insecurity debacles. If they think something is scary, we should all bow our heads in fear, and double their budget again. If it were possible to promote the FBI chief, we would; instead, we'll just have to settle for the Patriot Act, which dissolves that archaic Bill of Rights which was just getting in the way.

    --

    --
    make install -not war

  14. Captain Obvious strikes again! by mabu · · Score: 4, Funny

    the FBI had concerns that the smallpox may have been planted in the book

    In a related story, the authorities are now scouring libraries coast to coast to find the book entitled, "Where I Am Hiding" by Osama Bin Laden.

  15. Re:uhh by mabu · · Score: 4, Funny

    Actually, they were worried the story was
    a hoax by someone who wanted to create fear
    and panic.


    In addition to "Fair and Balanced", I believe Fox News has "Fear and Panic" copyrighted. Watch yourself or you could get sued.

  16. Probably not smallpox virus anyway by KFW · · Score: 5, Interesting

    AIAAD (Actually, I am a doctor). In fact, my specialty is Infectious Diseases.

    By 1888 vaccination against smallpox using cowpox or vaccinia virus was a common practice, as opposed to "variolization" (inoculation with actual smallpox virus, aka variola virus), since the former was so much safer. This is touched on only briefly in the Washington Post article. So even if there is viable virus in the scab, it may not be smallpox. For reference see the first part of this chapter.

    >K