Human Gene Count Slashed

Posted by samzenpus on Wednesday October 20, 2004 @03:39PM from the half-the-human-I-used-to-be dept.

jd writes "The estimate for the number of genes in human genetic code has been savagely revised downwards. The new estimate, of between 20,000 to 25,000 genes is marginally less than the 27,000 for the Arabidopsis, a flowering plant in the mustard family. Earlier estimates had placed the number of genes at around 44,000 - or even as high as 100,000. Eric Lander of the Broad Institute in Cambridge, Massachusetts is quoted in the CNN story as saying that the number of genes isn't as crucial as how they are used." Read on for more, below.

jd continues: "This has the potential for making life extremely interesting for genetic engineers, given that both individual genes and interactions between genes must be proportionately more complex, in order to get the same level of complexity out. Half the number of genes equates to twice the information encoded in forms other than discrete physical blocks of code.

There is no mention in the article of a story running in 2002 of genetic therapies unexpectedly causing cancer, although if you now factor in the increased complexity of interactions, it is possible that such side-effects can be better understood and therefore prevented. The new estimates, therefore, are more than just idle curiosity but have the potential for impacting how the science is approached."

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