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HIV Immunity Gene Found In Rhesus Monkeys

Stile 65 writes "According to the BBC, the National Institute for Medical Research has isolated a gene in rhesus monkeys that makes them immune to HIV. Amazingly, 'only a single change to the human [version of the] gene is needed to enable it to block HIV infection.' It's a very different approach to treating HIV infection from the potential vaccine developed in Brazil and described earlier on Slashdot."

6 of 81 comments (clear)

  1. It may only be a "single change"... by Atrax · · Score: 4, Insightful

    ... but it sounds from the article like the actual practicality of making that change is some way off. I quote:

    it is important to stress that any therapeutic benefits that may arise from this research are unlikely to be felt for many years.

    "This type of gene therapy would involve removing white blood cells from patients, cloning them, and altering their genetic make-up before reintroducing them to the patient on an individual-by-individual basis.

    "Although it is theoretically possible, this approach is unlikely to be practical or cost-effective with currently available technologies."


    It sounds to me like this would be a rather arduous process to go through, and given the scale of the epedemic that means, effectively, no major impact. The only effective solution is likely to be a cheap, easily admistered, relatively safe vaccine.

    What would have an impact would be for religious leaders worldwide to withdraw their objections to birth control and actually promote condom use. Likewise better funding for medical facilities in overstressed third-world location would prevent infection via needle re-use, as would an educated approach to drug addiction, rather than simply pushing the issue underground.

    there, three easy steps to minimise the spread, while the clever guys work on an actual therapy.

    --
    Screw you all! I'm off to the pub
  2. Cure for AIDS consequences by crow · · Score: 2, Insightful

    Not to suggest that we shouldn't cure AIDS, but eliminating HIV as a threat might have some unintended consequences. Would infection rates for other STDs jump as people stopped worrying about condoms? I expect that any such cure will need to be accompanied by a major STD education campaign.

  3. Give us all the same genes by roseblood · · Score: 3, Insightful

    and soon we will all have the genetics that make us immune to all diseases known to man. Then, when a disease unknown to man arrives it can get us all at once, for genetic variation would be engineered out of us. BAD IDEA. Get us a vaccination, not gene modification.

    --
    There are lies, damned lies, and statistics.
    1. Re:Give us all the same genes by gl4ss · · Score: 2, Insightful

      well.. what if you can't have a vaccination.

      and this is the answer. and you need it.

      would you use it or not?

      though that's all MOOT: how about a little RTFA? ""In theory, it should be possible to take cells from an HIV-infected individual, make them resistant to HIV infection with the modified gene and reintroduce them into the patient. These cells could then block progression to Aids."

      insightful my ass

      --
      world was created 5 seconds before this post as it is.
  4. How to get a cure for AIDS: by Matt+Clare · · Score: 5, Insightful

    The same way we got a treatment for not being able to get an erection: make sure it affects a lot of rich, white, American men. We'll have a cure in no time!

    I joke, but many a true hath been spoke in jest.

    --
    .\.\att Clare
    1. Re:How to get a cure for AIDS: by Anonymous Coward · · Score: 2, Insightful
      make sure it affects a lot of rich, white, American men

      I've often heard people complain about 'evil' drug companies not spending enough on AIDS research, or charging too much for their drugs. I'm sad to say that if I was a drug company, I wouldn't touch AIDS vaccines/cures with a ten foot pole. Why? Because as soon as I spent a few billion in research to develop and test a drug (and many failures along the way), everyone will demand that I give it away for free to anyone who wants it.

      Yeah, maybe I'm a stingy bastard, but making cures for diseases that mainly harm poor people in other countries is a sure way to go bankrupt. Bankrupt drug companies do not produce any more drugs. More people suffer and die as a result.

      So how do we fund AIDS research? Government funding is the only way to do it. I think there should be an international bounty for finding a cure or vaccine for HIV/AIDS. Get the bounty up to $20-50 billion, and promise to give the entire sum to the first company to produce a viable cure or vaccine. The company will not be allowed to patent the drug, so anyone can produce it and sell it as cheaply as possible.