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Do You Want to Live Forever?

Jamie McCarthy writes "In 1918, Gunnery Sergeant Daniel Daly inspired his weary men to attack by yelling, 'come on, you sons of bitches, do you want to live forever?' But how would the world change if we could? This month's Technology Review introduces us to the computer scientist, and self-taught biologist, Aubrey de Grey, who thinks immortality could be within our grasp by 2030. Thinking like an engineer, he's broken aging down into seven specific problems, like cell atrophy and mitochondrial mutation, which he believes can all, in principle, be solved. And he has good reason to think those seven are the only 'bugs' standing in the way of a thousand-year lifespan. De Grey is clearly both a genius and a little nuts, but I'm not sure in what proportion..."

4 of 1,334 comments (clear)

  1. Re:Doom for Social Security by bogie · · Score: 4, Informative

    Actually that's 2042 not 2031.

    http://www.ssa.gov/OACT/TRSUM/trsummary.html

    "This is one reason that SS is fundamentally flawed."

    Your take, not fact.

    Btw I'd like to point out that the reason most people need social security is because the most productive years of their lives are behind them and they need it because they have no more earning power. If you were "immortal" you could just keep working and wouldn't need SS.

    --
    If you wanna get rich, you know that payback is a bitch
  2. Re:Nuts, but also well suited for the task by Holi · · Score: 5, Informative

    Daly dreams of being on the cover of Time magazine

    No,
    Daniel Daly is dead and buried in Cypress Hills Cemetary. Daly was arguably the greatest marine of all time and the man behind the famous quote. Aubrey de Grey is the self taught micro-biologist who may or may not "dream of being on the cover of Time magazine".

    --
    Sorry, teleporters just kill you and then make a copy. A perfect, soul-less copy.
  3. Re:Doom for Social Security by Catbeller · · Score: 4, Informative

    " The Social Security System will fail Shortly after 2031."

    No. An utter lie.

    The New York Times:

    A Question of Numbers
    By ROGER LOWENSTEIN

    Published: January 16, 2005

    THE CONSERVATIVE NEW DEAL

    In 1938, the Social Security Act was only three years old, but its future was already very much in doubt. Conservatives claimed it would bankrupt the nation, and independent critics argued that the way it was financed amounted to ''financial hocus-pocus,'' as one editorial in The New York Times put it. President Franklin D. Roosevelt defended the program, said by a cabinet member to be his favorite, with some of his trademark oratory. ''Because it has become increasingly difficult for individuals to build their own security,'' the president told a national radio audience, ''government must now step in and help them lay the foundation stones.''

    Social Security did become the cornerstone -- not only the biggest government entitlement plan but also the most universal, the most popular and the most enduring. But the debate over Social Security never ended. Barry Goldwater wanted to repeal it; Milton Friedman wrote in 1962 that it was an unjustifiable incursion on personal liberty; and David Stockman, the budget director who personified Ronald Reagan's efforts to shrink the federal government, tried to take a hatchet to Social Security, which he called a ''monster.''

    But in this 70-year struggle, no other conservative has ever come as close to transforming the program as George W. Bush. He is making Social Security reform, including a partial privatization, a centerpiece of his second term. If the most ardent ideologues have their way, such a reform would be a first step toward a wholly new approach to retirement security -- one that would set aside the notion of collective insurance and guaranteed minimums for that of personal investing and responsibility.

    This could do more to reverse the New Deal, and even the Great Society, than Goldwater, Stockman and Reagan ever dreamed of. ''We call it a conservative New Deal,'' says Stephen Moore, author of ''Bullish on Bush: How George W. Bush's Ownership Society Will Make America Stronger.'' In Moore's words, it will be a fundamental shift ''from an entitlement society to an ownership society.'' The key to this transformation, according to a generation of conservative thinkers and crusaders, is reducing the size and changing the nature of Social Security, which now pays benefits of half a trillion a year, and which will only grow bigger as America grows older.

    The campaign to privatize has not only been about ideology; it has also focused on Social Security's supposed insolvency. Moore's book calls Social Security a ''Titanic . . . headed toward the iceberg'' and a program ''on the verge of collapse.'' A stream of other conservatives have bombarded the public, over years and decades, with prophecies of trillion-dollar liabilities and with metaphors intended to frighten -- ''train wreck,'' ''bankruptcy,'' ''cancer'' and so forth. Recently, a White House political deputy wrote a strategy note in which he said that Social Security is ''on an unsustainable course. That reality needs to be seared into the public consciousness.''

    The campaign is potentially self-fulfilling: persuade enough people that Social Security is going bankrupt, and it will lose public support. Then Congress will be forced to act. And thanks to such unceasing alarums, many, and perhaps most, people today think the program is in serious financial trouble.

    But is it? After Bush's re-election, I carefully read the 225-page annual report of the Social Security trustees. I also talked to actuaries and economists, inside and outside the agency, who are expert in the peculiar science of long-term Social Security forecasting. The actuarial view is that the system is probably i

  4. This guy seems like an idiot by Noco · · Score: 4, Informative

    I have a degree in Biochemistry, Cellular and Molecular Biology. I used to work in a Genetics research lab as well. Now, I'm no Cambridge Scholar, but I'm not stupid. But unless I'm missing something, this guy has basic points wrong in most of his 7 points.

    Eliminating telomerase is not bad, and a way to reduce/eliminate cancer. Telomoerase is essential for Germ Cells, i.e. sperm and egg cells. It seems unlikely to be able to eliminate it in all cells but these.

    Cancer cells don't need telomerase. There are countless avenues to cancerous cell growth.

    Stimulation cell growth is good and necessary. Cell growth in the brain could be extremely problematic. The brain is a living, connected system. The connections are what make the brain what it is. Unlike computeres with fixed hardware and variable software, the brain is variable in both. The electrical patterns can change as well as the paths the patterns take. Essentially, they are insepearable. The addition of new cells, with no way to control their connectedness would not aleveate the problems of cellular degredation and loss.

    Extrecellular protein linkages are unique. Biology is extremely effecient at its use of chemical compounds, structurally. Our knowledge of protein strcuture is limited, due to the limitiations we have of computational modeling due to limited computational abilities. That he should think that extracellular proteins show unique linkages seems hubristic. It is possible we don't understand all protein interactions yet.

    Cell growth can be stimulated naturally. Here, even a passing comment has errors. Muscle cells are stimulated to divide by excercise. No! Excercise increases the size of muscles by stimulating an increase in production of muscle fiber proteins. More proteins cause a cell to be larger, and thus the overall muscle to be bigger. Thus excercise increases the size of muscles, not the number of cells. This is basic biology.

    Mitochondrial proteins will work in the nucleus.While most cells in the world use a universal genetic code, some vary specific cells do not fully share the code's universality. Some non-eukaryotic cells and mitochondria. (It is interesting to note that mitochondria are thought to be descendended from symbiotic non-eukaryotics cells themselves.) I don't know off the top of my head if these proteins will work with both codes, but it seems likely that even if the nucleus can produce the raw protein, the proper folding, transport, and ultimate use of the proteins might not occurt since they are not where they need to be, namely inside the mitochondria. Only native proteins might be functional.

    Again, I might have too simple an outlook or be completely incorrect, but it seems that there are basic concepts of biology that conflict with de Grey's ideas.