Tetris DS - First Nintendo DS Homebrew Game
gbaemufan writes "Desktopman released a Tetris clone for the Nintendo DS, at the moment the only way to play it is via a passthrough device until a homebrew DS cart is released."
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The GBA cartridge is used to hold the code. It runs the code completely in DS mode after booting it up.
Well, so far the guys at DSDev have managed to get the DS's "Play Downloaded Game" feature to display a title and icon of their choosing. I'm not aware of the particulars, try joining the forum and going along.