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Study Shows One Third of All Studies Are Nonsense

SydShamino writes "CNN has a report on new research to confirm claims made in initial, well-publicized studies. According to the new study, about a third of all major studies from the last 15 years were subsequently shown to be inaccurate or overblown. The study abstract is available."

33 of 391 comments (clear)

  1. Mathematically Challenged by fembots · · Score: 2, Insightful

    My apology in advance for being a MC-person, but if 1/3 of the studies are inaccurate, which means this study can be 1/3 inaccurate, does it mean that the actual inaccuracy is 1/3 * 2/3 = 2/9 of all major studies are inaccurate?

    1. Re:Mathematically Challenged by DavidHumus · · Score: 2, Insightful

      Actually, this isn't a bad guess.

      The text of the article does not suppport the 1/3 bad claim exactly. Instead, it reports that 1/6 of initial reports are subsequently contradicted and another 1/6 are subsequently only weakly supported.

      Estimating from this range, the true number is probably somewhere in between, say 22.2% (=2/9) which is between 16.7% and 33.3%, or 24.5% which is the aveage of these?

  2. Nonsense! by Speare · · Score: 2, Insightful

    Since when is "inaccurate" or "overblown" nonsense? That's what science is: study something, make a theory, and just about dare someone else to prove it wrong, because that's what makes for a better theory.

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    1. Re:Nonsense! by GileadGreene · · Score: 5, Insightful

      Yes, but this wasn't talking about surveys with leading questions. TFA was talking about clinical studies published in medical journals like JAMA and the New england Journal of Medicine.

    2. Re:Nonsense! by Nasarius · · Score: 2, Insightful

      Exactly. Of course a good portion of studies, even when conducted properly, produce inaccurate results. That's the whole purpose of peer review; doing further research tends to filter out the bad stuff.

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    3. Re:Nonsense! by GileadGreene · · Score: 4, Insightful
      Again, had you RTFA you would know that they weren't talking about 'weak' papers, they were talking about papers and studies that were later contradicted by several other studies. Their principal message was that we need to be careful about accepting a brand new study at face value, before anyone has had a chance to try replicating the results. Most anybody versed in science would know this. But many in the media and the general public apparently don't. Hence the article.

      The Slashdot summary of this particular article is more than a little misleading and sensationalist.

    4. Re:Nonsense! by biobogonics · · Score: 4, Insightful

      TFA was talking about clinical studies published in medical journals like JAMA and the New england Journal of Medicine.

      At one time the NEJM was considered a "gold standard" in publishing medical research. IMO, that's no longer true. I do believe that journals are no longer as careful about what they publish. [Rhetorical question- why did Marcia Angell leave as editor of the NEJM?]

      While we do expect "science" to eventually verify or refute claims made in scientific studies, I do not remember such a high percentage of studies being "overturned", as the lawyers would say. [Of course I am susceptible to "recall bias. :-)!]

      Along with journals more willing to print research, I do believe that the quality of research itself has worsened. [I've seen first hand some of the "fun and games" that take place in academia. That's one reason I'm no longer there!]

      In addition, the public's hunger for news about health and lifestyle and the media's need for sensationalism have fueled a news feeding frenzy. I doubt that the public or the news media are really capable of judging the worth of clinical studies. I don't think the public or the media understand the medicine or science involved nor do they actually know how to evaluate research on scientific, methodological or statistical grounds.

      I get really peeved when I see some study touted on TV that reports a 10% reduction in some disease supposedly caused by modifying some risk factor. Without seeing the confidence interval bouding this estimate of risk, I'm not willing to say the effect is real. As a rule of thumb, I was taught to view with skepticism any study that does not halve or double the relative risk attributed to a risk factor.

  3. Studies inaccurate but not completely bogus by LucidBeast · · Score: 1, Insightful

    I think it states that most studies have inaccurate or overblown results not that 1/3 of studies are completely off.

  4. Nonsense by Coyote399 · · Score: 2, Insightful

    Just because a study has inaccuracies doesn't mean the whole thing is nonsense.

  5. Falsifiability. by Tackhead · · Score: 2, Insightful
    > According to the new study, about a third of all major studies from the last 15 years were subsequently shown to be inaccurate or overblown.

    According to a recent study involving 100 clones based on DNA fragments of Karl Popper, a statistically significant number of the clones agree that this is pretty goddamn good result, considering that that's how science is supposed to work.

    You know - that silly process whereby you make a falsifiable claim, run an experiment, report your results, and encourage others to add to the store of scientific knowledge by attempting to falsify your original hypothesis?

    1. Re:Falsifiability. by cookie_cutter · · Score: 4, Insightful
      I agree with what you're saying, but that is not, exactly, the issue here.

      This isn't about hypotheses turning out to be false, it's about experiments which produce bad data, seemingly, at there release, supporting bad hypotheses.

      While even a good scientist can come up with wrong hypotheses, no good experimental scientist should be creating experiments which don't have proper controls to prevent them from drawing the wrong conclusions, nor should they be deriving conclusions based on an statistically insignificant sample.

      Arguably, the ability to design and implement properly controlled experiments and derive statistically significant results is what makes an experimental scientist and experimental scientist.

    2. Re:Falsifiability. by aussersterne · · Score: 2, Insightful

      It's always very interesting to see reactionaries/creationists/evangelicals/luddites who don't understand the scientific method attempt to judge it using the framework of their own belief system, namely making the assumption that scientists must be like gods and their research therefore edicts that claim to come from on high, and thus, when those "edicts" don't hold true, it stands to reason that they are false gods, rather than The One True God that such people seek.

      I'm not sure that there's a way to ever really reframe the worldview of people socialized in such a way to help them understand the secular, methodical, aggregate-dialectic nature of of the scientific method.

      You'd think that the results it produces (i.e. the very computers, electricity, television, and telephone used by so many reactionaries to try to preach the ills of the scientific method) would go some distance toward demonstrating to them the empirical utility of the method for instrumental-rational gains (regardless of the merits of such), but no--they remain oblivious to the obvious paradox.

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    3. Re:Falsifiability. by aussersterne · · Score: 2, Insightful

      The results. It's all about the results. If it produces things that work, and that meet goals (the validity of those goals being another matter) then its functionality is unassailable.

      To claim that science is false or that scientists are the same as priests is to completely ignore a history of socially powerful, yet materially impotent priests and a contrasting history of socially impotent, yet materially powerful scientists.

      I'm playing with you a little bit now, but you get the point. :-)

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      STOP . AMERICA . NOW
    4. Re:Falsifiability. by Spy+Hunter · · Score: 5, Insightful
      Not exactly. Science is supposed to be a series of experiments designed to prove or disprove hypotheses. Having hypotheses disproved is of course a normal part of this process. However, having different experiments prove and disprove the same hypothesis is *not* a normal part of a healthy scientific process. It indicates either an incorrectly formed hypothesis or errors in experimental methods.

      Obviously errors are not completely avoidable because people are fallible; that's why we try to reproduce results and practice peer review. But I should think we ought to do better than having 33% of our supposedly "proven" hypotheses eventually disproved by subsequent experiments.

      Note that I'm not talking here about trivial things like Netwon's laws of motion being "disproved" by relativity. Relativity is more like a generalization of Newton's laws than a refutation, and that *is* a part of the normal scientific process. I'm talking here about medical studies which come up with conflicting results or the innumerable global warming studies that the scientific community can't make up its mind on (for example).

      --
      main(c,r){for(r=32;r;) printf(++c>31?c=!r--,"\n":c<r?" ":~c&r?" `":" #");}
    5. Re:Falsifiability. by radtea · · Score: 2, Insightful

      However, having different experiments prove and disprove the same hypothesis is *not* a normal part of a healthy scientific process. It indicates either an incorrectly formed hypothesis or errors in experimental methods.

      Nonsense. Science is carried out by human beings, and human beings make mistakes. Healthy processes accomodate that fact.

      Publishing the results of those mistakes, honestly and fully for the critique of others, is part of the scientific process. Having those mistakes corrected by later researchers who have the benefit of seeing what earlier researchers have done and the luxury of contemplating the problem from the perspective of "How do I improve on this?" rather than the vastly more difficult, "How do I do this the first time?" is also a healthy part of the scientific process.

      The day no one ever publishes anything for fear it might not be the perfect, irrefutable experiment is the day that science is dead.

      --
      Blasphemy is a human right. Blasphemophobia kills.
    6. Re:Falsifiability. by iq+in+binary · · Score: 2, Insightful

      More than half of these fallacies can be attributed to the medical field.

      Most importantly, the subscription-drug companies.

      I dare you to look it up and prove different. Thus is the basis of science, as mentioned earlier.

      Money motivates science just as much as any other. Look at asbestos, used to be it was approved by the FDA. Decades following, was proved harmful by too many studies to ignore.

      Just a suggestion, give ANY "scientific fact" at least a decade before you believe it to hold any water ;)

      --
      Of all the Universal Constants, here's one I know: Nice guys finish last ;)
  6. Better science education required. by Colin+Smith · · Score: 4, Insightful

    The fact that they get away with it is a shame. It's even worse when they have an influence on government policy. Ugh.

    Lots of people can't think of a good reason to do science, maths and statistics at school. Well, a bloody good reason is so you can prevent the wool being pulled over your eyes.

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    Deleted
  7. Re:more like by Daniel+Dvorkin · · Score: 4, Insightful

    Aaargh. Comments like this turn up in droves in every story that mentions statistics (in any light, whether good or bad) and ... wait for it ... they're always wrong. 100% of the time. I can state that with absolute certainty. No margin of error.

    The fact is, yes, statistics can be misused. So can every other field of study. But used right, statistics are a tremendously powerful way to understand our world, and often reveal information that can't be obtained any other way. And believe me, nobody gets more peeved at statistics abuse than statisticians do.

    But that's okay, pal. Just keep on making fun of things you don't understand. The smart people of the world will keep on working, keep doing things that make your and everyone else's life better, whether you know it or not.

    --
    The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
  8. No shit by grasshoppa · · Score: 2, Insightful

    When companies can buy reports and studies to say whatever the fuck they want them to say (*cough*microsoft*cough*), of course they are going to be bullshit.

    Who's surprised by this? Seriously.

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  9. Science by press conference by jokestress · · Score: 5, Insightful
    Sadly, this has become a cottage industry for less scrupulous publicity-hungry hacks in academia and elsewhere. Think Clonaid or cold fusion. Come up with some hasty conclusion and make a grand announcement before the data is available or has been tested by others.

    Even worse are the lazy journalists who report it. After a New York Times piece last week claimed bisexual males were "lying" based on results from a highly questionable study, I reminded their editors of this excellent piece Blinded by Science in Columbia Journalism Review.

    This kind of sloppy reporting is perfect for lazy journalists-- it's a three-for-one deal. They get to break the news, and then later they have a second story when real experts point out the flaws, and a third when the people finally get discredited. More evidence of the shameful state of journalism in this country.

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  10. Re:The Statistical Methods in Most Studies are Fla by Skippy_kangaroo · · Score: 2, Insightful

    No - the standard way to report statistics is with a 95% confidence interval (i.e. there is a 95% chance that the true value lies within the interval quoted). It's just a norm that has nothing to do with overblown results (at least not directly) and nothing to do with the study.

  11. Re:Obviously flawed by smittyoneeach · · Score: 1, Insightful

    No, really: internet traffic really is doubling every six months!
    It is!
    No, please don't call my bluff!
    What are those cuffs about?
    Screw you all! SCREW YOU ALL!

    --
    Get thee glass eyes, and, like a scurvy politician, seem to see things thou dost not.--King Lear
  12. Re:Obviously flawed by queef_latina · · Score: 1, Insightful
    Unfortunately, this is now a cottage industry for unscrupulous publicity-hungry hacks in academia and elsewhere. Think Clonaid or cold fusion. Come up with some hasty conclusion and make a grand announcement before any data is available or has been tested by others.


    Even worse are the lazy journalists who report it. After a New York Times piece last week claimed bisexual males were "lying" [nytimes.com] based on results from a highly questionable study, I reminded their editors of this excellent piece Blinded by Science [cjr.org] in Columbia Journalism Review.

    This kind of sloppy reporting is perfect for lazy journalists-- it's a three-for-one deal. They get to break the news, and then later they have a second story when real experts point out the flaws, and a third when the people finally get discredited. More evidence of the shameful state of journalism in this country.

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  13. winner-take-all vs. long-tail effects by G4from128k · · Score: 4, Insightful

    Connectivity - global media, the internet -- have created a winner-take-all world that drives both the creators of studies and the reporters of studies toward hyperbole. If someone wants their 15 minutes of fame, they need to do (or appear to do) something spectacular. When attention is a scarce resource (because of an explosion of applications/demands for attention), then it drives people toward excessive behavior in crafting and reporting the results of studies.

    At the same time, I wonder if the long tail efect means that an increasing number of once-obscure, high-quality studies are being discovered, read, and used by an increasing number of people. Those that do create unbiased studies may not get much popular press, but they do become more widely read due to Google.

    Ultimately, we seem to be floating in a rising tide of both good and bad studies. Perhaps the ratio of studies is being biased toward the bad (winner take all) but the ratio of impressions -- the numbers of times that good studies have been accessed -- has actually improved due to long-tail effects.

    --
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  14. Re:Obviously flawed by Anonymous Coward · · Score: 1, Insightful

    The title to this "Study Shows One Third of All Studies Are Nonsense" is just wrong. If the author read the article it would be obvious the problem. Hell the first line is this:

    "Controversy and uncertainty ensue when the results of clinical research on the effectiveness of interventions are subsequently contradicted."

    Effectiveness of interventions! This only looked at studies in which interventions were involved. NOT ALL STUDIES.

    To hyperbolize in the same manner..... I think the author is the dumbest person in the entire universe.

  15. Post is misleading by Ingolfke · · Score: 2, Insightful

    The research was done for MEDICAL studies, not tech studies, or animal habitat studies, or psychological studies, or sociological studies... only medical studies. Nowhere in the title or the post's main body is this mentioned. This is very poor reporting of the news. It is misleading. The study also only measured studies from 1990 to 2003. That's 13 years not 15 years!

    Word to the wise, don't trust the press at face value. Expect sources, preferably cited and available for you to review, and check your facts before you buy into whatever the press happens to be reporting today.

  16. Re:Obviously flawed by InvalidError · · Score: 2, Insightful

    Being able to make up stats and get away with it is one of the nice things about having a PhD... most people do not have the qualifications nor the data necessary to expose the made-up nature.

    This appears to be particularly frequent in more abstract (non-maths) sciences like environment. (I once had lectures on the topic where the speaker cited stats that did not match the notes and were inconsistent across presentations.)

  17. Re:/. posting shows 99% of /. postings are bullshi by cshark · · Score: 2, Insightful

    So if a third of all studies are overblown, how do we know that this study isn't overblown or inaccurate? Hmmm?

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  18. the main reason by zogger · · Score: 2, Insightful

    The main reason that journalism is "flawed" is because in the MSM or Main Stream News, either print or broadcast, the main focus is on making money. It's a "business" first. You will have to somehow make it be "news" first to get more accuracy and objectivity in reporting.

    And then it could segue into something roughly analagous to the debates over for-sale closed source software and collaborative information-sharing free software. Could a news reading public be persuaded to actually become critical reporters and "share" news freely? Could it replace the expensive and established profit motive design of "news" as we know it today?

    Some might say blogging is at least an attempt in that direction.

  19. Wait a minute... by Phredd · · Score: 2, Insightful

    Just how do we know this study isnt one of the 1/3?

    --
    Phredd - "I have found people tend to take you far less seriously once you start waving your genitals at them..."
  20. Re:more like by nine-times · · Score: 4, Insightful
    Statistics (and numbers in general) are an incredibly useful tool. They do help us digest massive amounts of information into forms that we can use.

    However, statistics are not determinative. This is a mistake I've heard from both laymen and experts. The fact that, according to what's known (and factored in to the calculation) an event is 99.999999999% likely to happen... well, that doesn't mean it will happen. Really, it doesn't matter how unlikely your statistics demonstrate something to be, it won't prevent the unlikely from happening.

    In fact, it's demonstrable from statistical analysis that we should expect tremendously improbable events to happen quite often, and that the chances of the most probable outcomes to occur at every instance is an incredibly unlikely outcome as time stretches on.

    So statistics are an interpretive tool, not an answer. Statistics alone cannot tell you what will happen, they can't tell you what has happened, and they certainly cannot tell you what should happen. And all these comments you're talking about, I think they come from a valid frustration borne from sloppy reporting telling us "scientists have discovered that 75% of" this and "they now know that 25% of" that outside of any meaningful context.

    And what's the likelihood that all these percentages are correct? What's the margin of error, and what's the margin of error's margin of error? Certainly the people telling us these "facts" (reporters) have no idea.

  21. Re:nice by Durzel · · Score: 2, Insightful

    Presumably the expert was alluding to the fact that an incident such as this, so soon after WTC, could take on a greater significance than had it been looked at in isolation.

    It could lead to an escalation in hysteria, racial hatred and so forth from otherwise-rational people who believe the end of the World is nigh, or something.

    Case in point: Following the London attacks there was a bomb scare in Birmingham (about 120 miles North) which resulted in 20,000+ people being evacuated from the city centre. It turned out to be a firework. Taken in isolation I'm sure the response to something like this would be a lot more measured, but coming so soon after the events in London everyone (including the Police) reacted in a typical knee-jerk fashion.

    I guess my point is that there is obviously never "a good time" for a plane to crash into a neighbourhood, but there is certainly a less dramatic time for it to happen.

  22. Please define religious nut by anomaly · · Score: 2, Insightful

    I'm curious to know how Mr. Gribbin defines a religious nut.

    While there are a large number of people who reject facts and reason due to their a priori commitment to a religious beliefs, there are a great number who do the same whose religion is science itself.

    That is to say, preconceived notions and personal bias prevent many so-called scientists from acknowledging facts and realizing that their pet theories are baseless.

    As an example, I offer Carl Sagan. Here was a man who made a nice living talking about extraterrestrial life. Is there ANY evidence of extraterrestrial life? Is there ANY science that supports it? After all, the best that the SETI institute has is Drake's equation which at best merely multiplies speculation upon speculation.

    Is SETI science? Perhaps, but Sagan's beliefs and public discussions were based on fantasy and hope rather than fact.

    My point is this: Bias appears in religion and in the name of science. Science has dirty hands, too.

    Remember, power tends to corrupt, regardless of world view. I'd be willing to bet that a similar book could be written demonstrating horrible abuses of human rights where science was allowed to 'progress' unchecked by morality.

    Finally, it is important to note that much of science has been advanced by people with strong religious convictions. Pascal, Pasteur, Lister, Knuth, Kelvin, Joule, Carver, Bacon, Boyle, and many many others. Strong religious conviction is NOT the antithesis of scientific advancement, as demonstrated by the legacy of those I listed above and I could list many more.

    Respectfully,
    Anomaly

    --
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