The Mathematics of a Trip to Mars?

hakonhaugnes wonders: "Since trips to Mars seems commonplace (NASA has sent one every 26 months), I thought it made sense to try to understand how the interplanetary trajectory is calculated. NASA's page is deploringly void of intricate details. I found this excellent page, but it still left me feeling that I was missing something. Surely the calculus must go beyond two bodies (mars/earth)? (It seems there are commercial MATLAB scripts available but at $150 it went beyond the defensible to satisfy my curiosity). Are there any curious Slashdot readers with the usual great insight into how to calculate a trip to Mars?"