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Missing Lab Mice Infected With Plague

Buford C Nuzzle-Chunks writes "PhysOrg is reporting that 'The FBI and New Jersey officials have started a hushed but intensive search for three missing lab mice reportedly infected with deadly strains of plague'. The Washington Post says it's not that big a deal, but I was dismayed at the PhysOrg article's quote from Richard Ebright, a Rutgers University microbiologist, about certain federal bio-terrorism labs: 'You have more security at a McDonald's than at some of these facilities.'"

13 of 320 comments (clear)

  1. Have they checked the obvious? by codergeek42 · · Score: 5, Insightful

    If they're "infected wqith a deadly plague," perhaps they simply died?

    1. Re:Have they checked the obvious? by The+Angry+Mick · · Score: 4, Insightful

      One of the articles I read said that a scientist was speculating just that. They got out and probably died not too far from the lab.

      What I'm curious to know is, if they died and were subsequently consumed by either a larger animal (dog, cat, etc.) or smaller insects, would the plague be transferable to the consumer? In other words, could a roach eat the remains of the mouse, a rat eat the roach, and the whole plague start over yet again?

      --

      I'm not tense. I'm just terribly, terribly, alert.

    2. Re:Have they checked the obvious? by BrokenHalo · · Score: 2, Insightful
      ...if they died and were subsequently consumed by either a larger animal (dog, cat, etc.) or smaller insects, would the plague be transferable to the consumer?

      Since bubonic plague is a bacterial condition (from Yersinia pestis) the simplest answer is: Yes.

      The point is, though, that the bacterium has to enter the bloodstream by one means or another, and a pandemic is unlikely since the condition (at least in its original form) is treatable by common antibiotics.

      A more insightful question here might be "what the hell are these guys doing playing around with nasty pathogens like this?".

      I demand and expect an immediate and comprehensive investigation by the UN WMD inspection teams.

      In my dreams (sigh) :-(

    3. Re:Have they checked the obvious? by StillNeedMoreCoffee · · Score: 2, Insightful

      But on the other hand we may have shot ourselves in the foot with our modern technologies as well as having AIDS so prevalent (esp in Africa) so there are large populations of compromised immune systems. We also have transplant patients and other people on steroids walking around with compromised immune systems. If the plauge (or avian flu) gets out we have some fertile fields for them to grow in that were not present in previous centuries. So things will not be simplier and if antibotic resistant strains appear we are in deep shit. We have seen that already with some of the strep and staf strains getting harder and harder to cure (my father spent 2yrs fightning Mersa (hour whatever the acronym is) and have to be vigilent continuously to prevent an outbreak.

      Don't think modern technology is just a solution and not part of the problem.

  2. Just great by chris09876 · · Score: 3, Insightful

    It's always nice to see that the people who deal with dangerous biohazard materials are so careful with what they do. I guess you just get complacent after awhile... it happens with everything. It's unfortunate that there aren't better routines and checks in place to be absolutely certain this kind of thing doesn't happen.

    Even if it's no big deal this time, who's to say what could happen in the future if mutant infected lab animals are allowed to roam free? ;-)

  3. Should be no problem now by Analogy+Man · · Score: 1, Insightful
    It should be evident by recent performance of the Department of Homeland Security and FEMA all of the billions spent to be ensure biological WMD stay under wraps.

    As GW would say..."They're doing a great job!"

    --
    When the people fear their government, there is tyranny; when the government fears the people, there is liberty.
  4. The really scarey part.... by evenprime · · Score: 4, Insightful
    The really scarey part is that they had to interview the staff and give them lie detector tests to see if anyone had liberate^H^H^H^H^Hstolen the mice....

    I don't get those PETA/ALF types....

    --

    "Weapons should be hardy rather than decorative" - Miyamoto Musashi
    I think that goes for OS's too
  5. Re:Hushed? by StillNeedMoreCoffee · · Score: 2, Insightful

    On the contrary, plauge spreads from the fleas on rats biting other rats and humans and other animals. I think we have a lot to worry about. Especially with other catastorphies on the horizon like the avian flu. Link that with a lot of AIDS compromised immune systems and all those other people on steroids and other medication that compromises the immune system and we have a unique situatation that has not existed before when pandemics were present.

    Be afraid, be very afraid.

  6. Re:The British are going to help you... by Anonymous Coward · · Score: 2, Insightful

    Umm... Get your stereoypes straight.

    The retarded monkey became president.
    The rage infected monkey became the leader of the Democratic Party.

  7. This really isn't a huge deal by radiashun · · Score: 2, Insightful

    Given that plague isn't a rare phenomenon (especially out West), I don't see too much to be concerned about with regards to infected mice running around. Some streptomycin or gentamycin should fix the problem. The article made this sound like it was wild-type Y. pestis, but if it were a hypervirulent type (which they wouldn't indicate), then I would be very concerned. The Soviet Union developed antibiotic-resistant strains of Y. pestis and the Japanese actually used it as a weapon against the Chinese (by dropping infected fleas from airplanes).
    Given the tidbits of information that have been published on N. Korea's BW program, I'm sure there are places in the US that study hypervirulent BW agents.

    I'm just amazed by the lack of security at this place, which should be BSLIII (the second highest level of containment).

  8. Re:Hushed? by tabrnaker · · Score: 2, Insightful

    Or be very happy that this will teach the evils of modern antibiotics. Sure people will die. But people will LIVE better afterwards.

  9. Exactly. by Anonymous Coward · · Score: 3, Insightful

    This is a complete NON-Story that has its roots in the Patriot Act.

    First. As glarvat mentioned, the plaque is everywhere. In NM, my home state, rabbits, prarie dogs, gophers, you name it carry the plaque. So if Osama wants to get ahold of some Yersinia pestis he need look no further than the bushes outside his mud-brick hut in Northwestern Pakistan.

    Second. The real reason this is an issue is because of the professor from Texas who had apparently misplaced some samples of the Ames strain of Anthrax, which is commonplace in many labs across the country. Now he's in prison. There are details of the case all over the web, but just like everyone else in every profession, as scientists, we make mistakes, don't take perfect notes, misplace things, lose things, etc.

    Given that these mice--and a vial of Ames Anthrax--are not a threat and are widely available using simple techniques all over the globe, the normal response would be to note the discrepancy, tell the boss and continue with your work. Work that--you know--is designed to combat these same bugs and actually do something good for Society.

    So in the past, this has surely happend at many labs and there were no problems and there really isn't an threat to the public. Now, the FBI swoops in, asks questions, then tries to catch the professor making a misstatement. Even though the original offense, not taking good enough notes about what happened to the mice, is not a crime, the professor will find himself fired, or in jail, or both.

    Mice don't have RFID tags and the need to be moved into new cages 2 or 3 times a week. Although not common, they do get misplaced during cage transfers and or experimental procedures. Unfortunately, this professor will likely lose his job because of a simple mistake.

    Welcome to 1984.

  10. Re:Hushed? by StillNeedMoreCoffee · · Score: 2, Insightful

    If you saw the movie with Robin Williams about a doctor that found a treatment for severly autistic patients that brought them back to full life for awhile until the treatment lost its effect and the went back to an unresponsive state. The same can be seen happening with modern antibiotics. The things it used to treat have evolved past and around those treatments so there are more and more desease resistant strains that we have no cure for. In another hundred years we may end up where we started with just as many pathogens killing us as was the case before antibiotics were invented.

    Its our grandchildren that may suffer and die because of our irresponsible use of modern medicine. I know my father had to have 6 operations including 3 leg bypass operations and an artificial knee removed and replaced because a strain of bacteria has become antibiotic resistant because we have miss used that technology. He lost 2 years of his life being essentially bed ridden. So I see both sides, the benefit and the cost. If you don't realize there is a cost for unrestrained behaviour, or if you think that modern medicine cures problems for good you had better do some more research.

    My point was that modern medicine with transplant patients and other patients on cortical steroids and related drugs have comprimised immune systems which means if a nasty pandemic occures they are at extremely high risk. The avian flue is an example. Just last night in Nightline they talks about the fact that there is "NO" vacine for it as yet and if it mutates to a human to human transmission we could be looking at an epidemic that would rival the 1918 outbreak of Spanish Flu which if I remember right killed about 200,000 in this country alone. The vacine would take about 6mo to create after the pandemic started and they said that no living human has ever encountered this before so there is not natural immunities build up anywhere. They say about a 50% mortality rate from what they have seen.

    In the article they talk about a nasty version of Plague, well if is gets out I think no one living has build up immunity for that either, so we could be in for an interesting year.