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Nobel Prize in Chemistry Awarded

An anonymous reader writes "The Nobel Prize in Chemistry for 2005 has been jointly awarded to Robert H. Grubbs (California Institute of Technology), Richard R. Schrock (Massachusetts Institute of Technology), and Yves Chauvin (Institut Français du Pétrole) for the development of the metathesis method in organic synthesis." Advanced [PDF] and supplementary [PDF] information is also available from the Nobel Prize site.

114 comments

  1. Fuel? by Shadow+Wrought · · Score: 1
    From TFA: This year's Nobel Prize Laureates in chemistry have made metathesis into one of organic chemistry's most important reactions. Fantastic opportunities have been created for producing many new molecules - pharmaceuticals, for example. Imagination will soon be the only limit to what molecules can be built!

    So does that mean that we can build long chain carbon molecules like, say, gasoline, out of other organic material like, say, chicken shit? 'Cause that's what I'm imagining.

    --
    If brevity is the soul of wit, then how does one explain Twitter?
    1. Re:Fuel? by thc69 · · Score: 4, Informative

      Well, we can already make diesel out of nearly any kind of oil extracted from nearly any biological material...

      --
      Procrastination -- because good things come to those who wait.
    2. Re:Fuel? by metternich · · Score: 3, Informative

      Synthetic Oil has been around for a long time. The Germans made oil from coal in WWII as did the South Africans under the Aparthaid Sanctions. (The Chinese are now starting to use this techlonogy as well.) I don't if this new method will help with this, but if it could be done at a large scale I imagine it would.

      --
      Facts do not cease to exist because they are ignored.
    3. Re:Fuel? by thebdj · · Score: 2, Informative

      this new method

      Remember this is the nobel prize we are talking about. These are not necessarily new methods, which is something people have repeatedly forgotten over the last few days of science award posts. Many of these discoveries have been done over time, and in fact started work in the '70s or earlier and may have been finalized in the late 80s or early 90s. Nobel Prizes do not have to be given to you the year you create some new and wonderful thing, and most often this is not the case. Think of the Nobel Prize more as a lifetime achievement award (I mean most the recipients are typically of advanced age) in your scientific field.

      --
      "Some days you just can't get rid of a bomb."
    4. Re:Fuel? by suchire · · Score: 4, Informative

      Not only is this a new method, but it isn't really all that practical for the synthesis of fuels. You can't run this reaction with just substrates and the Grubb's catalyst; you have to have solvents, which cost money. The catalysts have a finite lifetime and turnover, so you also have to replace those. That's not really very cost effective, in the end, compared to simply adapting technologies to use the substrates as fuel directly.

      --
      Such irE
    5. Re:Fuel? by LukeWink · · Score: 1

      So does that mean that we can build long chain carbon molecules like, say, gasoline, out of other organic material like, say, chicken shit? 'Cause that's what I'm imagining.
      Maybe, but I'm willing to bet that the energy consumed in making such a molecule will be more than the energy derived from burning said molecule. Kind of defeats the whole purpose of synthesizing gasoline.

    6. Re:Fuel? by jimbolauski · · Score: 1, Insightful

      I doubt even gasoline would live up to those standards the energy to pump it out of the ground transport it to a refinary, transport to the gas station and pump it into your car. The more pertitant question would be can it be done cheaply enough to cost less than gas and the awnser is no. Synthic oil costs more than regular because it costs more to produce.

      --
      Knowledge = Power
      P= W/t
      t=Money
      Money = Work/Knowledge so the less you know the more you make
    7. Re:Fuel? by Fred_A · · Score: 1
      [ ... ] extracted from nearly any biological material...

      Oh no ! "Fuel Green" is people !
      --

      May contain traces of nut.
      Made from the freshest electrons.
    8. Re:Fuel? by twiddlingbits · · Score: 3, Interesting

      That's the Fischer-Tropsch process to take coal and convert/refine into high octane gasoline. It was invented in Germany in the 1920's. Fischer was awarded the Nobel in Chemistry (1902) but not for for this idea. South Afica makes most of thier gasoline this way still since they adopted the process when embargoed in the 1980s for Apartheid. SA has lots of coal but not much oil. Sasol and Shell are using the process today to make gasoline from coal in SA and from natural gas in Malaysia. It's quite a good process, very scalable to industrial use. Why we don't use it in the USA I don't know as we also have plenty of coal.

    9. Re:Fuel? by Anonymous Coward · · Score: 0

      Actually if the reactant and product are liquid no solvent is required. The fatty acid esters used in making hydrocarbons are liquids as are the product olefins unless they exceed ~16 carbons, but in that case they are low melting and you can run the reaction warmer. I actually worked for Grubbs commercializing this technology and I believe the real power of this technology is in synthesis of active ingredients for pharma applications.

    10. Re:Fuel? by absolutlactam · · Score: 0

      Of course you can use Grubb's catalyst without solvents! Hell, if you've seen his talks where he makes bulletproof plastics, you'd know that with a catalyst loading of a million to one, using the carbene ligand, you can make this stuff in a bucket with no solvent and pour it in a mold.

  2. Grubbs is great by rgmoore · · Score: 5, Interesting

    I took a class (Ch41, Chemistry of Covalent Compounds) from Professor Grubbs, and he is an excellent teacher as well as a great scientist. He can also take a joke. The following was published in Nothing, an unofficial humor paper published by a couple of bored Techers, and based by a standard lecture that Grubbs gave to every Organic Chemistry class before their first test.

    Caltech Professor Lashes Out Against High Energy Reaction

    In a remarkable demonstration of unbridled passion, Caltech professor Rober Brubbs yesterday lashed out against a high energy reaction--namely, one which includes the formation of a quintuply-bonded carbon. Provoked to a fever pitch by the prospect of dsp3 hybridization in a first period species, he opined: "This reaction doesn't have a chance in hell of happening." He proceeded to characterize quintuply-bonded carbons as "bad", "no good", "undesirable", and "a damned silly notion." After his oration Professor Gurbbs nonchalantly continued with the lecture.

    Earlier this mornin, students and other various members of the Caltech and Pasadena communities picketed Grubbs' office to demand retraction of his libelous comments. At the protest, Jennifer O'Leary, spokeswoman for the Quintuply-Bonded Carbon Anti-Defamation League, characterized Grubbs's statement as "shocking" and vowed, "He hasn't heard the last of us. High-energy reaction have just as much a chance of happening as any other. Grubbs's evil exergonocentrist demagoguery demands retraction." Nothing has also received reports from reliable sources that Grubbs has received death threats from both the Brotherhood for Hybridization Freedom and the Carbonic Liberation Front, left-wing propentavalent reactionist groups.

    In a response to the same event, the Coalition for Traditional Carbon Valence made public this statement: "We applaud Professor Grubbs for his courageous stand against the poison of quintuple bonds."

    Professor Grubbs was unavailable for comment after the lecture as his office refused to return phone calls.

    Caltech Security stated that in order to maintain a suitable atmosphere for study and research it would investigate the matter to the fullest extent of its capabilities.

    (Information in this story gathered by reporters on fat expense account.)

    --

    There's no point in questioning authority if you aren't going to listen to the answers.

    1. Re:Grubbs is great by Mr.+Underbridge · · Score: 2, Funny

      Pisses me off, I just left 7 months ago...I imagine I'm missing some great Chem department parties.

    2. Re:Grubbs is great by LordKronos · · Score: 1

      It's been a LOOOONG time since I took my chemistry class, so I can't seem to figure out exactly what you are talking about. What is quintuply-bonded carbon? Is this one of those jokes like dihydrogen monoxide?

    3. Re:Grubbs is great by rgmoore · · Score: 4, Informative
      What is quintuply-bonded carbon? Is this one of those jokes like dihydrogen monoxide?

      Nope. Carbon can only form 4 bonds at a time. During the course of a reaction, there may be short-lived meta-stable carbon species with only 3 bonds, or reactive intermediates (i.e. unstable things that are a transition state between two more stable forms) that have 3 bonds plus one bond that's half made and one bond that's half broken, but there aren't any forms with a full 5 bonds. Undergraduates taking their first Organic test, though, are apt to draw such quintuply bonded carbons and thus get answers wrong on their tests.

      Prof. Grubbs always warns his students not to make that mistake before their first test, and even goes into a mini-rant on the topic much like the one in the article. I wouldn't be surprised if the "This reaction doesn't have a chance in hell of happening" were a direct quote. The rant is very memorable, and I'm sure that everyone who took Organic from him would remember it. Despite this, many students will go on to make exactly the mistake that he warned them against, which I assume is the reason that he's so vehement about it.

      --

      There's no point in questioning authority if you aren't going to listen to the answers.

    4. Re:Grubbs is great by Anonymous Coward · · Score: 1, Funny

      I second that. I am the original submitter and also an undergrad at Caltech.

      Funniest thing in that Ch 41a class was when he was demonstrating some reactions. He mixed H2 and O2 together and threw a catalyst and a spark in there. It was the loudest sound ever to resonate the lecture hall. Then he got another bottle and threw still more. He did it yet a third time, and this time, I wised up and ran from my front row seat to the back of the auditorium.

      Great guy.

    5. Re:Grubbs is great by rdwald · · Score: 1

      WTF are you talking about? Ch 41 is Organic Chemistry (though if you mean one term of it, I guess it could have a more specific name), and there's no such publication as the Nothing. There's the BFD and the Fishing Quarterly, but that's about it for humorous publications. (Unless you want to include the Tech's comically bad production values...but I digress.) Anyway, what year did you graduate?

    6. Re:Grubbs is great by suchire · · Score: 1

      It's been found that carbon can, however, be pseudo-hypervalent via a three-center two-electron bond. It's nearly equivalent to having hypervalent carbon, since the molecule becomes symmetric. Carbonium-carbenium chemistry is really interesting...

      --
      Such irE
    7. Re:Grubbs is great by rgmoore · · Score: 1

      At the time I was taking the class (1990) the formal title of Ch41 was "Chemistry of Covalent Compounds", though everyone called it Organic Chemistry informally. Nothing was a completely unofficial publication put together by Zach Berger and DA Kornreich. They just wrote stuff, photocopied it, and left the copies out where people could find them. Nothing seems to have died when their courseload started to increase; I don't remember it coming out at all by my senior year.

      --

      There's no point in questioning authority if you aren't going to listen to the answers.

    8. Re:Grubbs is great by rdwald · · Score: 1

      I guess that makes sense. I'm a current junior, and recall taking Ch 41a with Grubbs last year. Sorry for being confrontational.

    9. Re:Grubbs is great by rgmoore · · Score: 1

      Does Grubbs still do his "no pentavalent carbon" talk before the midterm?

      --

      There's no point in questioning authority if you aren't going to listen to the answers.

    10. Re:Grubbs is great by rdwald · · Score: 1

      Not that I remember, but it's hard staying conscious during a 9 AM class.

  3. Embarassed of a Nobel prize? by n01 · · Score: 5, Interesting
    1. Re:Embarassed of a Nobel prize? by gowen · · Score: 2, Funny

      He'll still mention it when chatting up women, though. That's the French for you.

      --
      Athletic Scholarships to universities make as much sense as academic scholarships to sports teams.
    2. Re:Embarassed of a Nobel prize? by DeeSnider · · Score: 3, Insightful

      That article was kind of sad to me. The guy seemed still in grief from his wife's death, and annoyed that 30 years after the fact tons of reporters started knocking on his door practically unannounced. Can't say I blame him. I wouldn't want that kind of sudden publicity now, much less at 74 for something I did half my life ago.

    3. Re:Embarassed of a Nobel prize? by Fred_A · · Score: 1

      Right, like what else are you going to say when chatting up women when you're an organic chemistry geek ?

      --

      May contain traces of nut.
      Made from the freshest electrons.
    4. Re:Embarassed of a Nobel prize? by Guppy06 · · Score: 1

      You mean in France that chemistry geeks actually get to talk to women?

  4. But as Sideshow Bob says... by wernst · · Score: 5, Funny

    Yes, yes, that's very interesting and all, but what I want to know is who won the Nobel Prize this year for "Attempted Chemistry?"

    1. Re:But as Sideshow Bob says... by kbrosnan · · Score: 4, Funny

      You can find out tommorow when the IgNoble awards are released.
      http://www.improb.com/ig/2005/2005-details.html

      Last year the Chem Award went to Coca-Cola Co. of Great Britain for turning H20 into a cancer causing material.
      http://www.guardian.co.uk/business/story/0,3604,11 74127,00.html

      --
      These people look deep within my soul and assign me a number based upon the order I joined. -Homer Simpson
    2. Re:But as Sideshow Bob says... by Anonymous Coward · · Score: 0

      They get those all year.
      http://www.darwinawards.com/

    3. Re:But as Sideshow Bob says... by Fred_A · · Score: 1

      Well, we all know how nasty DHMO can be at times...

      --

      May contain traces of nut.
      Made from the freshest electrons.
  5. Metathesis is like swinging by Dystopian+Rebel · · Score: 2, Funny

    "Metathesis can be compared to a dance in which the couples change partners."

    Whoo hoo! Grubbs, Shrock and Chauvin have done a great service to married SlashDotters.

    --
    Rich And Stupid is not so bad as Working For Rich And Stupid.
    1. Re:Metathesis is like swinging by Viper+Daimao · · Score: 2, Funny

      married SlashDotters.

      Who?

      --
      "In the game of life, someone always has to lose. To me, if life were fair, that someone would always be Oklahoma." -DKR
  6. Re:dupe by nothingx · · Score: 1

    I think you're thinking of the physics award. This one's for chemistry, a related but separate field of science. I'm also sorry to hear that you find Nobel prize winner's stories "dull", I can not imagine what other greatness you must aspire too.

  7. Re:guess what !! by Anonymous Coward · · Score: 0

    Uhhhh....Congratulations???

  8. quote by illuminix · · Score: 1


    Prizes are for children.

    -- Charles Ives, upon being given, but refusing, the
                                          Pulitzer prize

    --
    http://cubemonkey.net/quotes -- fortune-mod quote generator
    1. Re:quote by Mr2cents · · Score: 1

      No, they are for self-promotion. He seems to have understood that quite well, since you're still quoting him. ;)

      --
      "It's too bad that stupidity isn't painful." - Anton LaVey
  9. My, aren't you clever now by Anonymous Coward · · Score: 0

    I'd just like to be the first to congratulate you on being a complete dumbass!!

  10. No Theory, no equations?-I am disappointed! by Anonymous Coward · · Score: 5, Funny

    They used to have the good habit of giving Nobel Prizes in Chemistry for physical chemistry, clean spectroscopical experiments, nice theories with lots of equations, sophisticated mathematics, quantum theories etc. Many physicists, not olny chemists, magaged to receive the Nobel Prize in Chemistry. Not anymore, now smelly, organic chemistry and biochemistry grab everything! Think urine and meat and blood and saliva analyses and other gross things! I am VERY disappointed!

    1. Re:No Theory, no equations?-I am disappointed! by Anonymous Coward · · Score: 0

      On the contrary, three prizes in the last 10 years involve plenty of P-chem.

      2002: Wuthrich (NMR), Tanaka and Fenn (mass spectrometry)
      1999: Zewail (femtosecond spectrscopy)
      1998: Kohn and Pople (quantum mechanics and DFT, all theory)

  11. Well deserved by JustNiz · · Score: 1, Funny

    >> This represents a great step forward for "green chemistry",

    Wow they must be smart, mine always comes out an icky brown colour.

    1. Re:Well deserved by w.timmeh · · Score: 1

      Icky brown?

      Well, was it supposed to be a white powder, white crystals or a very pale yellow goo? We are talking about organic chemistry, after all.

  12. awesome potential by smellsofbikes · · Score: 5, Interesting
    These are spectacular reactions: they allow for all sorts of neat syntheses if you can just form terminal alkenes, which isn't too hard. The systems aren't horribly abusive to most side-chains so you don't have to spend lots of time (and reduce your yield) protecting everything in sight.

    I think it's interesting how many nobel prizes have been given for work on the C=C bond: Diels-Alder, Wittig, reduction, oxidation... I think that more nobels have been given for x-ray techniques than anything else, but this must be well up there. (Of course that depends on how broadly you classify your groupings.)

    But this particular synthesis is already producing some amazing results in bioactive materials, and it should be a strong industrial technique, given its apparent robustness. Back when I was doing organic chemistry, I was trying to make a weird cyclopropene using a synthesis that was multi-step and very low yield. I wish I'd read about this.

    --
    Nostalgia's not what it used to be.
    1. Re:awesome potential by drooling-dog · · Score: 1

      I would personally like to shake your hand, if only I could. I had to scroll down almost to the bottom to do it, but at least I managed to find one non-idiotic post on this topic. Ironic, isn't it, that so many Nobel winners are Americans?

    2. Re:awesome potential by smellsofbikes · · Score: 1

      Americans produce more stuff than anyone else. That means pollution, noise, and trash, as well as brilliant chemistry. Unfortunately, in the last twenty or so years, we seem to be doing a lot better on the pollution, noise, and idiotic comments side than the superb inventions side...

      --
      Nostalgia's not what it used to be.
    3. Re:awesome potential by k98sven · · Score: 3, Informative

      Ironic, isn't it, that so many Nobel winners are Americans?

      Surely you're joking?

      The USA has about 200 (give or take) laureates (counted as ones at US universities). And a population of 295 million. 0.67 per million.

      Switzerland: 28 and 7.5 million population : 3.7 per million.
      Sweden: 29 and 9 million. 3.2 per million.
      Norway: 11 and 4.5 million. 2.4 per million.
      Austria: 21 and 8 million. 2.6 per million.
      Denmark: 13 and 5.5 million. 2.3 per million.
      Germany: 89 and 82 million 1.1 per million.
      Netherlands: 16 and 16. One in a million.
      France: 49 and 60 million. 0.8 per million.
      Belgium: 8 and 10.5 million. 0.76 per million.
      Italy: 19 and 58 million. 0.3 per million.
      Japan: 12 and 127 million. 0.1 per million.

      Call it bias or whatever you want. But the US certainly isn't overrepresented.
      All figures from doing a simple laureate-search, so they're all approximate, and refer to country of residence, not birth.

    4. Re:awesome potential by Mark+of+THE+CITY · · Score: 1

      weird cyclopropene

      Doesn't that ring have a lot of strain on it? No wonder the overall reaction was low-yield. Were you using some sort of host-guest approach?

      --
      The clearance system sounds logical. It is not. It is completely arbitrary. -- John Bolton
    5. Re:awesome potential by smellsofbikes · · Score: 2, Interesting
      A lot of strain, yeah.

      I was in an advanced organic synthesis class. The project was "make something new. Preferably by an unusual synthesis." My first project is not discussable these days, given the current political climate, but my second project was making a cyclopropene, turning it into a cyclohexene (!), and then turning THAT into a spiro compound with one six and one seven membered ring. (!!!) It was way out there on the weirdness scale, but the problem was that the cyclopropene was, as one might expect, very suseptible to polymerization, so I mostly ended up making round-bottom flasks full of solid brown tar. I could dig up the papers from which I was working, but this was, uh, 15 years ago (eeeek!) and I can't remember all the details off the top of my head. I can't imagine what one could do with a metathesis reaction, although I suspect you'd spend most of your time just synthesizing the catalyst. Most of those look like boogers to make, and not very many were/are commercially available (and those that are probably cost hundreds of dollars a gram.)

      --
      Nostalgia's not what it used to be.
    6. Re:awesome potential by drooling-dog · · Score: 1
      Call it bias or whatever you want. But the US certainly isn't overrepresented.

      Until there's a Nobel Prize for Creationism and Intelligent Design, that is. We'll be filling our own children's heads with crap as we import our scientists and engineers from elsewhere.

    7. Re:awesome potential by Fred_A · · Score: 1

      You'd have to cross reference this with the funding of those universities...

      In lots of places universities are state funded, so they aren't as wealthy as the ones in the US.

      --

      May contain traces of nut.
      Made from the freshest electrons.
    8. Re:awesome potential by frozenraisin · · Score: 3, Interesting

      I'm pretty sure you can't make cyclopropenes with metathesis. The thermodynamics of that particular reaction are against you. The 1,4 diene starting material is often unreactive for transition metal catalyzed processes due to catalyst inhibition. Cyclopropenes, at least these days, are best prepared using rhodium(II) catalyzed cyclopropenation of alkynes.

    9. Re:awesome potential by smellsofbikes · · Score: 1

      I was hoping to use cyclopropenes as the starting materials and do wonderful and exotic things with them, rather than make them. I've made them already, and it sucked. Stupid rhodium catalysts.

      --
      Nostalgia's not what it used to be.
    10. Re:awesome potential by the+gnat · · Score: 1

      You'd have to cross reference this with the funding of those universities... In lots of places universities are state funded, so they aren't as wealthy as the ones in the US.

      The majority of US academic scientists, however, receive significant amounts of money (in many cases, all of their funding) from the government, regardless of whether they work at a private or public university. It's worth pointing out that the US has traditionally (over the last half-century) poured tons of money into basic research, to a greater extent than many European countries that have almost entirely public educational systems.

    11. Re:awesome potential by Fred_A · · Score: 1

      Then I suppose we have to continue to push for more public funding of research over here, despite the government saying that it should be done by the private sector...

      It's amazing that there's still some labs left in Europe really...

      --

      May contain traces of nut.
      Made from the freshest electrons.
    12. Re:awesome potential by rbgrubbs · · Score: 1

      For one-stop metathesis catalyst shopping: www.materia-inc.com

    13. Re:awesome potential by Mark+of+THE+CITY · · Score: 1

      Yeah, now. :)

      --
      The clearance system sounds logical. It is not. It is completely arbitrary. -- John Bolton
    14. Re:awesome potential by rbgrubbs · · Score: 1

      point taken -- I wasn't awake enough to notice the '15 years ago -- eeek' part.

  13. Good Show by Jim_Callahan · · Score: 2, Interesting

    I like Nobel Prizes in Chem. They're usually actually important discoveries, as evidenced by the fact that chemists use them constantly two decades after their formulation. The literature-type prizes, I'm still not so sure about.

    --
    ...it's really a sad day for America when we require a goddamn ACT OF CONGRESS to make our DVD players work properly. ~
    1. Re:Good Show by rbarreira · · Score: 1

      The literature-type prizes award people who help advance one other of human's necessities - the need to be entertained and inspired.

      --

      The AACS key is NOT 0xF606EEFD628B1CA427BEA93A9CA9773F
  14. Re:dupe by MagikSlinger · · Score: 3, Insightful
    for [frak]'s sake, do we have to read this twice? it was dull the first time round!

    <sarcasm style="dripping">
    I'm sorry today's omelette wasn't to your taste. Maybe tomorrow they'll talk about Halo and Doom 3 instead! That'd be more interesting, right?
    </sarcasm>

    --
    The bitter lessons of a veteran coder: http://bitterprogrammer.blogspot.com
  15. Who got 50% and which of them get 25% ??? by Ossifer · · Score: 1, Interesting

    According to Nobel rules, the prize be be 100% to one person, 50-50% amongst two winners, or 50-25-25% if three. I haven't been able to determine from the news stories which of them gets the 50%... Anyone know? Probably the French guy...

    1. Re:Who got 50% and which of them get 25% ??? by Anonymous Coward · · Score: 0

      They will each receive one third of the prize.

    2. Re:Who got 50% and which of them get 25% ??? by Ossifer · · Score: 1

      As I stated above, it is not possible for them each to receive 1/3.

    3. Re:Who got 50% and which of them get 25% ??? by Anonymous Coward · · Score: 2, Informative

      I don't know about the rules, but according to the nobel foundation, they will indeed receive one third of the prize.

    4. Re:Who got 50% and which of them get 25% ??? by reverseengineer · · Score: 3, Informative
      Are you sure about that? The laureates for the Chemistry prize for this year are listed here; each is noted as receiving 1/3 of the prize. I think you may be confused by the fact that a single prize can be split to honor two (and no more) different achievements in the same year.

      An example of that is here. Notice that one guy got half the prize, while two others split the remaining half. It was like half a prize was awarded for the soft-ionization MS work, which one person received, and half a prize for the NMR work, which was split between two people. No more than three persons total may split a prize though- you can't have a prize split 4x25% or 1x50%+3x16.7%. As science has become more of a team effort and an international enterprise, virtually every science Nobel given out recently has honored the maximum of three. The Nobel Foundation statute for shared prizes may be found here.

      --
      "FDA staff reviewers expressed concern about the number of patients who were left out of the study because they died."
    5. Re:Who got 50% and which of them get 25% ??? by Anonymous Coward · · Score: 0

      from the nobel prize site:

      A rule was added that in no case may the prize be divided between more than three persons (one-third to each Laureate, alternatively one-half to one of the Laureates and one-quarter to each of the other two).

    6. Re:Who got 50% and which of them get 25% ??? by digital01 · · Score: 1

      My guess is that Yves Chauvin will get the 50%. He discovered the process in the 1960's and the two American's refined it to an exact quick, painless process.

  16. A Chem Nobel Prize that actually goes to chemists! by Jonathan · · Score: 5, Interesting

    It's interesting that this year the chemistry nobel prize actually goes to chemists this year -- the last two years it went to molecular biologists...

  17. Re:A Chem Nobel Prize that actually goes to chemis by the+eric+conspiracy · · Score: 1

    Right, and in 2002 it went to two engineers and a physicist.

  18. Both of them by Anonymous Coward · · Score: 0

    no text

  19. Nobel Web Site link has cool animation by WillAffleckUW · · Score: 1

    that actually shows what they mean by the Dance of chemicals as they change partners.

    Quite nifty, provided you have a flash plug-in.

    --
    -- Tigger warning: This post may contain tiggers! --
  20. Not meant to be a lifetime achievement award by 200_success · · Score: 4, Insightful

    Actually, according to Alfred Nobel's will and the statutes of the Nobel Foundation, the prizes are meant to be awarded rather promptly:

    The interest... shall be annually distributed in the form of prizes to those who, during the preceding year, shall have conferred the greatest benefit to mankind.

    Granted, the passage of time is often necessary for the relative importance of a work to become apparent, since bold new ideas tend to be controversial and cannot be appreciated without hindsight.

    1. Re:Not meant to be a lifetime achievement award by ptr2004 · · Score: 1

      Too bad they dont do the passage of time for peace prize. I am sure Gandhi would have been a good candidate

  21. Re:A Chem Nobel Prize that actually goes to chemis by Dionysus · · Score: 2, Informative

    Well, that's OK. 2004 Peace prize went to the an environmentalist who thinks AIDS is a bio-weapon created by bad western white scientists.

    --
    Je ne parle pas francais.
  22. Misread that by thc69 · · Score: 1
    He wants to live reclusively
    I misread that as "recursively".
    --
    Procrastination -- because good things come to those who wait.
    1. Re:Misread that by ModMeFlamebait · · Score: 1

      I misread that as "recursively".

      I misread that as "recursively".

      --
      Pavlov. Does this name ring a bell?
    2. Re:Misread that by vrt3 · · Score: 1

      Where are the Nazis when you need them? We should invoke Godwin, since every recursive thread needs a stop condition.

      --
      This sig under construction. Please check back later.
  23. Heros by Anonymous Coward · · Score: 1, Insightful

    In the end, the work these people do will mean much more than who put a puck in a net, a ball in a basket, or a jaunty tune in the public's ear.

    If mankind has any sort of saviour these days, it's these sort of men: scientists who give us the tools to cure blindness, disease, hunger, and poverty. I'd probably be dead today without technology; the survival rate for near-blind kids was pretty grim just a few centuries ago. Today, thanks to powerful eyeglasses, and later on, laser eye surgury, I've got a normal life.

    It's nice to see that these scientists are finally getting some recognition for the great work they do. I wish more scientists got more recognition, everyday, for the contributions to our collective knowledge and future happiness that they quietly make they make on a daily basis, despite a public who is apathetic or hostile to their efforts.

    To all the scientists out there on slashdot, thanks, and keep up the good work!
    --
    AC

    1. Re:Heros by Anonymous Coward · · Score: 0

      That's great! Of course they haven't actually come with a cure for anything you mentioned, your eye glasses were invented by a god fearing Christian centuries ago and the laser surgery you had is going to give you some really bad scar tissue problems - but hey, go science!!!

    2. Re:Heros by egoriot · · Score: 1

      Hear, hear! Scientists, mathematicians and engineers are the true engines of progress. An army of lawyers, politicians, financiers, athletes, musicians, and artists is not worth one of these individuals in the long run.

    3. Re:Heros by nagora · · Score: 1
      An army of lawyers, politicians, financiers, athletes, musicians, and artists is not worth one of these individuals in the long run.

      Let's not leave the clergy out of that list.

      TWW

      --
      "Encyclopedia" is to "Wikipedia" what "Library" is to "Some people at a bus stop"
  24. The Nobel Prize should really go to... by Anonymous Coward · · Score: 0

    The Nobel Prize for Chemistry really ought to go to the doctors who treated Señor Taco after he got the clap from those hookers in Juarez a few weeks ago.

    They had to concoct a special formula for him because they had never seen such a bad case of the clap before.

  25. Re:A Chem Nobel Prize that actually goes to chemis by drooling-dog · · Score: 1

    Yeah, the really BIG molecules have cornered the market on sex appeal, it seems. Still, there aren't too many things in science that are more challenging than a total synthesis of a complex natural product ("small" molecules by molecular biology standards) with a dozen or so chiral centers...

  26. Dumbing a complicated subject down by aphexbrett · · Score: 5, Interesting

    "Metathesis can be compared to a dance in which the couples change partners."

    This has to be the worst quote I've ever heard describing Grubbs' catalyst. When I woke up this morning and heard that Grubbs had won the Nobel I wondered what the brief description of his work was going to be, and I honestly have to say I was amazingly disappointed with it. However this is part of a larger problem that I've encountered often especially on this webpage, how do you explain complicated subjects to the uninformed masses? How do you explain detailed chemistry to computer geeks? In some cases a pretty simplistic idea is transferred successfully, but this is the exception rather than the rule. IMO, the comments left about the story tend to further complicate the matter.

    Having use chemistry developed by Grubbs I'll provide a brief description of his remarkable achievements in the field of organic synthesis (one of the serveral fields Grubbs has impacted [Grubbs is however an organometallic / inorganic chemist]). Organic synthesis is the study of building complext molecules from simple starting materials. The "goal" of organic synthesis is to make compounds with biological activity, e.g. new drugs. Many of the target compounds are initially isolated from nature, chemist then try to replicate them in the lab environment. One of the catalysts Grubbs developed allowed for synthesis of a particularly common structural feature (I'm thinking of cyclic structures, there are more, I know) and it opened whole new doors in terms of synthetic routes that one could take to complete a molecule. It was fairly evident in the mid 90s that his work had a huge impact on the synthetic community and it was apparent he would win the nobel, it was just a matter of time.

    1. Re:Dumbing a complicated subject down by danila · · Score: 1

      How do you explain detailed chemistry to computer geeks? In some cases a pretty simplistic idea is transferred successfully, but this is the exception rather than the rule.

      Well, you just answered your own question. You start from the basics that are understood by your intended audience and explain using accessible language, but without oversimplification. Each next concept following from the previous you gradually get to explain the topic at hand, like you brilliantly did. If more space/time is available, each step can be explained in more detail, but the magic rule is to start at the level of your audience (readers) and go from there. Intelligent people are capable of following the explanation and understanding arbitrarily complex concept.

      Thanks again for the great explanation. If only everyone was this considerate.

      --
      Future Wiki -- If you don't think about the future, you cannot have one.
    2. Re:Dumbing a complicated subject down by Anonymous Coward · · Score: 0

      Perhaps you just don't understand the complexities of a dance in which couples change partners!

    3. Re:Dumbing a complicated subject down by yuriwho · · Score: 1

      They should shave used an analogy like this:

      a conga line moving through a party, with a guy on the end of the line selectively inserting pretty women into his place at the end on the line, and then grabbing their waists and following the chain until another suitable female is found to insert. This continues until all suitable females have been added to the line.

      That at least accurately cartoons the ROMP reaction.

      --
      no sig.
    4. Re:Dumbing a complicated subject down by frozenraisin · · Score: 1

      "Metathesis can be compared to a dance in which the couples change partners."

      I found this particular description of metathesis to be the most accurate statement. If look at the overall transformation and consider each dancer to be an olefinic carbon, that's exactly what metathesis does. It's probably one of the easiest chemical transformations to explain to non-chemists.

  27. Re:A Chem Nobel Prize that actually goes to chemis by k98sven · · Score: 1

    What the heck does it matter who it goes to? It's the discovery that counts, not the academic background of the person who made it.

    Or don't you consider biochem to be part of chemistry? Because that's a pretty narrow-minded view of chemistry, especially considering how it's the area where the biggest things are happening.

  28. But who won for "Attempted Chemistry" this year? by elrous0 · · Score: 1
    I'll bet it was Pedro. Every since he got that truck he's been so damn cocky!

    -Eric

    --
    SJW: Someone who has run out of real oppression, and has to fake it.
  29. \o/ by Anonymous Coward · · Score: 0

    Äntligen!

  30. Re:A Chem Nobel Prize that actually goes to chemis by Anonymous Coward · · Score: 0


    The thought of it! the prize went to people who didn't have a guild card! The fact that they did top notch science is irrelevant. Someone should have checked their credentials first and leave their important discoveries to be looked at a later stage...

  31. Re:A Chem Nobel Prize that actually goes to chemis by Jonathan · · Score: 1

    Well, I'm a genomicist myself, and feel I have more in common with biochemists than I do with chemists -- it's not that I don't feel respect for biochemistry -- but to me chenistry is about general principles of chemical reactions, just like physics is about general principles of matter and energy. Of course, things like proteins certainly need to obey physical and chemical laws, but discoveries of how proteins work, as in last year's chemistry nobel, while certainly of great importance, don't really tell us any new basic facts about chemistry itself.

  32. Re:A Chem Nobel Prize that actually goes to chemis by Da_Biz · · Score: 1

    Wow, I thought you were joking, but...

    http://en.wikipedia.org/wiki/Wangari_Maathai#Contr oversy

  33. Pronounciation by AFairlyNormalPerson · · Score: 1

    TFA says that the word "metathesis" comes from the words "meta" and "thesis", so the reader could easily read the word as met.a.THE.sis (long E and emphasis on 3rd syllable); however, the only pronounciation I have ever heard is me.TaTH.e.sis (short a and emphasis on the 2nd syllable). Just FYI.

  34. Re:A Chem Nobel Prize that actually goes to chemis by k98sven · · Score: 1

    -- but to me chenistry is about general principles of chemical reactions, just like physics is about general principles of matter and energy.

    Well, that's your problem then.. it's a narrow view. By that rationale, you would have very very few Nobel prize winners in either Physics or Chemistry.

    E.g. this year's Physics prize doesn't teach us anything new about the "general principles". It's all explainable in terms of Quantum Mechanics and Maxwell's equations. That doesn't mean it's not physics.

    Of course, things like proteins certainly need to obey physical and chemical laws, but discoveries of how proteins work, as in last year's chemistry nobel, while certainly of great importance, don't really tell us any new basic facts about chemistry itself.

    Neither does this prize. All of chemistry is explainable within the framework of quantum mechanics. It's like complaining that the Physics prize isn't teaching us anything new about QM (or newtonian mechanics for that matter).

    Besides which, that's bull. Catalysis is catalysis and it pertains to perhaps the most central part of chemistry there is, namely "How do chemical reactions occur". Why would it be less interesting to chemistry just because an enzyme is doing the catalysis?

    In fact, it's just the other way around! Enzyme catalysis is an area which is vastly more complex and vastly less understood than traditional catalysts. Not to mention there is significant cross-over between the areas of metalloorganic catalysts (such as this prize) and enzyme catalysis. Try googling for "biomimetic catalyst".

  35. Re:eat it by Anonymous Coward · · Score: 0

    will do school skillet

  36. Re:A Chem Nobel Prize that actually goes to chemis by Rich0 · · Score: 1

    Well, sure a genomicist would have more in common with a biochemist than a chemist, just as a biochemist would have more in common with a chemist than an astronomer. There is essentially a continuum of physical and natural sciences, and biochemistry tends to fall in-between. Biochemistry itself is a pretty broad term, covering everything from splicing genes into plasmids and growing vats of bacteria and churning out recombinant proteins, to studying electrical conductivity of DNA molecules. The former is fairly separated from traditional chemistry, and the latter is almost indistinguisable from pure physical chemistry.

    You can find biochemistry programs in biology, medical, and chemistry departments - often in the same university. Each tends to cater to a general region on the physical-biological continuum.

    Chemistry is a very broad field, as is biochemistry. And you really can't understand metabolism without a good understanding of kinetics and thermodynamics - two very physical subjects. One way of looking at life is just a bunch of catalysts that carefully control the reaction of oxidizing and reducing agents in their enviornment, using the resulting energy to replicate, get around, and generally do useful things like speculating on what life actually is... :)

  37. Re:dupe by Anonymous Coward · · Score: 0

    Silence, dickhead. Take your pitifully unhumourous XML tags and stick them up your arse.

  38. Prof Grubbs in New Zealand by w.timmeh · · Score: 1

    I just spoke to my chemistry lecturer (University of Otago), after we briefly covered olefin metathesis in our organic course this morning. Apparently he is off to have a meal with Prof Grubbs in Christchurch, who will be giving a talk at Otago on Monday.

    1. Re:Prof Grubbs in New Zealand by Anonymous Coward · · Score: 0

      Unfortunately, it sounds like Grubbs might have to head back to the states on Sunday -- I wager he would offer his strongest apologies and that he'll try to get back to NZ sooner rather than later. Word is that he and his wife are enjoying their stay. (Your lecturer isn't Allan Blackman, is it? He's a good man.)

  39. Schrock father of Sun's Solaris kernel engineer by rrobles · · Score: 1
    Eric Schrock

    http://blogs.sun.com/roller/page/eschrock#to_my_fa ther

    Congrats to the high-tech family!
  40. Percy got shafted by the commitee again. by Boronx · · Score: 1

    Lord Percy: After literally an hour's ceaseless searching, I have succeeded in creating gold, pure gold.

    Blackadder: Are you sure?

    Lord Percy: Yes, my lord. Behold.

    Blackadder: Percy... it's green.

    Lord Percy: That's right, my lord.

    Blackadder: Yes, Percy, I don't want to be pedantic or anything, but the colour of gold is gold. That's why it's *called* gold. What you have discovered, if it has a name, is "green".

    Lord Percy: Oh, Edmund, can it be true, that I hold here in my mortal hand a nugget of purest green?

    Blackadder: Indeed you do, Percy, except, of course, it's not really a nugget, it's more of a splat.

    Lord Percy: Well, yes, a splat today... but tomorrow - who knows, or dares to dream?

  41. mod parent up [nt] by themusicgod1 · · Score: 1

    ntz0r!

    --
    GENERATION 26: The first time you see this, copy it into your sig on any forum and add 1 to the generation.