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Panel To Investigate Scientist For Cloning Claims

collegetoad writes "A panel of scientists from the Seoul National University will investigate scientist Hwang Woo-suk on whether he committed fraud in claiming he had developed tailored embryonic stem cells. From the article: 'Hwang also said in a paper published in 2004 in the journal Nature, that he had cloned, for the first time, a human cell to provide a source of embryonic stem cells -- master cells that can provide a source of any type of tissue or cell in the body.'" We've reported on this previously.

16 of 117 comments (clear)

  1. Sarbanes Oxley? by Doomedsnowball · · Score: 4, Interesting

    Is this the Enron of Biomed research? Do we need better accounting (of data and methods) like Sarbanes-Oxley? Just a thought.

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    1. Re:Sarbanes Oxley? by drewzhrodague · · Score: 4, Interesting

      No. Science takes care of its own, in its own way. THis is what peer review is for. Watch! They will get to the bottom of the dispute, scientifically, and then we will see what is really there, and what is bogus. Someone's got a tagline, about having a stable society when someone guns-down a schoolyard, and the laws don't change. Same kinda thing here, laws shouldn't even be involved, as their methodology will tell all -- eventually.

      --
      Zhrodague.net - I do projects and stuff too.
  2. Hopefully by vertinox · · Score: 4, Interesting

    Hopefully the panel will go out and actually try to reproduce his results rather than having a political debate of whether not it is.

    His business ethics are questionable, but if there is some truth to this then they should be able to follow a scientific method in order to prove or disprove the falsification of the findings.

    --
    "I am the king of the Romans, and am superior to rules of grammar!"
    -Sigismund, Holy Roman Emperor (1368-1437)
    1. Re:Hopefully by deacon · · Score: 4, Informative
      This whole story is old news by now.

      First, the data is know to be fake. From this link:

      http://news.pajamasmedia.com/world/2005/12/15/6683 762_Doctor_Cloning_P.shtml

      Roh also told MBC television that Hwang had pressured a former scientist at his lab to fake data to make it look like there were 11 stem cell colonies.

      In a separate report, a former researcher told MBC that Hwang ordered him to fabricate photos to make it appear there were 11 separate colonies from only three.

      "This is something I shouldn't have done," said the researcher, who was identified only by his last name, Kim, and whose face was not shown. "I had no choice but to do it."

      Second, from this link:

      http://science.monstersandcritics.com/news/article _1073161.php/Disgraced_Korean_cloning_pioneer_pres sured_woman_colleague

      It quoted the woman as saying she felt 'forced' to donate egg cells, having been told that if she did not do so her name would be removed from a research document published in 2004.

      I hardly need to make editorial comment on these facts. Those without ethics will continue to insist nothing is wrong. Those of us with ethics shudder with revultion and hope the guy never works in a postition of authority again.

  3. Re:The benefits being..? by ackthpt · · Score: 5, Informative
    Why bother investigating? Anything this guy has ever written should be trashed.

    What worries me most is anything he has said or done which casts doubt on his work or credibility will be ruthlessly employed by the opponents of Stem Cell Research, which will be of no actual good service to anymone except on a dogmatic approach.

    And then they will go on to assert that their word is beyond reproach.

    --

    A feeling of having made the same mistake before: Deja Foobar
  4. This is not what we need now by Schezar · · Score: 5, Insightful

    Anti-intellectualism is seeing a renaissance, and this will only serve as "evidence" for those who decry science, deny logic, and advocate flim-flam. Despite the fact that I see this as proof that the scientific method works (they've rooted out phony research), those with other agendas will cling to it as proof that "those scientists in their ivory towers" are wrong.

    Homeopaths, naturalists, new-age healers, dowsers, reflexologists, chiropractors, feng shui "experts," et all: they use any slip of a scientist to bolster their support from those who don't know better. It saddens me, but such is the nature of the game.

    Real scientists need to stand up and denounce frauds loudly and strongly whenever they appear. Too many otherwise learned men stand idly by while charlatans ply their wares to the unsuspecting.

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    1. Re:This is not what we need now by dada21 · · Score: 3, Insightful

      I'm not sure I agree with what you posted.

      First, I know my parents trusted scientists when they said carbs were good, margarine was good and butter was bad. The homeopaths were crying foul from day one, and have been decrying the previous Food Pyramid for years. Now it seems the natural foods freaks were right/

      Second, I know that scientists are just humans like you and I -- their income depends on being right more than being wrong. Cooked books would seem to be the norm, especially when public money is at stake. Remember the second hand smoke lies that were found wrong by the Supreme Court but are still being used today to ban smoking in restaurants? These were honored and respected scientists funded by public dollars -- and they lied.

      I'm guessing you'd call for licensing for scientists -- so we end up with the same high costs and low quality service we get in any licensed industry. I'm glad we have the "whack-jobs" of alternative medicine. I may not agree with what they have to say, but I know I want to see private industry competition to what is quickly becoming a public industry: science and the politicing that comes along with public funding of it.

    2. Re:This is not what we need now by Thunderstruck · · Score: 3, Funny

      Homeopaths, naturalists, new-age healers, dowsers, reflexologists, chiropractors, feng shui "experts," et all: they use any slip of a scientist to bolster their support from those who don't know better. It saddens me, but such is the nature of the game.

      All of these folks are vitaly important. Lets see if I can address them in turn*:

      1. Homeopaths - sexual orientation has not been proven to affect scientific ability.

      2. Naturalists - These are people who run around without clothes, right? Whats not fun about that?

      3. New-age Healers - Because after a year or two, the bottom of my shoe really needs to be replaced.

      4. Dowsers - I didn't get any money for marrying my wife, but if this practice is going to see a return, I can't complain.

      5. Reflexologists - These folks are a must, how else will we be able to develop the weapons we need to fight the Zentradi?

      6. Chiropractors - A good chiropractor sometimes costs less than a massage therapist, both give good back-rubs. Competition is good, we need Chiropractors.

      7. Feng Shui Experts - This is perhaps the most important of all, it helps keep my wife from re-arranging the furniture. "But honey, they HAVE to be arranged that way."

      --
      Trying to use sarcasm in text-based forums does not work.
  5. Why? by geneing · · Score: 4, Insightful
    There were several cases recently when high profile research results turned out to be fraudulent. What I can't understand is what were the authors thinking... Yes, it is possible to get a fraudulent paper accepted, but immediately dozens of other labs will be trying to reproduce the results and discover the fraud.

    I can believe that a third-rate paper published in a third-rate journal will not get much scrutiny from other researchers. However, these guys reported major results that many other labs were trying to achieve. What were they thinking?

  6. Re:The benefits being..? by vertinox · · Score: 5, Insightful

    Why bother investigating?

    Anything this guy has ever written should be trashed.


    The same could be said about Dr. Josef Mengele who commited far worse atrocities against humanity, but some of the kwoledged gain by his gruesome work is still used today in medical schools albeit as mear reference to the insides of a living being.

    One can acheive those kind of things when you are doing live vivisections on human beings.

    To throw away knowledge even if it was gained through horrible acts is almost as bad of a sin by trying not to better the world and correct wrongs with that knowledge. Its almost as if you declare those who were damned to this cruel fate, that their suffering and loss means nothing to the living and you are going to throw them away to the trash dump of history without trying to save another human life.

    --
    "I am the king of the Romans, and am superior to rules of grammar!"
    -Sigismund, Holy Roman Emperor (1368-1437)
  7. No by everphilski · · Score: 4, Informative

    Hopefully the panel will go out and actually try to reproduce his results rather than having a political debate of whether not it is.

    No. FTA: it would issue its final findings next week ... doubt they are going to raise stem cell lines from human tissue in a week...

    -everphilski-

  8. Trust but verify by digitaldc · · Score: 3, Insightful

    Female members of his team also said Hwang coerced them to donate their own eggs for his research.

    I can see him now..."Give me your eggs so I can scramble the data and we can all go down in disgrace."

    --
    He who knows best knows how little he knows. - Thomas Jefferson
  9. Re:Public vs Private Funding by vertinox · · Score: 4, Insightful

    When I decry public funding of science, I'm blasted because people say that the free market won't pay for certain research. Now I see a more evil side of it -- and I fear that we'll see more investigations like this if I'm right. What can we do to combat humanity's deep need for self preservation in a scientist having the same human drives, especially when it is funded straight out of our pocket involuntarily?

    There can be two sides to this issue.

    1. If the research is funded with government money, it can be influenced by politics.
    2. If the research is funded with private money, it can be influenced by its investors.

    Think of it like a global warming research sponsored by a congressman who is lobbied by an oil company vs a TCO of Windows vs Linux research sponsored by Microsoft.

    Both could have potential bias and complications.

    Personally, I believe both private and public research can be beneficial. Take DARPA for example. I for one believe DARPA is the shining example of public research gone right. It is backed by public money, but often uses the private sector as a major part of its research. Take the recent Grand Challenge for example.

    So I think there is a place for public funding at least to get the ground work. After all, the Manhattan and Apollo Project were publicly funded.

    However, if you believe government funded projects are a waste of your tax money, then you can do what I do... Donate to a private non-profit research group that is tax deductible. I realized if I donate enough money to either Wikipedia or the Singularity Institute I could just write off all my taxes next year. Even though I don't get more money than I would have not donating, it means the IRS will have to give me a larger refund, hence putting my money where I want it to go and not where a congressman does.

    --
    "I am the king of the Romans, and am superior to rules of grammar!"
    -Sigismund, Holy Roman Emperor (1368-1437)
  10. peer review is more than that by Quadraginta · · Score: 4, Interesting

    First of all, peer review functions in many places besides vetting articles for publication. Indeed, it's much more important in reviewing grant applications and in how and whether your colleagues direct good students and post-docs your way, since while publications are nice, it's successfully attracting research money and recruiting good employees that really counts. This guy is getting that kind of peer review now -- and greatly to his harm. So indeed the system is functioning as designed.

    More importantly, if you're saying the system is busted because it must sometimes punish fraud after it's published, instead of preventing its publication entirely -- well, then perhaps something needs to be clarified about the nature of scientific publication. A scientific journal is not a textbook. Stuff published there is current research, not accepted wisdom. It's not meant to be archival quality, things that folks will stake a reputation on. It's meant to be the "bleeding edge" of knowledge, so to speak, the latest and (necessarily) shakiest bit of possible insight. Reasonable people expect much that is published in a journal to turn out to be wrong, or incomplete. They don't ordinarily expect it to be a fraud, but it does happen on occasion, and reasonable people keep that in the back of their minds, too.

    In fact, one of the main reasons for scientific publication is to present new ideas and data to the widest possible audience, so that people who don't know, fund, or work for the original researcher have a chance to consider the merits and drawbacks of the idea, test it, challenge it, and prove or disprove it. You might reasonably think of scientific publication as more or less a "debugging" step of a new scientific idea, the process by which you submit some newfangled notion to the rigours of a bunch of "beta testers" (other scientists) who will bang on the idea, make sure it's sound.

    You would not, I hope, conclude that because spectacular bugs are sometimes found in software at the "beta" stage this means that the authors were wrong to release it at all. Having a large community of interested expert users cooperate in beta testing your software -- think open-source software -- can speed up the process of producing quality products greatly. That's exactly how scientific publication works.

  11. Re:The benefits being..? by c_forq · · Score: 3, Informative

    They are more devolped then embryonic, which is a good and bad thing (they can't become anything at this point, but that is partially good as embryonic cells can easily become tumors). They have proven useful in blood and marrow operations, and have started to show promise in other areas.
    Linky:
    http://times.hankooki.com/lpage/200411/kt200411261 7575710440.htm

    --
    Computers allow humans to make mistakes at the fastest speeds known, with the possible exception of tequila and handguns
  12. I don't quite agree by Quadraginta · · Score: 4, Insightful

    I don't think so. Let me tell you from 15 years of publishing in scientific journals, and reviewing the proposed publications of others, that there is no clear and sharp division between an "honest" mistake and a mistake into which you are led by bias, preconceived notions, or your personal feelings for another scientist whose work you are challenging or confirming. Scientists are human beings as much as the next person. Very few will deliberately and with malice aforethought falsify data. But plenty will talk themselves into believing that a certain dubious "correction" of the data makes sense.

    It's a lot like high-school chemistry lab, in which (if you were decently smart), you knew what the results of the lab should be. Does that affect the way in which you write down the data? You bet. You do the experiment once, and you get a result you "know" is crazy. So you say: "That can't be right, something must have gone wrong..." and you do it again. If you get the result you expect, then you tend to just write it down uncritically.

    Just expand that typical human behaviour to much more complex experiments, and you'll see what I mean. Grown-up scientists do an experiment, and they get a result that "can't be right," so they do it again until they get a result that "seems right," or they talk themselves into some kind of data analysis that "corrects" the raw data. Have a look here (warning: PDF link) for an interesting discussion of the case or Robert Millikan, who "framed a guilty man", in the phrase made immortal by the LAPD, by falsely presenting experiments that led to a correct scientific conclusion.

    The long and short of it is that the question of the "honesty" of the author of a publication is very much a gray area, and anyone who seriously just assumes that all the data from an experiment have been presented, and all the data analysis has been done in completely neutral way, without any influence of preconceived notions, is a fool. You must assume that the personal predispositions of the scientist doing the work had some influence on the experimental data reported. This isn't meant to be pejorative -- I'm not saying you assume other scientists are routinely dishonest. You just assume they're human, and may have fooled themselves or have a bit of an agenda when they present their data, and you take that into account. Healthy skepticism is the order of the day. That's why we like to see even experiments that seem completely unexceptional and from scientists of unimpeachable reputations repeated several times by a broad range of other workers before we accept them.

    I certainly agree deliberate fraud is way out of any "gray area" about the motivations of the scientist submitting articles for publication. (And that's why the punishment for doing so is far, far harsher than for simply making an "honest" mistake, or even a mistake into which you are led by bias or incompetence.) But there is no way one can, or should, draw a sharp line between completely unconscious error and semi-conscious half-deliberate fudge, and it would be a great error for anyone to blindly assume that the data in any scientific publication is beyond question.