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Tumor Suppression Gene Discovered

An anonymous reader writes ScieceDaily is reporting that researchers at Ohio State University may have identified a new and unusual tumor suppression gene that could effect cancers of the lung, head, and neck. From the article: "The gene, known as TCF21, is silenced in tumor cells through a chemical change known as DNA methylation, a process that is potentially reversible. The findings might therefore lead to new strategies for the treatment and early detection of lung cancer, a disease that killed an estimated 163,510 Americans in 2005. The study could also lead to a better understanding of the molecular changes that occur in tumor cells during lung-cancer progression."

4 of 129 comments (clear)

  1. Effect by HermanAB · · Score: 4, Insightful

    Gee, why would anyone want to effect cancer? I would think there are enough carcinogens out there to effect cancer already.

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    Oh well, what the hell...
  2. Oncology epidemiology and methylation... by CupBeEmpty · · Score: 4, Insightful

    ..are areas that I have worked in, at the Sloan-Kettering Cancer Center in NYC. I am not really that enthusiastic about this find. There are an enourmous amount of "cancer supressing genes" but very few yield useful clinical results. This seems to be a case of over-hyping (which occurs all the time) of a scientific find.

  3. Re:good news for me (and you) by Voltageaav · · Score: 3, Insightful

    Don't forget emphysema. I think that's a tad worse than discolored teeth, or the stench that surrounds you.

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    Someone save me from this sanity.
  4. Re:good news for me (and you) by ross.w · · Score: 4, Insightful

    A quick survey of my four grandparents, while a small sample, is enlightening.

    Maternal Grandmother
    Sendentary job, never smoked. developed diabetes at age 70, constant blood pressure problems - died age 84 after years of suffering strokes

    Maternal Grandfather
    Athlete and Gallipoli Veteran - Not a smoker to my knowledge. Suffered with high blood pressure and died age 84 due to complications from Parkinson's disease.

    Paternal Grandmother
    Overweight to the point of obesity. Gave up smoking when in her 40s
    Died age 71 from complications resulting from Type 2 diabetes.

    Paternal Grandfather
    Stevedore and tennis coach. Smoked all his adult life until age 78. Always has two schooners (large glass) of beer every evening. Recently celebrated his 90th birthday. Suffers from Emphysema (not yet on oxygen) which will probably eventually kill him.

    From this small sample, it appears that lack of fitness will kill you just as quick if not quicker than smoking.

    So Slashdotters, instead of poking fingers at the smokers, get up, turn off your computer, get out from your Mother's basement and go for a walk. It might save your life.

    (I don't smoke btw)

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    If my call is important, why am I talking to a recording?