Slashdot Mirror


Study Explains Evolution's Molecular Advance

pnewhook writes "The New York Times is reporting that 'by reconstructing ancient genes from long-extinct animals, scientists have for the first time demonstrated the step-by-step progression of how evolution created a new piece of molecular machinery by reusing and modifying existing parts. The researchers say the findings, published today in the journal Science, offer a counterargument to doubters of evolution who question how a progression of small changes could produce the intricate mechanisms found in living cells.'"

20 of 477 comments (clear)

  1. Matter of time by Transcendent · · Score: 5, Insightful

    It was only a matter of time before scientists discovered the steps and had enough knowledge to connect the dots.

    Frankly, I'm glad they're finding more and more of how biology works. I don't want to get into a creationist debate, but it has always astounded me that people would argue that life is too complex for it to have been made "naturally" and that a higher being must have helped along the way. But, by saying that, they're saying that God is not powerful enough to create such a universe in which evolution can happen, that a universe created by God could not possibly work by itself.

    How dare they...

    1. Re:Matter of time by dsanfte · · Score: 5, Interesting

      It's also immensely disrespectful to our ancestors of well over a million years' span, to deny their existence because it just might, maybe rock the boat a little.

      How many thousands of generations of people lived and died over the millennia so that we might be where we are today? And some would deny their very existence. Shame on you!

      --
      occultae nullus est respectus musicae - originally a Greek proverb
    2. Re:Matter of time by shawb · · Score: 5, Interesting

      To be fair, evolution does not disprove of A god...

      But it does kinda reduce the likelihood that there is a PERSONAL god who is intimately concerned with all of our activities, and so is a reason to behave in a moral way and more importantly, to then worship that god and tithe to the church who claims to be the bridge between man and god.

      (Note, I was not saying that atheists are not moral with the "is a reason to behave..." line, but for some people the existance of a personal god is one of the reasons to behave in a moral manner.)

      --
      I'll never make that mistake again, reading the experts' opinions. - Feynman
    3. Re:Matter of time by plunge · · Score: 5, Insightful

      Not at all. I'm an atheist, but I welcome imaginative, honest theist thinkers like biologist Kenneth Miller who feel that, if anything, evolution BETTER fits this theology than the reverse. A universe in which God allows to develop on its own, and then reaches out PERSONALLY to sentient creatures (and even performs miracles as part of this reaching out) is far more "free" than one in which God is constantly micro-managing.

      Now, I don't believe in God, but I bear no grudges against those who do, and as long as a belief doesn't involve scientific claims or attacking good science with falsehoods, but I applaud those who are taking their beliefs forward and refining them to make them more honest rather than simply defending dogma. If there were a God, the only kind I can possibly imagine would reward the former, not the latter.

    4. Re:Matter of time by geeber · · Score: 5, Interesting

      To be fair, evolution does not disprove of A god...

      But it does kinda reduce the likelihood that there is a PERSONAL god who is intimately concerned with all of our activities, and so is a reason to behave in a moral way and more importantly, to then worship that god and tithe to the church who claims to be the bridge between man and god.


      Personally, I feel like events such as hurricane Katrina, the tsunami in the indian ocean, and September 11th offer a much stronger proof of the lack of a personal god.

      Interestingly, other people look at the same events and come to the exact opposite conclusion.

      Wierd, no?

    5. Re:Matter of time by Daniel+Dvorkin · · Score: 5, Insightful

      Another is to point out evolution's flaws (something evolutionists get very testy about, btw. They don't like their faith questioned anymore than religious people do)

      This is simply not true. Evolutionary biologists find flaws in existing theories of evolution fairly often, and the theories are adjusted accordingly over time. This is simply how all science, including biology, works; there is no crisis of faith as you claim.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    6. Re:Matter of time by plunge · · Score: 4, Insightful

      "Another is to point out evolution's flaws (something evolutionists get very testy about, btw. They don't like their faith questioned anymore than religious people do)"

      It's easy to make this accusation, but intellectually lazy.

      I'd say that scientists spend more time picking apart each others flaws and mistakes than in almost any other realm of life. What they get testy about is people who haven't bothered to actually study the debates, who know next to nothing about the subjects they are talking about, spreading falsehoods or gross misrepresentations of science. Worse, even when these ideas are debunked or even admitted as wrong by the people making them, they then still get brought up over and over again to new audiences. How many times have you heard the "evolution can't add new information" or "if we evolved from apes, how come there are still apes" nonsense? If people seemed determined to spread lies and falsehoods about me personally, I'd certainly get "testy." But not because anyone was questioning my "faith."

      So I think your accusation is in very poor form.

    7. Re:Matter of time by plunge · · Score: 5, Interesting

      That was actually the subject of this great, award winning blog post on Pharyngula:

      "The proper reverence due those who have gone before"
      http://scienceblogs.com/pharyngula/2006/01/the_pro per_reverence_due_those.php

    8. Re:Matter of time by monoqlith · · Score: 5, Informative

      Sorry to nitpick, but quantum "fluctuations" are not random. People often confuse the terms "random" and "probabilistic" when they talk about quantum physics. A "random" system is a system where any outcome of measurement is just as likely as any other outcome. However, quantum particles are more likely to be at the expectation value of position than at any other place, though there is a NON-zero probability of it being anywhere else in the system. So quantum "fluctuations"(I'm not sure what you mean by this) are NOT random, because some outcomes of measurement are vastly more likely than others. The only requirement for a quantum particle is that the probability of it being SOMEWHERE is 1.

      Quantum particles are associated with probability WAVES that fluctuate with time. When we say wave-particle duality we mean that the particle does NOT have a definite classical trajectory but instead a WAVE of probability associated with it that describes the positions, energies, and momentums at which the particle is most likely to be. This is called a wave function; it is a solution to Schrodinger's differential wave equation and its square is a probability curve.

      Depending on your interpretation, quantum mechanics does indicate some things about reality such as there is an ONTOLOGICAL limit on what we can know for certain about objective reality such that it appears meaningless to talk about an absolute objective reality at all. That is, reality changes by being observed. However, unlike general relativity which does indeed EXPLAIN gravity by saying that gravity is identical with a curved space-time geometry, you are quite right in saying that quantum mechanics does not explain anything. Nor does particle theory or E&M explain why there are electric and magnetic forces without beginning to conjure up force-carrying particles and the like. They are currently trying to explain all these things by means of string theory.

  2. Re:God created everything... by Fulcrum+of+Evil · · Score: 5, Insightful

    There is nothing without God.

    This is a science discussion - proselytizing has no place here.

    --
    "We returned the General to El Salvador, or maybe Guatemala, it's difficult to tell from 10,000 feet"
  3. no by Khashishi · · Score: 4, Insightful

    They aren't saying that God is not powerful enough to create a universe with evolution. They are saying God didn't create a universe with evolution. Significant difference there

  4. Re:Annoying.... by TubeSteak · · Score: 4, Insightful
    Dr. Behe described the results as "piddling." He wondered whether the receptors with the intermediate mutations would be harmful to the survival of the organisms and said a two-component hormone-receptor pair was too simple to be considered irreducibly complex. He said such a system would require at least three pieces and perform some specific function to fit his notion of irreducibly complex.

    What Dr. Thornton has shown, Dr. Behe said, falls within with incremental changes that he allows evolutionary processes can cause.

    "Even if this works, and they haven't shown that it does," Dr. Behe said, "I wouldn't have a problem with that. It doesn't really show that much."
    He will never give up as long as he can keep moving the goalposts.

    It's truly an intellectually dishonest practice and it speaks directly to the kind of Doctor Behe is. This is the guy who testified in that 'lets put ID into the classroom' trial in Dover, PA. His testimony was an embarrassement and I'm surprised he has enough credibility left that the NY Times would include him in their article. I guess it's the whole "two sides of an argument" theme again.

    Here's a great astronomy example of almost the exact same thing.
    http://www.anomalist.com/commentaries/claim.html
    Rather than having two images of the same object, astronomers now randomly decided that three were necessary.
    --
    [Fuck Beta]
    o0t!
  5. Re:Waiting... for God? by From+A+Far+Away+Land · · Score: 4, Funny

    If the Great Creator Spaghetti Monster wanted you to read the article, he'd have provided you with a free registration.

  6. Re:God created everything... by Expert+Determination · · Score: 4, Insightful
    You are a moron. Before I'm modded down as flamebait I shall justify that statement.

    When science thinks they understand something, credit should be made to God.
    Science is not a person. Science is not plural.

    But God has been here FOREVER!!
    Just saying this in capital letters doesn't make it so.
    He has been proven to be true.
    Propositions or sentences are proven to be true. 'True' isn't an adjective that can be applied to characters from mythology. Maybe you mean "He has been proven to exist." But your inability to construct meaningful sentences is already losing you credibility.
    Unlike any other religion or science...
    What is the subject of this sentence? Are you saying that Christianity, the religion, sent Jesus. Or that God did? Do you have any idea what you are saying and how to construct a sentence.

    Nobody else can say their God walked the earth except Christians.
    Anyone can say that. Watch my lips "The evil God Urgzal, eater of babies, walked on Earth".

    Anyway, it was pretty easy demonstrating what a moron you are. You have demonstrated an inability to think beyond what most 5 or 6 year olds can achieve.

    I'd dismiss you as a troll but as I've seen so much evidence that many people do 'think' like you I'm taking you seriously.

    --
    "The White House is not an intelligence-gathering agency," -- Scott McClellan, Whitehouse spokesman.
  7. ID already mathematically incoherent by plunge · · Score: 5, Interesting

    It's worth noting that most mathematicians already think ideas like Irreducible Complexity and Complex Specified Information are a load of hooey, despite the appeals people like Dembski and Behe make to having made innovative breakthroughs in these areas:

    One good blog on this subject I've found is Good Math, Bad Math, and some posts relevant to this topic are:

    -CSI is basically incoherent: if you translate the definition of CSI into non-obscure words, it essentially boils down to either "something that contains a lot of information, but doesn't contain a lot of information" or a definition for which EVERY piece of information is specified:
    http://goodmath.blogspot.com/2006/04/one-last-stab -at-dembski-vacuousness.html

    -IC, when translated into math, makes no sense. We can actually PROVE in math that there is no general proof that some system is the simplest possible (which IC requires), much like we can prove that we can never solve the halting problem.
    http://goodmath.blogspot.com/2006/03/problem-with- irreducible-complexity.html

    -Even if they did make sense, CSI and IC basically conflict with each other, arguing contradictory things:
    http://goodmath.blogspot.com/2006/03/conflict-betw een-ic-and-it-arguments.html

  8. Reducible Complexity by posterlogo · · Score: 4, Informative
    The study is a fascinating one. If you have a subscription to Science, I suggest reading the summary of the research by Cristoph Adami termed "Reducible Complexity." I'm sorry I don't know how to get that article to those without a subscription but I can give a lay-man's summary here. Although the original research did not specifically mention evolution vs. intelligent design, they essentially disproved the central tenet of ID, that of "irreducible complexity." IC states that some things are so complex, they look like a "lock and key" mechanism -- one could not have be made without the other "in mind" -- thus they must both have been designed. The research that is the focus of this article described two different hormones with two different receptors. Both look like lock and key systems. By tracing evolutionary lineages, the authors of the study showed how a series of mutations, as little as 2, occuring sequentially by random could have led to the two divergent lock and key systems from a single precursor. As an academic biologist, I really think this elegant study is one of the nicest pieces of evolution research to come out recently. It truly addresses a problem even Darwin admitted was a caveat (though Darwin also offered the solution, which was indeed confirmed here).

    The solution is that the original precursor gained the ability to bind a new hormone by a single point mutation, and this did not disrupt the ability of it to bind its old hormone. The new receptor then diverged and through a well known process of gene duplication, begat multiple and independently evolving molecules. One retained the function of binding the old hormone, whereas another mutated further to lose the ability to bind the old hormone and could now only bind the new hormone. Viola -- two seemingly "designed" systems out of one precursor -- evolution at its finest, and IMHO, damning evidence against the basic principle of Intelligent Design.

    On a personal note, it never fails to amaze me how much people deny the intelligence of humans to figure things out... the old "just because we can't explain it now, it must have be an unexplicable force, like God." I'm sure lightning and earthquakes seemed supernatural too. Evolution is no different -- it can be dissected and explained.

  9. Re:Why do we still care about the doubters? by localman · · Score: 4, Insightful

    Speaking of sheltered lives...

    I'm a high school dropout and I'm both an athiest and I subscribe to evolution. I know a lot of college graduates who are very sharp and intelligent and yet don't accept evolution and believe in god.

    Really, I think that the choice on this matter is often dicated by emotion, which overrides any intellectual consideration or presentation of facts. Some people are afraid of there not being a god, or don't like the feeling of not knowing the purpose of life, or just like sharing beliefs with their friends and families, or don't like to admit they've been wrong for the past forty years, etc.

    And these people are important: they make up more than half of the voting population in my estimation so they have a profound effect on you and I. So don't dismiss them. And don't bother trying to convert them. But find a way to live with them. You may even find some of them make good friends.

    Cheers.

  10. Not going to dissuade the intelligent designers by mcc · · Score: 5, Insightful
    A bit of context, for the record:

    The reason the NYT is giving this the "doubters of evolution" spin is that there's this guy, Michael Behe, who wrote a book around 1995 somewhere called "Darwin's Black Box". The central idea of that book was the allegation that evolutionary science treats the cell like a "black box" that nobody attempts to look inside or explain. Evolutionary science, said Behe, only concerns itself with larger structures, and only assumes the stuff inside the cell "just works". Because evolution can't explain, subcellular structures, evolution lacks a foundation, is built on nothing, and is wrong.

    This is, of course, silly if you're actually familiar with the science, because to whatever extent scienists ever treated the cell like a "black box", it was because we didn't know how to look inside yet. Viewing machinery the size of a molecule is really hard. Scientists could analyze things, but have only relatively recently gained the ability to view the full picture of things, much as they might have wanted to.

    Once the technology for understanding the molecular structures that make up cells really started to take off (say, at the beginning of the 80s-ish), a revolution of sorts started in microbiology and genetics. And as this happened, Behe managed to exploit a neat trick of timing; he wrote his book just as a lot of fascinating questions were appearing through this revolution in microbiology, but before (since the questions had only just been asked) we really knew what the answers were. Behe was able to craft the illusion, since we didn't know the answers to some of those questions yet, that the questions didn't have answers or would never be answered and thus evolution was flawed-- not mentioning that work was underway or even partially completed to find answers to all of these questions. In the time since Behe wrote his book, cell microbiology has progressed by leaps and bounds, but the book itself is able to do a neat little job of making it seem like the cell really is just an inexplicable black box, because he wrote it just as science totally finished picking the lock.

    Which brings us to this story: The one scientific "big idea" in Darwin's Black Box was what Behe calls "Irreducible Complexity", and the publication of Darwin's Black Box was the main way this idea was popularized. The idea behind irreducible complexity is that there exist structures that contain one or more parts, and that if you remove one of the parts, the entire thing stops working. But one would expect that evolutionary mutation can only change "one thing" at a time; the idea that a single new allele that could simultaneously create two separable and interlocking structures seems wholly unbelievable. So how did irreducibly complex structures evolve?

    This is an extremely reasonable question, and one evolutionary science is obligated to answer. The problem is that Behe, and the rest of the ID crowd:
    1. Instead of asking the question, "how did irreducibly complex structures evolve?", skipped the question and immediately jumped to the conclusion "it is impossible for irreducibly complex structures to evolve".
    2. Even after answers to the question saying "this is an explanation of how irreducibly complex structures can evolve" were provided again, and again, and again, kept doggedly insisting "it is impossible for irreducibly complex structures to evolve".

    The answer to how irreducibly complex structures could evolve is pretty simple: all that would have to happen is for a structure to change its purpose over time. That is to say, it doesn't matter that irreducibly complex structures can only evolve one part at a time, because it is simple to imagine each of the small structures in an irreducibly complex system independently evolving for some other purpose than the big IC system performs, then being adapted into a bigger IC system with rube goldberg style ingenuity, then gradually losing the ability to function for their original purpose indepen

  11. Re:Cultural Evolution, and Nationalism Reborn,Anyo by shmlco · · Score: 4, Insightful

    "Dismissing the existence of God in no way advances the human condition."

    You mean other than removing the need for some to kill the non-believers and heretics in "his" name?

    --
    Any sect, cult, or religion will legislate its creed into law if it acquires the political power to do so.
  12. Re:Why do we still care about the doubters? by Alsee · · Score: 4, Insightful

    Using genetic algorithms, if I randomly write bytes at 10M/sec to a hard disk long enough, I will eventually produce Windows Vista

    You have no idea what you are talking about.

    Genetic Algorithms are *NOT* about a million monkeys typing random garbage until you stumble upon the complete works of Shakespeare. You reveal a complete ignorance of what Genetic Algorithms are and how they work when you suggest such a thing.

    I am a programmer and I have personally used Gentic Algorithms in the past. I have personally witnessed just how FAST they spontaneously generate information. How FAST they generate complex structured information. Sometimes they demonstrate slow steady improvements, and sometimes they generate huge leaps and bounds in solving problems.

    The process by which evolution creates information is well understood, and has been the subject of many mathematical papers. The FACT that the evolution process can be harnessed to create information and solve problems has been extensively observed, documented, and USED in real industrial applications. In fact the Genetic Algorithms evolution process has been used to create new better more efficient jet engine designs, designs better and more efficent than any human expert has ever been able to design.

    Genetic Algorithms are a powerful tool in the programmer's bag of tricks, and I highly reccommend that any and all programmers learn and explore them. Any programmer can easily witness ad understand for himself exactly how evolution is an information processessing system, and an information creation system. Can witess for themselves exactly how evolution can and does create information. Just pick up any book on Genetic Algorithms, or use Google to find any of the excellent websites on the subject.

    And anyone who claims that evolution does not or cannot create information, well they are flat out Wrong and Ignorant. It's as silly as someone claiming that man can never build a heavier-than-air fling machine AFTER scientsists have understood and built and witnessed such machines working.

    I've built it. I've witnessed it. And anyone who doubts it is absolutely invited to study Genetic Algorithms and understand it themselves and built it themselves and witness it themselves.

    People who say evolution cannot create complex information and cannot produce the complexity of life we see today, those people warrant as much respect as someone claiming flying machines are impossible.

    A sun-centered solar system explains the mechanism that divides the light from the darkness. It is absurd for anyone to suggest that a sun centered solar system in any way says or means that God does not exist. Nuclear fusion explains the mechanism that creates light for the earth. It is absurd for anyone to suggest that nuclear fusion in any way says or means that God does not exist. Optics explains the mechanism that creates rainbows. It is absurd for anyone to suggest that optics in any way says or means that God does not exist. And evolution explains the mechanism that creates the diversity of life on earth. It is absurd for anyone to suggest that evolution in any way says or means that God does not exist.

    Anyone who suggests that evolution and God are in any sort of conflict is as bad as the crackpot fundamentalist idiots who had Galileo imprisoned for life when he said that the earth moves around the sun. The fact that so many people are replaying this exact same nonsense today is an absolute embarrassment.

    -

    --
    - - You can't take something off the Internet! That's like trying to take pee out of a swimming pool.