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Advances in Bio-weaponry

kjh1 writes "Technology Review is running an eye-opening article on how biotechnology has advanced to the point where producing bio-weapons that were once only possible with the backing of governments with enormous resources is now possible with equipment purchased off eBay. You can now purchase a mini-lab of equipment for less than $10,000. The writer also interviewed a former Soviet bioweaponeer, Serguei Popov, who worked at the Biopreparat, the Soviet agency that secretly developed biological weapons. Popov has since moved to the US and provided a great deal of information on the types of weapons the Soviets were developing."

32 of 279 comments (clear)

  1. at last by Davey+McDave · · Score: 5, Funny

    A WMD that's marketed specifically for evil geniuses that are on a tight budget. The days of cheap minion labour are behind us, guys, gotta look after the pennies.

    --
    I've got the spirit, lose the feeling.
  2. Oh goody by AoT · · Score: 3, Insightful

    And I don't even trust the people who have access to bio-warfare now.

    1. Re:Oh goody by arivanov · · Score: 4, Insightful

      You should not.

      Everyone and his dog has access to bioweapon design and production capabilities. Once you have got your hands on a sample of virulent bacteria like Antrax producing them is a piece of cake. Viruses are considerably more tricky but it is still feasible to produce the less fussy ones with student lab level equipment. Actually with viruses your biggest problem would be isolation, not production.

      So far so good, here everyone would ask why all the dictator wannabies and terrorists are not slugging each other with biowarfare?

      Well the answer is simple, while producing bioweapons can be done in a garage, producing a viable delivery system is something much more difficult. Testing it is even more difficult. This is clearly beyond the capabilities of most terrorists and dictatorships out there. And thanks $DEITY, otherwise we all would have been walking around wearing filter masks and wearing biowarfare suits on public transport.

      --
      Baker's Law: Misery no longer loves company. Nowadays it insists on it
      http://www.sigsegv.cx/
  3. Ten grand? by MyLongNickName · · Score: 5, Funny

    Heck for $2.50, I can go to Taco Bell and be a WMD the rest of the day.

    --
    See my journal for slashdot ID's by year. Mine created in 2005. http://slashdot.org/journal/289875/slashdot-ids-by-year
    1. Re:Ten grand? by iamdrscience · · Score: 4, Funny

      Taco Bell = Weapon of Ass Destruction.

    2. Re:Ten grand? by temojen · · Score: 4, Insightful

      Can of tuna packed in oil $0.65 . Garden soil: free. Warm spot on top of your refrigerator: free

      Some way to aerosolize the resulting cocktail of anthrax and botulotoxin: ... I have no idea. Maybe that's where the $9999.35 comes in.

  4. worried? by joe+155 · · Score: 4, Insightful

    I wouldn't worry about terrorist implications of this, it is actually very difficult for a group without large resources (and even for those with them) to create workable weapons of mass destruction and bioweaponry would deffinately fall into this catergory... From a journal article i read by J. Mueller in Terrorism and Political Violence (vol.17:487-505, 2005)

    Aum Shinrikyo, a Japanese cult that had some three hundred scientists in its employ and an estimated budget of $1 billion, reportedly tried at least nine times over five years to set off biological weapons by spraying pathogens from trucks and wafting them from rooftops, hoping fancifully to ignite an apocalyptic war. These efforts failed to create a single fatality--in fact, nobody even noticed that the attacks had taken place.

    --
    *''I can't believe it's not a hyperlink.''
    1. Re:worried? by hazem · · Score: 3, Insightful

      According to a report on the CDC website (http://www.cdc.gov/ncidod/eid/vol5no4/olson.htm), 12 people died in the attack on the subway.

      By the end of that day, 15 subway stations in the world's busiest subway system had been affected. Of these, stations along the Hbiya line were the most heavily affected, some with as many as 300 to 400 persons involved. The number injured in the attacks was just under 3,800. Of those, nearly 1,000 actually required hospitalization--some for no more than a few hours, some for many days. A very few are still hospitalized. And 12 people were dead.

    2. Re:worried? by thedletterman · · Score: 3, Insightful

      That billion was spent paying scientists, not buying lab equipment. I could likely use my local university chemistry lab to engineer bio weapons.. given the right materials and technical knowledge.

      --
      Any fool can criticise, condemn, and complain, and most fools do. - Benjamin Franklin
    3. Re:worried? by joe+155 · · Score: 3, Informative

      I think sarin is a chemical weapons as opposed to a biological one

      --
      *''I can't believe it's not a hyperlink.''
  5. Also check out Ken Alibek by Entropy · · Score: 4, Informative

    He was deputy chief of science opperations at one of the USSR's main bioweapons facilities, and has detailed much of this experience in "Biohazard".

    Frankly, this is the stuff of horror stories.

    --
    The sea changes color, but the sea does not change.
  6. National Raygun Association by Dr.+Eggman · · Score: 4, Funny

    And that's why I don't go anywhere without my mutated anthrax

    ...for Duck hunting!

    --
    Demented But Determined.
  7. Move Along by dteichman2 · · Score: 4, Insightful

    Nothing to see here. Good article, but the point made is fairly worthless. Technology is getting better and cheaper. Why is it suprising that it should extend to the field of biotech? If the dude next door wants to whack you, I don't think that he needs to produce a virus to do it. I'm pretty sure that guns are still more economical and efficient for personal enterprise of this sort.

    --


    Silence is golden... and duct tape is silver.
  8. My girlfriend just peeked over my shoulder... by Dante+Shamest · · Score: 5, Funny

    GF: Why are they writing about the Soviets in the past tense?
    Me: Er, because they're in the past?
    GF: Huh?
    Me: Um, the Soviet Union collapsed more than a decade ago. Didn't you know that?
    GF: Get out of here! I thought China was still around.
    Me: Honey, the Soviet Union is modern day Russia. Not China.
    GF: What? I thought Soviets were commies, and the Chinese are commies.
    Me: Yes, but the Soviets were Russians.
    GF: The Russians are Chinese?
    Me: No! NO! NOO!
    GF: Jesus. You don't have to yell! I was just asking!
    Me: Alright, alright, I'm sorry.
    GF: So how do the Nazis fit into all this?
    Me: NAZIS!? Are you pulling my leg?
    GF: I'm not!
    Me: ...then I'm leaving you.
    GF: ...

    You can't make this shit up I tell you.

    1. Re:My girlfriend just peeked over my shoulder... by pjt33 · · Score: 4, Funny
      You can't make this shit up I tell you.
      You're posting on Slashdot on Sunday afternoon / evening claiming to have a girlfriend, and you say you're not making it up?
  9. That was the first and only... by Cyno01 · · Score: 5, Informative
    Yes, sarin is a nerve gas. And think about it, they pumped a bunch of poisin gas into a confined space with thousands of people, and managed to kill a total of 12. And this is the largest scale terrorist chemical attack ever!

    From wikipedia:
    The first successful use of chemical agents by terrorists against a general civilian population was on March 20, 1995. Aum Shinrikyo, an apocalyptic group based in Japan that believed it necessary to destroy the planet, released sarin into the Tokyo subway system killing 12 and injuring over 5,000. The group had attempted biological and chemical attacks on at least 10 prior occasions, but managed to affect only cult members. The group did manage to successfully release sarin outside an apartment building in Matsumoto in June 1994; this use was directed at a few specific individuals living in the building and was not an attack on the general population.


    Sucessful dispersal of chemical and biological agents is tough. Government funded programs have not been very effective, what makes anyone think that terrorists could come up with an effective delivery system.
    --
    "Sic Semper Tyrannosaurus Rex."
    1. Re:That was the first and only... by killjoe · · Score: 4, Insightful

      It doesn't have to be effective. If they did it five times and killed one person each time the population would be effectively terrorized. The purpose of terrorism isn't to kill people per-se. It's to scare them into some sort of action. Most people are perfectly happy to let any situation ride as long as it doesn't effect their daily lives. The terrorists seeks to effect the daily life of a fat dumb and happy or at least create the perception of the effect.

      --
      evil is as evil does
    2. Re:That was the first and only... by JDevers · · Score: 3, Insightful

      While I understand your sentiment, professionally designed WMDs can be very dangerous and are very effective. Tell me that a 10 kiloton nuke couldn't kill thousands of people with almost no planning and hundreds of thousands with only a marginal plan. There is a big difference between a terrorist organization and a government though. There isn't just the money, there is the rationale and expertise. Terrorists want to be showy, if it isn't scary to think about it isn't terrorism. Governments don't really care about being showy (well, they do, but in the large political scale not in the "every shot counts" way). A crate of CO2 tubes let go in a dense subway tunnel would kill a lot more than 12 people, but it isn't nearly as scary as a sarin gas attack. Just like the concept of a suitcase nuke is so much more scary the the one in the back of a semi truck. It takes top notch engineering to make a small and clean nuke, it takes a library card, some electricians, and some uranium to make a bigger and dirty one.

      I want to add an addendum that I personally don't lose sleep over the threat of a terrorist attack. More people die every day in car wrecks or from heart attacks than in any terrorist attack. While I eat a pretty healthy diet, I drive rush hour traffic every day and don't drive slow. My risk from that is about a thousand times worse than any sort of terrorist attack, especially if I were to figure in that I don't exactly live in a top 10 list of potential targets (or top 1000 for that matter). I just wish more people would think about the simple statistics instead of the "fear factor" and terrorists would be out of the proverbial job.

  10. Me thinks thou doth protest too much... by Lord+Kano · · Score: 5, Funny
    Hello Dante, let me introduce myself. I'm Lord Kano, and I'm about to expose you.

    Your post caught my eye because it was really funny. Then I started to wonder what else you talk about in your posts.

    Looking at your recent posting history I have found the following.

    Negroponte says Linux too 'Fat'
    • I have enough problems without slashdot starting to sound like my girlfriend.


    Startup Webaroo to put the 'Web on a Hard Drive'?
    • Would the downloadable content include porn?

      Er, I'm asking this in order to, er, protect my girlfriend's sensibilities. Can't have her unwittingly downloading such naughty stuff you know. =)


    Two Unofficial IE Patches Block Attacks
    • Are you related to my girlfriend? Because she asks smart questions like you. =)


    So many references to your "girlfriend" in so short a time aroused my suspicions so I decided to google for '"Dante Shamest" girlfriend' and guess what I found.
    THIS proof that you are a liar with no girlfriend.
    • I fooled somebody into thinking that I had a girlfriend.

      But...I don't.


    You've been using the same bullshit ruse for over a year now. It's ok if you're celibate, but it's just plain pathetic to lie about having a girlfriend.

    LK
    --
    "Hi. This is my friend, Jack Shit, and you don't know him." - Lord Kano
    1. Re:Me thinks thou doth protest too much... by jpardey · · Score: 5, Funny

      Of course there isn't a big conspiracy. A oonspiracy requires more than one person, and it is quite clear you are singular.

      --
      I have freaks! I did something right...
    2. Re:Me thinks thou doth protest too much... by Lord+Kano · · Score: 3, Interesting

      There's no big conspiracy. I just have a really annoying girlfriend.

      You made a good run of it, but the ruse is over.

      LK

      --
      "Hi. This is my friend, Jack Shit, and you don't know him." - Lord Kano
    3. Re:Me thinks thou doth protest too much... by Progman3K · · Score: 3, Funny

      I don't know what's sadder;

      Dante lying about having a girlfriend

      You taking the time and bothering to unmask him

      or me bothering to care about you nerds at all...

      --
      I don't know the meaning of the word 'don't' - J
  11. Invasion Target by Sathias · · Score: 5, Funny

    Does this mean that America is going to invade E-bay?

    --
    Blessed are the 1337, for they shall pwn the earth.
  12. benifit/cost by fermion · · Score: 4, Insightful
    Except in the case of truly irrational people, for the purpose of killing people, history tells us that the simplest tool will be used, and complexity is only introduced to minimize risk. For example, any crazy can go into a crowded place and kill several people prior to succumbing to the same fate. Likewise, a person may plant a conventional bomb and do significant damage. Certainly we have seen few cases where 'mass destruction' is caused by the use of biological agent by non-governmental foces. Even the Anthrax in the mail scare caused no more damagae than the unibomber, and that anthrax may have been top grade US governement.

    So here is the rub. One not only has to have the equipment and expertise to create the biowepon. One also needs a way to infect people in lethal doses. And, to begin with, one needs to believe the bioagent will be more effecient than conventional weapons. Look at it this way. The allies probably did more damage in Dresden using conventional weapons that in Japan using nukes. However, the Japan attack was much more effecient, posed almost no risk to the Allies, had no real defense, and was not limited by the logistics of flying many planes. For a bioagent to be preferable, it must be like a nuke. If Bush is to believed the Iraqis have a bunch of biological agents, yet we see bombs are used more. Perhpas the Iragis to have WMDs, and bombs are just so much more effecient and dramatic. I mean proving to the US forces that defending against IEDs is hopeless to so mouch more dramatic than simply killing everyone in the green zone with lead poisoning, for instance.

    This seems like another fear mongering article planted to create an impression that certain not-so-dangerous things are critical, so that the complex really dangerous things can be ignored. It just shows a true lack of imagination. I tink in most cases the villians just want the drama. That is why they blow up the building after it is evacated, instead of blowing up the location to which the people are evacuated to.

    --
    "She's a scientist and a lesbian. She's not going to let it slide." Orphan Black
  13. Nukes are a different thing entirely by Goonie · · Score: 4, Insightful
    Correction - it takes some highly enriched uranium, a library card, and an electrician to make a nuclear weapon.

    Making HEU is a very difficult task; Zippe-type centrifuges can't be put together in your back shed. More plausibly, they could steal it or buy it on the black market, but even that's going to be very difficult.

    WMD's are a bogus category, in my opinion, draw a bogus analogy between nukes, which genuinely can kill tens of thousands of people at a shot without any great operational genius, and chemical and biological weapons, which seem to be very hard to make that lethal, even though theoretically they can be.

    --

    Any sufficiently advanced technology is indistinguishable from a rigged demo
    --Andy Finkel (J. Klass?)
  14. Yeah, whatever. by khasim · · Score: 3, Informative
    As someone who is doing research in molecular biology right now in a major US
    university (at a postdoctoral level), let me assure you a lack of decent edumacation in the field of biology is not the problem.
    Yeah, sure. Whatever.
    Once this technology becomes available to 14 year olds and doable with classroom equipment, all bets are off.
    At that point all the claims you've made have already been researched and, at least in the lab, developed.

    Seriously, I'd expect someone with your claimed credentials to understand the basics of this. This isn't cut-and-paste.

    You have to identify the exact DNA/RNA sequence that identifies your target.

    Then you have to engineer the virus to only kill the hosts with that sequence ...
    while remaining dormant in the hosts without that sequence.

    And you can't just cut-and-paste the sequence you want to attack into the virus. The changes to the virus would be a completely different research project.
    And let's not forget the people who are depressed and want to see their offender dead and they don't care about the world or themselves.
    And why would that person choose bio-tech over the conventional shotgun?
    And this is before we even mention terrorists and nation states which TFA was concerned with.
    Because chemical agents work so much more effectively, are easier to manufacture, transport and disperse.

    And even more effective than chemical agents are conventional weapons. Such as "hand guns" or "shotguns". Not to mention the ever popular "explosives strapped to your body".
  15. Popov? by Ajaxamander · · Score: 3, Funny

    A soviet bioweaponeer? NOW I get why the lower-shelf vodka of same name is so toxic.

  16. Scientists and Public Responsibility by LotTS · · Score: 3, Insightful
    This is the classic dilemma regarding responsibilities with the impact on humanity from scientific advancements. Who has it now? Who should have it?

    In the classic days of Leonardo da Vinci, the Renaissance Man was the master of everything and was on top of many topics of interest. However, many modern achievements have been realized through specialists - science, engineering, agriculture, arts, etc... It would not be fair for a world-class scientist to be responsible for establishing the policy guidelines of a new technology. Their main concern is and should be to advance the frontiers of science - their opinions should carry weight regarding policy, but in general they are not adept with such responsibilities.

    In the absence of an appropriate entity with this responsibility, the lack of oversight may lead to unwanted outcomes. Einstein's revelations made the atomic bomb feasible, yet afterwards Einstein was one of the biggest opponents of nuclear arms. As someone who is in biotechnology, I know that we may have social responsibility on the back of our minds, but in the forefront is finding that discovery before someone else in our field finds it first!

  17. Bill Joy and others saw this years ago by schwag+monkey · · Score: 3, Insightful

    Bill Joy's well-known article "Why the Future Doesn't Need Us" predicted this like 6 years ago:

    http://wired-vig.wired.com/wired/archive/8.04/joy. html

    The big quesiton is: why aren't the intelligent, well-educated, technically minded of the world actually taking issues like this seriously, and doing something about it? Probably because thinking about this stuff means questioning one's own vocation and existence, and perhaps discovering that the blind pursuit of scientific knowledge or development of technology can have just as many unintended bad consequences as good ones. We can't stop these pursuits; nor should we. But all who are involved in these pursuits must also assume responsibility for analyzing the risks of their application.

    Bill Joy called for a "Hippocratic Oath" of sorts for scientists and technologists to take responsibility for the ethical concerns as well as the scientific or technological or design concerns. We already know how to assess some forms of risk. These are just different kinds of risks to be assessed, and they are real.

    If we are as good and as smart as we think we are, how can we not step up?

    1. Re:Bill Joy and others saw this years ago by Shihar · · Score: 5, Insightful

      You can't stop science.

      This isn't like a video game where you need to go down the 'horrible biological weapons' research tree in order to get horrible biological weapons. The same technology that lets you engineer a crop that can end world hunger or create new organs from scratch is the same path that leads to horrible weapons. You can't simply pick the good over the bad. By advancing forward you WILL uncover the bad and make available the tools to do terrible things. The only option you have left is to either grind to a technological standstill or simply do your best to fend off dangers as they come.

      The only way to stop technology is to put in place a world wide totalitarian government that ruthlessly enforces 'sustainable' living and the freeze of technology. By "sustainable", I don't mean the crunchy American tree hugger version that involves eating a lot of soy and riding a bike while still enjoying central heating and electricity. I mean brutal Maoist style raw utilitarianism that merrily sheds lives in favor of the higher goal of a "sustainable" society out our present technology level.

      This of course is an utter impossibility. Our system is like a shark. It moves forward or we all die. No little tweaks on society is going to make it so that we can maintain this state of technology forever. We will run out of resources and technology will either have an answer waiting or everything collapses.

      The only answer is to cross your fingers and hope to hell that a Kurzweil utopia is right around the corner. The best thing we can do now is try and build defense when it is possible and blindly sprint forward hoping to hell that somewhere along the way an answer jumps out before something terrible happens.

    2. Re:Bill Joy and others saw this years ago by Metex · · Score: 3, Interesting

      why aren't the intelligent, well-educated, technically minded of the world actually taking issues like this seriously, and doing something about it?

      I think of two reasons when asked this question:
      1) I have to spend, minimum 8+ years doing focused study in one area of knowledge just to get to the fringes of the body of knowledge in which I will be developing technology in.
      2) I have to take all of those 8 years of knowledge condense it into a catch phrase of 2-10 words which explains the problem to people not in my field.

      Part 2 is the killer. How am I going to explain a problem when I can't go 2 words without saying By X s postulate, or according to Ys theorem or Zs experiment? Also I need to make sure I take into account 1000 people using my work as reference and building upon it? The nuclear bomb wasn't made by 1 scientist in was made by thousands.

      The way intelligent, well-educated, technically minded people end up explaining things to people who make the decisions is try to find the most simplest explanation possible that maybe gets 70% of the problems across. Take 'Global Warming' sounds kind of bad and it tells you the earth is heating up. But actually we are trapping more energy in our atmosphere so a more accurate description is 'Global Energy Increase' which unfortunately sounds somewhat positive. This is a tad more accurate since instead of the earth just heating up it also takes into account places getting much colder then usual (refrigerators need energy to run). We can continually expand it until it turns into a 500 page report, but no one will remember why we are concerned about the original problem.

      Unfortunately allot of stuff can't be reduced to that level so it gets swept under the carpet.

      --
      Never could figure out why my girl liked my bitch tits, then I found out she was a lesbian.
  18. Some info not in the wikipedia blurb by patio11 · · Score: 4, Informative
    I wrote a research paper on Japanese responses to terrorism a couple of years ago. Here's what I remember from it. No warranty that any of the following is correct but, hey, do you get that warranty from Wiki?

    * The major failure with the attack was the lack of time to develop a good dispersal mechanism, as the attack plan was moved ahead of schedule because of the cult's impression that the authorities were going to act on them imminently. They had this impression on the basis of penetration of Japanese military and police sources. They eventually settled on liquid in bags getting poked with umbrella tips.
    * The "specific targets" at Matsumoto were judicial magistrates whom the cult thought had a hand in the investigation against them. Seven died in that attack, incidentally.
    * Aum was fricking scary with the amount of resources they had at their disposal. I remember a $300 million chemical weapons factory (operating completely above-board in Japan in broad daylight, just another chemical factory, had all its permits), and them staging a parachute raid on a JSDF facility using turncoat JSDF forces. Sounds like a bad anime, I know.

    I wouldn't be sanguine about this. If you can get weapons grade sarin you can certainly develop a delivery system for it. Its not trivial but, hey, $300 million dollars has a certain way of making non-trivial problems seem a whole lot less daunting. We lucked out in a major way, in that with everything designed right for the attack (high-profile target with hundreds of thousands of people in an enclosed space) the cult made multiple errors (impure toxin, dispersal surface area the size of an umbrella puncture, etc) which minimized the casualties. There were other lucky incidents, too -- two Japanese station attendants soaked up the chemical in one car with newspapers, sealed it in plastic, and took it to the station room (I don't know if they had any idea that they were dealing with anything worse than a liquid mess, but both of them died for their troubles, which many people from exposure to that portion of the attack).

    And, incidentally, remember the anthrax attack on the US and how the postal system and much of the East Coast essentially *shut down* with less casualties? Its difficult to overstate how much of the Japanese economy/government/everything is dependent on Tokyo and how dependent Tokyo is on their mass transit system. If you hit one car in Tokyo's inner loop with a lethal nerve agent tomorrow and then followed it up with a successful strike once a week for, oh, I don't know, two weeks? Three? That would be about as effective at causing economic damage in Japan as driving an airplane into a tall building of your choice in New York City.