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Scientists Find Brain Cells Linked to Choice

An anonymous reader writes "Scotsman.com is reporting that Harvard Medical researchers may have found the neurons, or brain cells, that play a role in a persons ability to choose between different items. From the article: 'Scientists have known that cells in different parts of the brain react to attributes such as color, taste or quantity. Dr Camillo Padaoa-Schioppa and John Assad, an associate professor of neurobiology, found neurons involved in assigning values that help people to make choices.'"

27 of 279 comments (clear)

  1. Does genetics make our choices? by crazyjeremy · · Score: 3, Interesting
    An interesting article indeed.

    I personally feel that there are so many "disorders" these days, that people often find a crutch for every vice and desire. Instead of working tochange for the better, people say "That's the way I am... I can't change."

    Some of these people may think this article proves that thought. I for one, feel it supports the opposite.

    From the article:

    "The monkey's choice may be based on the activity of these neurons," said Padoa-Schioppa. Earlier research involving the OFC showed that lesions in the area seem to have an association with eating disorders, compulsive gambling and unusual social behaviour. The new findings show an association between the activity of the OFC and the mental valuation process underlying choice behaviour, according to the scientists."

    I think people still have choices regardless of the addiction they suffer from (OCD disorders, Serial Killer, Gambling, etc.) A person doesn't HAVE TO Gamble, but it feels that way. He doesn't HAVE TO wash his hands 5 times, but he thinks he does.

    These abnormalities or "lesions" in our brains may make us feel we do not have a choice. In reality if we are honest with ourselves and we work hard to overcome these urges, we can overcome almost any adversity, vice or compulsion.

    1. Re:Does genetics make our choices? by the_humeister · · Score: 4, Interesting

      I guess it depends on if you believe that reductionism is true. Thus if we reduce all of our actions and decisions to physical phenomena, we're probably going to find that none of our actions are a matter of "choice." Rather, the actions we take are inevitable given the exact state that our brain is in and the exact environment we are in.

    2. Re:Does genetics make our choices? by heinousjay · · Score: 5, Insightful

      Forgive me for saying so, but it seems like you had a preordained conclusion and you're just, well, twisting the article just so to support it. Actually, saying your twisting it is overstating the case, because you're really just stating it supports your case without demonstrating how.

      If I'm wrong and you actually have some connection aside from what looks to be personal prejudice against people with disabilities, feel free to post it.

      --
      Slashdot - where whining about luck is the new way to make the world you want.
    3. Re:Does genetics make our choices? by Anonymous Coward · · Score: 3, Insightful
      I personally feel that there are so many "disorders" these days, that people often find a crutch for every vice and desire. Instead of working tochange for the better, people say "That's the way I am... I can't change.

      "Thanks to the notion of dysfunction, every zipperhead in this country can tap himself with a Freudian wand and go from failed frog to misunderstood prince."
        - Dennis Miller

      That's the thing. Being "average" has become almost a crime in Western society. But by having some sort of "disorder", being average becomes OK because "look at all you have had to overcome just to live a 'normal' life!" Also, you can get the sympathy from others - the "aaawwwwwe" factor. A LOT of folks confuse pity with "love".

      We worship the outstanding soo much, that everyone tries to become outstanding in some way - even if it means eating bull anuses on TV to become famous. I mean, why the fuck is Paris Hilton, Kato Katlin, etc... famous? These people are nothings (maybe nothing with money). At least your Joe Average-Sixpack who raise a decent family has contributed more to society than all of those people combined.

    4. Re:Does genetics make our choices? by David_Shultz · · Score: 4, Insightful
      I personally feel that there are so many "disorders" these days, that people often find a crutch for every vice and desire. Instead of working tochange for the better, people say "That's the way I am... I can't change."
      I think people still have choices regardless of the addiction they suffer from (OCD disorders, Serial Killer, Gambling, etc.) A person doesn't HAVE TO Gamble, but it feels that way. He doesn't HAVE TO wash his hands 5 times, but he thinks he does.

      Likewise, gravity doesn't force us to fall, it just feels that way.

      Seriously dude, there is a reason the above mentioned disorders are classified as as such -because something is wrong (ie out of order; or if you prefer disordered) with the workings of the brain. For you to just jump up and say, "you know, I think these people really do have a choice." Is not just enlightened (nor does it follow from the article in any coherent way) but it is also insensitive and maybe even mean -it serves only to shift responsibility to people who should rightly be considered victims.

    5. Re:Does genetics make our choices? by crazyjeremy · · Score: 3, Insightful
      I a mild OCD and Chronic Daily Headaches http://www.achenet.org/kids/chronic.php

      Every day of my life I want to fall back on these things as an excuse of why not to try to hard, to just take it easy. But I know if I do that, things always just get worse. Imagine having a headache EVERY day of your life and wanting to live one adrenaline rush to another to ease the pain. It destroys your life...

      When I treat compulsions as choices, I become more able to fight them. The article just made me feel like had a choice, even if one of the choices was not as easy... I guess people could take it however they want, though.

    6. Re:Does genetics make our choices? by Rakshasa+Taisab · · Score: 3, Insightful

      The fallancy here is that the word "choice" hasn't been defined sufficiently. Your post gives me the impression that you are assuming that to make a "choice" cannot be a physical phenomena. This will force those who believe in reductionism to come to a, possibly incorrect, conclusion that none of our actions are a matter of "choice".

      I think would be possible to find a good definition of "choice" which does not assuming it must be a non-physical phenomena, a definition that would be much more useful.

      --
      - These characters were randomly selected.
    7. Re:Does genetics make our choices? by suv4x4 · · Score: 3, Insightful

      Thus if we reduce all of our actions and decisions to physical phenomena, we're probably going to find that none of our actions are a matter of "choice."

      I can't believe modern people have a difficulty grasping this.

      How the heck our ability to make "choice" is prevented by it being dictated by the state of our own brain. Apparently most people contribute "choice" to our "ghost/soul" and thus the moment they find that (shocking) we're thinking with our brain, they automatically assume that our brain dictates to our soul what choices to make (therefore "we can't make anything on our own, we can't change, we're not responsible" and other nonsense).

      Shocking news people - you ARE that brain. And other shocking news, you see with your eyes, you hear with your ears and smell with your nose. You are what your body is, and your body can make its own free choices which are predisposed by the state it's in.

      If we couldn't base our choices on our body/brain state, then we'd simply have no information or mechanism to make any choices whatsoever.

    8. Re:Does genetics make our choices? by the_humeister · · Score: 4, Informative
      Wikipedia has a nice write up about this. In the Common Pitfalls section it states:
      It is worth noting that the halting problem is decidable for deterministic machines with finite memory. A machine with finite memory has a finite number of states, and thus any deterministic program on it must eventually either halt or repeat a previous state. Repetition of a previous state indicates a loop, so a program that repeats a previous state is thus known to not halt.
      That implies that anything finite has a decidable outcome.
    9. Re:Does genetics make our choices? by onemorechip · · Score: 3, Insightful

      Mere uncertainty or chaos doesn't imply choice. Nobody knows exactly how many stars are in the Milky Way (uncertainty) or whether the stock market will be up or down tomorrow, but that doesn't mean we have any choice in those matters.

      In any matter of choice, what is it that is doing the choosing? Choices may well be "mere" physical phenomena, but can we identify with that physical state, or not?

      When asked if I believe in free will, my response is, "Free from what?"

      --
      But, I wanted socialized health insurance!
  2. First thing we do... by darkitecture · · Score: 4, Funny

    First thing we do, we find out which cell is responsible for making guys choose to wear pink shirts.

    Every guy who has an active pink-shirt cell then gets neutered (or would they technically requiring spaying?).

    1. Re:First thing we do... by pHatidic · · Score: 4, Funny

      Yeah, I agree. It's not like they will be able to propagate anyways.

      Wearing pink for a guy shows self-confidence, the trait most attractive to women. If you are able to wear a pink shirt and no one gives you shit about it, it shows that you are a dominant male. It is a great way to show value to women. It's completely true, I read it in a magazine once. I think it was in PC Gamer.

  3. Brain involved in choice by truckaxle · · Score: 3, Funny

    brain cells linked to choice Wow and I always thought it was the lung cells that determine choice.

  4. Have they found the stupid part yet? by Timesprout · · Score: 3, Funny

    Let me know when they find the part that makes stupid choices for me so I can have it removed

    --
    Do not try to read the dupe, thats impossible. Instead, only try to realize the truth
    What truth?
    There is no dupe
  5. Ahh, free will by brian0918 · · Score: 4, Interesting

    It's time for the age-old debate about man's free will. Does it exist, or are we just kidding ourselves? Is the consciousness an intact "entity" within the brain, or is it simply the end result of external stimuli influencing choices? One thing is for sure: neuroscience is making it more difficult for a spirit to hide in our mushy insides. Eventually, we'll know for sure how the brain works. For now, we are stuck with debating the definitions of words like soul, freedom, consciousness, etc...

    1. Re:Ahh, free will by mrchaotica · · Score: 3, Funny
      Does it exist, or are we just kidding ourselves?
      If it doesn't then we have no choice but to kid ourselves, now do we?
      --

      "[Regarding the 'cloud,'] ownership was what made America different than Russia." -- Woz

  6. I do not understand by thePig · · Score: 3, Interesting

    Shouldnt memory play a role in this?
    I was under the impression that memory (basically hippocampus and amygdala) was the reason we chose items.
    For example -
    Grape - Appropriate synapses of the looks of the grape colour,look etc all get burned up in hippocampus
    Also, when we eat it - the synapses for amygdala set for pleasure also gets set up.
    Also a combination path way neuron for both also gets hardened due to electrons going there - (in hippocampus).
    Now next time I see a grape, this compination path gets a signal when we see a grape - so a signal goes to the other one (for pleasure also), thus the memory of pleasurable experience when a grape is eaten comes to me.
    This is memory.

    Now, for a choice, depending on the amount of pleasure, my synapses fire more and I go for that.
    For example - if there is bittergourd and grape, I will go for grape only.
    I thought the monkeys choice depended on these neurons rather than the one they speak about.

    Or is this the intelligent choice they are talking about - where in I go for bittergourd instead due to the higeher nutrition content ??? .. I thought that also could be expressed in the earlier way mentioned.

    --
    rajmohan_h@yahoo.com
  7. What about personal responsibility? by gansch · · Score: 3, Insightful

    It seems to me that, for the average person, this would play a small part in actually making choices...most incorrect choices tend to be made due to incomplete information, selfishness (including refusing to hear others opinions or accept advice), or denial of what is known or true.

    Sure, these neurons may be involved in the process of making judgements, but if the person does not understand or refuses to accept the choice, he is setting himself up for failure before the brain even gets to this step.

    I agree with some of the other posters that this discovery may be misused as an excuse for poor choices and behaviors that the individual has an inkling may be incorrect. But, I hope we come to our senses and start taking personal responsibility for our lives, instead of making biological and societal excuses for everything that "goes wrong".

  8. Free will, souls, adn the brain by plunge · · Score: 4, Interesting

    There have been many fascinating finds in this field over just the last couple of years, from the discovery that you can externally trigger feelings of volition to be associated with artificially stimulated actions (i.e. make you feel like you CHOSE to move your arm, when in fact it was the scientists stimulating your nerves), to the discovery that religious ecstasy can be likewise triggered.

    In all of this, I've always been confused by those that suggest that human consciousness is better explained by a soul or free will. As far as I can tell, neither "Free Will" nor "soul" actually explain ANYTHING about conscious volition. Certainly, conscious experience is a philosophical mystery: what is it, and why is it? Nobody knows. But simply referencing some random word like "soul" and noting that it is supernatural doesn't explain anything. It's not that the rules of the natural world are too restrictive to allow "free will" or "conscious experience" to work. It's that we have no idea what they are or how they work at all. So positing some supernatural realm where anything is possible doesn't help, or advance our knowledge even a bit.

    Free will is actually even more bizarre, because although many people claim we have it, no one seems able to actually define what it is or what difference having free will vs. not having it would make. In short, it appears that the concept is completely incoherent and self-contradictory. It's one thing to be free to make choices for yourself, according to your own volition. But that's not what the strong "Free Will" concept is: even computers can make choices for themselves. Strong Free Will posits that people somehow make choices independently of.... well what? Independently of their own natures? That makes no sense! If there isn't some underlying deterministic substrate to my choices, how can they be mine at all? How can I be responsible if you can't causally track my choices back to some "me."

    In short, "Free Will" makes no sense as a concept, and offers no explanatory value for anything. It's SOLE purpose seems to be in theological arguments, a bit of handwaving to avoid having a designer be responsible for the nature of his own designs.

  9. Continuum. by khasim · · Score: 5, Interesting
    Thus if we reduce all of our actions and decisions to physical phenomena, we're probably going to find that none of our actions are a matter of "choice."
    At the far extreme of disfunction, I think that that might be valid. It isn't easy to believe that someone chooses to be schizophrenic.
    Rather, the actions we take are inevitable given the exact state that our brain is in and the exact environment we are in.
    And that's the key.

    If this is valid, then the animals with the same neurological structure would make the same choices, right?

    So far, all that's been shown is that damaging an area of the brain results in failures to react to certain distinguishing features.

    Do monkeys with brain pattern X always choose apple juice? But monkeys with brain pattern Y always choose grape juice? And monkeys with brain pattern Z always choose orange juice?

    The same with choosing to gamble. Why does someone choose ponies over blackjack?
  10. Biology and the Human Spirit by caudron · · Score: 3, Insightful

    Reading some of the /. comments on this story, I have to say that it's always interesting to see religious men trying too hard to associate Man with the divine as though we stand above and seperate from the natural world, but equally it's interesting to watch atheists try to find mankind wholly within nature as well. For as much as we want to call Man an animal (subject to an animal's exigencies and vicissitudes) we must admit that he is a curious sort of animal able to escape those forms of nature and create new configurations of need and choice.

    I don't really have a point. I just find the whole matter of human will and spirit interesting.

    Tom Caudron
    http://tom.digitalelite.com/

    --
    -Tom
  11. Are these the same monkeys that like Fritos? by tlynch001 · · Score: 3, Funny

    Are these the same monkeys that like Fritos?

  12. Comment removed by account_deleted · · Score: 5, Insightful

    Comment removed based on user account deletion

  13. Comment removed by account_deleted · · Score: 3, Funny

    Comment removed based on user account deletion

  14. So you think you aren't free? by wytcld · · Score: 4, Interesting

    If you honestly believe you're not free, there are a number of things you might as well stop doing:

    1. Why do you consciously try to deliberate over any choices? If you are not free, that effort you're putting forth - to the extent, you know, that you have decided to try to deliberate, is at best an epiphenomenal waste. So why not save the effort? On the one hand, that epiphenomenal sense of your own agency can't really do anything in the physical world, right? On the other, for the epiphenomenal to exist it must be draining energy from the actually useful parts of the brain, which might be able to run their deterministic algorithm better if you weren't shunting that energy into the appearance of phenomenal consciousness, with its illusion of free agency and all that. So why not just give it up?

    2. The next time you blame your girlfriend or boyfriend or boss for anything, why bother? After all, they have no freedom in what they do. It was all determined from the beginning of time (if not before). So why not just give it up?

    3. When others of us say that we believe - no, we know that we are free agents, in ways that are beyond Newtonian causal physics (although not beyond some interpretations of quantum theory, e.g. Henry Stapp's or Roger Penrose's), it is absolutely determined that we will be saying these things. You could not possibly persuade us to freely change our minds through conscious deliberation on these questions. So why not just give it up?

    What these experiments may show is that the weights of particular desires are represented in particular cells in particular regions. Did you think, for instance, that thirst wouldn't be represented somewhere in the brain? What they don't (and probably can't) show is that it is merely a certain "weight" of thirst, balanced against certain "weights" of other desires, that results in action in some deterministic way. Think of it like a dashboard. There's a certain "weight" of the gas running low, a certain "weight" of the speed you're going, a certain "weight" of the oil light coming on, and even the "weight" of how many miles are on the vehicle. None of these prevent your free operation of the wheel and pedals (until the gas runs out, or a cop stops you, or the engine blows a rod, or the transmission falls on the road). Why should a dashboard in the mind representing how thirsty you are, how horny you are, how clever you think you are with your doubting of the common sense about our freedom ... why should the mere presense of any of these representations in physical instantiation imply any diminishment of your capacity to will? I'd rather say the more representations on the dashboard, the more the driver is freely in control.

    --
    "with their freedom lost all virtue lose" - Milton
    1. Re:So you think you aren't free? by munrom · · Score: 3, Informative
      1. Why do you consciously try to deliberate over any choices?
      Because you don't have any choice in the matter? If all our decision are determined by brain makeup then the choice to consciously deliberate over a choice is not actually a choice.
      2. The next time you blame your girlfriend or boyfriend or boss for anything, why bother?
      Again, you don't have a choice. You are acting this way because the makeup of your brain says that's what you do in that situation.
      3. ...You could not possibly persuade us to freely change our minds through conscious deliberation on these questions. So why not just give it up?
      But the catch is the person trying to convince you you're not free is not free to choose. Personally I believe a person placed in the exact same scenario will do the exact same thing every time, the problem is there is no real way to test it because as soon as it's been done once the senario is not the same as the brain has extra information it didn't have the first time.
  15. Libet by wytcld · · Score: 4, Informative

    According to some research consciousness is something that comes *after* the rest of your brain already made the choice. So you can't do anything consciously to begin with.

    You're talking about Libet's well-known research, and mischaracterizing it. In his experiment people have already decided to move their arm, in cooperation with the researcher's request, at a "random" time. They're also watching a clock on a computer screen, and are to push a button at the time that they are aware of making the choice to move their arm. Meanwhile Libet is monitoring what he interprets as a "readiness potential" at a certain location in the brain, which is a good predictor of moving your arm. The finding is that the potential is there before the subject reports awareness of the volition relative to the clock. However, Libet also found that people can successfully decide not to move their arms even after the readiness potential was in evidence. These findings are still much debated. But what they do not show is anything about the efficacy of complex, conscious deliberations.

    without defining "free" there is no way to talk about it in a meaningfull way

    You're working from an old, bogus notion in philosophy that we must "define our terms" before we can talk about anything. It's a failed program. Terms don't get meaning that way. Rather, terms get meaning from context, and from overlay ("blending" is the technical term in modern cognitive linguistics) with other contexts. There are few if any things that we can define (1) without context, and (2) without being in some sense circular. Yet there are a great many things we can talk about in a meaningful way - although it depends who we're talking to. Still, most all of us know, from our contexts in life, what freedom is, and what it is to will something to happen. That you can befuddle yourself about what these words mean is nice; but we can befuddle ourselves about any word if we just repeat it to ourselves a few hundred times. And that's basically the whole trick about demanding a definition before allowing a discussion to proceed - with every repeated demand you're moving the word closer to that temporarily alienated state. But, since that can be done with any word, what you've done is just on the level of a psychological illusion, not a revelation of the ill-defined meaninglessness of whatever word you've targeted.

    --
    "with their freedom lost all virtue lose" - Milton