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Deep Brain Stimulation as Depression Treatment

Neopallium writes "Medtronic, today announced its intentions to pursue a major clinical trial of the company's deep brain stimulation (DBS) technology in the treatment of severe and intractable depression, a disabling form of the psychiatric disorder affecting millions of people worldwide. "While not a cure, DBS has allowed these patients to return to much more functional and happy lives," said Dr. Rezai, who represented an international working group of physicians that has been studying the application of DBS therapy in the treatment of intractable depression and OCD in collaboration with Medtronic."

4 of 273 comments (clear)

  1. Unexpected side-effects by tomhudson · · Score: 4, Insightful

    This could have some rather unexpected negative side-effects. For example, Lincoln was prone to depression - if he had been less melancholic, perhaps he wouldn't have spent so much time brooding over the negative consequences of slavery to the union. Similarly, this could spell the end to a lot of literature ...

    How depressing ...

    1. Re:Unexpected side-effects by BiggerIsBetter · · Score: 4, Insightful

      I just hope no one in the trials commits suicide, a common occurrance of people who are just beginning to have their depression lifted.

      That's an interesting turn of events. You feel too depressed to do anything, then you start to come out of it. You still feel really down, but have the motivation to not want to feel like that anymore... yet can't imagine a lasting brighter future without coming back down again.

      So what's the obvious solution when you don't want to live that way, and don't believe you have an alternative? You make a choice to stop living. It seems very reasonable at the time (been close a few times myself).

      --
      Forget thrust, drag, lift and weight. Airplanes fly because of money.
    2. Re:Unexpected side-effects by Ohreally_factor · · Score: 4, Insightful

      Sure, there *are* rambling homeless people, depressed people and confused people out there, but hasn't this always been the case? Or is the general consensus that it happens more often now and needs treatment?

      Your ignorance about the suffering of the mentally ill is quite charming. You might as well as, "Why don't the clinically depressed just cheer up?" Someone undergoing a major and debilitating depression isn't "a bit off" nor are they merely eccentric oddballs.

      I'm sorry if this is a bit harsh; I believe you are sincere and that your questions, as you say, are honest. However, if you are honestly curious about mental illness, you might want to get a college textbook on abnormal psychology and read up on it. You are not going to get much light shone on your ignorance in the comments section of slashdot.

      --
      It's not offtopic, dumbass. It's orthogonal.
    3. Re:Unexpected side-effects by wazzzup · · Score: 5, Insightful

      It's not about fitting in or creating a socially acceptable human being through chemistry. It's about relief from the prison of your mind.

      As someone that suffers from bouts of major depression and obsessive-compulsive disorder (OCD), if the treatment leaves me in a state of being "a bit off" but in a state where I can function in day-to-day society - that's okay.

      Without treatment, I'm prone to lie in bed all day barely able to speak (the depression) while my mind (figureatively) straps me in front of an IMAX screen and makes me visualize horrible things like blowing my brains out over and over again, throwing my son off a cliff, being gang-raped and other lovely sunny-day thoughts (the O in OCD). Obsessive thoughts are completely unwanted (they don't indicate some subconcious desire) thus feeding the depression which, in turn, makes it harder to block the obsessive thoughts. In my case, I wasn't hurting others (except my family who had to watch me go through those episodes) but I was hurting myself.

      While I don't think we should strive for a Stepford Wives kind of norm through medication, the medication is a godsend - not an Orwellian mind-control tactic. While you or someone else may think "so they're odd - leave them alone, it's who they are" it's *not* who they are. Who they are has been dominated and replaced by the condition/disease. I completely understand why someone that has not experienced mental illness might see things in the manner you describe. In fact, most people with mental illness won't tell thier friends or peers about thier condition because of the social stigma that mental illness carries.

      With treatment, sure there are days I'm "a bit off" but that's okay - no one's the wiser.

      I guess what I'm trying to say is that, while "oddballs and eccentrics" might not be hurting anyone, they may, in fact, be hurting intensely within - wishing they could rid themselves of the oddness and eccentricity and become the person they really are. The oddness is just a small part of what surfaces to the outside world. That's not to say that all oddballs and eccentrics are mentally ill either and that's truly just who they are.

      In regards to wondering whether these conditions are more prevalent than they were in the past - yes, based upon my personal research on the topic.

      I hope my personal experience may have answered some of your questions.