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Photonic Breakthrough Allows 'Lab-on-a-Chip'

Roland Piquepaille writes "Georgia Tech researchers have shrunk an optical device called wavelength demultiplier (WD) by combining into one crystal three unique properties of photonics crystals. This optical discovery opens the way to sophisticated and cheap bio-sensors mounted on 'lab-on-a-chip' devices -- sensors to run blood tests, detect chemicals in water supplies or for drug testing. Their new WD is less than a millimeter in all dimensions rather than the several centimeters of other currently available WDs. And it should not cost more to produce."

19 of 72 comments (clear)

  1. Let me get this straight. by gpn · · Score: 5, Funny

    40 WDs = 40 x WD = WD40 ?

  2. WD for computing by gigne · · Score: 3, Insightful
    Interesting...

    Now the key components for processing light have been miniturised, it should be possible to use this for the basis of a simple optical computer.
    From the sources below:

    http://www.theregister.co.uk/2006/08/03/photonic_c rystals/
    The design also eliminates problems of wavelength interference, which means that although the crystal is tiny, it will work at very high resolutions - between 64 and 100 microns.

    So... it seems like the photonics are ready. We just need engineers to step up to the challenge.
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  3. Fear mongering scapegoats ahoy! by lisaparratt · · Score: 3, Insightful

    drug testing

    The War On Drugs is sooo last century - didn't they get the memo that we're fighting the War On Terror now? They haven't sensationalised it enough - they've got chemical attacks on water supplies in there, but it's too subtle - where's expolsives detection at customs on their list?

    1. Re:Fear mongering scapegoats ahoy! by Silver+Sloth · · Score: 4, Insightful

      Maybe I'm dumb, but I read it as 'testing drugs' - monitoring the changes in the body when certain drugs are used. As someone who is (remotely) involved in Medical Research I feel this is a Good Thing (TM).

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    2. Re:Fear mongering scapegoats ahoy! by andrewman327 · · Score: 2, Insightful
      Just wait until TFA makes it to the nightly news. It is the media, after all, that adds all of the spin.


      And tonight on NBC10 News at 11, a new discovery that will make it easier to protect the nation's water supplies from terrorist attack. You see, our water supplies are at risk. All a terrorist has to do is come here, 3 miles NW of I-95 exit 37, and add between 1 and 2 quarts of chemicals to this reservoir to endanger millions in the Philadelphia area. They had better do it soon, however, as this new 'Lab on a chip' will be able to detect such quantities when it comes online in 11 months."

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  4. propagating typos by geeber · · Score: 3, Informative

    That's a "wavelength demultiplexer". It is wrong in the original article.

  5. Demultiplexer not demultiplier by coinreturn · · Score: 5, Informative

    The error is in both the article summary and one place in the article. The proper term is "demultiplexer," not "demultiplier." A "demultiplier" is called a "divider."

  6. "Allows"? it's already possible by pimpimpim · · Score: 5, Insightful
    There's a whole journal devoted to lab on a chip, bringing this small part of the technique as the only thing needed to make labs on a chip (lab on a chips?) is a bit of an overstatement

    As a scientist, this is what I don't really like about scientific journalism. Like the 'New breakthrough in fighting cancer' titles, etc. etc. These are laboratory research developments and will take at least 10 years to evaluate, some of them will end up being impractical before ever being put to use.

    I think that scientific journalism should be more than just a PR machine for research labs. Of course they want the message out that they're doing nice stuff, but as it are all just small pieces of advancement, don't bring it as if you just developed a working nuclear fusion reactor ready to connect to the powergrid. Show that you're doing someting nice, what it can do, what the scientific/technical genial idea is that was done to get it, and in what frame we should see it, that should be enough.

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    1. Re:"Allows"? it's already possible by amide_one · · Score: 4, Interesting

      Only trouble with that is that scientific journalism isn't aimed at scientists; it's aimed at the generally-educated layman, who outnumber scientists hundreds to one. And so the average reader isn't going to be very impressed by "this new device could allow the integration of another optical component onto the chip rather than the reader, reducing the cost of the reader and the risk of carryover" -- or at least, he'll find "will allow 'lab on a chip' devices" a lot more impressive. There's already plenty of literature aimed at scientists.

      Scientific journalism really *is* PR; the reason universities and "Scientific American"-type magazines publish these things is to show people what science is doing lately... and why you should encourage your kids to grow up to be scientists, why you should write to your Congressman to support the NIH, why you should make a generous bequest to your alma mater, etc.

      That said, it really isn't correct to report an incremental advance as more than that. (And not even one actually ready yet for micro-TAS systems; they demonstrate a device optimized for 24 channels over 1.5-1.6 um.) Not to say that it's not an impressive bit of work.

    2. Re:"Allows"? it's already possible by amide_one · · Score: 2, Informative

      Every single school, from the community college on up, is going to do everything it can to convince its alumni, students, faculty, and benefactors that it's doing useful and important work. Even "MIT, CMU, Stanford, etc." issue the exact same kind of PR. It's necessary everywhere.

      The Bad Thing is confusing the explanation in the PR with the real research or discovery, or assuming that it's actually important because the school PR office thought it sounded neat. Which is how Roland Piquepaille wound up propagating the PR writer's mistake on the terminology ("demultiplier").

    3. Re:"Allows"? it's already possible by amide_one · · Score: 2, Interesting

      Of course they're looking for more grant funding. Everyone is, always. :)

      At least at my school (and apparently at Georgia Tech as well), there's a separate "news office" that does the reports like this -- an internal "journalist" (or half reporter, half PR person) comes to the lab and interviews the professor when they get wind of something impressive/marketable. They write the article, based on background and specifics given by the professor. They distribute it, via the university's website and alumni magazine and possibly the student newspaper (if it's big enough).

      That's why the "article" is credited to "Institute Communications & Public Affairs" rather than the individual lab, and why the "article" describes it as a "wavelength demultiplier". If the academics had prepared it, or even had approval on the final copy, they surely would've caught the mistake. (The question of why such "reputable" science bloggers as Roland Piquepaille didn't catch it is easily answered -- paraphrasing the PR is easier than condensing the actual article.)

  7. Coming next week... by Richard_at_work · · Score: 5, Funny

    Poodle-on-a-chip, jackrussell-on-a-chip and the all time favourite alsation-on-a-chip.

  8. Wavelength-accurate cameras by Anonymous Coward · · Score: 5, Interesting

    Makes me wonder about using an array of them in a camera in order to record colour images in terms of their actual spectral content instead of approximating down to red, green and blue. Then just run them in reverse (I assume the optical demux can be used in reverse) to re-create the display.

    This would make a convincing display even for those with colour blindness or http://en.wikipedia.org/wiki/Tetrachromattetrachro matic vision.

    As an aside, it has been mentioned that humans with tetrachromatic vision can see through various types of man-made textiles ;-)

    Sadly, human tetrachromatic vision occurs only in females :-(

    1. Re:Wavelength-accurate cameras by hcob$ · · Score: 2, Interesting

      IIRMECC (if I remember my electronics class correctly). Muxes and DeMuxes are complimentaries of the other, but they cannot be "used in reverse". This my not apply to optics, but I'd wager that they wouldn't use the logical circuit naming if it wasn a near parallel in operation.

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  9. LabManPower by Doc+Ruby · · Score: 3, Interesting

    Great! So now I should be able to get a little lab on a chip that analyzes the air and water around me, wherever I go, for pollutants and toxins. Am I glad that we've got the Clean Air Act and Clean Water Act that keep my personal environment clean.

    Wait, my old chips are telling me that those "clean" Acts are really "dirty". And since the police will arrest you when you photograph them, it's going to be tough on people getting the dirt on polluters.

    Or maybe these little LabMans on every allergic person's mobile phones will force a change on all that. Will the government be able to lie to us about our pollution laws being "Clean" laws when our phones are chirping whenever we leave our oxygen tents?

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  10. Healthcare + cheap, lol by Dan+East · · Score: 2, Interesting

    I'm sorry, but anytime I see some new invention (bet it instrumentation, drugs, etc) related to healthcare, and they talk about how cheap it will be, I can't help but thing "yeah, right". Maybe it's cheap to produce, but by the time this patent is grabbed up by a money grubbing corporation, then endures the expensive and drawn out FDA approval process, and finally the owner determines the maximum that Medicaid and other insurers are willing to pay for the test, it will hardly be cheap. By cheap they really mean "greater profit margin than with existing technologies".

    Dan East

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  11. Possible ideas? by DeadCatX2 · · Score: 2, Interesting

    Put some small, fast phototransistors into silicon. Use glass tubes (glass = Si) to propagate the signal to the next point, free of capacitance; maybe we can even tune the permittivity of the glass so the light can propagate faster. Build these crystals and tie them into the silicon to sense the signal and turn it back into a logic level.

    Ideal for long hauls where the capacitance is a major factor in the switching speed, or clock distribution trees. The lowered capacitance, and possible increased permittivity, would definitely lead to less skew as well.

    All assuming that this technology can switch sufficiently fast.

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  12. Very little that's new here by PhysicsPhil · · Score: 2, Informative

    The only thing that is interesting about this article is the fact that they've done it with photonic crystal waveguides. My own lab the same thing with silicon-on-insulator waveguides (not photonic crystals though). We are currently testing various biosensors, including a high-resolution (2 Angstrom target) spectrometer for interogating atomic spectra. On of our other designs has been shown to measure sugar concentrations in water, and we're moving to detecting actual biomolecules over the next few weeks.

    These guys have great PR but, like most scientific advances, the improvement is really only a tiny step.

  13. Re:What is it about the "news" from Roland Piquepa by earthsound · · Score: 2, Informative

    For an interesting and informative article on the process, see PHOTONIC CRYSTALS: Demultiplexers harness photonic-crystal dispersion properties in Laser Focus World.