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Scientists Find New Painkiller From Saliva

dptalia writes "Scientists have found a new pain killer based on human saliva. Apparently 1 gram of the new drug provides as much pain blocking as 3 grams of morphine. The drug blocks the breakdown of the body's natural pain killing mechanism. Scientists say the molecule is simple and synthesis is expected to be simple."

6 of 398 comments (clear)

  1. Re:Indeed by Ginger+Unicorn · · Score: 5, Insightful

    i think its not so black and white. if you were about to die of cancer and some scientists said they could synthesise a cure by torturing a cage full of rabbits would you want them to? Even though its a horrible choice i cant see that i would choose to die.

    on the other hand, testing something so trivial as make up on an animal doesnt have any ethical justification that i can discern. then there's the sliding scale in between.

    --
    (1.21 gigawatts) / (88 miles per hour) = 30 757 874 newtons
  2. Re:Indeed by indifferent+children · · Score: 5, Insightful
    such horror and cruelty

    I have a friend who is a neuro-oncology researcher. A very large part of her job is: causing cancer in rats, killing those rats, and sectioning their brains. Horror may be in the eye of the beholder, but she does not practice cruelty. The rats are killed by being placed into a box with CO2 (from a dry-ice chamber). That's probably a more peaceful death than I can expect.

    Granted, when you are researching pain meds, there's probably going to be pain involved. But that doesn't mean than the researchers get any pleasure out of causing this pain, or that they cause any more pain than necessary.

    If you truly feel that a rat life is worth as much as a human life, or that an hour of rat pain is as bad as an hour of human pain, then it is hard to justify your continued existence. Even if you are as green as you can get, and a hard-core vegan, your ecological footprint is very large (certainly compared to a rat), and responsible for the deaths of many small animals. The fact that you use a computer means that your carbon footprint is not that of a primitive hunter-gatherer. If you eat vegetables and/or grains, you are responsible for the deaths of several small mammals (such as fieldmice) and thousands of insects every week, just from the mechanical harvesting process (even assuming that your food is 'organic' and thus pesticide-free.

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    Censorship is telling a man he can't have a steak just because a baby can't chew it. --Mark Twain
  3. Re:Make it stop! by Anonymous Coward · · Score: 5, Insightful

    Funny, but morphine is hardly for ankle twisting pain.

    I've been on several pain management clinics/programs - the last one being pretty much on the cutting edge of medical stuff (lots of experts trained in new stuff who travel worldwide for conferences about pain management and all). I've been taking morphine several times a day for a few years for chronic pain. It sucks. The side effects suck. But it's the only thing that's given me anything close to a "quality of life".

    If it helps to put things in perspective, in the last group (about 20 ppl), when asked if we had honestly thought about ending our lives to make the pain stop, nobody's answered no. Being in excruciating pain each and every second of your life is very hard. You don't get a break when you can't handle it anymore. It's almost like being tortured, and it never ever stops, until the day you die.

    It's a very hard thing to live. Hard to get or keep a job too, when almost half the time you're either in too much pain to be useful for anything or taken too much morphine that you're not "all there" anymore. You can't drive when you're taking the stuff either. Half the docs out there see you as an addict or something. And there's the complications and side effects. And when things happen like you catch a cold or gastro and you vomit, then you can't keep down your morphine either, then things start to go REALLY bad. You gotta to to the hospital, and it's not like they'll just give you a shot no questions asked. Your self-esteem is at an all-time low (no work, feeling worthless and a burden, etc). You can't sleep right. It sucks. Your life sucks. If I didn't have kids to look after, I'd likely have committed suicide a couple years ago just to end the pain.

    Any new pain management method is a godsend. If I could, I'd volunteer to test this stuff for free (worst case scenario, I die, and the pain ends with it).

    That's the daily reality of someone dealing with chronic pain. Morphine isn't just something for addicts and getting high. It makes the lives of millions bearable and worth living. And it's not just for old folks with cancer either - I just turned 30 last month.

  4. Re:YES! by Gordonjcp · · Score: 5, Insightful

    I suggest we genetically engineer crocodiles to have warm blood and fur. That'd show them!

    That would be a cat, then.

  5. Re:No, really, an important point by wobblie · · Score: 5, Insightful

    THC has little to no addictive qualities. It is perverse how something one could grow in ones backyard, for free, is of the highest criminality, yet somehow we feel a need to come up with something else - usually not as good - that requires an entire industrial infrastructure. While it is not hard to understand the reasons for this sad state of affairs, it is still ... sad.

  6. Re:Indeed by Glyphn · · Score: 5, Insightful
    The rats are killed by being placed into a box with CO2 (from a dry-ice chamber). That's probably a more peaceful death than I can expect.

    Aside: I'm not against animal research, but as a former animal researcher who euthanized rodents I have to say that this is a rotten way to kill animals. CO2 euthanasia is not quick, the animals are clearly in distress (they die gasping for air, clawing at the container edges, rolling in their urine and feces). I can only imagine that CO2 has become popular because it sounds nice--you know, you put the animals to sleep with some gas that they breath all the time anyway.

    Better by far is cervical dislocation--a quick snap of the neck and the animal falls senseless. Unfortunately, that practice is increasingly viewed as barbaric and is discouraged in many places. It's a strange world we live in where we care less about the actual suffering of the animal than how humane we appear to be.