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Cheap, Safe, Patentless Cancer Drug Discovered

PyroMosh writes "The New Scientist is reporting that researchers working at the University of Alberta in Edmonton, Canada have discovered that an existing drug called dichloroacetate (DCA) is effective in killing cancer cells, while leaving the host's healthy cells unharmed. DCA has already been used for years to treat metabolic disorders, and is known to be fairly safe. Sounds like great news, is it too good to be true? Why is the mainstream news media failing to report on this potential breakthrough? The University of Alberta and the Alberta Cancer Board have set up a site with more info, where you can also donate to support future clinical trials."

17 of 576 comments (clear)

  1. Re:Patentless by KillerCow · · Score: 4, Insightful

    Patentless is the best part. Now, capitalism will lower the price and make it more affordable to those who need it.
    Actually, no-one can afford to run it through clinical trials since they can't protect their investment.

    It's only hope is to be prescribed as an "off-label" treatment, or for a University to foot the bill for the betterment of mankind.
  2. Re:Even this announcement is a little late... by Speed+Pour · · Score: 4, Insightful

    And the reason it won't get any funding to study whether or not it's a real cure for cancer is because there's no money in it! If it's a cheap solution and it magically cures cancer... where's the profit in that? This may not be entirely accurate. If the drug already exists, companies can mass-produce it cheaply because they also don't have to pay somebody else who owns the patent. That handles the profitability side, at least as to why companies might use it if it's ever shown to be truly successful.

    As to funding studies, there are plenty of rich people, or simply the giving types, that would donate towards this. Again, with the drug already in existence, it's not a question of production, simply a question of supply and testing expenses. I've heard the same argument about Linux (why use it? It'll never be updated because there's no money in it...) but it keeps a lot of people pretty happy. Besides, this is a college, they can apply for more grants or funding than anybody would care to count.

    The part I'm worried about...while pharmacological companies can mass-produce cheaply and without patent overhead, the bigger concern is that this drug shows some shred of a chance to cure some types/cases of cancer. The problem is, as the old saying goes "There's more money in treating the disease than there is in curing it". Just because there's profit to be made, and real potential here, there's a real chance that it won't happen because it won't induce continual and regular profit.
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  3. Re:Patentless? by Cocoshimmy · · Score: 5, Insightful

    I think what you're refering to is Socialized medicine. One of the benefits of it is the fact that the hospitals and doctors aren't out there to squeeze every last penny out of you.

  4. Re:Patentless? by littlerubberfeet · · Score: 5, Insightful

    The doctors don't squeeze. Investors/shareholders (through HMOs and for-profit healthcare companies) squeeze.

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  5. Re:Even this announcement is a little late... by Cocoshimmy · · Score: 5, Insightful

    You mention that it won't get funding because there is no money in a patentless cure. I beg to differ. At least from a Canadian perspective, where we have socialized medicine, it makes a lot of sense. This is after all a Canadian institution that discovered this.

    Cancer is very costly disease which costs the government, and as a result Canadian citizens a lot of money. If there was something that could cure cancer at a very minimal cost, it could save the government millions (possibly billions) in health care dollars every year. Not only that, many other countries which also have socialized medicine, such as all of the EU, would benefit from something like this in a similar way. I can see government funding filling the role that pharmeceutical companies normally play in this simply because it could save them billions.

  6. Re:Dupe by Dirtside · · Score: 5, Insightful

    I would hope that of all the articles you could complain about there being a dupe of, the cure for cancer would probably be at the bottom of the list. ;)

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    "Destroy science and religion. Science would re-emerge exactly the same; but not religion." - Penn Jillette, paraphrased
  7. Re:Please, not another breakthrough by Yetihehe · · Score: 5, Insightful

    Well, chemotherapy has side effects too. Does DCA make your hairs go free? If it would be painfull only two weeks or month, is it worse than several months of pain with chemotherapy?

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  8. Re:Patentless by QuantumG · · Score: 4, Insightful

    foot the bill for the betterment of mankind. Wow, almost sounds like what governments used to be all about.
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  9. Re:Patentless by Tsugumi · · Score: 4, Insightful

    Rubbish. Firstly, it's an existing drug, so the burden of clinical trials is reduced. Secondly, governments, charities, and drug companies that make their living producing generics could fund this easily.

  10. DCA is completely useless: it harms profits by gd23ka · · Score: 5, Insightful

    Yes. You are right on the money, there are no profits to be made
    on DCA, in fact it even harms industry profits. Think of all the
    chemotherapy, surgery and radiation therapy that doesn't get done
    because of it.

    A cancer patient usually brings in more or less a cool $100,000 in
    profit, a breast cancer patient slightly less, a prostate cancer
    slightly more.

  11. Re:Patentless by jparp · · Score: 4, Insightful

    How about all those folks that "Run for the Cure" every year? They've been quite good at raising money for cancer treatments.

    There is a lot of people out their with cancer. A lot of them have money. I am sure that given sufficient evidence and a means to provide that money to the proper source, (as the original article linked to) the money will be fourth coming.

    Big-Pharma is a dinosaur that deserves whats coming to them.

    The future is of this kind of funding is in better organization of charitable donations and social lending.

  12. Re:Patentless? by MMC+Monster · · Score: 5, Insightful

    As a physician, I may squeeze patients a little bit. But that's more because HMOs and the government are squeezing me for every nickel they can. I would love to spend an hour seeing every new patient and half an hour on every followup. I am limited on how much the HMOs will pay me to see those patients, however. And my overhead is somewhat fixed (have to pay that secretary that works for me, etc.) If I spend less time seeing each patient, I get to see more patients and hopefully break even.

    Yes, I make decent income now. However, I did 8 years schooling (that I am still paying for) followed by 7 years of residency and fellowship training in which I made $50K for 80 hour weeks + overnight in hospital calls and every third weekend on call. I think I'm due a bit more than average U.S. income, thank-you-very-much.

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  13. Re:Patentless? by budgenator · · Score: 4, Insightful

    My Dr. is squezzing me and workman's comp, but when I look arround his waiting room it's obvious that about half the patient's don't have a snowball's chance in hell of ever paying the bill, yet I see them There every six weeks. I swear my doctor lives at the hospital two doctors covering a regonal burn center is insane.
    Some places have formally socialized medicine and we have informally socialized medicine

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  14. Re:Patentless? by El+Torico · · Score: 4, Insightful

    For three years, I made about $15K a year as a Soldier protecting you. You're welcome.

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    In the land of the blind, the one-eyed man is usually crucified.
  15. Re:Patentless? by Tinfoil · · Score: 4, Insightful

    I never understood the logic of that. We as a society will not let, for example, a truck driver drive for more than x number of hours in a day before they have to take a mandatory amount of time off. I forget what x equals, but it's 8-10 hours max. Yet, we'll stick a doctor into an emergency ward for days on end with said doctor only catching sleep when things are slow.

  16. Re:Patentless? by eli+pabst · · Score: 4, Insightful
    Even if you were to get a PhD in engineering or CS, you would still likely spend much less time in school and would owe much less in tuition whe you were done. Then you'd starting making a pretty nice income right away. The fact that the majority engineers and programmers have a bachelors degree means they spend *way* less in time or money. If it were about money, most doctors (with the exception of higher paying specialties like surgeons, derm, etc) would be better off going to law school or business school and making close to 6 figures right out of school instead. I know plenty of physicians who are asshats that only went into it for the money/prestige, but by far the majority of doctors are people who really care about the patients and would rather spend more time with their patients. The OPs sentiments are dead on. They just don't appreciate it when jackasses tell them they're overpaid when they work 60+ hours a week+weekends+holidays, are paying of huge loans for 10 years, and had to sacrifice a lot to get there.

     

    What is it that makes you feel your time is worth $800.00 an hour?
    You do realize how little your doctor will ever see of that $800 right?

     

    My plumber is more professional and friendly than any doctor I have ever seen. He comes to my home, does his job and courteously thanks me. He charges less than my doctor. If he can do it, why can't you?
    If your plumber fucks up the pipes, he has to come back out and fix the leak. If your doctor fucks up *your* pipes you're dead.
  17. Re:Patentless? by El+Torico · · Score: 4, Insightful

    To clarify, I was a Soldier in West Germany in the early 1980's (three minutes to midnight on the Doomsday Clock); our unit was expected to survive for about three weeks in the event of a NATO / Warsaw Pact conflict (other units were as low as a few hours). Yes, I was protecting him indirectly, just as millions of Soldiers and Police protect the rest of us (myself included) every day.

    In the 1980's, there was no such thing as deployed pay for overseas duty, and we paid all federal and state taxes as well as Social Security. Hazardous Duty Pay today is still only about $150 a month.

    Yes, we given "three hots and a cot", and our facilities were decent. However, when you are in the field, your living conditions can be a bit primitive, and you can be out there for quite a while. Yes, there were benefits, but the downside risks are very serious. You never forget the first time you are given mission load (the ammunition you will use) and told "this is not an exercise". Thankfully, I never faced combat, especially since a war in 1980's Europe would have gotten very ugly, very quickly.

    In my original post, I just wanted to point out that we each have our cross to bear and we each chose it.

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    In the land of the blind, the one-eyed man is usually crucified.