Possible Cure For Autism
Henry V .009 writes "Scientists in New Jersey are claiming that children with autism are unable to metabolize key fatty acids that fight brain-damaging inflammations. They have already developed urine/blood tests to identify at-risk children. A preventive cure to autism may be as simple as a 'therapeutic cocktail' of fatty acids. Human trials could start later this year."
... definitely, definitely.
What will happen now to the legions of slashdotters who claim to suffer from autism/aspergers ? How can i relate to Knuth now? I'm doomed.
You seem to have a strong opinion on this... were you also diagnosed with asperger's syndrome?
it won't cure autism. It sounds like the treatment would prevent the brain from being damaged, not that it would reverse any existing damage, for everyone with The Geek Syndrome.
"Scud Storm!" -- Jeremy of PurePwnage.com
*looks down at his waistline*
It would appear I have no problem metabolizing fatty acids. I'm definitely safe.
"An unarmed man can only flee from evil, and evil is not overcome by fleeing from it." Col. Jeff Cooper
I know that spelling, grammar, and punctuation, are lost causes for Slashdot editors, but proper use of quotations is easy. I didn't write the sentence "human trials could start later this year." Nor is it accurate exactly. The only "human trial" starting up later this year is a preliminary study of the effects of fatty acid supplements on autistic children aged 5-7.
Also, I'm not responsible for the story link that pops up a big Printer Dialog when you click it.
There are going to be people vocally declaring that we have no right to "cure" (or prevent, as the case may be) autism, and that it's not a disease. At the same time, others will insist that we should do everything in our power to mitigate the effects of autism, which can be quite formidable...I myself know a family friend a year younger than me who has pretty severe autism, he lives in a group home, but he plays the piano like a concert pianist (and has since he was 12) as well as being completely bilingual. He is quite intelligent but really can't function independently in society. I'm going to reserve judgement on this until the trials are completed and the results are in, but I can promise that there is going to be a HUGE amount of controversy over this.
Now they need to find a cure for printer dialogs.
'Same speed C but faster'
This is great. It's about time they tied this down to something that can be tested for so the people with real problems can get help, and all the Internet whiners can learn to deal with life instead of always searching for a cop-out.
I've been using chat programs and on online forums since 1996 and have never seen someone flame someone else and then later claim to have aspergers.
So, I just have to ask: What the hell straw man are you roundhousing to the face, chuck?
Latewire
Oh great. Now we'll have another drug to dope our kids up on. I predict an increase in the diagnoses of autism in children as soon as this gets marketed.
"Drink your fatty acid cocktail, dear, your psychiatrist has a new BMW to pay for..."
Don't blame me, I didn't vote for either of them!
Please stop spreading this lie. You are killing people by convincing them to avoid vaccination. It is more likely a result of trans-fats in food. Or a new neurological virus caused by sexual promiscuity (cerebral herpes maybe). How do I know these things? Well, both have increased at the same time as rates of autism. And, both can get a rise out of people by making them feel abused by others or powers at be.
And that, is the Modern Scientific Method.
Stop trolling.
English is easier said than done.
Sorry to reply to my own comment, but as long as we are discussing Asperger's and such, I though I'd add this note to the original issue of urine/blood based diagnosis:
...and related Wikipedia Article.
Apparently, those suffering from "non-chelated pervasive developmental delay not otherwise specified or Asperger's disorder" do not have "significantly increased median coproporphyrin levels", which is the method used in the article to diagnose the more severe forms of autism spectrum disorders. (Note: There is an increase in the median urinary porphyrins for those with Asperger's and PDD-NOS, but not sufficient to be statistically significant based upon the authors' criteria.)
Source: Nataf R, Skorupka C, Amet L, Lam A, et al. "Porphyrinuria in childhood autistic disorder: implications for environmental toxicity." Toxicol Appl Pharmacol 2006;214:99-108
>> Standing on head makes smile of frown, but rest of face also upside down.
The autism-vaccine connection was 'research'
purchased by a law firm for almost a million dollars.
Obligatory claim of relevance: I am a pediatrician with developmental training. I am also the parent of a teenager with severe autism. It is my informed (but not omniscient) opinion that the odds that this is anything other than a complete red herring are too small to measure accurately.
We will begin with the obvious problem that they are treating autism as a single disorder. We don't know a great deal about the spectrum, but we certainly know that autistic symptoms can be found in a large number of discrete conditions. "Autism" is probably a final common pathway of subtle neurologic failure, and the idea that a single enzyme is associated has been discredited repeatedly. In fact, every time we think we've found "the" cause, more research shows us that we have found, at most, "a" cause, and usually not one that is common. Fragile X syndrome, Rett's syndrome, and others were all previously lumped in as "autism", and I don't think we're done finding things.
The next obvious problem is that if we indeed have a single liposomal storage disease causing most or all autism, you would find it with brain biopsy and/or MRI. We have not found this. You would expect other commonalities as well, since failures of fat metabolism generally have organ impacts outside the brain. We have not found these. I would be unsurprised to discover that there is a rare disorder of this sort with autistic symptoms present, but it means nothing for the vast majority of individuals with autism.
Don't get me wrong - I would give the rest of my life willingly if it would cure my son. I will be grateful beyond words if this works. But it won't, any more than secretin did when it was the last great hope for autism. I have learned much in the fifteen years of my son's life, and the thing I have learned most is that people who claim to have "the cure for autism" are lying. Not always in an evil fashion, and not necessarily knowingly, but they are saying something that is not true.
This is used against autistic individuals on all levels of normal function.
m l
The general argument goes like this:
"It's okay for us to torture autistics, because anyone who can object isn't a real autistic. Therefore no one objects."
http://www.autistics.org/library/whoisautistic.ht
Unlearn.
NOTICE: This notice will appear at the bottom of all my slashdot posts.
Thimerosal has been virtually eliminated in childhood vaccines in the US, yet we see no decline in autism rates. A large scale Danish study http://pediatrics.aappublications.org/cgi/content/ full/112/3/604/ persuasively argued that there was no link between autism rates and Thimerosal. As in the US, they found that the elimination of thimerosal had no effect on the rate of autism. What causes autism? Hell if I know, but it sure doesn't seem that thimerosal does.
While I don't agree with the asshat who responded to your original post, I will tell you this. My son displayed the signs of autism far before his two year shots (typically the ones autism is blamed on). Your assessment that it has to be "caused" rather than genetic is flawed.
It took me quite a while to come to grips with the fact that my son has this condition. I've also done a lot of thinking on why so many kids today are being diagnosed with it as opposed to twenty years ago and the answer came from my Mother of all people. She saw nothing wrong with my son. "He's just a little behind" she said. "Your brother didn't start speaking until he was almost three" she said.
Explaining away the condition as some medical conspiracy is ignorance at its finest. Perhaps in the future you should study a little more and get a little more experience with topics you feel you need to comment so strongly on before you make such absurd statements (and no, the internet, while fun, is not the best place to learn if you're looking for facts).
While I appreciate the fact that you took five minutes out of your day to give the matter some thought and you decided that in your limited experience you've never heard of or seen anything that would lead you to believe autism was anything more than mercury poisoning, I'll have to side with the researchers and the doctors and the therapists I've spoken with who have actual years of experience dealing with children afflicted by this condition.
Just because you'd never heard of it in such numbers before doesn't mean they weren't there. They were simply explained away, ignored, or treated quietly while the rest of society went about its business. Not understanding a disease is not the same as it not existing.
So- of those few vaccines that still contain thimerosal, such as Fluzone (the most I can find in the tables, at 25 micrograms mercury for a 0.5 mL injection), how does that compare with what you eat?
You get twice that much by ingestion from a single gram of chunk white tuna. Or, from the Mercury Calculator, two ounces of canned albacore is 180% of what a 40-pound child should eat in a day.
Of course, injection is very different from ingestion- but the example I give is extreme. After the influenza vaccines, thimerosal levels drop off dramatically- and virtually all use of thimerosal was discontinued years ago.
So stop whining about vaccinating your kids. There are low- and no-thimerosal options for everything but straight TT (tetanus toxin), and you can get your kid stuck for tetanus without thimerosal by using Tdap or another vaccine with a tetanus component. And in another 5 years or so, we'll know for sure if the thimerosal was responsible. Until then, your kids get way more exposure from food, water, and air than vaccines.