Better Jukebox Software for Bigger Libraries?

jimjenkins1975 asks: "I recently ripped and encoded my entire CD and Vinyl library, as well as merged my home and work computer's libraries (I work at a music company so my work library is very very large). It resulted in well over 750 GB of MP3's. I was hoping to get away with using iTunes to manage this, however the XML database file has grown very large, and the application itself is non-responsive or very sluggish at best, once it has loaded up (a process that takes several minutes itself). Is there another application (preferably for Mac, but I do have a PC) with similar features out there that can handle a library of this size with aplomb?"