All Blood Converted to Type O?
UnanimousCoward writes "The BBC is reporting that scientists claim to have discovered a technique to convert all blood into Type O with the discovery of an enzyme that can strip the A and B antigens. This has implications to transform the stored blood supply into transfusable blood for all. It does not address the RH negative issue, however."
It does not address the RH negative issue, however
OK, so not everyone would be a universal recipient, but most people would be. 85% of the US population (apologies to the international community.
Those are my principles. If you don't like them I have others. -Groucho Marx
I'm actually surprised that we haven't developed synthetic blood before now. We've known about blood types for 100 years and I keep expecting to see a machine producing blood cells in the news any day now.
Provided with the proper nutrients couldn't we keep a cell alive and dividing to have an unlimited supply?
Something I didn't know before that I learned from the article: Anyone can receive type O blood without risk.
Great post!
Is half a problem not a problem?
My day job is to run a blood bank.
The enzymes discussed in the article are the next step in 25+ years working toward the goal of making blood universally compatible. The enzymes are years and years away from routine use, if they ever do make it to market. Offhand, major questions that need to be addressed include: Does it *really* work? Is the process cost-effective at manufacturing scales? Is it safe? Does the enzyme affect other proteins so people make antibodies?
Conversion of non-O RBCs to group O RBCs will make them more widely compatible, and may alleviate the shortage of group O RBCs, but does not affect Rh compatibility or the compatibility of platelets or of FFP. We would still have shortages of these products even when the process is up and running, and, so, we still need people to donate.
There are a number of guesses, comments, and half-truths posted above. I'll do my best to answer specific (on-topic!) questions posted as replies to this comment.
Teidou.