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UK Moves To Allow Human Hybrid Experiments

penguin_dance writes "The UK is apparently rethinking its ban on human hybrid experiments. If approved by regulators, '[t]he move opens the door to experiments involving every known kind of human-animal hybrid. These could include both "cytoplasmic" embryos, which are 99.9% human, and "true hybrids" carrying both human and animal genes.' Previous calls for an outright ban on all human-animal embryos outraged scientists, according to the article, who believe that 'work on human-animal hybrid embryos will greatly speed up progress in stem cell research.' The report claims there will be a provision for regulation of the research to incorporate any 'unforeseen developments.' Let the Island of Dr. Moreau comparisons begin!"

20 of 284 comments (clear)

  1. Yet more proof that the UK has gone mad by Lissajous · · Score: 1, Insightful

    Let me get this straight.....I can fuse a human with a shark, but I can't pop down to Game (even if I *am* watched on CCTV every step of the way) and pick up a copy of Manhunt 2?

    Boy, am I glad I fled that crazy, crazy country for a saner place to live.

  2. Re:What on Earth does it mean by glwtta · · Score: 5, Insightful

    In common speech the word "animal" is used to refer to animals that are not humans. There is really no way that anyone did not understand what they meant.

    You really are just trying too hard.

    --
    sic transit gloria mundi
  3. Re:Hybrids by Broken+scope · · Score: 2, Insightful

    Who gets to decide what is a pet and what is a child?

    Who gets to decide what is human and what is not?

    Who gets to decide if its okay to use hybrids for testing purposes since they resemble humans so closely?

    Maybe I'm just paranoid, but I don't think humanity is currently ready to answer those questions. Maybe i'm just so cynical that I expect people to fear anything that is near human but not quite.

    A child borne of a rape/one night stand is still a human.

    --
    You mad
  4. Re:It will happen by duggi · · Score: 2, Insightful

    I am really interested to see the results, jokes apart, cures for some major aliments can be found. This is a really good step taken, but I doubt its success , there will be lot many failures before we get to see something remotely useful. I doubt what average joe's reaction to medicine(or the product for curing a disease) would be.

    --
    http://monkeynesianeconomics.blogspot.com/
  5. Finally, by Fengpost · · Score: 2, Insightful

    they make the live action Thundercats movie. I can't wait to see the picture of Cheetara!

    --
    The purpose of writing is to inflate weak ideas, obscure poor reasoning, and inhibit clarity....Calvin
  6. Are there no better ways to spend our money by tgv · · Score: 2, Insightful

    The problems with this kind of research are ethical. So let us consider possible advantages. What is this research for?

    a) Rare diseases. Many people die in poor countries because there is no proper health care. Why fund research with possibly far reaching ethical dilemmas that might one day cure some rare disease when there are millions to be saved?

    b) Common causes of death. We now reach an average age of around 80. That's enough. There is no point in following Faust's example with the risk of getting us in troubled waters.

    My conclusion: The disadvantages outway possible advantages. These outraged scientists (BTW, I am one, just in another field) just cry for more money. This line of research is not going to give us more insight into nature, nor is it morally acceptable at this point.

    1. Re:Are there no better ways to spend our money by stranger_to_himself · · Score: 2, Insightful

      a) Rare diseases. Many people die in poor countries because there is no proper health care. Why fund research with possibly far reaching ethical dilemmas that might one day cure some rare disease when there are millions to be saved?

      That argument doesn't hold a lot of water. The reasons people die in poor countries are economic, not due to a lack medical knowledge, so by your logic, all medical research should stop until we've solved third world economics?

      b) Common causes of death. We now reach an average age of around 80. That's enough. There is no point in following Faust's example with the risk of getting us in troubled waters.

      This one makes a bit more sense, but most of this sort of research is about improving quality of life, that is in extending 'disability-free life', rather than extending lifespan itself.

    2. Re:Are there no better ways to spend our money by tgv · · Score: 2, Insightful

      a) Increasing scientific knowledge can be done in a different manner and scientific knowledge is not the highest goal. Complying with Godwin's law: remember the experiments in WWII. They got us a lot of scientific knowledge, e.g. about safe diving depths, but you'll agree that the price wasn't worth it.

      b) Faust is not someone to fuck with unless you're Mephistopheles.

    3. Re:Are there no better ways to spend our money by hey! · · Score: 2, Insightful

      But admitting this, your argument becomes circular: research is unethical if it wastes money that could go to solve social problems. Money on research is wasted if the research is unethical.

      If you want to bring the effects of research on the poor into this, you must either treat all research equally, or show why this research has effects on the poor that are peculiar to it.

      Alternatively, you need to come up with a definition of "useful" that includes pure science but not applied science that may provide new capabilities to pure science.

      With respect to lifespan extension, I think the greatest promise comes not in extending lifespan indefinitely, but extending the vigorous and productive period within our current approximate lifespans. However research into the fundamental processes of aging seem likely to be useful in this regard.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    4. Re: Are there no better ways to spend our money by tgv · · Score: 2, Insightful

      Until someone argues that there could be a great, big promise when we let them develop a little bit more. Just to see where the specialization sets in, how it is different from normal human embryo's. Perhaps we can cure some fashionable disease with it then!

      Repeat 17 times and congratulations, you're the proud father of the first Chimera(TM) and my God, will you feel sorry for it.

      So stop it, before it's too late. We can always start the investigation again if we stop now, but if we continue, we can't undo it.

    5. Re:Are there no better ways to spend our money by stranger_to_himself · · Score: 4, Insightful

      Furthermore, I don't expect any great insights from research where the basic target is mixing up genes just for the heck of it and see what comes out.

      Um.. That's bascially all that conventional plant breeders do, and you benefit from that every single day.

    6. Re:Are there no better ways to spend our money by Jtheletter · · Score: 2, Insightful

      Wow, glad you summed up a complex argument, moral dilemma, and vast as yet un-explored research field in two points. I'm hoping you were being sarcastic. If not then you, as a scientist, shift your area of research to only the most massively-important topic of the year every time it changes right? So which cancer are you curing? Or are you working on AIDS research? No? How about increasing crop yields for harsh-climate strains? Hm, inventing cheap potable water conversion techniques, or desalination? Or I guess since those things might increase our average age you'll be shunning all them and just inventing better birth control for poor populations? So which is it? Which is number one, how do you know you're doing the "Right" research right now?

      Or maybe you should get off your high horse and recognize that there are multiple avenues to be explored and the manpower and money to do so. Humanity will sow many seeds in many fields and reap knowledge from as diverse a range of research as possible to improve life for everyone. And for the record, off the top of my not-a-biologist head I could see how this research might allow us to create human-specific organs in pigs otherwise meant for slaughter anyway. Thus people involved in tragic accidents or assaults who need an organ transplant could actually get one. The logical conclusion of your ethical dilemma is that all gene manipulation of human cells is taboo. Where does that get us?

      --
      -- I'm not a pessimist, I'm a realist. It's not my fault that life sucks so much. --
  7. You know it's true by suv4x4 · · Score: 4, Insightful

    1. We're already experimenting with animals, including almost-humans (apes). They have similar self-appreciation, feelings, pain and confusion like you. We're only less sympathetic since they're not EXACTLY like us. But they are, in fact, more like us than we suspect.

    2. Experimenting with human embyos, experimenting on people will dramatically further science and improve life for the rest of us (billions). It means we need to come to terms with the fact that humans are animals as any, and experimentation is required. But how do we do that without allowing for genocide? Not simple problem, but unless we solve it, we'll all be victims to save the few from being victims.

    1. Re:You know it's true by R2.0 · · Score: 2, Insightful

      "Experimenting with human embyos, experimenting on people will dramatically further science and improve life for the rest of us (billions). It means we need to come to terms with the fact that humans are animals as any, and experimentation is required. But how do we do that without allowing for genocide? Not simple problem, but unless we solve it, we'll all be victims to save the few from being victims."

      Sure about that? There's a big difference between being a "victim" of another human's or society's desires and being a "victim of - what? Old age? Disease? Being ugly? Having a bad heart?

      You are proposing that humans be involuntarily sacrificed for the benefit of others, and your only concern is avoiding genocide? What about individual human rights? If I came up to you and said "Your organs can save the lives of 6 people (heart, liver, 2 lungs, 2 kidneys), so I'm going to kil you now", would you not object? Or would you submit to being one of the "few" victims to save the "many"?

      --
      "As God is my witness, I thought turkeys could fly." A. Carlson
  8. Re:Hybrids by stranger_to_himself · · Score: 4, Insightful

    What is it people abhor so much about a child or a new species created on purpose?

    There are lots of good reasons to be worried about this. First, there's no way of knowing what the long term medical, biological, psychological etc outcomes would be for the child. There's clearly no medical need at the individual level for this sort of thing (there might be at the social level, but that doesn't count in medical ethics). There's also no notion of consent, you couldn't retrospectivly ask the child whether they agree to be an experiment. So ethically, at the moment at least, it's a non-starter, even within the existing rules of medical ethics.

    I agree though that the "ewww" reaction and the 'abhorrence' is a bit irrational and is not a good basis for policy.

    Having said all this, medical and biological sciences will advance, and one day we're going to have to deal with this sort of thing as a real possibility. We should be starting to get the ethics sorted out now.

  9. Re:Hybrids by n+dot+l · · Score: 3, Insightful

    Who gets to decide what is a pet and what is a child?

    Who gets to decide what is human and what is not? I hate these arguments. I mean, who gets to decide whether the unusually intelligent should be given freedom or forced to invent things to service the rest of us? Who says the unusually strong shouldn't be forced to do manual labour? Who says slavery is wrong? Who gets to decide that people that suffer from deformities shouldn't be put on display and exploited for public entertainment? These are all things we've already worked out the answers to.

    The real question should be: who gets to decide that a trait which has been added to the genome by scientists purposefully rearranging DNA is unnatural and makes something inhuman (and thus not subject to existing moral codes), while the odd mutations that have been caused by exposure to radiation, or pollution, or bad drugs, etc. are natural, and that those that bear said mutations are clearly still human?

    Who gets to decide if its okay to use hybrids for testing purposes since they resemble humans so closely? I always want to add, "Right. Who gets to decide that death row inmates, or the mentally retarded, or people who's skin color varies from our own should not be used for medical experiments?" to that one. This isn't anything new in terms of moral issues. Next!

    Maybe I'm just paranoid, but I don't think humanity is currently ready to answer those questions. Humanity could answer those questions just fine if it could assert reason over the urge to declare everything an us or a them, often over the most trivial of differences...but I'm really not arguing with you because I don't have any faith in the general public's ability to think clearly about this.

    Maybe i'm just so cynical that I expect people to fear anything that is near human but not quite. Yeah. With you on the cynicism.

    For the record, I don't think avoiding the issue is right either - regardless of the fact that, yes, we're going to screw things up no matter how we approach this (or any other) new field. I mean really, imagine where we'd be if mankind had just sat around discussing the ethical issues of fire, as opposed to learning what it is and how to harness it. True, we'd never have burned all those people at the stake, but...

    A child borne of a rape/one night stand is still a human. Obviously, I think this only gets dragged into the discussion to counter the argument that we shouldn't create creatures that could only face a life of pain and misery - because it's kind of obvious that we're already perfectly capable of taking care of even the most unwanted of our own, though we don't always choose to do so.
  10. Does it occur to you by Flying+pig · · Score: 4, Insightful
    That in fact the description is intended to be sensationalist? That it plays to the religious fundamentalists who want to stop biological research? That it is NOT an accurate description of what is being done? And that some of us actually are of have been working scientists or heads of research departments, and care about accuracy of reporting because we don't like having our work, or that of others, misrepresented?

    Recently we had the case of journos talking up Craig Venter's research as producing "artificial life". I had to read his own original comments to see that he never made that claim, and in fact his own comments agreed with my own Slashdot posting on the subject.

    Science is not common speech, and attempts to make it so result in misunderstanding and sensationalism. I don't know who modded this "informative" (presumably the same people who moderated me "overrated" because that doesn't get metamoderated, but whoever you are, you clearly know diddly squit about biology.

    --
    Pining for the fjords
    1. Re:Does it occur to you by glwtta · · Score: 2, Insightful

      Science is not common speech, and attempts to make it so result in misunderstanding and sensationalism.

      I'm confused. You are saying that the strict technical meaning of "animal" includes humans - fine. So how is "human-animal hybrids" more sensationalistic than "hybrids of humans and other animals"?

      To me, the description seems to be technically accurate, if likely to be misinterpreted by some of the non-biologically-inclined readers. Really doesn't seem like they are trying to purposefully obfuscate what's going on, though.

      In fact, the only problem may be that they are being overly technical, but that's exactly what you are advocating!

      --
      sic transit gloria mundi
  11. Re:Hybrids by Anonymous Coward · · Score: 1, Insightful

    "as I don't mind abortion within the first trimester". Well, that's big of you.
    Do you think the unborn child MINDS being cut up while still alive? Gee...

    Empathy obviously isn't your strong point...

  12. Re:Instant dates. by CmdrGravy · · Score: 3, Insightful

    Sounds ideal although you equally well find your new pet spent all day crouched in a box hissing at you and all night howling in the garden and screwing your neighbours only to turn up in the morning dragging a half eaten child into the kitchen to play with for a while.

    It could all go horribly wrong !