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First Image Taken With an Ultra Low Field MRI

KentuckyFC writes "MRI machines are about to get smaller, much smaller. Most of their bulk is taken up by the huge superconducting magnets required to generate fields of a few Teslas. Now a team at the Los Alamos National Lab in New Mexico has built a machine that can produce images using a field of only a few microTesla (PDF, abstract here). So giant superconducting magnets aren't necessary, a development that has the potential to make MRI machines much smaller, perhaps even suitcase-sized. The one-page paper shows sections of the first 3D brain image taken with the device."

15 of 189 comments (clear)

  1. Hidden monkeys by LiquidCoooled · · Score: 4, Informative

    I thought the images were of monkeys at first, however when I went to have a look at MRI images of a human head was thankfully proven wrong (some of us have our monkey origins hidden better than others).

    So, for comparison here is a page with images of human heads in a normal MRI.
    (single image here)

    I hope they get the focusing better (which is what I understand the power is used for) because this will be a good progression.

    --
    liqbase :: faster than paper
    1. Re:Hidden monkeys by flyingfsck · · Score: 2, Informative
      --
      Excuse me, but please get off my Pennisetum Clandestinum, eh!
  2. Article's title is misleading by IvyKing · · Score: 3, Informative
    This may be the first image of a human head with an ultra low field MRI, but ULF MRI images have been made for at least a decade and a half. Magritek, a New Zealand company, makes a low cost unit ULF MRI system, though the image volume is limited to about one liter.


    Another company, Vista Clara, is using a novel form of ULF MRI to map groundwater.

    1. Re:Article's title is misleading by ceoyoyo · · Score: 5, Informative

      The summary is VERY incorrect.

      This isn't an ultra low field MRI, it's a DUAL field MRI. In a normal scanner you have a big, static magnetic field that polarizes the sample and remains for readout. In one of these dual field scanners you use the big field (or a bigger field, it's usually a resistive electromagnet so it can't be anywhere near as strong as a superconductor) to polarize the sample then you shut it off and use a much smaller field for readout. There are a few advantages, the one the abstract focuses on is that you can do things like MEG in a very low field. The other is that energy deposition is related to the field strength so by using a small field you can use imaging sequences that would otherwise pump too much energy into the subject.

      One of the guys working on this technology visited my lab last year. It was a very interesting presentation.

      I believe someone has produced an MR image using the Earth's magnetic field. They've certainly done nMR in the Earth's field. You can't get much lower than that on this planet.

    2. Re:Article's title is misleading by Anonymous Coward · · Score: 4, Informative

      Earth's field and low field MRI are actually relatively common. There has even been NMR work done at ~1uT in a shielded chamber.

  3. Getting there, but not there yet. Too low-rez by Animats · · Score: 2, Informative

    Very nice. The images are still very blurry (resolution 81×61×11), and the detectors, at 37mm, are big, but it's a start.

  4. for reference, Earth's magnetic field is by Anonymous Coward · · Score: 2, Informative

    about 50 microteslas http://hypertextbook.com/facts/1999/DanielleCaruso.shtml.

    according to the Fine Article:

    The measurment field in the article is 46 microteslas.
    (A "pre-polarization" field of 30 mT (milliteslas) is appled for one second before each meaurement)

  5. Re:Stronger pre-polarizatin field is used by IvyKing · · Score: 3, Informative

    The Larmour frequency for 30 mT is about 1.28 MHz, which is in the AM broadcast band. Interference is likely to be a significant problem.

  6. Re:other implications by SuperBanana · · Score: 2, Informative

    I was going to make some witty comment about the bullet not going very far, but then again lead isn't paramagnetic, is it? :)

    Nope, though not all bullets are lead.

    Jokes aside, the field is very strong and ALWAYS on. The oxygen cylinder incident killed the kid who was in the MRI machine at the time; gooooo White Plains Medical center!

    Another benefit I forgot to mention is that the machine won't need to be powered up for very long, nor will it need to be quenched in the event of an emergency (which entitles dumping all the electrical energy into heat. Sometimes accidentally, like when the liquid helium coolant drops too low.) It also opens up avenues for people who have metal implants to get MRIs. It's not just magnetic attraction that is a problem; metal can be heated up by the rapidly switching field during an actual scan. High strength MRIs already do this in your *body* because of its conductivity!(we're talking the newest, highest strength human-clinical machines. Research MRIs well exceed clinical machines, and a lot of clinical machines are only a few tesla.)

  7. Nothing _that_ new... by imsabbel · · Score: 2, Informative

    Its not like the effect used in NMR is _only_ viable at high field strengts.

    Its just that higher fields (or more correctly put, higher field gradients) allow for higher resolution.
    Looking at this publication, they archived about 5mm resulution with a 50uT field.
    Real high-end small bore scanners can get 3 orders of magniture higher.

    And the "maybe can it fit in a glovebox" part is _severely_ limited by the use of 7(!) Squids... Each of which will need a LN/LH cryosystem.

    Still, this looks quite interesting, but its not like it completely depricates the current stuff.

    --
    HI O WISE PRINCE. WHT TOOK U SO DAM LONG?
    1. Re:Nothing _that_ new... by ceoyoyo · · Score: 3, Informative

      Not quite. Higher gradients give you faster imaging. Higher fields give you better signal to noise. Better signal to noise can allow you to actually use those higher gradients without ending up with a big mess of noisy pixels.

      If you've got lots of time you can achieve more or less any resolution you want with any field strength you like. The problem is, the darn patients keep getting impatient and moving.

      The summary is pretty wildly inaccurate. This is actually a dual field scanner that uses a stronger field to polarize the sample and a weaker one for readout. It's pretty cool, but it's a niche thing... these guys want to do MEG scanning along with MRI and MEG is allergic to large magnetic fields. It won't be replacing the regular superconducting scanners and it won't be making cheap in-home scanners possible.

      You can do nMR in the Earth's magnetic field if you want to. It's actually possible to set it up at home. I think someone was selling science kits for a while.

  8. Re:I hope they do away with the tunnels by FleaPlus · · Score: 2, Informative

    I had to have several MRI & CT scans and that friggin tunnel is more than I can handle.

    I haven't seen one in person yet, but there's apparently a company which produces something called the Fonar 360, which instead of having a tunnel basically turns the entire room is a magnet. This is useful not just for reducing claustrophobia, but also hypothetically allows for surgery to occur while somebody is inside of an MRI. I think the spatial resolution however is quite a bit weaker than typical scanners.

    The same company also has an Upright MRI product, where the patient sits down with open space in front of them.

  9. Re:In home MRI scanner by ameline · · Score: 2, Informative

    For cancer scanning, you'd really want a PET (positron emission tomography)

    --
    Ian Ameline
  10. No by backslashdot · · Score: 2, Informative

    No. It can say "the machine was unable to detect any of the types of large solid tumors we can recognize".

    Do people sue pregnancy test kits if it tells them they weren't pregnant and they drank alcohol and the baby was born with problems? Or condom manufacturs for getting deadly diseases?

    If they do, they havent been very successful .. cause those products still exist on the market.

    Disclaimers. Use them.

    DISCLAIMER: The above post is not meant to encourage or discourage anyone from getting into the home MRI business. Author assumes no liability for failure of any home MRI ventures or investments. Your success may vary. Results not typical.

  11. Re:Oy! My payments... by puck01 · · Score: 2, Informative

    I believe the post you are referring to mentioned a CT scan, not an MRI. While both are imaging techniques, they are quite different in how they work. MRIs are much, much more expensive in general. They require the supercooled magnets and such. A CT is essentially using the same type of radiation as in used in a normal X-RAY to get sliced images. CTs are much faster at acquiring images and the equipment is much cheaper than an MRI. Both of the factors make it much less expensive overall.