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HP Skin Patch May Replace Needles

Iddo Genuth writes "HP and Crospon have developed a skin patch employing microneedles that barely penetrate the skin. The microneedles can replace conventional injections and deliver drugs through the skin without causing any pain. The skin patch technology also enables delivery of several drugs by one patch and the control of dosage and of administration time for each drug. It has the potential to be safer and more efficient than injections."

38 of 190 comments (clear)

  1. Well... by F-3582 · · Score: 2, Insightful

    I'd like to see someone draw blood through one of those... Should get you the clearest serum ever.

  2. In speculative fiction for a while by Anonymous Coward · · Score: 2, Interesting

    Micro-needles have been part of science fiction for at least 15 years. In Neal Stephenson's Snow Crash , one character has a sedative-filled needle implanted on her cervix in order to incapcitate a rapist.

    1. Re:In speculative fiction for a while by ozmanjusri · · Score: 4, Funny
      one character has a sedative-filled needle implanted on her cervix in order to incapcitate a rapist.

      Wouldn't a cheese-grater be quicker?

      --
      "I've got more toys than Teruhisa Kitahara."
    2. Re:In speculative fiction for a while by garbletext · · Score: 4, Funny

      Ah, yes. The Vagina Dentata. Making scary Freudian dreams come to life for over 15 years!

      For example: http://pbfcomics.com/?cid=PBF051-Zarflax.jpg

    3. Re:In speculative fiction for a while by somersault · · Score: 2, Funny

      http://www.rapestop.net/ got to wonder the type of person that would leave one of those in all the time

      --
      which is totally what she said
    4. Re:In speculative fiction for a while by DigiShaman · · Score: 2

      To slow. Should go for the bear trap instead.

      --
      Life is not for the lazy.
    5. Re:In speculative fiction for a while by jotok · · Score: 4, Insightful

      It takes some people a while to separate "risk management" and "fault" or "blame." I can't pin down why, though I have some ideas.

      I think the issue has to do with separating morally important acts with moral content from morally unimportant acts: rape has moral content, wearing this clothing or walking down that street does not.

      Here's an example using street gangs: they wear different colors to identify themselves. So if you wear a red sweatshirt and the blue shirt gang shoots you, they did an immoral act, whereas your act cannot be construed as "immoral" and therefore you can't be blamed for your own shooting.

      If you're going to allow such morally unimportant and therefore arbitrary factors when assigning blame, then you get a slippery slope where things that are not only unimportant but also beyond a person's control are used...such as your gender. So we find people saying, essentially, the man who raped the woman was not guilty--it was the woman's fault for A) being female and B) being around men, who cannot be expected to control themselves.

      The obvious remedy is not for the law to enforce women's rights, nor for women to exercise their right as human beings to defend themselves, but rather to blame the women.

      If this kind of reasoning makes sense to you, then you might be a Saudi judge.

      Now, it is perfectly reasonable to advise people on risky behaviors: watch what you wear to reduce your chances of getting shot. Don't go get so drunk you can't stand up when you're all alone. Don't hold hands walking down Crime Alley in Gotham City. And so forth. But "being vulnerable" is still not an immoral act.

      Some people do think it is, but they only want to justify their position of strength--alas, power doesn't justify itself, though powerful people wish it did.

    6. Re:In speculative fiction for a while by Kimos · · Score: 2, Informative

      The you're describing an anti-rape female condom, frequently called a Dentata.

  3. Did someone say hypospray? by garbletext · · Score: 3, Funny

    Finally, the most important star trek technology comes to the real world! Forget all that transporter, holodeck, or warp drive crap; we've got painless injections! woo!

    1. Re:Did someone say hypospray? by selex · · Score: 3, Informative

      Jet Injector. http://en.wikipedia.org/wiki/Jet_injector Already exist. From what I heard from military people who had it used on them it f**king hurts.

      Now the question is HP? Really? The people who built my printer? And laptop? I guess that development of the inkjet has other applications.

      Selex

      Really?

    2. Re:Did someone say hypospray? by Muad'Dave · · Score: 2, Funny
      phlebotomist

      Is a flobotomist someone who uses Flowbees to cut hair?

      --
      Tiller's Rule: Never use a word in written form that you've only heard and never read. You will end up looking foolish.
  4. Consider the potential abuses by Bozzio · · Score: 2, Interesting

    If this patch is reusable it could become the method of choice for heroin addicts.

    On the other hand, it would be much safer than using needles.
    You can't really share these, I assume.

    --
    I just pooped your party.
    1. Re:Consider the potential abuses by ResidntGeek · · Score: 2, Informative

      It could, certainly, but it wouldn't add anything new. The problems with heroin addiction and the defeat thereof are properties of the drug itself, and can't really be mitigated. Many drugs cause users to develop tolerance, but heroin is so much stronger that continually taking the same dose won't even bring you back to normal - you have to increase the dose just to get back to normal after cravings, never mind feeling the same effects for repeated highs. The withdrawal is severe and physically dangerous, and it can be near-impossible to go cold turkey (or anywhere close) and survive if you're in too deep. Continuous subcutaneous absorption wouldn't do anything a controlled methadone drip wouldn't do, as far as breaking addiction.

      None of this is firsthand information, of course, so the usual warnings about salt and its grains apply.

      --
      ResidntGeek
    2. Re:Consider the potential abuses by phalse+phace · · Score: 3, Funny

      If it's anything like their inkjet cartridges, it won't be reusable (or cheap).

    3. Re:Consider the potential abuses by Opportunist · · Score: 2, Insightful

      We're talking a printer manufacturer here. I bet those things have some kind of chip inside that makes dead sure you can't refill them.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    4. Re:Consider the potential abuses by Anonymous Coward · · Score: 2, Insightful

      All(?) of the opioids (heroin, oxycodone, etc.), benzodiazepans (valium, klonopin, ambien), barbiturates, and alcohol all cause attenuation over time (less effect for same amount of drug), physical withdrawal symptoms when discontinued (a majority of them can be lethal if withdrawn too quickly from a high usage scenario), and overdoses can be lethal. Nasty stuff.

      You would never inject heroin (or meth, coke etc.) in anything but a vein, though, because it would feel like someone stabbed you with a red-hot-poker, and it would take ages to get a high.

      With meth (the only one I have personal experience with), you'll occasionally have users getting high midway through an injection, losing control over the needle and pushing some of the drug into the surrounding tissue -- this is never intentional though.

      Meth doesn't have the withdrawal issues of e.g. heroin (and I don't believe it's possible to lethally OD on it based on available literature), but it destroys your life in so many other ways. The last time I looked, the recidivism rate was 94% for people who wanted to quit. Skip this one if you haven't tried it. (If you're using, you won't listen to me anyways, besides you've got this thing under control, right? ;-)

      M.L.
      (clean since Jan 1, 2006)

  5. one more brick in the wall by User+956 · · Score: 2, Funny

    The skin patch technology also enables delivery of several drugs by one patch and the control of dosage and of administration time for each drug.

    Excellent. So when does Soma come out?

    --
    The theory of relativity doesn't work right in Arkansas.
  6. Previously on Slashdot by Dr.+Eggman · · Score: 3, Informative

    Last we heard this was in the prototype phase. Btw, the search function is terrible.

    --
    Demented But Determined.
    1. Re:Previously on Slashdot by Smordnys+s'regrepsA · · Score: 2, Informative

      I'm glad someone else noticed. Does anyone know if there is anything new in this post, or are we just rehashing old news?


      Oh, and next time just use Google (site:SlashDot.org "YourPhraseHere"), it is a thousand times easier.

      --
      Just -1, Troll talking to another.
  7. Now we need sensors in those patches by Thanshin · · Score: 4, Insightful

    If this technology triumphs, the next addition should be sensors that control the release of chemicals taking the current situation into consideration.

    For example, a patch could sense the cardiac rhythm and control it chemically. Another could control blood sugar, etc.

    What I imagine is someone witnessing a car accident, taking four patches from his car's medikit putting them in different parts of the hurt person and calling an ambulance while the patches stabilize the patient.

    1. Re:Now we need sensors in those patches by Ihlosi · · Score: 4, Informative
      If this technology triumphs, the next addition should be sensors that control the release of chemicals taking the current situation into consideration.



      No company wants to open that bag of liability issues. If your device makes medical decisions (instead of leaving them to a physician), you make yourself a big fat blinking glowing target for all sorts of legal trouble. Current example: Infusion pumps. While studies show that feedback-controlled infusion pumps lead to better patient outcomes, no company wants to make them because they don't want to get slapped with a multi-million-dollar lawsuit for the one patient in a thousand who thinks he might have had a better outcome with a standard infusion pump.

    2. Re:Now we need sensors in those patches by Thanshin · · Score: 5, Insightful

      Ok, we need sensors in the patches and a better legal system that doesn't bind the minds and souls of men with ropes of fear.

    3. Re:Now we need sensors in those patches by kaizokuace · · Score: 2, Interesting

      When you talk about administering chemicals according to the situation I think of the futuristic body armor suits in many sci-fi writings. Most recently in Mass Effect where your suit can have first aid upgrades that inject you with all sorts of stuff. I would like to see performance enhancing drugs administered. Maybe when adrenaline spikes in your body (from imminent car accident or even someone tries to attack you) some drugs that increase reaction times and pain killers or whatever get shot into your blood stream.

      --
      Balderdash!
    4. Re:Now we need sensors in those patches by eth1 · · Score: 2, Funny

      No, the patches just need to detect when they've been put on an ambulance chasing lawyer and release cyanide instead of their normal payload.

  8. Re:Niccotine patch did it already? by Thanshin · · Score: 4, Informative

    Those work through the skin. Transdermal patch

    This ones enter through micro needles.

  9. Tattoos by Nefarious+Wheel · · Score: 4, Interesting
    I could imagine instant tattoos -- patches with designs on them, subcutaneous injection of inks.

    Just add alcohol.

    --
    Do not mock my vision of impractical footwear
  10. Stinging nettle by lmpeters · · Score: 3, Interesting

    This actually sounds kind of like how stinging nettle works. I recently touched some by accident, and I can assure you, the needles on the surface of that leaf are so small that I couldn't feel them at all.

    The cocktail of formic acid and histamines contained within the needles, on the other hand, were quite noticeable (ouch!). Of course, I'm assuming that HP is not planning to use this invention to deliver anything that's painful by design.

  11. Re:Pain? by Thanshin · · Score: 2, Funny

    It's a breakthrough for pussies. No, the needles are too small to go through the fur.
  12. Beware by OpenSourced · · Score: 3, Funny

    The new technology is similar to the technology employed in HP's patented process for its inkjet cartridges.

    I foresee scores of people walking around with the HP logo tattooed where the patch was. Later the advertising space will be sold to other companies. Attempts to sue will be stymied by the fact that the devices will come with an EULA that clearly states that your skin doesn't belong to you while using the device, and the device can leave residues there. You will be forced to accept the EULA or else die from your sickness, but HP's lawyers will insist that was you "free and informed decision".

    Just wait.

    --
    Rome taught me patience and assiduous application to detail. Virtues which temper the boldness of great, general views.
  13. Types of injection by Wilson_6500 · · Score: 5, Insightful

    So this is great for stuff that you can put in subcutaneously. What about intravenous injections? What about intramuscular? Intraperitoneal? What about substances that are made up of large (several micron) particles, such as the sufur colloid injections used by nuclear medicine studies? Those could get stuck in superfine-gauge needles.

    I think it's a little premature to say that this patch will replace conventional injections entirely. It might seem obvious that a patch couldn't really hope to deliver injections into the muscles without penetrating all the layers of skin, but I think it at least bears mentioning.

  14. Re:Pain? by garbletext · · Score: 2, Funny

    No, the needles are too small to go through the fur.
    actually, I prefer them shaved
  15. Novelty? by $pearhead · · Score: 2, Interesting

    How is this microneedle-thing different, from eg. this?

  16. Re:Pain? by rts008 · · Score: 2, Funny

    You prefer shaved cats? Man, that's kinky.
    How do you get the cat to hold still?

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    Down With Slashdot BETA!!! I've been around the corner and seen the oliphant; you can only abuse me from your perspecti
  17. Re:Bad headline by PCM2 · · Score: 2, Informative

    Hypodermic needle. Hypo ("under") dermic ("the skin"). Pretty commonplace tool, actually. Cannulae, on the other hand, are used for IVs.

    --
    Breakfast served all day!
  18. Re:Thank god... by muffel · · Score: 4, Funny

    'What a pussy!' you must be thinking
    Correct.
    --

    bla
  19. Re:Pain? by Anonymous Coward · · Score: 3, Insightful

    It is estimated that about 10% of people (including me) have a phobia of needles (trypanophobia). For many people, this phobia is associated with a sudden drop in blood pressure, causing fainting and such, at the time of injection. I know that I am perfectly capable of being fairly calm before getting a shot, and generally don't feel terribly afraid, but will still end up nauseous and probably faint afterwards. So I'm interested in this not so much for the pain reduction, but because this probably wouldn't cause that reaction for me. I'd love not to have to worry about fainting after getting an injection.

  20. Hmmmmm by Anonymous Coward · · Score: 2, Funny

    Ya know, im not so sure that this is want i want. HP gets enough under my skin as it is ;)

  21. Re:Wuh? by Trent+Hawkins · · Score: 2, Funny

    this might be a by product of their printer technology. Just think about it, a low level technician was working one night on an ink injector and notices "hey! I just injected my self with half a gallon of ink and didn't even notice it!". He quickly dies and his manager then presents the idea to re-design their new ink injectors in to drug injectors and makes a cool million on it.