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See-Through Fish Help Cancer Research

Hugh Pickens writes "What is transparent, swims, and helps cure cancer? Caspar the friendly fish — a zebrafish bred with a see-through body to make studying disease processes easier for rapidly changing processes such as cancer, Zebrafish are genetically similar to humans in many ways and serve as good models for human biology and disease. In one experiment, researchers inserted a fluorescent melanoma tumor into the abdominal cavity of the transparent fish and by observing the fish under a microscope, they found that the cancer cells started spreading within five days and could actually see individual cells spreading. "The process by which a tumor goes from being localized to widespread and ultimately fatal is the most vexing problem that oncologists face," says Richard White, a clinical fellow in the Stem Cell Program at Children's Hospital Boston. "We don't know why cancer cells decide to move away from their primary site to other parts in the body." Researchers created the transparent fish, (photo) by mating two existing zebrafish breeds, one that lacked a reflective skin pigment and the other without black pigment. The offspring had only yellow skin pigment, essentially appearing clear."

16 of 112 comments (clear)

  1. Fish Firday. by agent · · Score: 0, Funny

    Something new to eat. Thank you Jesus!

  2. DIY see-through zebrafish by the_kanzure · · Score: 2, Funny

    1) Figure out the genes involved via a bioinformatics database.
    2) Order the genes - look up oligonucleotide synthesis companies, or DIY with the open source machine.
    3) Download the biokit for do-it-yourself genetic engineering.
    4) ??? (tanks, supplies, tissue culture, obtaining zebra fish and feed ...) 5) See-through zebra fish.

    1. Re:DIY see-through zebrafish by Anonymous Coward · · Score: 1, Funny

      How can you possibly have a ??? step without a Profit! following it?

  3. making us invisible by tonyahn · · Score: 2, Funny

    ...now if they can only make us transparent also....

  4. Re:ew by Anonymous Coward · · Score: 3, Funny

    >Zebrafish are genetically similar to humans in many ways

    Yeah, yeah. That's what I kept telling the cops. They said, "'k, son, maybe so, but they're still underaged."

    Thank you, thank you. I'll be here in court all week. Don't forget to tip your waiter, and don't eat the fish platter.

  5. When.. by Smordnys+s'regrepsA · · Score: 3, Funny

    When do they breed see-through people, for the human studies?

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  6. Re:ew by Anonymous Coward · · Score: 2, Funny

    >> that fish looks gross

    Just wait 'till it poops.

  7. Re:That's not a transparent fish... by ezzthetic · · Score: 2, Funny
    That's not a transparent fish

    It's a space station ...

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  8. New 80's Marketing Opportunity by wildsurf · · Score: 2, Funny

    Crystal Sushi

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    Weeks of coding saves hours of planning.
  9. Re:They are? by sonchat · · Score: 2, Funny

    Zebrafish are genetically similar to humans in many ways You mean, in the same way that every other vertebrate is, or is there something special about these particular fish? Hucklebee is offended.
  10. Royal Rainbow by Valdrax · · Score: 2, Funny

    I can just picture it now... "Here's the fish you ordered sir". "But wait, its an empty plate, I don't see the fish".

    Strange. The Emperor seems quite fond of the dish...

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  11. Re:ew by omeomi · · Score: 3, Funny

    I'd like to see how you look with a fluorescent tumour inserted into your abdominal cavity.

    It would be ironic if they cured cancer, but they had to make you transparent first...

  12. The real breakthrough by Joebert · · Score: 3, Funny

    Zebrafish are genetically similar to humans in many ways and serve as good models for human biology and disease.

    Fuck cancer, I wanna be transparent too !
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  13. Re:That's not a transparent fish... by edwardpickman · · Score: 5, Funny
    THIS is a transparent fish. I have five of these, and they never cease to amaze me.

    They're pretty but having to wipe them down with Windex once a week is a pain. Oh, also they don't seem to live more than a week.

  14. you call that a transparent fish? THIS ... by rubycodez · · Score: 4, Funny

    THIS is a transparent fish:

  15. Re:ew by Bloke+down+the+pub · · Score: 3, Funny

    Being transparent would be pretty cool. You could eat loads of spinach, then loads of oranges, then beetroot and watch your insides impersonate a traffic light.

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