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First Genetically Modified Human Embryo Under Review
Wired is reporting that Cornell University researchers genetically modified a human embryo in 2007, but have only recently been gaining publicity as their work is being reviewed. "The research raises a number of thorny ethical questions. Though adding a fluorescent protein was merely a proof-of-principle step, scientists say that modified embryos could be used to research human diseases. They say embryos wouldn't be allowed to develop for more than a few weeks, much less implanted in a woman and brought to term."
Quiche?
The eternal struggle of good vs. evil begins within one's self.
A fluorescent protein? Did they want to make a baby that you can find under the black lights in a night club?
Does that mean the kid would have an annoying hum if born?
Wouldn't that mean they were murdered? That is if you accept the religious side of the house...
---- Booth was a patriot ----
I'm sure it can't have been slashdotted already. Alternate source here
Seriously though, how many people here would love to be fluorescent green?
I'd be a hit at the next rave i can tell you that for sure!
We have glowing mice and they're doing fine. Why not a glowing human? I think that would be pretty nifty. I really don't see why there would be people who are against such things. This has other implications too. Imagine if we could remove the defect that causes Huntington disease in an embryo. Would people have ethical issues with that?
No, I don't want to be preaching "gloom and doom," but it does raise ethical questions. The biggest question: are the ethical questions that such an act raises actual issues of right and wrong, or are they simply the products of Western culture and my own philosophical prejudices? Here's the corrected link.
If you haven't been down-modded lately, you aren't trying.
Sacred cows make the best hamburger.
Number 1: More intelligence. Hoo boy do we need this one implemented ASAP.
Number 2: Respiratory bypass system. No more choking to death on pretzels.
Number 3: Two hearts. Works for the Time Lords, howzabout it working for us?
Number 4: Reinforced cerebral circulatory system. No more strokes.
Number 5: Smarter immune system. Get rid of cancer and AIDS before they start, no more auto-immune diseases.
Number 6: Smart metabolism. Good-bye unwanted pounds, save your ass if you crash in the Andes without making your co-survivors menu items.
And so on. Look, we can stand some species improving. Save the default in the genes as a backup and let's get splicing here.
weirdest thing I ever saw: scientology advertising on slashdot.
Children are born to parents who don't want them, they neglect them, abuse them, and even kill them.
There are parents who know they have medical problems related to their genetics, and yet are still selfish enough to "try for one" instead of adopting one of the 50,000+ or so that die of starvation somewhere in the world.
There are people out there who believe that having a baby can help save their relationship / marriage, and so create a whole human being just so they don't have to face up to the fact that they don't belong with somebody.
There are a host of ethical issues about this genetically modified human embryo, but nothing worse than already exists in the world today.
And when the embryo is not brought to term the soul would go to hell... or would that be heaven since it hasn't committed sin yet? Wait what are the thorny ethical questions again?
So does god send unborn yet dead people to hell or heaven?
If he sends them to heaven then its sweet deal for the person involved.
If he sends them to hell... Well... I'm not sure if that is a kind and loving god. Could you worship something like that?
"I am the king of the Romans, and am superior to rules of grammar!"
-Sigismund, Holy Roman Emperor (1368-1437)
At this age they are not self aware. Basically they don't know they exist. I don't see the difference between studying an embryo of that age and studyng plants.
We are already using animals that are aware of their existance in labs. Apes can recognise themselves in front of a mirror and we are using them so I feel this is really not a big issue and we should let science go ahead.
Now I'm going to start a very heated debate. We know that babies start to be self aware around the age of 2 so if you really want to test my logic I'll tell you my opinion. We could logically use babies to make tests. Why this horrifies people is because they are attached to their own babies but since these newborns are not sentient yet, where is the harm in using "lab babies"? They would have to be grown in artificial wombs and all that to dehumanize them but logically it shouldn't be stopped.
I might be modded down for opening a can of worms but try to have fun with this ethical puzzle.
I have added fluorescent protein in the lab with e. Coli and it is very simple. There have been quite a few more unusual experiments that involve taking human brain cells and growing them in mice and adding human genes to animals. I think the door is already wide open as they can claim it is not human if it does not have 100% human genome. I wonder if this non human gene is in a human, then are they not human any more by this definition?
First, you lump all religious people (hint: this is most of the planet) into the category of "people who cause genocide." Second, you offhandedly pronounce that, on the whole, the effects of religion are evil. Then, you conclude that religious viewpoints should not be heard. I say that you can't back up any of those statements.
It would be just as easy to out-of-hand dismiss Slashdot users (the only group I can knowingly lump you into) as incapable of reasonable political debate.
The fact is, this is an ethical question. It presumes that human life is valuable, and asks whether embryos qualify, and then asks how their interests balance against the other considerations.
The idea that human life IS valuable is just as much a belief as the idea that embryos do or don't qualify as humans. Whether you call that belief "religious" or not, it's still a belief.
I happen to believe that human life is valuable because we "are endowed by our Creator with certain unalienable rights." I make no argument about the faith of the Founding Fathers, but they did start with that premise. If you toss out the Creator, I assume you have some alternate rationale, but I don't think it's reasonable to say that any religious basis for valuing human life is irrelevant.
> You are presenting one side of an issue as the only side. You've chosen the side that embryos are human and alive and thus this is murder.
Forget whether it's "murder" or not for a second (that's an emotive word that will only derail discussion) and focus on the "human" aspect of things, please.
Fertilized embryos and zygotes are living homo sapien organisms--not some other species, right? They're becoming something we all recognize as human, or would given food and shelter?
So what's the other side of that (and ONLY that--no "murder" discussion, please)? They can't feel or understand pain so it's speciesist to give them special treatment merely because they're homo sapiens. Or perhaps, "What's the difference between them and cell cultures removed from your body? Especially if we could clone those?", ignoring that fertilized embryos are becoming human and samples are not?
I merely want to understand, so no flames please. I would like to hear your reasoning and your philosophy, not your anger.
In the long run the Cornell scientists have probably done a good thing, as I'm sure this will be a milestone in manipulating our genome. A great proof of concept. But you have to wonder if, as a species, we're ready for this.
Few people would object to using genetic manipulation to eliminate diseases or birth defects. What about homosexuality? Or dark skin? Or some other socially marginalized trait that has no bearing on the genetic fitness of the individual? What effect would "enhanced humans" have on a society built by "mundane" humans?
I personally believe we don't yet have the wisdom or foresight necessary to manipulate our genes. Until we can reach some sort of ethical consensus on the how, why and when of human genome manipulation we should collectively say no.
There are *2* stages of development before the blob of a few hundred cells is considered an "embryo". First, there's the formation of the zygote after fertilization, and then there's the formation of the blastocyst. The blastocyst is basically a hollow fluid filled sphere consisting of an outer layer of trophoblast cells which eventually become the placenta and an inner blob of cells called the embryoblast which eventually forms the embryo after the blastocyst phase.
When talking of "embryos", scientists are usually talking about the extracted embryoblast cells which are pluripotent stem cells. These cells are *NOT* viable and are just that : cells -- they're not going to grow into a baby, or an "embryo" for that matter. Even I would be upset if it were found out that the real embryo, after the start of cell differentiation, had been tampered with.
To conclude, stem cells are not embryos -- they're just a multiplying blob of undifferentiated pluripotent Human cells and as such, they should be put in the same class as pond scum, although pond scum is actually far more highly developed -- the aforementioned stem cells cannot survive outside of a Petri dish (unless they're implanted into another nutrient source, such as the Human body for purposes of healing)
jdb2
If right and wrong are culturally defined (not just specific application, but the general principles), I would argue that they don't exist. There is a big difference between "I/we prefer you don't do X" and "X is wrong."
Imagine that you're walking down the street and trip on someone's foot. You're annoyed, right? Now imagine that you realize the person tripped you on purpose, and is laughing. Now you're indigent. Tripping people is wrong!
Clearly your anger has less to do with the pain of falling than with your deep-seated feeling that "it's wrong to harm others." You would not describe this as a preference.
Whatever we say about the source of morality, I think everyone feels that certain things are simply wrong. To deny this removes an important aspect of what it means to be human.
I know that someone will say that different cultures have different concepts of morality, but I don't buy it. There are different applications, yes; but no culture values cowardice and treason and murder. Some cultures defend their genocide and slavery by arguing that the victims aren't human, for example, but they do this because they must justify their actions against the standard that genocide and slavery are wrong. Our instinct to make excuses shows that we agree with the standard.
You think it's easy being green?
Your courageous and selfless spelling corrections have made me a better person.
I'll stop eating delicious sugar, fats and salt as soon as I'm genetically engineered to get the same great taste and satisfaction from eating celery and carrots.
I don't believe there is necessarily a religious connection to saying "this is wrong." Why is it wrong? For starters, do you actually believe no such creations will be allowed to come to term? If you were offered, secretly, to have a "superior, genetically enhanced" child would you not take the offer? Don't you want your offspring to be the very best they could possibly be?
Genetic modification holds the promise and the threat of changing the face of humanity. Literally in some ways. But the real problem isn't just making green people but people that are not human and do not share humanity with the rest of the people on the planet. This is a fundamental point; we can have a society because of a shared heritage. Messing around with things that at this point we have little knowledge of is an open invitation to creating a branch of the human species which shares no common heritage.
What would we, meaning the current humans on the planet, do with someone that was both human and not human? Not human because they, for example, believed and acted like they were a superior form of life and that all others were placed within their view for their own amusement? OK, one such being would be a curiosity. 100 would be a threat and 1000 would be a war. What part of the Star Trek episode "Botany Bay" did you not understand?
I'm not sure I would say this is an "ethical" problem, but it certainly is a problem that we do not have to address. We can choose not to go down this road. We, as the humans on the planet, must not go down this road as it stands a really good chance of leading to disaster, potentially on a global scale.
I personally believe we don't yet have the wisdom or foresight necessary to manipulate our genes
Nonsense. What do you think the thousands-of-years-old practice of arrangement marriages was all about? Not strictly village economics. Parents also sized up prospective mates for their kids based on the health, history, and talents of thei prospective mate and his/her family. Yeah, yeah, eugenics. Except, that's exactly what it is, and was for a long time.
We can (the old fasioned way) make new specialized breeds of livestock, dogs, and chickens with only a few decades of paying attention to cause and effect. Cultures do the same thing - it just takes longer. And that's why - whether anyone wants to admit it or not - you can spot, in a given geographic region - people that have a "peasant" look/build and other people that have an "aristrocratic" look/build. Genetic manipulation.
Don't disappoint your bird dog. Go to the range.
If you look at the bottom of the image, in the article, you can see its already developing alien head! It looks like an alien aligator ready to eat human brains. Good job science! I would elaborate further, but as an American and I can barely spell the word science.
The truth is that all men having power ought to be mistrusted. James Madison