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Single Neuron Wired To Muscle Un-Paralyzes Monkeys

GalaticGrub writes "A pair of paralyzed monkeys regained the ability to move their arms after researchers wired individual neurons to the monkeys' arm muscles. A team of researchers at the University of Washington temporarily paralyzed each monkey's arm, then rerouted brain signals from a single neuron in the motor cortex around the blocked nerve pathway via a computer. When the neuron fired above a certain rate, the computer translated the signal into a jolt of electricity to the arm muscle, causing it to contract. The monkeys practiced moving their arms by playing a video game."

57 of 180 comments (clear)

  1. Sucky job by Hatta · · Score: 5, Funny

    Who's the grad student who had to break those monkeys spines?

    --
    Give me Classic Slashdot or give me death!
    1. Re:Sucky job by FSWKU · · Score: 4, Funny

      No grad students were involved. They simply told the RIAA that the monkeys were sharing the new Metallica album on all the major P2P networks. The Schutzstaffel...err... RIAA legal team took care of the rest.

      --
      "So after all this, you make my case for me. To end this stalemate, you must die..."
    2. Re:Sucky job by couchslug · · Score: 5, Insightful

      "Who's the grad student who had to break those monkeys spines?"

      The subjects were actually grad students costumed as monkeys.
      Lab monkeys are too valuable to use.

      --
      "This post is an artistic work of fiction and falsehood. Only a fool would take anything posted here as fact."
    3. Re:Sucky job by rockrat · · Score: 5, Insightful

      No one broke the monkeys' spines. The article states that the spinal neurons innervating the wrist muscles were temporarily blocked using a local anesthetic. What's particularly amazing about this study is that the monkeys were able to quickly learn to control their wrists using the cortical neurons that the computer was monitoring, even if those neurons were not involved in control of the wrist before paralysis.

      I'm a friend of the paper's author and am certain that neither the researchers nor any sane review board would have allowed monkeys to be permanently injured to perform this study; it just wouldn't be necessary.

    4. Re:Sucky job by Ihmhi · · Score: 3, Funny

      Oooh ooh ooh I finally get to say it!

      WHOOOOOOOOOOOOOOOOSH!

    5. Re:Sucky job by Anonymous Coward · · Score: 2, Informative

      I used to work in the University of Washington monkey lab.

      The review board actually allowed lots of cruel things happen to monkeys "in the name of science."

    6. Re:Sucky job by Anonymous Coward · · Score: 3, Funny

      Actually, they used members of a Congressional committee tasked with investigating executive branch wrongdoing...

      So, spines weren't an issue.

    7. Re:Sucky job by Kashgarinn · · Score: 5, Funny

      "ooh ooh ooh" ?

      - Did one of the monkeys escape and start posting on slashdot?

    8. Re:Sucky job by Ihmhi · · Score: 2, Informative

      It was less "oooh oooh" banana and more "ooh ooh" -flails hand wildly- "teacher teacher I know I KNOW!" d:

    9. Re:Sucky job by gstoddart · · Score: 2, Insightful

      Did one of the monkeys escape and start posting on slashdot?

      It's hard to tell in the sea of infinite monkeys that were already here.

      After a while, the monkey all start to blend together and become indistinct. :-P

      Cheers

      --
      Lost at C:>. Found at C.
    10. Re:Sucky job by remmelt · · Score: 2, Informative

      Wow.

      Second post and you already invoked Godwin's law, and even on a party totally unrelated to the post.

      My hat is off to you.

    11. Re:Sucky job by initdeep · · Score: 2, Funny

      I'd bet that depends on your view of "cruel" now doesn't it.

      PETA would like to thank you for your post.

      so would the CLIT commander.

    12. Re:Sucky job by supernova_hq · · Score: 2, Insightful

      You've never been a grad student have you?

  2. Yes by eclectro · · Score: 4, Funny

    But can you teach them to type??

    --
    Take the cheese to sickbay, the doctor should see it as soon as possible - B'Elanna Torres, "Learning Curve"
    1. Re:Yes by arrenlex · · Score: 5, Funny

      But can you teach them to type??

      Of course; that's how they expect their thesis to be written.

    2. Re:Yes by owlnation · · Score: 5, Insightful

      But can you teach them to type??

      Yes. I offer Wikipedia as proof.

    3. Re:Yes by failedlogic · · Score: 2, Funny

      Since I'm going to be working on my Master's thesis soon methinks paying the university for the monkeys might not be a bad idea. But, I want to finish ASAP. I am willing to pay for a Beowulf-cluster of typing monkeys. And I want a guarantee that the monkeys will not screw-up. I do no want my thesis to be cluster-fucked!

    4. Re:Yes by oliverk · · Score: 2, Funny

      I've heard rumor that a million of them can reproduce the works of Shakespeare. Oh, and fling poo. I almost forgot that part.

      --
      ---- Please be nice in case my Slashdot karma ~= my real life karma.
    5. Re:Yes by Anonymous Coward · · Score: 2, Insightful

      *Yes. I offer Conservapedia as proof.*

      Fixed that for you.

  3. Better title would be.... by wealthychef · · Score: 5, Insightful

    "Monkeys learn to play video games." I actually think that's more amazing.

    --
    Currently hooked on AMP
    1. Re:Better title would be.... by Anonymous Coward · · Score: 5, Funny

      That gold won't farm itself...

    2. Re:Better title would be.... by Yvan256 · · Score: 4, Interesting

      Indeed, while that neuron surgery thing sounds amazing, I was more shocked at the fact that monkeys actually play videogames.

      Then I realized... Are the monkeys smarter than we thought or are we just dumberer than we think we aren't not, now what I meen?

    3. Re:Better title would be.... by Anonymous Coward · · Score: 4, Funny

      I bet they've already learned how to get around DRM.

    4. Re:Better title would be.... by oGMo · · Score: 2, Insightful

      You haven't played Halo then.

      --

      Don't think of it as a flame---it's more like an argument that does 3d6 fire damage

    5. Re:Better title would be.... by guyminuslife · · Score: 5, Funny

      You were killed by b33st13b0y.
      b33st13b0y: lol pwned
      b33st13b0y: ur mom is ghey
      b33st13b0y: suk it

      I think we've known this for quite some time.

      --
      I don't believe in time. It's a grand conspiracy designed to sell watches.
    6. Re:Better title would be.... by rockrat · · Score: 2, Insightful

      Playing video games is the standard way to teach monkeys tasks such as this. After all, we're monkeys and we don't seem to have any trouble plopping down in front of a video game for thousands of hours.

    7. Re:Better title would be.... by Anonymous Coward · · Score: 3, Funny

      1 = i

      (My apologies to anyone that works with complex numbers.)

    8. Re:Better title would be.... by lysergic.acid · · Score: 2, Informative

      we're not monkeys. we're taxonomically classified as apes though (i think).

    9. Re:Better title would be.... by 4D6963 · · Score: 3, Informative

      no one works with complex numbers, for complex numbers don't exist: they're all imaginary.

      Except the part of them that's real...

      --
      You just got troll'd!
  4. Ob. by Facetious · · Score: 5, Funny

    It was the best of times, it was the blurst of times. Blurst of times! Stupid monkey!

    --
    Let us not become the evil that we deplore.
  5. Amazing by Profane+MuthaFucka · · Score: 5, Funny

    Amazing! This is truly a wonderful time to be a monkey.

    --
    Fascism trolls keeping me up every night. When I starts a preachin', he HITS ME WITH HIS REICH!
  6. Re:hallelujah by digitalchinky · · Score: 4, Interesting

    Certainly they may be jumping for joy. Though there is more to it than just wiring an electrode to a muscle before the fat lady can sing again.

    A functional limb without any sense of its location in relation to the body is a problem, one without feeling is also a problem. Did they think about electrodes for everything else the nervous system is responsible for too?

  7. Well, I just hope by /dev/zero · · Score: 2, Funny

    they mounted a scratch monkey first.

    --

    He that breaks a thing to find out what it is has left the path of wisdom.
    -- J.R.R. Tolkien
  8. Correlation != Causation by Anonymous Coward · · Score: 4, Funny

    The researchers who published this should have 'Correlation is not causation' written in giant billboards in front of their houses.

    Just 2 monkeys regained movement after the experiment does not mean that rerouting brain signals past blocked nerve pathways using a single neuron controlled by a computer did anything at all. They should have waited until they had ruled out other possibilities, like divine intervention, before publishing results. For shame!

  9. Seems ripe for exploitation by durnurd · · Score: 5, Funny

    Also, he adds, the system would ideally be fully implantable. Whenever wires protrude through the skin, as they did in the monkey experiments, they introduce risks of infection and disruption. The group plans to tackle this problem with miniaturized components and wireless technology.

    Seems ripe for exploitation...
    "...Quit hitting yourself! Quit hitting yourself..."

    --
    --Edward Dassmesser
  10. Sooo... What if they connected a human's brain by CrazyJim1 · · Score: 5, Interesting

    Can a human control a monkey arm?
    If so, can we control its entire body?
    If so, can we do it remotely, through a wire to a cell phone.
    If so, how long until someone decides to use monkeys as freedom fighters?
    Yes, science should never go down this path, but hey, it is still possible to look down the paths

    1. Re:Sooo... What if they connected a human's brain by FooGoo · · Score: 3, Funny

      I've always wanted to create an army of monkeys bent on global domination and I am sure I am not the only one.

      --
      People who bite the hand that feeds them usually lick the boot that kicks them
    2. Re:Sooo... What if they connected a human's brain by Harmonious+Botch · · Score: 2, Funny

      I hope you're not serious. It would be far easier and quicker to use robots or human suicide-bombers or just about anything else, really.

      Yeah, but watching monkeys blow themselves up would be way more fun.

    3. Re:Sooo... What if they connected a human's brain by Better.Safe.Than.Sor · · Score: 2, Funny

      ... army of FLYING monkeys, you insensitive clod!

      --
      It's all history, man. -anon
    4. Re:Sooo... What if they connected a human's brain by kungfugleek · · Score: 2, Funny

      The nice thing about monkey armies is they make their own ammo.

  11. Shock the Monkey by afxgrin · · Score: 5, Funny

    Whoever tagged this article "shockthemonkey" is awesome.

  12. Re:oo oo oo oooo snort by Joe+Tie. · · Score: 3, Interesting

    Odd note, but monkeys seem to have a preference for holding down the s key on american keyboard layouts.

    --
    Everything will be taken away from you.
  13. Re:hallelujah by marxmarv · · Score: 3, Funny

    They have their specialization and you have yours.

    --
    /. -- the Free Republic of technology.
  14. George Bush? by Own3d-You · · Score: 2, Insightful

    This article explains everything.

  15. where's the video by heroine · · Score: 2, Interesting

    Where's the video of the mokeys playing video games with the bionic nerves?

  16. WoW by Anonymous Coward · · Score: 2, Funny

    That explains those WoW players flinging poop at me.

  17. Re:hallelujah by prod-you · · Score: 3, Insightful

    As opposed to the mechanical prosthetics that feed information back?

    Now we can reuse stuff that's already built in.

  18. Re:hallelujah by rockrat · · Score: 4, Informative

    It's certainly true that proprioception (the ability to sense joint location) and sensation of muscle tension are useful feedback systems in coordinating limb movements. It's well known in the field (I'm a neuroscientist), however, that several neurological conditions rob patients of these sensations and they're still able to move their limbs effectively (though not perfectly). I'd guess that a patient who was paralyzed wouldn't mind being able to move their arms again, even if they couldn't feel where they were without looking.

  19. sweet!! by X0563511 · · Score: 4, Insightful

    Am I the only one who's more interested in the medical significance of this, instead of the silly aspect of monkey-gaming? Holy crap guys, use your brains.

    This means that we have the potential to repair neural damage, potentially severe damage as well!

    I see particular use with pacemakers. Rather than just pulse the heart at a given frequency, read what the brain wants the heart to do, and do that! You could do the same thing for the lungs as well, although I'm not sure how often someone who damages that nerve makes it to the hospital in time.

    Other use could be with amputation victims. Helping restore function to reattached appendages/digits, or controlling prosthesis...

    I wonder if, further down the line, it would be possible to do this to sensory nerves as well, not just motor control/response...

    --
    For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
    1. Re:sweet!! by jmorris42 · · Score: 2, Insightful

      > This means that we have the potential to repair neural damage, potentially severe damage as well!

      And paraplegics will get to walk again.... no stem cells required. Ok, that is an offtopic troll, but it just needed sayin.

      If this story turns out to be the real deal it is going to be major world changing stuff. Imagine the possibilities! Implant a few sensors or better yet refine our ability to pick up on these signals without poking wires into brains and remotely control all sorts of things.

      --
      Democrat delenda est
    2. Re:sweet!! by Ihlosi · · Score: 2, Informative

      Hopefully the diaphragm is able to be connected like this, I believe it would as it behaves as a skeletal muscle?

      Yes, it does. However, the question is whether you can get the respiratory center of the brain to recognize the "bypass" - else you could breathe voluntarily, but would stop as soon as you stop thinking about it (or fall asleep, for example).

      The fun part about those is that, while binary signals may work for them, I would really prefer no sensation to the choice of "OK" and "OMG MY HAND IS ON FIRE" with no gradient between.

      Nerves also deal in binary information only, as far as the value is concerned - the intensity of the sensation is encoded in the frequency of the pulses. For low intensity, the nerve only fires once in a while, for higher intensities the frequency can go up all the way to the inverse of the refractory period (the time the nerve needs to "reset" after a pulse).

  20. Dear God, free us from religion... by Somegeek · · Score: 3, Funny

    That site is real, isn't it? For the first few minutes of reading I convinced myself that it was just a funny hoax site, but the deeper I went into it the more scared I became...

    Would it be irony if I prayed to God to free us from religion? I still don't have that whole irony thing down yet.

    --
    And as you tread the halls of sanity, You feel so glad to be, Unable to go beyond. I have a message, From another time..
    1. Re:Dear God, free us from religion... by g-san · · Score: 4, Insightful

      This is irony:

      God, please protect me from your followers.

    2. Re:Dear God, free us from religion... by Zaphod+The+42nd · · Score: 2, Interesting

      God is actually powered by Irony. And heaven is a place only for those who don't believe in it.
      (okay, that genius idea was totally Dresden Codak's, credit where credit is due.)

      --
      GCS/MU/P d- s:- a-- C++++$ UL++ P+ L++ E+ W++ N o K- w--- O M+ V- PS+++ PE Y+ PGP t+ 5- X R++ tv+ b++ DI++ D++ G+ e++ h-
  21. Re:oo oo oo oooo snort by mrdarreng · · Score: 3, Funny

    Odd note, but monkeys seem to have a preference for holding down the s key on american keyboard layouts.

    Apparently, grad students will write a thesis about anything...

  22. Re:hallelujah by gamanimatron · · Score: 3, Informative

    I wouldn't be too sure. This is just the latest in a long string of research findings that point toward an astounding degree of neural plasticity in adults. At this point, if I had to guess, I'd say that wiring one sensory nerve from the general area back to a single neuron would end up restoring a noticeable degree of "feeling".

    'Cause you know, neurons that fire together wire together.

    --
    cogito ergo dubito
  23. So, that's who beat me! by incognito84 · · Score: 2, Funny

    I just got my ass handed to me by "1337_bananaz" in Counter-Strike. Looks like we have our culprit right here.