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Doctors Will Test Gene Editing On HIV Patients

Soychemist writes "Some people have a mutation that makes them highly resistant to HIV, and scientists think that they can give that immunity to anyone with a new type of gene therapy. The first human trials will start at the University of Pennsylvania this week. Researchers will draw blood from people with drug-resistant HIV, clip the CCR5 gene out of their T-cells with a nuclease enzyme, grow the modified cells in a dish, and then return 10 billion of them to the patient's bloodstream. Those cells will be immune to the virus, and they will keep the patient's T-cell count up even if the rest are destroyed. 'We will see if it is safe and if those cells inhibit HIV replication in vivo,' said the lead researcher. 'We know they do in the test tube.'"

17 of 263 comments (clear)

  1. AIDS cured on Slashdot? by Caboosian · · Score: 3, Funny

    You don't say.

  2. Re:might as well guinea pig at that point by Anonymous Coward · · Score: 1, Funny

    Mr. Wozniac? Is that you?

    Probably shouldn't mention it at the next keynote, then.

  3. Re:might as well guinea pig at that point by RelaxedTension · · Score: 5, Funny

    Or you volunteer, and be the one to get the placebo.

  4. Re:Sounds expensive... by Anonymous Coward · · Score: 1, Funny

    Let's not besmirch the guy's education. I'm sure they had sex-ed when he was in school, but you know how it is - if you never make use of something you soon forget it.

  5. M-x genotype-mode by Anonymous Coward · · Score: 5, Funny

    You *know* there's going to be an Emacs mode for gene editing.

    1. Re:M-x genotype-mode by Anonymous Coward · · Score: 1, Funny

      Screw it, I'll just use Genepad.

  6. Re:It's about time ... by Anonymous Coward · · Score: 1, Funny

    be careful dude. I got a cigarette burn on my dick from some cocksucker on the other side of a glory hole.. Try explaining that to your wife.

  7. Re:might as well guinea pig at that point by linhares · · Score: 4, Funny

    Hope not, that would mean no more Slashdot :(

    You must be old here.

  8. Re:might as well guinea pig at that point by Anonymous Coward · · Score: 1, Funny

    What could go wrong? Barclay's Protomorphosis Syndrome.

  9. Re:might as well guinea pig at that point by binarylarry · · Score: 4, Funny

    CGI super demons... who cannot be stopped by AIDS alone.

    --
    Mod me down, my New Earth Global Warmingist friends!
  10. Re:might as well guinea pig at that point by jsse · · Score: 5, Funny

    What's the worst that could happen, they screw it up and you die?

    You'll lose all your body hair; become a human-biting-albino that're very sensitive to sunlight; start biting humans and then turn them into your kind; you'll keep your biting until the T-virus in your body because air-bourne infecting disease, when you'd find no human alive for you to bite.

    I didn't mean it'd happen, but since you asked for the worse...

  11. Re:Gene editing? by Rayban · · Score: 2, Funny

    I think of my accidental select-all, delete-key combos:

    "Oh shit... undo, undo!"

    --
    æeee!
  12. Could I have my genes edited, please? by blind+biker · · Score: 3, Funny

    "I'd like darker skin and, uh... healthy eyes? The latter is kinda more important, so if I can have only one, then that should be it.

    On the other hand, if you give discounts for multiple edits, then why not. Throw in a large-penis-gene, too. I hear that's all the rage, these days."

    --
    "The agriculture ministry is not in charge of Gundam" - Japanese ministry official.
  13. Re:might as well guinea pig at that point by CarpetShark · · Score: 3, Funny

    Do we know how the human body works? No, we do not. Do we know how diseases work? In most cases, no. If we did - Cancer is a good example of an illness known in great detail - does that mean we know what to do about it? It does not. If you have an idea of what to do - does that mean it'll work? It doesn't. If it works in lab, does that mean it'll work in a live human? It does not.

    Enough with the negativity. I want my monkey-man, goddamnit!

  14. Re:might as well guinea pig at that point by Anonymous Coward · · Score: 2, Funny

    And then you're boyfriend switches you on the real drug, it gives you a brain tumor and he almost losses his licence.

  15. Re:might as well guinea pig at that point by zwarte+piet · · Score: 3, Funny

    What if the placebo works.....

  16. Re:might as well guinea pig at that point by mcgrew · · Score: 1, Funny

    Funny...