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Drug Deletes Fearful Memories

Al writes "Technology Review has an article about a common drug that seems to 'delete' painful memories related to a fearful experience. Experiments carried out by neuro-scientists at Emory University show that propranolol, a drug commonly used to treat high blood pressure, can suppress the emotional part of a fearful memory. The results, published in Nature Neuroscience, suggest a new way to treat anxiety disorders. In recent years, scientists have discovered that the simple act of remembering a past experience requires that the memory be consolidated once again. And both animal research and some human studies have shown that during re consolidation, long-term memories — once thought to be fairly stable — can be more easily meddled with."

3 of 247 comments (clear)

  1. Eternal Sunshine by sexybomber · · Score: 4, Interesting

    Admittedly I didn't RTFA, but is this specific to just painful memories? I mean, I'd love to delete some memories I have, but I wouldn't want to run the risk of overwriting, say, my acceptance to law school, or memories of particularly good sex, for example. (Yes, strangely enough for a Slashdotter, I have had some.)

    How can the drug possibly discriminate between good and bad memories, or for that matter, any memories at all?

  2. side effects of propranolol by tyroneking · · Score: 3, Interesting

    "SIDE EFFECTS: Propranolol is generally well tolerated, and side effects are mild and transient. Rare side effects include abdominal cramps, diarrhea, constipation, fatigue, insomnia, nausea, depression, dreaming, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, numbness, tingling, cold extremities, sore throat, and shortness of breath or wheezing. "

    Lot of patients who I've dealt with who took this drug suffered from impotence and had to be changed to alternative medication - wonder if in fact all that happened is that they forgot what do with it :)

    I vaguely remember being told by a gynae doc that Pethidine had some memory loss effects too

    The article linked above also goes on to say:
    "Kindt's team has already tested whether the propranolol effect lasts longer than three days--a key requirement for therapeutic use--but she declined to give the results because they have been submitted for publication."

    So continuous treatment might be required? Side effects of prop. can be worse than the memories maybe?

    Really, what's wrong with spending money on counselling instead?

    (IANAD - but IWAP)

  3. Could be used to justify torture by straponego · · Score: 3, Interesting

    After all, if you can't remember being tortured, and there's no permanent physical damage, where's the harm?

    Also, with this or roofie-type drugs, I wouldn't be surprised if some people were willing to pay to be tortured, as long as they couldn't remember it.

    Lastly, quit referencing Eternal Sunshine. Yeah, it was okay. The original PKD story, We Can Remember it For You Wholesale, was pretty good too. Of course, they never gave credit, just like Idiocracy never credited Kornbluth's Marching Morons, despite being a verbatim copy. Pretty sure Harlan Ellison had a similar story, but I... can't remember right now.

    Oh look, the coffee just hit.