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HIV Transmission Captured On Video
Technology Review has promising news on the AIDS front: researchers have captured HIV T cell transmission on video. The upshot could be new avenues of treatment. "The resulting images and videos show that, once an infected cell adheres to a healthy cell, the HIV proteins... migrate within minutes to the contact site. At that point, large packets of virus are simultaneously released by the infected cell and internalized by the recipient cell. This efficient mode of transfer is a distinct pathway from the cell-free infection that has been the focus of most prior HIV studies, and reveals another mechanism by which the virus evades immune responses that can neutralize free virus particles within the body."
I always found biology quite fascinating. All those little buggers that can kill a human just by sheer numbers. Always scared me a little.
it still stands for Ass Injected Death Sentence
Good for keeping niggers and gays down.
Coming soon to a theater near you...
I have an idea how to stop HIV and it involves the same technology found in terminator seeds.
In a nutshell, the government sanctions the agricultural giant Monsanto to engineer a new strain of HIV virus with a limited lifespan beyond a certain generation with ability to recode the DNA as it progresses. This virus could be hostile to all the known HIV strains out in the wild and force them out. People voluntarily get infected with this new virus as means of guarding against incurable HIV infections. Since this new virus can be regulated upon demand, Monsanto can then minimize the damage for a low monthly fee by supplying you with various off switches to reduce the infection. They could set up various plans depending on your budget. Silver and Gold plans would have limited side effects to encourage you to upgrade to the Platinum plan and get better viral sterilization methods.
I think this could work.
Celebrity virus, Survivor HIV, The smallest loser, The amazing erased....
this blurb reads like researcher have been ignoring cell-to-cell contamination for the last 20 years and only tried to get a cure for "free virus" to cell contamination. I hope it's not what actually happened that would be sad. Nice video though.
everyone knows it's a homo/nigger disease. if your a memeber of GNAA your really fucked.
Due to AIDS.
Protein dynamics can be affected by alterations to the protein itself. In this case, the gag protein had GFP inserted into it. GFP itself dimerizes weakly, and would add some size and weight to the protein. Does anyone know how they are sure what they're seeing matches normal Gag dynamics? The paper says "This virus faithfully reveals Gag localization, allowing infected cells and viral particles to be tracked with high sensitivity" citing an earlier paper by the same authors. That paper showed that it was not behaving like GFP alone (and was mostly over my head), but I didn't notice anything that proved the modified GAG behaved exactly like normal GAG. The protein does seem to be doing it's job and helping the virus infect, which suggests it's not rendering GAG useless, but doesn't prove it behaves in the exact same way.
It seems to me that if you're going to say "large packets of virus are simultaneously released by the infected cell and internalized by the recipient cell" that you should be sure those large packets of virus are normal and not just a result of adding GFP onto it. I'm not a virologist though, so I'm probably just missing something.
My right hand was disappointed by this video.
I saw AIDS transmission in that movie "Shaving Ryan's Privates".
You'll just love this then. Humans have ten times more bacteria that human cells.
...is this tagged "pr0n"?! Does pr0n gives you AIDS?
I'd turned Adblock off for debugging on my browser - noticed annoying Real Basic ad on slashdot homepage. Is it me or anyone else has noticed the fact that these bastards are scamming on sqlite and other FOSS tools ?
You have been foreskinned
Why do sites do it? The page linked in the article has at least three embedded videos that start playing all at once. Youtube is the worst offender. You click on a link to open it in the background so you can read it later (perhaps after you've finished reading the page it was linked from), and you hear all sorts of noise coming from your computer because the damn video started playing in the background already! STOP DOING THIS!
Just kidding.
Step 1: Take a sample of blood of the HIV - infected patient
Step 2: Put it in a blender that will evenly distribute white blood cell membranes throughout
Step 3: Inject sample back into HIV patient
Step 4: HIV infected cells' membranes are weakened when they contact white blood cell membranes
Step 5: HIV viruses are now without protection
Step 6: Inject antivirals into HIV patient
Step 7: Cure and PROFIT!
The "funny" thing about HIV is that, if it killed instantly (days or weeks) people would be MUCH more apt to be careful and NOT GET IT it because it's completely preventable aside from rape, unknowingly getting it through blood transfusions (rare) etc.
Sell tomorrow to enjoy today.
Just like global warming, the idea that HIV causes AIDS is a consensus, but the proof is a wee bit lacking. James Hogan has written several blog posts on this topic. Just like global warming, there is too much money flowing into AIDS research and drugs for anyone to want to rock the boat...
Enjoy life! This is not a dress rehearsal.
I think the interesting part about this discovery is that aids is traveling from cell to cell without the need to release virons to float around hoping to find a cell. I don't recall hearing about any other virus that spreads by cell-to-cell contact. It appears as though the infected cell press up against an uninfected cell, form a pocket between them (that is not connected to "outside" and then release some virons into this pocket. The virons contain the necessary "key" to get into a cell, but normally their odds are not good simply because they have to float around and hope to bump into a T cell, one at a time, in just the right way.
This process has several advantages. First, it's not wasting virons by simply multiplying them inside the cell until the cell bursts, leaving the virons to float around hoping for a chance contact. Second, since the body isn't being flooded with virons, it severely delays and slows the auto immune response of the body which isn't going to react anywhere near as fast to such a low-volume threat of a handful of virons leaking out now and then vs thousands popping onto the scene continually. Third, in addition to being hand-delivered to a target cell, there's a ton of them at the contact site concentrated right on the target cell's doorstep, not just one, so infection is pretty much guaranteed.
It's sort of the difference between a country sending an "army" to their enemy, by stirring up a villagefull of people to go attack on their own individually, vs assembling a strike force and attacking at one spot on the wall all at once. Clearly the latter is more effective.
Scarry stuff. AIDS looks to have evolved a very potent new method of infection. It's too bad we don't know more about how this process works. AIDS is probably throttling its viron production so the infected cell survives to infect other cells, rather than multiplying virons as fast as possible to get the most of them released into the body as fast as possible. Interferfon iirc slows the replication of AIDS virons inside the cell, so it makes sense that throttling an already throttled process should be an effective treatment.
If a cell has been taken over and is personally going to another cell and staging an attack, this may be a very difficult problem to overcome. Small, relatively inert virons can only hope for a chance contact in just the right way with a target cell. An entire cell coming to get you is a bit more like a bacteria problem, they have a heck of a lot more resources at their disposal. It's like the enemy taking over one of your tanks, vs coming at you as a walking soldier. Difference is, when the enemy "gets you", he doesn't destroy your tank... he dumps some men INTO your tank and now he has TWO tanks.
What this all boils down to is AIDS has found a new way to use the cells it hijacks. Most other viruses use them as self-destructing viron factories, and a few as places to hide and lay dormant for later relapse. But using cells as lingering attack platforms is just plain scarry.
I work for the Department of Redundancy Department.
It's called gay porn.
I really thought this was going to be an idle article.
http://www.theonion.com/content/node/29215
I'm still not sold. Can anyone from Kansas grab a science book and find me the section about the weaknesses of this "theory"?
I am a v1ral sig. Plse c0py me and h3lp me spread. Thank y0u?
Object "Humor" apparently has no reference.
Many Muslims think jokes about Mohammed are worth cutting your head off.
Nothing is off limits in humor, or there is no humor.
And while it is possible to get HIV by other means, the main explosion of the disease in this country started with gays. Take that, all those who said gays never contributed anything to society!
We found a cure! All you have to do is inject yourselves with lots of cash! Yipee!
The Pink PC Police are gonna get me now! They'll make me watch Will and Grace reruns for 24 hours straight as punishment. But wouldn't that be considered torture?
Even my gay friends can laugh at gay jokes better than you can. Actually, they told me most of the ones I know.
Time to send your sacred cow to the slaughterhouse.
I've given the matter less thought than the length of this post would indicate
LOL, that cracked me up!
Good judgement comes from experience, and experience comes from bad judgement.
- W. Wriston, former Citibank CEO
But aren't we all dying, day by day? Some of use are just dying more quickly and predictably than others.
Common sense is to not joke with people who can't take a joke
Anyone have a torrent for this? I'm getting wood just thinking about it.