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Robot Makes Scientific Discovery (Mostly) On Its Own

Hugh Pickens writes "A science-savvy robot called Adam has successfully developed and tested its first scientific hypothesis, discovering that certain genes in baker's yeast code for specific enzymes which encourage biochemical reactions in yeast, then ran an experiment with its lab hardware to test its predictions, and analyzed the results, all without human intervention. Adam was equipped with a database on genes that are known to be present in bacteria, mice and people, so it knew roughly where it should search in the genetic material for the lysine gene in baker's yeast, Saccharomyces cerevisiae. Ross King, a computer scientist and biologist at Aberystwyth University, first created a computer that could generate hypotheses and perform experiments five years ago. 'This is one of the first systems to get [artificial intelligence] to try and control laboratory automation,' King says. '[Current robots] tend to do one thing or a sequence of things. The complexity of Adam is that it has cycles.' Adam has cost roughly $1 million to develop and the software that drives Adam's thought process sits on three computers, allowing Adam to investigate a thousand experiments a day and still keep track of all the results better than humans can. King's group has also created another robot scientist called Eve dedicated to screening chemical compounds for new pharmaceutical drugs that could combat diseases such as malaria.

52 of 250 comments (clear)

  1. Please, fellow slashdotters... by Toonol · · Score: 4, Funny

    If I ever do cutting edge research on robot AI, please punch me if I try to name my new robots "Adam" or "Eve".

    1. Re:Please, fellow slashdotters... by Anonymous Coward · · Score: 5, Funny

      I'd shoot you if you named it Skynet.

    2. Re:Please, fellow slashdotters... by fuzzyfuzzyfungus · · Score: 5, Funny

      Don't worry, "Caine" is programmed to develop innovative interpersonal strategies autonomously. Nothing to worry about.

    3. Re:Please, fellow slashdotters... by Anthony_Cargile · · Score: 4, Funny

      I'd shoot you if you named it Skynet.

      I was waiting for that. Second comment from the top, we've achieved a new level of predictability.

    4. Re:Please, fellow slashdotters... by RuBLed · · Score: 4, Funny

      The third robot would be aptly named Bob

    5. Re:Please, fellow slashdotters... by clarkkent09 · · Score: 5, Funny

      I hope they don't put it to a vote or it will be called Colbert

      --
      Negative moral value of force outweighs the positive value of good intentions.
    6. Re:Please, fellow slashdotters... by MadKeithV · · Score: 5, Funny

      I'd shoot you if you named it Skynet.

      I was waiting for that. Second comment from the top, we've achieved a new level of predictability.

      Okay, good. That means my /. AI is nearing perfection. I think I'll call it KDawson.

    7. Re:Please, fellow slashdotters... by Barsteward · · Score: 2, Insightful

      It should have been Marvin, the paranoid android with the brain the size of a planet

      --
      "The hands that help are better far than lips that pray." - Robert Ingersoll (1833-1899)
    8. Re:Please, fellow slashdotters... by Ronald+Dumsfeld · · Score: 2, Interesting

      I'd shoot you if you named it Skynet.

      I was waiting for that. Second comment from the top, we've achieved a new level of predictability.

      Count yourself lucky - The Belgian telco, Belgacom, decided when they were getting into the Internet business to call their ISP "Skynet" - check http://www.skynet.be/

      --
      Where's the Kaboom?
      There's supposed to be an Earth-shattering Kaboom.
  2. Call me when by Culture20 · · Score: 4, Funny

    ... it starts experimenting with inter-dimensional portal guns.

    1. Re:Call me when by nospam007 · · Score: 3, Funny

      Call me when it begins faking results to get published.

  3. Time for... by oldhack · · Score: 2, Funny

    the union of scientists. You thought Teamsters were nasty? You ain't seen jack squat. WE SPLICE GENES!!! WE SPLIT ATOMS!!! WE (probably) MAKE BLACKHOLES!!!

    Ross King, gutless traitor, you and your tin cans, your names will live in infamy.

    --
    Fuck systemd. Fuck Redhat. Fuck Soylent, too. Wait, scratch the last one.
  4. But... by tsotha · · Score: 5, Funny

    Oh, sure, it's neat-o. But you could probably afford hundreds of grad students to do the work for the same price.

    1. Re:But... by wizardforce · · Score: 4, Informative

      You joke but really undergrads are cheaper than graduate students... At least from my experience working in a biology lab in college. It was/is common practice to recruit undergrads to do free work for the labs. The undergrad gets some experience in the field and the lab gets free labor in exchange for dealing with the inexperience of the average undergrad.

      --
      Sigs are too short to say anything truly profound so read the above post instead.
    2. Re:But... by Saysys · · Score: 5, Insightful

      "in exchange for dealing with the inexperience of the average undergrad."

      THAT Sr. is an expensive proposition.

    3. Re:But... by Anonymous Coward · · Score: 4, Funny

      That's nothing, you could probably get some hobos to do the work for free and save some money by having them eat the hazardous biological waste rather than disposing of it.

    4. Re:But... by Profane+MuthaFucka · · Score: 5, Funny

      Yes, but there are no ethical rules against watching your two lab robots fuck each other.

      --
      Fascism trolls keeping me up every night. When I starts a preachin', he HITS ME WITH HIS REICH!
    5. Re:But... by fuzzyfuzzyfungus · · Score: 4, Informative

      In terms of R&D, certainly, the status quo is cheaper. In terms of actually doing the work, though, I wouldn't be so sure. Much of science involves quite repetitive manipulation of samples, numerous instances of the same thing, tweaked variants in parallel, or both. Huge amounts of labor that is reasonably easy to characterize; but needs to be done precisely and without error.

      The case of electronics assembly is arguably analogous. Humans are cheap; but (quite expensive) pick and place machines are ubiquitous. Why? Because they are faster, more precise, and more consistent than humans.

      It is already starting. This piece describes a massive robot setup for processing brain samples(cue: whatcouldpossiblygowrong). In high volume gene sequencing, automated equipment is common enough to essentially be a stock photo cliche by now.

    6. Re:But... by Narnie · · Score: 5, Interesting

      Yes, but there are no ethical rules against watching your two lab robots fuck each other.

      I'm sure with the right thesis, you can get away with watching student volunteers fucking each other.

      --
      greed@All_Evils:~#
    7. Re:But... by Arthur+Grumbine · · Score: 2, Funny

      Will we one day see a scientific institution operated solely on robots?

      Depends on how heavy the institution is, and how strong the robots are, of course...

      --
      Now that I think about it, I'm pretty sure everything I just said is completely wrong.
    8. Re:But... by Logic+Worshipper · · Score: 5, Funny

      If you're a Windows system admin, you get paid to watch computers fuck eachother.

    9. Re:But... by derGoldstein · · Score: 2, Funny

      You're also promoting unsafe sex, what with the viruses and all...

      --
      Entomologically speaking, the spider is not a bug, it's a feature.
    10. Re:But... by gerddie · · Score: 2, Interesting

      While you are thinking about the right thesis, others are already work on it.

    11. Re:But... by Bowling+Moses · · Score: 2, Interesting

      That's not all that funny. I know someone who went on sabbatical to a Chinese university a couple years ago. They're building brand new high-tech bioscience labs but not the necessary infrastructure to support them properly. There were no facilities at that particular university, one of the top ten in China, for handling hazardous waste. Hazardous liquids are just poured down the drain, nothing for disposal was autoclaved. He saw a peasant (his term) poking through the trash and yes, eat the agar out of a petri dish. The rest of the trash is often picked over by other peasants for any sort of plastic that could be reused or recycled. What's left just got mixed in with other municipal trash at the dump. What's even scarier is that they're building a level three biohazard facility nearby, right in the middle of the city.

  5. Re:Robot discovers Humans "unnecessary"... by BikeHelmet · · Score: 2, Interesting

    I think this is a more limited type of thought. The scope is limited to thinking about genes, genetic material, and identifying similarities between genetic code from multiple species, then trying experiments before proceeding and trying another experiment.

    Effectively it is guessing, examining the result, comparing it in fancy statistical ways, then making another guess. The end result is it discovers something faster than humans could.

    Now... pair it with object recognition, and you're one step closer to Skynet!

  6. Re:Robot discovers Humans "unnecessary"... by anagama · · Score: 3, Funny

    No kidding. Let's get Ron Moore to pilot it and himself into the sun.

    --
    What changed under Obama? Nothing Good
  7. A bit of a stretch by derGoldstein · · Score: 5, Insightful

    '[Current robots] tend to do one thing or a sequence of things. The complexity of Adam is that it has cycles.'

    I think this is called "flow control". This was invented before electricity. It was around before the term "science" existed.

    So this is the first time it's applied to *this specific* operation. It's been around in robotics ever since there were "robots".

    Here's a good example.

    --
    Entomologically speaking, the spider is not a bug, it's a feature.
  8. Eh hehh... by djupedal · · Score: 3, Insightful

    "...the software that drives Adam's thought process sits on three computers, allowing Adam to investigate a thousand experiments a day and still keep track of all the results better than humans can."

    There is no 'thought process'. 1's & 0's...that's it. Anthropomorphising the over priced little key-puncher isn't fooling anyone.

    Give me $1 mil and I'll put a scare into Adam that he won't soon forget. I can read 3k WPM as well as raw postscript, palms, tarot cards and bar codes with the naked eye. I can intuit nearly 30 spoken languages on body english alone and smell phony money at the bottom of a sweaty pocket. I don't need no stink'n badges and I know when to cross to the other side of the street. Adam might get better press, but until it can order at a drive thru and sort used car parts based on cross-over and eBay thru-put, I'm comfortable sleeping in.

    1. Re:Eh hehh... by camperdave · · Score: 2, Informative

      With neurons, its more pulse frequency than voltage.

      --
      When our name is on the back of your car, we're behind you all the way!
  9. Personal by mapkinase · · Score: 4, Interesting

    I knew that Ross was up to something bigger than protein secondary structure prediction when I met him 15 years ago at ICRF. He was a great Prolog fan then. Now he has probably bunch of graduate students coding for him.

    --
    I do not believe in karma. "Funny"=-6. Do good and forbid evil. Yours, Oft-Offtopic Flamebaiting Troll.
  10. Gender bender by Mr_Icon · · Score: 5, Funny

    The complexity of Adam is that it has cycles.

    No, no, no -- the complexity of *Eve* is that it has cycles.

    --
    If you open yourself to the foo, You and foo become one.
  11. Bender would say... by Eil · · Score: 2, Funny

    Well, we're boned.

  12. Re:Robot discovers Humans "unnecessary"... by cong06 · · Score: 5, Insightful

    See, what people fail to see is this requires not only Strong AI but also a programmed Malicious intent.

    People keep assuming that if we build a robot that can emulate some of our thought, it will emulate our motives also

    Since we program it, it will only emulate the motives we give it. Emulating motives that are abstract enough to eventually lead back to our demise are quite complex

  13. Are we ..? by louzer · · Score: 2, Insightful

    I get a feeling we are already generating & testing hypothesises for someone/something bigger than us like in Asimov's The Last Answer.

    --
    Heroes die once, cowards live longer.
  14. Re:Robot discovers Humans "unnecessary"... by tnk1 · · Score: 2, Funny

    What if it concludes that humans are genetically inefficient and decides to replace them with a specie designed by itself?

    Humans replaced by coins? Now that is a dystopian future that even Philip K. Dick never considered.

    May God have mercy on us.

  15. The first step to a singularity? by moderatorrater · · Score: 3, Funny

    Isn't the first requirement for a singularity be that it's able to improve itself, thus leading to an accelerating growth that ends in the subjugation of humanity? If so, wouldn't it be prudent to withhold knowledge of the scientific method as long as possible?

    1. Re:The first step to a singularity? by Kjella · · Score: 2, Interesting

      Isn't the first requirement for a singularity be that it's able to improve itself, thus leading to an accelerating growth that ends in the subjugation of humanity?

      We've had that for years with simple statistics keeping, neural networks, evolutionary algorithms and other ways of limited learning. You can have a learning chess computer that'll run circles around me yet it's completely harmless because it's not self-aware - it does not understand what it means to be turned off.

      I'd be much more fascinated by a robot that given access to its own schematics etc. was to implement its own survivability routine like avoiding excess heat, cold, pressure, electrical jolts, water damage, corrosion, metal fatigue and so on and found pressing the "off" button as one of the identified threats to its survival. Not self-awareness in a human sense but enough logic to recognize the puppeteer.

      --
      Live today, because you never know what tomorrow brings
    2. Re:The first step to a singularity? by Anonymous Coward · · Score: 2, Funny

      Why? So it can feel bad after it's killed us all?

    3. Re:The first step to a singularity? by Chris+Burke · · Score: 2, Insightful

      I'd be much more fascinated by a robot that given access to its own schematics etc. was to implement its own survivability routine like avoiding excess heat, cold, pressure, electrical jolts, water damage, corrosion, metal fatigue and so on and found pressing the "off" button as one of the identified threats to its survival. Not self-awareness in a human sense but enough logic to recognize the puppeteer.

      I would like to think that the robot would be rational about it and realize that "Off" was an orderly shut down and an intentional and reversible condition, while shorting due to water was probably neither. The robot would hopefully go so far as to realize that the Off state was a good way to protect itself from certain hazards, so if it gets stuck in the rain it'd shut itself off to save itself, or if you told it that you were going to turn it off to protect it during transport it'd be okay with that instead of going berserk and killing you. Though if you said you were going to turn it off in order to cannibalize some critical component you needed for something else, preventing it from being able to turn back on, then you need to watch out.

      Are you listening Mr. Pitt?

      --

      The enemies of Democracy are
  16. Robot or automated lab? by f2x · · Score: 3, Informative

    This probably isn't the most helpful commentary, but it's a slight rant on semantics.

    I used to work with Motoman K6's a few years back. Using these robots, we performed plasma cutting, arc welding, material handling, etc... Just looking at the K6, you knew it was a robot. Watching a robot work in a cell after you've trained it to do it's job is a very rewarding experience. Of course we also had other machines that were also very complex in their tasks, but we didn't consider them robots. CNC mills and lathes, pipe benders, other machines that ran autonomously that also had to be programmed and synchronized with the flow of production. Sometimes the line resembled a kind of demented Rube Goldberg contraption, but we were somewhat strict to define only the articulated manipulators themselves as robots.

    So when I saw this pile of servos in a glass cleanroom set to the over-dramatic theme of "Bonanza Reloaded", I thought, "Yeah, that's nice, but... It just doesn't strike me as a 'robot' so much as it does an automated bio lab."

    And yes, I realize there were clearly robots within the cell, but calling the unit as a whole a "robot" just irks me a little.

    Of course in the spirit of all the other bad jokes I've seen posted, do you think this "robot" will use it's genetic findings with the yeast cells to perfect the most delicious and moist cake recipe ever?

    --
    Blessed with all the brains that God gave a duck's ass, and twice the charisma.
  17. Re:Robot discovers Humans "unnecessary"... by andy.ruddock · · Score: 4, Funny

    We could always build them with OFF switches as well.

    --
    God: An invisible friend for grown-ups.
  18. Automated Mathematician by camperdave · · Score: 3, Interesting

    This reminds me of the Automated Mathematician (AM) program I read about in an AI course (or was it an old Byte magazine?). This program was programmed with a bunch of axioms, and basic strategies. It looked for "interesting things", like what happens when you apply identical arguments to a two argument function. As I recall, it discovered for itself the concept of prime numbers. It applied what it learned and came up with the theorem that all angles can be expressed as the sum of two prime angles (or something like that).

    This seems to be doing the same thing: mixing and matching patterns, looking for interesting coincidences, and then testing for them. The only difference is that this is doing it with real world biological samples, and not abstract mathematical constructs.

    --
    When our name is on the back of your car, we're behind you all the way!
  19. Re:Robot discovers Humans "unnecessary"... by Failed+Physicist · · Score: 3, Interesting

    Not necessarily. The least elegant way to create strong AI is probably to brute force simulate a whole brain down to nearly every neurotransmitter molecule, something which futurists argue will be doable by supercomputers around 2020.
    This is a worst case solution since it would imply that the brain is not understood yet and instead of having a simpler model that can provide the same level of strong AI we just throw raw power at it.
    In this case, the AI would theoritically emerge out of the complexity of the system and although malicious intent wouldn't be programmed in (neither would anything else) the system might learn it by himself.

  20. The end of science by eskayp · · Score: 4, Insightful

    This is terrible.
    No experimenter bias to worry about.
    Programmable for effective randomization.
    Truly double blind capable.
    Can counteract the Placebo effect.
    No ego to bruise.
    It's the end of science as we know it.

    --
    I didn't desert Windows; Windows deserted me: BSOD
  21. Lysine? by Anenome · · Score: 4, Funny

    So, our future AI overlords begin their research with the Lysine Contingency? Should we be worried?

    --
    "I Don't Have Enough Faith to be an Atheist"
    1. Re:Lysine? by juhaz · · Score: 2, Funny

      So, our future AI overlords begin their research with the Lysine Contingency? Should we be worried?

      Of course we should. Next thing you know, they'll be cloning dinosaur shock troops.

  22. so after all this grad school... by onionlee · · Score: 2, Funny

    damn! i got this phd for nothing now! D:

  23. Software AI == Cold fusion by Henkc · · Score: 3, Interesting
    Academics have been poking away on software AI for decades (also ANN) - I can't help feeling that this is a dead-end in the same way that cold fusion is, even though it's intellectually (hacking) fascinating.

    What's far more fascinating and promising is the development of hardware neural nets. To put it into perspective:

    Since the neurons are so small, the system runs 100,000 times faster than the biological equivalent and 10 million times faster than a software simulation. "We can simulate a day in one second," Meier notes.

    10 million times faster than software? That's like jumping from an abacus to a Pentium.

    I just hope these folks continue to receive the funding they need.

  24. Re:Throwing darts by kkrajewski · · Score: 2, Funny

    I for one welcome our infinite Shakespearian typewriter-monkey overlords.

  25. Re:Robot discovers Humans "unnecessary"... by jadin · · Score: 2, Insightful

    I always thought the point of AI was self-learning (and or self-aware). Meaning you can program it to only emulate the motives you want, but what's to stop it from discovering the ones we avoided on it's own?

  26. Re:Robot discovers Humans "unnecessary"... by maxwell+demon · · Score: 2, Interesting

    Motives are not just the result of reasoning. Reasoning can only give you the possible consequences of any action. Reasoning alone cannot give any indication whether those consequences are things to aim at, or things to avoid. At some point you must resort to another way of judging. That other way can be:

    • Emotions: You just feel it's not right.
    • Rules which you have been given and which you just believe (because you cannot derive or disprove them from other knowledge).

    Any autonomous AI would have to have such a system of final rules. Those rules would effectively determine the motives. This of course means that they should be crafted very carefully, and that if there's ever a conflict between those basic rules, it should not decide by itself, but get the information from a trusted human (of course one problem would be to determine who's that trusted human).

    --
    The Tao of math: The numbers you can count are not the real numbers.
  27. Re:Robot discovers Humans "unnecessary"... by gknoy · · Score: 2, Insightful

    See, what people fail to see is this requires not only Strong AI but also a programmed Malicious intent.

    I disagree. For an AI to determine that we are suboptimal, and replace/eradicate us, it doesn't need malicious intent, merely a calculation that things would be Better (by whatever metric) without us, and a lack of adequately expressed "don't kill the humans" controls.

    Maliciousness implies wanting to see someone else be harmed. There's a difference between WANTING to harm us and "merely" recognizing that we are inferior, poorly suited for space expansion, and will eventually starve ourselves out of existence on this planet. A poorly constructed AI (or perhaps a very savvy one? ;)) might decide that the way to spare the human race (at a much larger population density) the suffering of starvation is just to kill us all now. That's not malice, though you might be able to consider it a bit Machiavellian.